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Energy Efficient Clothes Dryer with IR Heating and Electrostatic Precipitator

The project goal was to develop a revolutionary energy saving technology for residential clothes drying. The team developed an IR (infrared) heating system and NESP (Nebulizer and Electro-Static Precipitator) for integration into a ventless clothes dryer. The proposed technology addresses two of the major inefficiencies in current electric vented dryers by providing effective energy transfer for the removal of the water and recapture of the vapor latent heat. The IR heaters operating in the mid wave (2.5-10um) are very efficient as they target the 3-micron peak absorption of the water molecule. This allows direct energy absorption, unlike conventional element heaters where heat is transferred by convection. The low power NESP removes water vapor from the exhausted stream and recaptures the latent heat in the ESP (Electro-Static Precipitator) exchanger section. This allows the warm dry air to be recirculated back into the drum for additional efficiency savings. The remaining majority of the dryer hardware stays the same. Summing the efficiency gain from the two subcomponents we anticipated the EF (Efficiency Factor) to exceed the goal of 4.04. EF is obtained by dividing the weight (lbs) of water removed by the energy (kWhr) used, where the test load size is 8.45 lbs of bone dry clothing wetted to 57.5% or 4.8lbs of water, and dried to a remaining moisture content of 2.5-5%. Additional benefits include not having to recondition (heat or cool) the large amounts of make-up air to replace the air exhausted by a vented dryer. It was anticipated that the NESP/heat exchanger would be the most challenging and highest risk element in the program. Therefore, the team focused their efforts during Phase 1 of the program on the design, construction, testing, and optimization of the NESP/heat exchanger. At the end Phase 1, the team compared the performance of the NESP/heat exchanger with the system level requirements and made a Go/No-Go decision on proceeding with the second portion of the program. Phase 2 of the program was structured to develop the IR heating system and then integrate it and the NESP/heat exchanger into a residential clothes dryer prototype for final testing. The proposed technology utilizes heat recovery which is known to have the biggest impact on dryer efficiency. The two current mainstream recovery approaches are air to air exchangers and heat pump condenser systems. Air to air exchanges can be very efficient but require large surface areas which are prone to fouling from uncaptured lint. Dryers based on heat pump condenser recovery systems have shown efficiency improvements of 20–60% and are commercially available. The issue with a heat pump condenser approach is the added cost, as typical prices are twice that of standard vented dryers and they are only available in small to medium capacities. The energy factor (EF) for these systems is 5.50 to 6.88 pounds/kWh compared to conventional dryers at 2.75 to 3.67 pounds/kWh. The efficiency improvements for the proposed technology come from the use of IR heating and the NESP. As the concept is in its infancy, and these improvements were difficult to predict without experimental data, assumptions were made based on available literature. IR radiant drying times, when compared to convection, are typically 30% less. This is a result of the fact that radiant energy heats directly and is absorbed at and below the surface, unlike convection heating, that must conduct the heat through the boundary film of air at the clothes surface and rely on wicking of the moisture to the surface. The second area of improvement comes from the NESP. The NESP operation is as follows: 1. Highly charged, micron sized, droplets of water are injected into the dryer exhaust by the Nebulizer. 2. These charged droplets attract water molecules and continue to grow in size, until losing their charge. During this process, latent heat is rejected back into the air stream. 3. The large droplets enter the ESP, where they are recharged and drawn to the ESP wall, to be extracted at the bottom of the ESP. The warm dry air is then recirculated back into the dryer. The proposed technology, at the time of the proposal submission was estimated to have an EF of 4.79. At program completion we have designed, built, tested, integrated and optimized the proposed technologies into a prototype “high efficiency” residential clothes dryer. Testing of the integrated prototype dryer provided insight into the technical effectiveness and economic feasibility of the proposed technologies. The program has the potential of greatly impacting energy savings. The predicted EF of the proposed technology is 4.79, yielding an energy savings of 42% when compared to conventional electric vented dryers. Given there are approximately 84 million dryers in the US consuming ~64 billion kWh per year, a net savings of 27 billion kWh per year or 0.092 quads could be realized. Since the dryer is not vented, make up air from the room is not needed, adding an additional savings of ~1kWh per load, or 23.8 billion kWh per year. In addition, it is envisioned that the proposed ESP, when successful, would potentially find applications in industrial and residential dehumidification.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

On a burning plasma low recycling regime with P DT = 23–26 MW, Q DT = 5–7 in a JET-like tokamak

The recent invention of a continuously flowing liquid lithium system, called 24/7-FLiLi, opens the opportunity to design a plasma pumping divertor which can significantly suppress plasma edge cooling by recycling. The paper describes the expected performance of deuterium–tritium burning plasma with low recycling using a tokamak of JET size, magnetic field and plasma current as an example. So far, only the technological aspects of flowing lithium have been tested on the HT-7 and EAST tokamaks (ASIPP, Hefei, China) with no attempts to create the low recycling regime. The compatibility of 24/7-FLiLi with tokamak plasma was confirmed and some mistakes in the design were revealed, thus, requiring another fabrication approach. Now, with the proper design of the Li system, recycling as low as 0.5 seems to be achievable. The suppression of plasma cooling by recycling in combination with neutral beam injection (NBI) for core plasma fueling by energetic particles automatically leads to ‘the best possible confinement regime’, uniquely compatible with burning plasma. This paper outlines the conceptual details of the 24/7-FLiLi divertor for a JET size tokamak. The main focus is in regard to the physics of the low recycling regime as well as to the expected performance of the burning plasma. In comparison with the results of 1994 on TFTR and 1997 on JET, the projected performance is astonishing: fusion power P DT = 23–26 MW, fusion efficiency Q DT = 5.7 – 6.4, tritium burn up 7.8%–8.7% with modest NBI power P NBI = 4 MW, and energy E NBI = 120 keV. Furthermore, this new regime could resolve the outstanding plasma physics issues related to burning plasma that are unsolvable with the currently dominant approach.

24/7-FLiLi↗

I. Final Report for DOE SBIR Phase I Project DE-SC0013795 Final Report for DOE SBIR Phase I Project DE-SC0013795 Microtron-based Compact, Portable Gamma-Ray Source

Microtron-based Compact, Portable Gamma-Ray Source. The objective of Phase I of this project was to produce a conceptual design of a prototype compact microtron electron accelerator, which could be designed, built, and demonstrated in Phase II of the project. The conceptual design study included an analysis of the parameters of the microtron and its components, and the expected performance of the prototype microtron as a source of x-rays and/or RF neutrons in the MeV energy range. The major components of the microtron are the magnet, the accelerating system, the power system, the vacuum system, the control system, the beam extraction system and the targets to produce x-rays (and/or neutrons). Our objectives for the design of the prototype were for it to be compact, cost-effective, capable of producing high intensity x-ray (an/or neutron) fluxes. In addition, the prototype was to be easily assembled and disassembled so that components could be easily replaced. The main parameters for the prototype are the following: the range of electron kinetic energies, the output power, the RF frequency band (X-band, C-band, or S-Band), the type of injection (Type I or Type II), the magnet type, i.e. permanent magnet, electromagnet, or a hybrid combination of permanent and electromagnet. The results of the Phase I study and analysis for a prototype microtron are the following: The electron energy range can be varied from below 6 MeV to 9 MeV, the optimal frequency range is S-Band (2-4 GHz) RF frequency, Type II injection (described below), and the magnet type is the hybrid version. The prototype version will be capable of producing gamma ray doses of ~1800 R/min-m and neutron fluxes of up to ~6 x 10 10 n/s with appropriate targets. The results of the Phase I study and analysis are provided below. The proposed Phase II plan was to demonstrate the prototype at low beam power. In the subsequent Phase III, high power tests would be performed, and the design of commercial versions of microtrons with various energies, sizes and types would be produced and marketed, including a more compact and more portable 6 MeV battery-powered model that more closely meets the requirements in the original FOA topic description. In the course of the Phase I study, we also identified another microtron version, one that was larger (not compact) and more powerful than that of the Phase II prototype, which could serve as an intense source of photo- neutrons, up to 4 x 10 12 n/s for use in nuclear medicine, short-lived isotope production, or other applications. In addition, it could produce gamma dose rates up to 130 kR/min-m with a heavy metal bremsstrahlung target. The results and specifications of this were submitted to IPAC16 (Reference [12]) the paper is included in Addendum B. Because this version was beyond the scope of the Phase I project, there is no additional description in the Final Report.

43 PARTICLE ACCELERATORS↗

Low-Energy Water Recovery from Subsurface Brines

A novel non-aqueous phase solvent (NAS) desalination process was proposed and developed in this research project. The NAS desalination process uses less energy than thermal processes, doesn’t require any additional chemicals for precipitation, and can be utilized to treat high TDS brine. In this project, our experimental work determined that water solubility changes and selective absorption are the key characteristics of NAS technology for successful desalination. Three NAS desalination mechanisms were investigated: (1) CO 2 switchable, (2) high-temp absorption to low-temp desorption (thermally switchable), and (3) low-temp absorption to high-temp desorption (thermally switchable). Among these mechanisms, thermally switchable (low-temp absorption to high-temp desorption) showed the highest water recovery and relatively high salt rejection. A test procedure for semi-continuous, bench scale NAS desalination process was also developed and used to assess performance under a range of conditions.

20 FOSSIL-FUELED POWER PLANTS↗

Heartbeat: Detecting Malware by Periodic Power Signal Injection and Monitoring

Rootkits and other stealthy malware attempt to conceal their presence on a computer by making changes to the host computer’s operating environment. ORNL’s Heartbeat technology detects these changes, and thus the malware itself. Heartbeat operates by directly monitoring the DC power consumption of the computer while a set of operations, the “heartbeat,” is executed periodically. These operations exercise parts of the operating system that are common targets of malware tampering. The power consumption during these heartbeat events is monitored and then compared to a previously learned baseline, with any significant deviation detected and analyzed. This technology has been tested and validated in a laboratory environment, and ORNL is currently seeking a deployment partner to allow for further in-context development and testing of this technology.

97 MATHEMATICS AND COMPUTING↗

Insights into the physical and chemical properties of a cement-polymer composite developed for geothermal wellbore applications

To isolate injection and production zones from overlying formations and aquifers during geothermal operations, cement is placed in the annulus between well casing and formations. Wellbore cement can fracture due to chemical and physical stress. A polymer-cement (composite) with self-healing properties, stable at high temperatures, was recently developed by our group. Here we present data on the elemental distribution, mineral composition, internal microstructure, and tensile elasticity of this composite and how it compares to cement without polymer (control cement). Entrapped air porosity was similar between control cement (0.44% by volume) and composite (0.22% by volume). Total voids increased with polymer content in the cement (10% and 25% composite), and polymer was found to fill most of these voids. Polymer appears to act as a (cement hydration) retarder increasing the amount of unhydrated silicate minerals in the matrix. Tensile elasticity was improved for composites as compared to control cement, suggesting that the composite materials perform better under mechanical stress. Density-functional calculations reproduce the drop in Young’s modulus by about 60% observed experimentally when polymer is added to the cement. In addition, calculations indicate that the bonding interactions between the cement and polymer remain stable over the range of strain studied.

Rod, Kenton A. (ORCID:0000000318189094)↗

THERMS Technology Commercialization Fund Final Report

The technology commercialization fund assisted with the design and development of an intermediate scale packed be thermal energy storage system. Presented in this final report is the design, testing, and modeling of a 100 kWh th radial packed-bed. Air is used as a heat transfer fluid and 3/8” pea gravel is used as the storage medium. Testing has demonstrated the formation of a thermocline within the packed-bed. An air charging temperature of 450 °C was achieved resulting in a charging power of 26.5 kWh th . The radial packed-bed was charged for 5 hours and discharged for 5 hours. Minimal temperature variation was observed at the bottom, middle, and top axial locations of the radial packed-bed which suggests that buoyancy and hydrodynamics in the injection well had a minimal effect on the uniformity of air flow through the bed during charging and discharging. This indicates that the forced convection in a radial direction is dominating the flow regime compared to the buoyancy. The findings of this study suggest an increased air duct diameter through the air heater will increase the charging temperature and increase air mass flow through the system. Increased mass flow through the packed-bed is hypothesized to shorten the thermocline length. Modeled and measured results are compared, and it is here determined that a more comprehensive CFD model will aid in the understanding of air flow and thermocline evolution within the packed-bed.

25 ENERGY STORAGE↗

Susceptibility of {sup 99m}Tc-Ciprofloxacin for Common Infection Causing Bacterial Strains Isolated from Clinical Samples: an In Vitro and In Vivo Study

{sup 99m}Tc-ciprofloxacin scintigraphy is useful in the detection of gram-positive and gram-negative bacterial infections and also for differentiating the infection from aseptic inflammation. However, due to growing bacterial resistance to antibiotics, the {sup 99m}Tc-ciprofloxacin no longer can be effective in broad-spectrum infection imaging as it is gradually losing specificity. In this study, we are presenting our findings regarding the in vitro and in vivo susceptibility of {sup 99m}Tc-ciprofloxacin for multi-drug-resistant Staphylococcus aurous, Escherichia coli, and Pseudomonas aeruginosa bacterial strains which were isolated from clinical samples. The results of radiosynthesis of {sup 99m}Tc-ciprofloxacin showed more the 95% radiochemical purity and less than 5% radioactive impurities. In vitro {sup 99m}Tc-ciprofloxacin susceptibility test showed that E. coli offered more resistant to {sup 99m}Tc-ciprofloxacin as compared to S. aurous and P. aeruginosa. In vivo study using bacterial infection induced rabbit model also revealed lowest uptake by E. coli lesion. The T/NT values were obtained 1.96 ± 0.15 in the case of E. coli; 2.81 ± 0.51 in the case of S. aurous; and 2.32 ± 0.66 in the case of P. aeruginosa at 4 h post-injection. The SPECT infection imaging of S. aurous, E. coli, and P. aeruginosa bacterial infection induced rabbit models also indicated the clear accumulation in S. aurous and P. aeruginosa lesions while negligible uptake by E. coli lesion further verify the in vitro and in vivo susceptibility profile. On the bases of the results obtained, the {sup 99m}Tc-ciprofloxacin showed selective and poor broad spectrum SPECT infection imaging.

60 APPLIED LIFE SCIENCES↗

A New LMP-Sensitivity-Based Heterogeneous Decomposition for Transmission and Distribution Coordinated Economic Dispatch

Transmission and distribution coordinated economic dispatch (TDCED) will be necessary to settle the problems caused by high penetrations of distributed generators in future grids. An efficient heterogeneous decomposition algorithm (HGD) was proposed to solve the TDCED, but it may diverge occasionally. To overcome this shortcoming, a new HGD (N-HGD) with enhanced convergency is proposed and studied in this paper. Compared with the previous HGD, the N-HGD similarly decomposes the TDCED into transmission ED and distribution ED subproblems, but it considers the sensitivity of the boundary locational marginal price to load injections to enhance convergency and avoid divergence. Two kinds of sensitivity computing methods, M-c and M-p, are studied. M-c is based on a centralized sensitivity equation, executed on the transmission side. M-p is based on a probing mechanism and can be executed distributedly on the distribution side. The reason for the N-HGD's improved convergency is theoretically analyzed, and the optimality is proven. Numerical tests show that N-HGD performs better than the original HGD, as well as a penalty-based modified HGD that needs a careful parametertuning process. Furthermore, compared with M-c, an M-p-based N-HGD is preferable because it has a much lower computational cost and no additional communicational cost.

distribution↗

Geochemical Impact of Acid Spearhead and Slickwater Stimulation on Wolfcamp Shale from the Hydraulic Fracturing Test Site

The Hydraulic Fracturing Test Site 1 (HFTS-1) was a field study performed in the Wolfcamp Formation in the West Texas Permian (Midland) Basin, USA, with a focus on improving the efficiency of hydraulic fracturing. Investigating site-specific rock-fluid geochemical interactions during hydraulic fracturing is an important step to understanding the impact on formation shale porosity, permeability, and long-term shale gas production. During field operations in this region, hydraulic fracturing fluid (HFF) injection usually starts with a concentrated acid spearhead for rapid rock dissolution, followed by the injection of near-neutral pH slickwater containing chemicals and proppants. A multistep sequential injection approach was used to investigate different stages of rock-fluid interactions. The carbonate content in the host rock is important when acid spearhead is considered, as carbonate mineral dissolution is rapid and can result in porosity and permeability changes in the shale matrix. Here, in this study, we designed flow-through experiments using fractured carbonate-rich and clay-rich Wolfcamp shale cores with (1) a short-time acid soaking step and (2) a long-term slickwater flow-through step to simulate the injection method used at HFTS-1. The fluid chemistry was analyzed. A thorough mineralogical progression [e.g., Calcium (Ca) dissolution and iron (Fe) redox progression] in the cores during HFF injection was also characterized and imaged by synchrotron microprobe. Reactive transport modeling was performed based on the experimental setup. The results showed that the acid spearhead is a crucial step in creating a reaction front by mineral dissolution, especially in carbonate-rich shales. A slight layer of ferrihydrite precipitated during the slickwater flow-through period. This study provides insights into potential geochemical impact due to hydraulic fracturing operations in the Permian Basin.

clastic rock↗

Ducted Fuel Injection and Cooled Spray Technologies for Particulate Control in Heavy-Duty Diesel Engines

Heavy-Duty diesel engine manufacturers are continuously in pursuit of simple and low-cost technologies that can reduce emissions. Ducted fuel injection (DFI) and Cooled Spray (CS) technologies are two technologies that continue to show promise for significant particulate emissions reductions. These technologies represent a breakthrough in diesel engine combustion from the potential of nearly sootless diesel combustion. This can provide a significant decrease in harmful PM emissions and may enable further system optimization for reduced NOx emissions and increased efficiency. Combustion vessel experiments and engine demonstrations at Sandia, together with the large bore engine tests performed by Wabtec show that this technology may be applicable to heavy duty diesel engines across a wide range of engine sizes and speeds representing the majority of off-road diesel engines. However, very little is known about the ideal geometry, scaling properties or effectiveness of these technologies over the engine operating map. This project will address those uncertainties through a series of experiments performed in an optical and a metal single-cylinder engine.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Desalination of Impaired Water Using Geothermal Energy

Membrane distillation (MD) and nanofiltration (NF) are explored as a means to provide high quality water for on-site use at the Tuscarora geothermal power plant in northern Nevada. The plant uses a wet cooling tower, but decreasing flow from the wells providing makeup water necessitates exploration for alternative water or alternative cooling sources. Scenarios are explored to extend cooling water by (1) extracting fresh water from the geothermal brine, (2) upgrading the makeup-water quality to allow for increased cycles of concentration in the cooling tower, or (3) recovering water from the cooling tower blowdown. The preliminary cost analysis indicates that applying NF to extract water from the injection brine is the most attractive option of the scenarios examined. This approach may be useful for other plants as well. The estimated cost for the NF treatment of the injection brine ranges from $0.63/m3 to $0.45/m3 and provides a reduction in the current makeup well flows of 35% to 71%. Savings from the reduction in makeup well pumping and chemical treatment do not fully offset the estimated cost of the proposed treatment systems; the site will have to weigh the cost of these water treatment options versus alternatives in light of the diminishing flows from the existing cooling-water wells. Testing is planned to quantify the performance of the proposed NF and MD technologies and help refine the estimated system costs.

15 GEOTHERMAL ENERGY↗

Nondestructive Evaluation (NDE) of Cable Anomalies using Frequency Domain Reflectometry (FDR) and Spread Spectrum Time Domain Reflectometry (SSTDR)

This report presents a comparative assessment of the performance of frequency domain reflectometry (FDR) and spread spectrum time domain reflectometry (SSTDR) in detecting a wide range of electrical cable anomalies. All tests and results reported herein were performed at the PNNL Accelerated and Real-Time Environmental Nodal Assessment (ARENA) cable and motor test bed. The primary objective of this work was to evaluate the effectiveness of SSTDR, a fledgling cable monitoring technique that shows promise for application in online monitoring of energized cable systems, against FDR, an offline technique widely employed in the nuclear power plant (NPP) industry. FDR tests are becoming more widely used in nuclear power plant cable aging management and test programs – particularly for low voltage cables. FDR capabilities for these kinds of tests have been reported by PNNL and others. The FDR test is performed on de-energized cables by connecting the FDR instrument to two of the cable conductors, or one conductor and the shield. A broad band low voltage (< 5 V) chirp is introduced in the cable, and any reflected response is captured in the frequency domain. The captured reflection is then processed by performing an inverse Fourier transform to a time domain response which can then be converted to a distance response based on the cable velocity of propagation (VoP). SSTDR measurements are functionally similar to FDR measurements in that a broad-band voltage signal composed of a square or sine wave modulated pseudo-random sequence of chips (< 5 volts), is injected onto one of the cable conductors. The injected signal will experience partial energy reflection and transmission at each impedance discontinuity along the transmission line. Any reflected response is detected by computing a cross-correlation between the reflected signals and a delayed copy of the incident SSTDR signal. the time delay for the reflected signal to experience the best matched correlation with the incident signal, indicates the travel time for the signal to reach a change in impedance. By knowing this time delay and velocity of propagation (VoP) of the signal, one can compute the physical distance. A big advantage that SSTDR measurements have over other methods is the ability to be connected to energized or live wires (currently up to 1kV) thereby enabling online monitoring of cables. SSTDR has been used successfully in several applications, e.g., aircraft, rail, and photovoltaic systems. In this work FDR and SSTDR cable assessment techniques were used to characterize a variety of cable anomalies and faults including: (1) Presence or absence of a motor; (2) Ground faults and short circuit faults; (3) Moist environments and water ingress faults; (4) Accelerated thermal aging. Both shielded and non-shielded cables were evaluated in this report. Offline measurements were made using FDR and online measurements were made by SSTDR for a range of test scenarios. Based on the results across all cable anomalies evaluated in this study, FDR displayed high sensitivity towards cable condition assessment, while SSTDR showed promise for future application in monitoring NPP cable systems. However, further developments are suggested to improve the resolution and sensitivity of SSTDR towards faults and anomalies in low voltage cables.rt presents a comparative

42 ENGINEERING↗

Degradation mechanisms of 1.3 μm C-doped quantum dot lasers grown on native substrate

Here, the aim of this paper is to analyse the degradation modes of 1.3 μm InAs quantum dot laser diodes (QD LDs) grown by using carbon as a p-type dopant, as an alternative to beryllium. The devices were stressed at high current densities, to favor the onset of excited-state (ES) emission, and to study the related degradation phenomena. The study of QD LDs is of fundamental importance for the photonic integrated circuits (PICs). The investigation is based on two types of stress tests: 1) a current step stress and 2) a constant current stress. With these experiments we demonstrate that a) the current is a determining factor for the onset of the ES during the operation of such devices. b) the onset of ES is responsible for a rapid quenching of the ground state (GS) emission. c) stress induces a significant increase in the threshold current of the devices, that is ascribed to the lowering of the injection efficiency, which in turn can be explained by the easier escape of carriers from quantum dots (QDs) from ES energy levels. d) the contribution of defects on the optical and electrical degradation is also discussed.

42 ENGINEERING↗

Seamless Transition of Critical Infrastructures using Droop Controlled Grid-forming Inverters

Seamless recovery of power to critical infrastructures, after grid failure, is a crucial need arising in scenarios that are increasingly becoming more frequent. Here, this article proposes a seamless transition strategy using a single and unified mode-dependent droop controlled grid-forming inverters. The control strategy achieves the following objectives: 1) regulates the output active and reactive power by the droop-controlled inverters to a desired value while operating in on-grid mode; 2) seamless transition and recovery of power injections into the load after grid failure by inverters that operates in grid-forming mode all the time; 3) requires only a single bit of information on the grid/network status for the mode transition. A framework for assessing the stability of the system and to guide the choice of parameters for controllers is developed using control-oriented modeling. A controller hardware-in-the-loop-based real-time simulation study on a test system based on the realistic electrical network of a commercial-scale medical center is conducted for initial prototyping of the control strategy. A hardware experiment is conducted with two 3 - $\phi$, 480 -V, 125 -kVA grid-forming inverters, a 3 - $\phi$, 480 -V, 270 -kVA grid simulator, a physical grid switch, and a physical load bank. The experimental data establishes the effectiveness of the always grid-forming operation and control of inverters in meeting power delivery objectives when on-grid and off-grid under various kinds of loads and scenarios while minimizing transients during transitions. Furthermore, performance comparison with existing strategies showcases the advantage of the proposed strategy.

24 POWER TRANSMISSION AND DISTRIBUTION↗

TU-F-CAMPUS-J-02: Evaluation of Textural Feature Extraction for Radiotherapy Response Assessment of Early Stage Breast Cancer Patients Using Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI

Purpose: To investigate the feasibility of using classic textural feature extraction in radiotherapy response assessment, we studied a unique cohort of early stage breast cancer patients with paired pre - and post-radiation Diffusion Weighted MRI (DWI-MRI) and Dynamic Contrast Enhanced MRI (DCE-MRI). Methods: 15 female patients from our prospective phase I trial evaluating preoperative radiotherapy were included in this retrospective study. Each patient received a single-fraction radiation treatment, and DWI and DCE scans were conducted before and after the radiotherapy. DWI scans were acquired using a spin-echo EPI sequence with diffusion weighting factors of b = 0 and b = 500 mm{sup 2} /s, and the apparent diffusion coefficient (ADC) maps were calculated. DCE-MRI scans were acquired using a T{sub 1}-weighted 3D SPGR sequence with a temporal resolution of about 1 minute. The contrast agent (CA) was intravenously injected with a 0.1 mmol/kg bodyweight dose at 2 ml/s. Two parameters, volume transfer constant (K{sup trans} ) and k{sub ep} were analyzed using the two-compartment Tofts kinetic model. For DCE parametric maps and ADC maps, 33 textural features were generated from the clinical target volume (CTV) in a 3D fashion using the classic gray level co-occurrence matrix (GLCOM) and gray level run length matrix (GLRLM). Wilcoxon signed-rank test was used to determine the significance of each texture feature’s change after the radiotherapy. The significance was set to 0.05 with Bonferroni correction. Results: For ADC maps calculated from DWI-MRI, 24 out of 33 CTV features changed significantly after the radiotherapy. For DCE-MRI pharmacokinetic parameters, all 33 CTV features of K{sup trans} and 33 features of k{sub ep} changed significantly. Conclusion: Initial results indicate that those significantly changed classic texture features are sensitive to radiation-induced changes and can be used for assessment of radiotherapy response in breast cancer.

60 APPLIED LIFE SCIENCES↗

Demonstration of Magnetron as an Alternative RF Source for SRF Accelerators

Magnetron has been considered as alternate high-efficiency, low-cost RF sources for linacs and storage rings [1] for national labs and industrial applications. After the demonstration of magnetrons power to drive and combine for a radio frequency cavity at 2450 MHz in CW mode, we have used trim coils adding to a water-cooled magnetron and amplitude modulation feedback to further suppress the side-band noise to -46.7 dBc level. We also demonstrated the phase-locking to an industrial grade cooking magnetron transmitter at 915 MHz with a 75 kW CW power delivered to a water load by using a -26.6 dBc injection signal [2]. The sideband noise from the 3-Phase SCRs DC power supply can be reduced to -16.2 dBc level. Further noise reduction and their power combining scheme using magic-tee and cavity type combiners for higher power application (2x75kW) are to be presented. We intent to use one power station to drive the normal conducting and superconducting RF cavities for the inductrial linac. We also going to demonstarte a vertical SRF cavity test with a high input coupling Q using a 2.45GHz magnetron and comparing with a baseline test result using a solid state amplifier.

Wang, H.↗

Closing the Loop Between In Situ Stress Complexity and EGS Fracture Complexity (Quarterly Research Performance Progress Report: Q3Y3)

As part of Task 1, we have started by testing our modeling capabilities by reproducing isothermal DFIT simulations presented in the literature. To start, we have been working towards adjusting numerical parameters to reproduce DFIT tests with different fracture geometries. Then, we have focused modeling the DFIT conducted at well 58-32 (cycle 4 in zone 2). Specifically, we have carefully analyzed the influence of the aperture-contact stress relationship and investigated how two different laws affect model results. We have also introduced thermal effects in the model and rerun the simulations to estimate the effect of cooling on the DFIT response. Due to the small amount of fluid injected during a DFIT, thermal effects seem to be moderate.

15 GEOTHERMAL ENERGY↗