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The NASA Open Science Data Repository: Biomedical Data, Analysis Tools, and Informatic Collaborations

Increased biomedical risks and challenges associated with deep space missions require knowledge discovery, health countermeasures, and biomedical support capabilities. Maximally open-access and reusable data is needed by developers, scientists, and engineers to develop these systems. The NASA Open Science Data Repository (OSDR) is a maximally open access and FAIR database (ie., findable, accessible, interoperable, and reusable), and meets various scientific, technical, and operational needs. It offers users and submitters the ability to upload, download, search, share, analyze, cite, and visualize data across ‘omics, physiological, phenotypic, payload, hardware, behavioral, bioimaging, video, and environmental monitoring telemetry datasets. OSDR is an expanded database, based upon the successes of NASA GeneLab. OSDR has >460 studies with datasets covering model organisms to non-NASA human astronauts. There are ~12 datasets from the Inspiration 4 (I4) mission, spanning metagenomics, comprehensive metabolic panels, clonal hematopoiesis, spatial transcriptomics, proteomics, and cytokine panels. In the interest of data privacy, two I4 datasets with raw files relating to the epitranscriptome, and a new request feature is live in OSDR (with a backend review process established) developed from industry norms. OSDR is collecting and curating biomedical human data from a new sub-orbital research flight and is open to more space life science/biomedical submissions from the international and commercial sectors. OSDR also recently began a collaboration with the European Space Agency (ESA) to collect and curate >200 terabytes of human and model organism data. The OSDR submission portal is designed to ingest and curate ~25 ‘omics and ~50 physiological-phenotypic-imaging assay data types. Tools available for OSDR users include: 1) an Environmental Data Application to compare radiation, CO2, relative humidity, temperature, and other telemetry across missions and subjects, 2) the RadLab database, a collaboration between NASA, ESA, the German and Italian Space Agencies, and the Bulgarian Academy of Sciences, and 3) a Multi-study visualization tool which enables users to look across and combine ‘omics datasets. There are ~600 volunteer OSDR Analysis Working Group (AWG) members providing feedback on scientific data/metadata standards and collaborating to mine-reuse OSDR in research. OSDR/GeneLab has enabled ~60 publications reusing data as of October 2023.

space biology↗

The NASA Radiation Interuniversity Science and Engineering(RaISE) Project: A Model for Inter-collaboration and Distance Learning in Radiation Physics and Nuclear Engineering

This viewgraph document reviews the Radiation Interuniversity Science and Engineering (RaISE) Project, which is a project that has as its goals strengthening and furthering the curriculum in radiation sciences at two Historically Black Colleges and Universities (HBCU), Prairie View A&M University and Texas Southern University. Those were chosen in part because of the proximity to NASA Johnson Space Center, a lead center for the Space Radiation Health Program. The presentation reviews the courses that have been developed, both in-class, and on-line.

Denkins, Pamela S.↗

BOREAS HYD-1 Soil Hydraulic Properties

The Boreal Ecosystem-Atmosphere Study (BOREAS) Hydrology (HYD)-1 team coordinated a program of data collection to measure and monitor soil properties in collaboration with other science team measurement needs. This data set contains soil hydraulic properties determined at the Northern Study Area (NSA) and Southern Study Area (SSA) flux tower sites based on analysis of in situ tension infiltrometer tests and laboratory-determined water retention from soil cores collected during the 1994-95 field campaigns. Results from this analysis are saturated hydraulic conductivity, and fitting parameters for the van Genuchten-Mualem soil hydraulic conductivity and water retention function at flux tower sites. The data are contained in tabular ASCII files. The HYD-01 soil hydraulic properties data are available from the Earth Observing System Data and Information System (EOSDIS) Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC). The data files are available on a CD-ROM (see document number 20010000884).

Hall, Forrest G.↗

The Athena Raman Spectrometer

Raman spectroscopy provides a powerful tool for in situ mineralogy, petrology, and detection of water and carbon. The Athena Raman spectrometer is a microbeam instrument intended for close-up analyses of targets (rock or soils) selected by the Athena Pancam and Mini-TES. It will take 100 Raman spectra along a linear traverse of approximately one centimeter (point-counting procedure) in one to four hours during the Mars' night. From these spectra, the following information about the target will extracted: (1) the identities of major, minor, and trace mineral phases, organic species (e.g., PAH or kerogen-like polymers), reduced inorganic carbon, and water-bearing phases; (2) chemical features (e.g. Mg/Fe ratio) of major minerals; and (3) rock textural features (e.g., mineral clusters, amygdular filling and veins). Part of the Athena payload, the miniaturized Raman spectrometer has been under development in a highly interactive collaboration of a science team at Washington University and the University of Alabama at Birmingham, and an engineering team at the Jet Propulsion Laboratory. The development has completed the brassboard stage and has produced the design for the engineering model.

Wang, Alian↗

Numerical Simulations and Diagnostic Studies of Meteorological Conditions During PEM-Tropics B

Provides a final report on the work accomplished by several meteorological scientists under a NASA grant in conjunction with the DC-8 component of Pacific Exploratory Mission (PEM)-Tropics B. The responsibilities of the principal investigator included collaboration with the Science Team on flight planning, presentation of forecasts, and the preparation of map discussions for each flight. In a published manuscript, the principal investigator summarized the meteorological conditions during PEM-TB which included mean flow patterns, subtropical anticyclones, the South Pacific Convergence Zone (SPCZ), and the Intertropical Convergence Zone (ITCZ). Methodologies used included streamlines, ten day backward trajectories, thermodynamic soundings, and satellite imagery. Other interests included air sampling for the purpose of determining pollution levels.

Fuelberg, Henry E.↗

Interactive Learning During Solar Maximum

The goal of this project is to develop and distribute e-educational material for space science during times of solar activity that emphasizes underlying basic science principles of solar disturbances and their effects on Earth. This includes materials such as simulations, animations, group projects and other on-line materials to be used by students either in high school or at the introductory college level. The on-line delivery tool originally intended to be used is known as Interactive Multimedia Education at a Distance (IMED), which is a web-based software system used at UCLA for interactive distance learning. IMED is a password controlled system that allows students to access text, images, bulletin boards, chat rooms, animation, simulations and individual student web sites to study science and to collaborate on group projects.

Ashour-Abdalla, Maha↗

Space-based Science Operations Grid Prototype

Grid technology is the up and coming technology that is enabling widely disparate services to be offered to users that is very economical, easy to use and not available on a wide basis. Under the Grid concept disparate organizations generally defined as "virtual organizations" can share services i.e. sharing discipline specific computer applications, required to accomplish the specific scientific and engineering organizational goals and objectives. Grids are emerging as the new technology of the future. Grid technology has been enabled by the evolution of increasingly high speed networking. Without the evolution of high speed networking Grid technology would not have emerged. NASA/Marshall Space Flight Center's (MSFC) Flight Projects Directorate, Ground Systems Department is developing a Space-based Science Operations Grid prototype to provide to scientists and engineers the tools necessary to operate space-based science payloads/experiments and for scientists to conduct public and educational outreach. In addition Grid technology can provide new services not currently available to users. These services include mission voice and video, application sharing, telemetry management and display, payload and experiment commanding, data mining, high order data processing, discipline specific application sharing and data storage, all from a single grid portal. The Prototype will provide most of these services in a first step demonstration of integrated Grid and space-based science operations technologies. It will initially be based on the International Space Station science operational services located at the Payload Operations Integration Center at MSFC, but can be applied to many NASA projects including free flying satellites and future projects. The Prototype will use the Internet2 Abilene Research and Education Network that is currently a 10 Gb backbone network to reach the University of Alabama at Huntsville and several other, as yet unidentified, Space Station based science experimenters. There is an international aspect to the Grid involving the America's Pathway (AMPath) network, the Chilean REUNA Research and Education Network and the University of Chile in Santiago that will further demonstrate how extensive these services can be used. From the user's perspective, the Prototype will provide a single interface and logon to these varied services without the complexity of knowing the where's and how's of each service. There is a separate and deliberate emphasis on security. Security will be addressed by specifically outlining the different approaches and tools used. Grid technology, unlike the Internet, is being designed with security in mind. In addition we will show the locations, configurations and network paths associated with each service and virtual organization. We will discuss the separate virtual organizations that we define for the varied user communities. These will include certain, as yet undetermined, space-based science functions and/or processes and will include specific virtual organizations required for public and educational outreach and science and engineering collaboration. We will also discuss the Grid Prototype performance and the potential for further Grid applications both space-based and ground based projects and processes. In this paper and presentation we will detail each service and how they are integrated using Grid

Bradford, Robert N.↗

Invasive Species Forecasting System: A Decision Support Tool for the U.S. Geological Survey: FY 2005 Benchmarking Report v.1.6

The National Institute of Invasive Species Science (NIISS), through collaboration with NASA's Goddard Space Flight Center (GSFC), recently began incorporating NASA observations and predictive modeling tools to fulfill its mission. These enhancements, labeled collectively as the Invasive Species Forecasting System (ISFS), are now in place in the NIISS in their initial state (V1.0). The ISFS is the primary decision support tool of the NIISS for the management and control of invasive species on Department of Interior and adjacent lands. The ISFS is the backbone for a unique information services line-of-business for the NIISS, and it provides the means for delivering advanced decision support capabilities to a wide range of management applications. This report describes the operational characteristics of the ISFS, a decision support tool of the United States Geological Survey (USGS). Recent enhancements to the performance of the ISFS, attained through the integration of observations, models, and systems engineering from the NASA are benchmarked; i.e., described quantitatively and evaluated in relation to the performance of the USGS system before incorporation of the NASA enhancements. This report benchmarks Version 1.0 of the ISFS.

Stohlgren, Tom↗

The International Space Station Urine Monitoring System (UMS)

A device capable of making in-flight volume measurements of single void urine samples, the Urine Monitoring System (UMS), was developed and flown on seven U.S. Space Shuttle missions. This device provided volume data for each urine void from multiple crewmembers and allowed samples of each to be taken and returned to Earth for post-flight analysis. There were a number of design flaws in the original instrument including the presence of liquid carry-over producing invalid "actual" micturition volumes and cross-contamination between successive users from residual urine in "dead" spots". Additionally, high or low volume voids could not be accurately measured, the on-orbit calibration and nominal use sequence was time intensive, and the unit had to be returned and disassembled to retrieve the volume data. These problems have been resolved in a new version, the International Space Station (ISS) UMS, that has been designed to provide real-time in-flight volume data with accuracy and precision equivalent to measurements made on Earth and the ability to provide urine samples that are unadulterated by the device. Originally conceived to be interfaced with a U.S.-built Waste Collection System (WCS), the unit now has been modified to interface with the Russian-supplied Sanitary Hygiene Device (ASY). The ISS UMS provides significant advantages over the current method of collecting urine samples into Urine Collection Devices (UCDs), from which samples are removed and returned to Earth for analyses. A significant future advantage of the UMS is that it can provide an interface to analytical instrumentation that will allow real-time measurement of urine bioanalytes allowing monitoring of crewmember health status during flight and the ability to provide medical interventions based on the results of these measurements. Currently, the ISS UMS is scheduled to launch along with Node-3 on STS-130 (20A) in December 2009. UMS will be installed and scientific/functional verification completed prior to placing the instrument into operation. Samples collected during the verification sequence will be returned for analyses on STS-131 (19A) currently scheduled for launch in March 2010. The presence of a UMS on ISS will provide the capability to conduct additional collaborative human life science investigations among the ISS International Partners.

Feeback, Daniel L.↗

A Vision for the Exploration of Mars: Robotic Precursors Followed by Humans to Mars Orbit in 2033

The reformulation of the Mars program gives NASA a rare opportunity to deliver a credible vision in which humans, robots, and advancements in information technology combine to open the deep space frontier to Mars. There is a broad challenge in the reformulation of the Mars exploration program that truly sets the stage for: 'a strategic collaboration between the Science Mission Directorate (SMD), the Human Exploration and Operations Mission Directorate (HEOMD) and the Office of the Chief Technologist, for the next several decades of exploring Mars'.Any strategy that links all three challenge areas listed into a true long term strategic program necessitates discussion. NASA's SMD and HEOMD should accept the President's challenge and vision by developing an integrated program that will enable a human expedition to Mars orbit in 2033 with the goal of returning samples suitable for addressing the question of whether life exists or ever existed on Mars

Sellers, Piers J.↗

Optimizing Vetoes for Gravitational-wave Transient Searches

Interferometric gravitational-wave detectors like LIGO, GEO600 and Virgo record a surplus of information above and beyond possible gravitational-wave events. These auxiliary channels capture information about the state of the detector and its surroundings which can be used to infer potential terrestrial noise sources of some gravitational-wave-like events. We present an algorithm addressing the ordering (or equivalently optimizing) of such information from auxiliary systems in gravitational-wave detectors to establish veto conditions in searches for gravitational-wave transients. The procedure was used to identify vetoes for searches for unmodelled transients by the LIGO and Virgo collaborations during their science runs from 2005 through 2007. In this work we present the details of the algorithm; we also use a limited amount of data from LIGO's past runs in order to examine the method, compare it with other methods, and identify its potential to characterize the instruments themselves. We examine the dependence of Receiver Operating Characteristic curves on the various parameters of the veto method and the implementation on real data. We find that the method robustly determines important auxiliary channels, ordering them by the apparent strength of their correlations to the gravitational-wave channel. This list can substantially reduce the background of noise events in the gravitational-wave data. In this way it can identify the source of glitches in the detector as well as assist in establishing confidence in the detection of gravitational-wave transients.

Transient↗

NASA's Astromaterials Database: Enabling Research Through Increased Access to Sample Data, Metadata and Imagery

The Astromaterials Acquisition & Curation Office at NASA's Johnson Space Center (JSC) is the designated facility for curating all of NASA's extraterrestrial samples. Today, the suite of collections includes the lunar samples from the Apollo missions, cosmic dust particles falling into the Earth's atmosphere, meteorites collected in Antarctica, comet and interstellar dust particles from the Stardust mission, asteroid particles from Japan's Hayabusa mission, solar wind atoms collected during the Genesis mission, and space‐exposed hardware from several missions. To support planetary science research on these samples, JSC's Astromaterials Curation Office hosts NASA's Astromaterials Curation digital repository and data access portal [http://curator.jsc.nasa.gov/], providing descriptions of the missions and collections, and critical information about each individual sample. Our office is designing and implementing several informatics initiatives to better serve the planetary research community. First, we are re‐hosting the basic database framework by consolidating legacy databases for individual collections and providing a uniform access point for information (descriptions, imagery, classification) on all of our samples. Second, we continue to upgrade and host digital compendia that summarize and highlight published findings on the samples (e.g., lunar samples, meteorites from Mars). We host high resolution imagery of samples as it becomes available, including newly scanned images of historical prints from the Apollo missions. Finally we are creating plans to collect and provide new data, including 3D imagery, point cloud data, micro CT data, and external links to other data sets on selected samples. Together, these individual efforts will provide unprecedented digital access to NASA's Astromaterials, enabling preservation of the samples through more specific and targeted requests, and supporting new planetary science research and collaborations on the samples.

Evans, Cindy↗

Ka-band High-Rate Downlink System for the NISAR Mission

This paper provides a description and analyses of the high-rate Ka-band telecom system for the upcoming NISAR (NASA-ISRO Synthetic Aperture Radar) mission. NISAR is a collaborative Earth-Science mission between National Aeronautics and Space Administration (NASA) and Indian Space Research Organization (ISRO), which features an L-band SAR instrument and an S-band SAR instrument. The simultaneous dual-frequency radar system at peak rates will produce data at gigabit-per-second speeds, which drives the data-volume requirements. The key driving requirement for the payload communication subsystem is to provide a minimum of 26 Terabits per day of radar science data to the ground. The high-rate transmitter on the flight system is a software-defined radio developed at the Jet Propulsion Laboratory (JPL), based on the Universal Space Transponder platform, providing an offset quadrature phase shift key modulated waveform with Low-Density Parity-Check encoding of the data transfer frames. Two transmitters used in a dual-polarization configuration with each transmitter providing two giga-symbols per second (Gsps) of coded data provides an aggregate rate of four Gsps. In this system, only one watt of signal power is necessary on each polarization to overcome propagation losses and achieve a successful RF link. Several Near Earth Network (NEN) ground station sites (Alaska in the United States, Svalbard in Norway, and Punta Arenas in Chile) are baselined for the space-to-Earth communications link. Each ground station will also feature multiple upgrades to support NISAR’s transmission starting with new Ka-band antennas, wideband downconverters and high-rate receivers. In addition, a baseband data processor called Data Acquisition Processor and Handling Network Environment (DAPHNE), newly developed by the NEN, provides data storage and connectivity to backhaul networks. With NISAR’s large quantities of data (over 3.5 Petabytes over the mission), the processing of science data will be primarily performed on a cloud system to reduce the overall cost to the mission. The system described herein will be the first operational use of Gsps-class downlink rates on an Earth-Science mission.

Dissanayake, Asoka↗

CloudSat - From the A-Train to the C-Train

The CloudSat satellite was launched from Vandenberg Air Force Base, in California, on April 28, 2006. It was launched with the CALIPSO satellite, a joint mission between the National Aeronautics and Space Administration (NASA) and the Centre National D'Etudes Spatiales (CNES). CloudSat and CALIPSO were designed to fly in formation with each other, to combine their complimentary scientific measurements. The two missions were maneuvered into the Earth Science Afternoon Constellation (A-Train) shortly after launch and have flown in formation together since then. Originally designed to fly for 22 months, the CloudSat satellite has far exceeded expectations. Inflight anomalies on CloudSat necessitated changes to both the daily concept of operations and formation flying operations with CALIPSO. In 2011, a severe battery anomaly restricted CloudSat science data collection and maneuverability to the sunlit portions of the orbit. In 2017, CloudSat suffered a reaction wheel failure, triggering the criteria established to exit the A-Train. CloudSat successfully exited the A-Train in early 2018, suspending formation flying and joint science observations with CALIPSO. The joint CloudSat/CALIPSO science team continued collaboration with discussions focused on resuming joint observations. As both satellites were aging and CALIPSO was nearing the exhaustion of satellite propellant, the decision was made to lower CloudSat to the CALIPSO graveyard orbit, to be joined by CALIPSO as soon as feasible. With NASA’s approval, CloudSat was maneuvered to the lower orbit over the course of several months in mid-2018. Once CloudSat was in place, and with approval from CNES, CALIPSO began the delicate dance of lowering their orbit and re-aligning the satellite ground tracks. CloudSat and CALIPSO resumed formation flying in the newly dubbed C-Train (CloudSat and CALIPSO) orbit in the Fall of 2018. The ingenuity of the CloudSat and CALIPSO teams made the concept of the C-Train a reality. This paper will discuss the decision processes and the operational challenges the CloudSat flight team faced while designing and implementing the C-Train.

Witkowski, M.M.↗

ICARTT File Format Enhancements: Supporting FAIRness of Airborne and Field Campaign Data

The ICARTT (International Consortium for Atmospheric Research on Transport and Transformation) standards were developed to fulfill data management needs for the ICARTT campaign in 2004. The ICARTT file format is text-based and composed of a header with important data description information and the data section. The ICARTT format, built on the NASA Ames and GTE data formats, was created to facilitate data exchange and promote collaborations among the science teams for achieving the ICARTT campaign goals. Due to the success of the ICARTT campaign, the ICARTT file format was exposed to a broad range of airborne researchers and was adopted for use in many other field campaigns sponsored by NASA and other partner agencies. The ICARTT format standards became a NASA standard in 2010 and was amended in January 2017 providing many enhancements, including the requirement for variable standard names. Primarily designed for airborne field studies, ICARTT has been further utilized for ground-based studies. The ICARTT format can host metadata that is critical for proper use of the data, especially for in-situ measurements. However, the information that needs to be included is often in free text, meaning the information are human readable, but not machine interpretable. Furthermore, the amount and type of information provided can vary substantially between principal investigators and campaigns. To support interoperability and FAIR principles, further enhancements to the ICARTT standards are recommended. Possible recommendations include standardizing timestamps for easier data comparisons and analysis; potential use of controlled and consistent vocabulary for variable short name and certain common metadata elements; and providing guidance on variable measurement units and how they are reported.

Megan Buzanowicz↗

ICARTT File Format Enhancements: Supporting FAIRness and Data Discovery of Suborbital Campaign Data

Suborbital campaigns aim to accomplish a wide variety of goals and can include a variety of platforms, instruments, and parameters measured. In 2004, the ICARTT (International Consortium for Atmospheric Research on Transport and Transformation) standards were developed to fulfill data management needs for the ICARTT campaign. The ICARTT file format is text-based and composed of a header with important data description information and the data section. Built on the NASA Ames and GTE data formats, the ICARTT format was created to facilitate data exchange and promote collaborations among the science teams for achieving the ICARTT campaign goals. Due to its success and adaptation for use in many other field campaigns, the ICARTT file format became a NASA standard in 2010 and was amended in January 2017. These changes provided many enhancements, including the requirement for variable standard names. Primarily designed for airborne field studies, ICARTT has been further utilized for ground-based studies. NASA has made a commitment to build an inclusive open science community over the next decade. Open-source science strives to make publicly funded scientific research transparent, inclusive, accessible, and reproducible. The ICARTT format can host metadata that is critical for proper use of the data, particularly for in-situ measurements, and can enhance data discovery and accessibility. However, the required fields are often free text, meaning that the information is human readable, but not machine interpretable. Furthermore, the amount and type of information provided can vary significantly between principal investigators and campaigns. To support FAIR principles and interoperability, enhancements to the ICARTT standards are recommended. Possible recommendations include potential use of controlled and consistent vocabulary for variable standard name and certain common metadata elements; standardizing timestamps for easier data comparisons and analysis; and providing guidance on variable measurement units and how they are reported. Enhancing ICARTT metadata can further streamline the process to make suborbital data more readily available to the data user and improve variable-level metadata. Providing more variable-level metadata can enhance data searching and discovery, supporting NASA’s Open-Source Science Initiative (OSSI).

Megan Buzanowicz↗

Dust Characterization Needs for Dust Mitigation

Unknowns remain regarding several lunar dust characteristics, and the lunar dust mitigation community, in collaboration with the science community, is compiling a list of lunar dust characterization needs. It is expected, through the course of currently planned or future lunar surface mission instrumentation, lab experiments, or analysis, that some of these unknowns will be characterized. This list is derived from several sources including findings from the 2020 publication “The Impact of Lunar Dust on Human Exploration”, NASA-STD-1008, SLS-SPEC-159 DSNE, and known gaps identified within NASA programs and projects. The goal of this information collection process is to create a list of dust characterization needs based on scientific and engineering knowledge gaps that will aid in the design and survival of designed and future systems, and address the challenges related to defining the lunar environment and mitigating lunar dust effects on systems and operations. Examples of dust properties and characterization needs include detailed examination of the finest fraction of lunar regolith as it varies by surface location, understanding dust transfer within natural and induced environments, determination of the effects of the lunar plasma environment with regards to materials and hardware, understand the triboelectric charging effects for activities and hardware in contact with the regolith, including grain to grain electrostatic interactions, and material adhesive properties.

dust mitigation↗

A User-Focused Renovation of CERES Metadata

Production software and public data products for Clouds and the Earth’s Radiant Energy System (CERES) continue to evolve as the project extends its climate data record. The data management team for CERES is currently undertaking major renovations of both code and data products, the latter of which is, of course, in service of improving user experience. A major mode of CERES’ data product improvement is in renovating products’ metadata. Metadata standards have evolved since CERES began producing its data products in 2000. In its twentieth year, CERES essentially asked the question: how would the project design its data products if it could start all over again? With forthcoming editions, this rebirth will be realized. CERES has redesigned its metadata standards to best position itself for data discoverability. The project has used the latest standards being developed in NASA’s Earth Science Data and Information Systems (ESDIS) Project’s Unified Metadata Model (UMM) documentation; collaborated with the Atmospheric Science Data Center (ASDC) to ensure compliance with Common Metadata Repository compatibility, and continued compliance with Climate and Forecast (CF) Conventions. In doing so, the team created its own, internal document for proper metadata creation and metadata verification software that is deployed prior to all code deliveries. This presentation will discuss this redesign process, as well as needs met and those that are still outstanding in the search for an improved user experience with CERES data products.

Kathleen Dejwakh↗