Stem Cells Combined With Platelet-rich Plasma Effectively Treat Corticosteroid-induced Osteonecrosis of the Hip: A Prospective Study
Abstract not provided
Houdek, Matthew T.↗
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A Section 106 Evaluation of the Mercury Bowling Alley, Area 23, Nevada National Security Site, Nye County, Nevada, with Photographic Documentation Addendums
The National Nuclear Security Administration Nevada Field Office (NNSA/NFO) anticipates demolition of the Mercury Bowling Alley (Building 23-517) on the Nevada National Security Site (NNSS) in Nye County, Nevada (Figure 1). This survey was prompted by plans to construct new facilities at the Bowling Alley location to support NNSS’s changing role in national security. The Bowling Alley has been largely vacant since the mid-1990s following the end of nuclear testing at what was then the Nevada Test Site (NTS). The building is suffering rapid decay. An Area of Potential Effects (APE) of 4.5 acres was surveyed, resulting in recording and evaluation of the Bowling Alley (SHPO Resource Number B14451) and one associated resource (AR1). The APE is located in Section 11 T15S R53E MDBM (projected) at the principal NNSS base of Mercury in Area 23. In 2010, the NTS name was changed to the NNSS, and will be referred to as such throughout this report. Fieldwork and report preparation were done by Desert Research Institute (DRI) cultural resources staff. Architectural descriptions and portions of this report specific to the architecture of the Bowling Alley were completed by Ron Reno, Ph.D., RPA who meets Secretary of the Interior’s Professional Qualifications Standards for Architectural Historian. Administration of the project was by Colleen M. Beck, Ph.D. Historical background regarding Mercury and the NNSS was developed by Maureen King. Beck photographed the building and its environs. Copies of the building form and report are on file in the Nevada Cultural Resources Inventory System at the Nevada State Office of Historic Preservation (SHPO); DRI, Las Vegas; and in the NNSA/NFO curation facility, Las Vegas.
54 ENVIRONMENTAL SCIENCES↗
Bayesian projection pursuit regression
In projection pursuit regression (PPR), a univariate response variable is approximated by the sum of $M$ “ridge functions,” which are flexible functions of one-dimensional projections of a multivariate input variable. Traditionally, optimization routines are used to choose the projection directions and ridge functions via a sequential algorithm, and $M$ is typically chosen via cross-validation. Here, we introduce a novel Bayesian version of PPR, which has the benefit of accurate uncertainty quantification. To infer appropriate projection directions and ridge functions, we apply novel adaptations of methods used for the single ridge function case ($M$=1), called the Bayesian Single Index Model; and use a Reversible Jump Markov chain Monte Carlo algorithm to infer the number of ridge functions $M$. We evaluate the predictive ability of our model in 20 simulated scenarios and for 23 real datasets, in a bake-off against an array of state-of-the-art regression methods. Finally, we generalize this methodology and demonstrate the ability to accurately model multivariate response variables. Its effective performance indicates that Bayesian Projection Pursuit Regression is a valuable addition to the existing regression toolbox.
97 MATHEMATICS AND COMPUTING↗
Experimental and theoretical investigations in two-dimensional transonic flow.
Experimental and theoretical results are presented from a study of the flow over a family of transonically scaled circular-arc bodies mounted in a solid-wall wind tunnel. Data are presented for Reynolds numbers between 30,000 and 3,600,000, based on chord. The high Reynolds number results are compared with computations based on inviscid theory, and are used to investigate transonic similarity and the behavior of the flow near choking. The results at low Reynolds number are used to demonstrate the effect of viscosity on the overall flowfield, and comparisons are made with existing laminar viscous/inviscid interaction theory.
Collins, D. J.↗
Apollo Soyuz Test Project Weights and Mass Properties Operational Management System
The Apollo Soyuz Test Project (ASTP) Weights and Mass Properties Operational Management System was established to assure a timely and authoritative method of acquiring, controlling, generating, and disseminating an official set of vehicle weights and mass properties data. This paper provides an overview of the system and its interaction with the various aspects of vehicle and component design, mission planning, hardware and software simulations and verification, and real-time mission support activities. The effect of vehicle configuration, design maturity, and consumables updates is discussed in the context of weight control.
Collins, M. A., Jr.↗
Implementation of a fast digital optical matrix-vector multiplier using a holographic look-up table and residue arithmetic
The design and implementation of a digital (numerical) optical matrix-vector multiplier are presented. A Hughes liquid crystal light valve, the residue arithmetic representation, and a holographic optical memory are used to construct position coded optical look-up tables. All operations are performed in effectively one light valve response time with a potential for a high information density.
Habiby, Sarry F.↗
Thermodynamic regulation of ocean warming by cirrus clouds deduced from observations of the 1987 El Nino
Observations made during the 1987 El Nino show that in the upper range of sea surface temperatures, the greenhouse effect increases with surface temperature at a rate which exceeds the rate at which radiation is being emitted from the surface. In response to this 'super greenhouse effect', highly reflective cirrus clouds are produced which act like a thermostat, shielding the ocean from solar radiation. The regulatory effect of these cirrus clouds may limit sea surface temperatures to less than 305 K.
Ramanathan, V.↗
In-suit CO2 Washout Test System (ICWTS) for CO2 Washout Verification in Spacesuits
Since the time of Mercury, Gemini, and Apollo, NASA has been performing CO 2 washout verification of spacesuits with Human in the Loop (HITL) test methods. Classically, the only instrumentation both with the accuracy and response time necessary was that of external mass spectrometers or medical gas analyzers fed by a long capillary line from the oro-nasal region within the suit. The helmet CO 2 washout configuration including the challenges posed by variation of a suited human subject frequently created difficulty in capturing adequate breath by breath data. For example, a nasal cannula could be worn with reasonable comfort however it posed the following challenges: (1) impeded the test subject’s ability to do a proper Valsalva maneuver; (2) frequently provided a corrupted waveform with relative movement; (3) precluded the ability to evaluate the Flow Weighted Average (FWA) at subject interface. A mouthpiece could be used in lieu of a cannula but posed challenges as well: (1) created potential disturbances of the flow field; (2) precluded the test subject from speaking during usage; and (3) presented comfort issues limiting the duration of test points. These challenges made it impractical to use a mouthpiece for anything other than short lab ambient environment tests. Technology development and NASA investment have afforded new capabilities to address some of these measurements providing improved data collection and are implemented in the In-suit CO 2 Washout Test System (ICWTS) which provides suit inlet/outlet pressure, temperature, relative humidity, partial pressure of oxygen, partial pressure of CO 2 , and flow measurement coupled with the acquisition of the inspired PPCO 2 including the ability for FWA measurement. This test system, coupled with use of the In-suit Respiration Mannequin Assembly (IRMA) and Computational Fluid Dynamics (CFD) combine to provide a full picture of the in-suit oro-nasal flow field and effectiveness of CO 2 washout in a spacesuit design.
Colin Campbell↗
In-suit CO 2 Washout Test System (ICWTS) for CO 2 Washout Verification in Spacesuits
Since the time of Mercury, Gemini, and Apollo, NASA has been performing CO 2 washout verification of spacesuits with Human in the Loop (HITL) test methods. Classically, the only instrumentation both with the accuracy and response time necessary was that of external mass spectrometers or medical gas analyzers fed by a long capillary line from the oro-nasal region within the suit. The helmet CO 2 washout configuration including the challenges posed by variation of a suited human subject frequently created difficulty in capturing adequate breath by breath data. For example, a nasal cannula could be worn with reasonable comfort however it posed the following challenges: (1) impeded the test subject’s ability to do a proper Valsalva maneuver; (2) frequently provided a corrupted waveform with relative movement; (3) precluded the ability to evaluate the Flow Weighted Average (FWA) at subject interface. A mouthpiece could be used in lieu of a cannula but posed challenges as well: (1) created potential disturbances of the flow field; (2) precluded the test subject from speaking during usage; and (3) presented comfort issues limiting the duration of test points. These challenges made it impractical to use a mouthpiece for anything other than short lab ambient environment tests. Technology development and NASA investment have afforded new capabilities to address some of these measurements providing improved data collection and are implemented in the In-suit CO 2 Washout Test System (ICWTS) which provides suit inlet/outlet pressure, temperature, relative humidity, partial pressure of oxygen, partial pressure of CO 2 , and flow measurement coupled with the acquisition of the inspired PPCO 2 including the ability for FWA measurement. This test system, coupled with use of the In-suit Respiration Mannequin Assembly (IRMA) and Computational Fluid Dynamics (CFD) combine to provide a full picture of the in-suit oro-nasal flow field and effectiveness of CO 2 washout in a spacesuit design.
Colin Campbell↗
Low-Dose Neutron Irradiation Effects on Mechanical Properties of Additively Manufactured 316SS
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36 MATERIALS SCIENCE↗
Lattice QCD study of the Boer-Mulders effect in a pion
The three-dimensional momenta of quarks inside a hadron are encoded in transverse momentumdependent parton distribution functions (TMDs). Our work presents an exploratory lattice QCD study of a TMD observable in the pion describing the Boer-Mulders effect, which is related to polarized quark transverse momentum in an unpolarized hadron. The primary goal is to gain insight into the behavior of TMDs as a function of a Collins-Soper evolution parameter, $\hat{ζ}$, which quantifies the rapidity difference between the hadron momentum and a vector describing the trajectory of the struck quark, e.g., in a semiinclusive deep-inelastic scattering (SIDIS) process. The lattice calculation, performed at the pion mass m π = 518 MeV, utilizes a definition of TMDs via hadronic matrix elements of a quark bilocal operator with a staple-shaped gauge connection; in this context, the evolution parameter is related to the staple direction. By parametrizing the aforementioned matrix elements in terms of invariant amplitudes, the problem can be cast in a Lorentz frame suited for the lattice calculation. Aided by the lower mass of the pion, compared to the nucleon studied previously, the present investigation of pion TMD observables constitutes an important step towards the quantitative study of the physically important regime of large relative rapidity where the dependence on $\hat{ζ}$ appears to approach a limit. Even though matching to perturbative evolution equations in $\hat{ζ}$ is not yet available, extrapolations based on Ansätze containing inverse powers of $\hat{ζ}$ yield stable results with an uncertainty as low as 20%, and both upper and lower bounds for the asymptotics are obtained. In passing, the similarity between the Boer-Mulders effects extracted in the pion and the nucleon is indicated.
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
Magnetostriction-Polarization Coupling in Multiferroic Mn2MnWO6
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99 GENERAL AND MISCELLANEOUS↗
Verification and validation of integrated simulation of energetic particles in fusion plasmas
Here, we report on verification and validation of linear simulations of Alf´ven eigenmodes in the current ramp phase of DIII-D L-mode discharge #159243 using gyrokinetic, gyrokinetic-MHD hybrid, and eigenvalue codes. Using a classical fast ion profile, all simulation codes find that reversed shear Alf´ven eigenmodes (RSAE) are the dominant instability. The real frequencies from all codes have a coefficient of variation of less than 5% for the most unstable modes with toroidal mode number n = 4 and 5. Due to uncertainty in the experimentally measured minimum safety factor (q min ) and the sensitivity of the RSAE’s frequency to q min , the average difference in frequency between simulated and measured is df/f = 14.7%, 22.6%, for n = 4 and 5, respectively. If qmin is adjusted slightly, within experimental errors, an agreement of within 4.5% and 3.1%, for n = 4 and 5 respectively, is found for all codes. The simulated growth rates exhibit greater variation, and simulations find that pressure gradients of thermal plasmas make a significant contribution to the growth rates. Mode structures of the dominant modes agree well among all codes. Using a calculated fast ion profile that takes into account the action of the spectrum of multiple unstable modes, a toroidal Alf´ven eigenmode (TAE) with n = 6 is found to be unstable in the outer edge, consistent with the experimental data. Variations of the real frequencies and growth rates of the TAE are slightly larger than those of the RSAE. Lastly, electron temperature fluctuations and radial phase shifts from simulations show no significant differences with the experimental data for the strong n = 4 RSAE, but significant differences for the weak n = 6 TAE. The verification and validation for the linear simulations of Alf´ven eigenmodes is the first step to determine an integrated simulation of energetic particles confinement in burning plasmas incorporating multiple physical processes with kinetic effects of both energetic and thermal particles on an equal footing.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
Bandgap and Carrier Transport Engineering of Quantum Confined Mixed Phase Nanocrystalline/Amorphous Silicon
Mixed phase nanocrystalline/amorphous-silicon (nc/a-Si:H) thin films with band-gap higher than bulk silicon are prepared by depositing silicon nanoparticles (SiNPs), prepared in a separate deposition zone, and hydrogenated amorphous silicon (a-Si:H), simultaneously. Since the two deposition phases are well decoupled, optimized parameters for each component can apply to the growth process. Photoluminescence spectroscopy (PL) shows that the embedded SiNPs are small enough to exhibit quantum confinement effects. The low temperature PL measurements on the mixed phase reveal a dominant emission feature, which is associated with SiNPs surrounded by a-Si:H. In addition, we compare time dependent low temperature PL measurements for both a-Si:H and mixed phase material under intensive laser exposure for various times up to two hours. The PL intensity of a-Si:H with embedded SiNPs degrades much less than that of pure a-Si:H. We propose this improvement of photostability occurs because carriers generated in the a-Si:H matrix quickly transfer into SiNPs and recombine there instead of recombining in a-Si:H and creating defect states (Staebler-Wronski Effect).
14 SOLAR ENERGY↗
CMM Sequential Analysis Program
This report documents a design agency (DA) method to evaluate coordinate measuring machine (CMM) data by constructing an algorithm that is equivalent to the production agency (PA) algorithm for processing the raw CMM data. Several refinements of the CMM analyses were implemented at both the PA and the DA to process inherent limitations of the raw data, such as the absence of measurements at the exact ends of the connector-adapter assembly (CAA) and the recovery from these limitations through (worst-case) adjustments to the the positional errors. Also, inherent errors of the CMM measurements were accommodated by introducing a guard band, which effectively lowered the tolerance so that the CMM code could not pass bad parts. The DA and the PA showed remarkable agreement in all areas of analysis. The ultimate comparison is shown in Figures 13a and 13b, where the effect of using a guard band and end adjustments to the CMM measurements were clearly shown.
42 ENGINEERING↗
Effects of ionizing radiation on CCD's
The effects of 1.2 MeV gamma radiation and 20 MeV electrons on the operational characteristics of CCDs are studied. The effects of ionizing radiation on the charge transfer efficiency, dark current, and input/output circuitry are described. The improved radiation hardness of buried channel CCDs is compared to surface channel results. Both ion implanted and epitaxial layer buried channel device results are included. The advantages of using a single thickness SiO2 gate dielectric are described. The threshold voltage shifts and surface state density changes of dry, steam, and HCl doped oxides are discussed. Recent results on the recovery times and total dose effects of high dose rate pulses of 20 MeV electrons are reported.
Hartsell, G. A.↗
Evaluation of leading- and trailing-edge flaps on flat and cambered delta wings at supersonic speeds
An experimental investigation has been conducted to evaluate the effectiveness of leading- and trailing-edge flaps on a flat and cambered wing at superconic speeds. Results from the experimental tests showed that highly complex and three-dimensional flow can occur over the wings with leading- and/or trailing-edge flaps deflected. An analysis of the data also showed that flap effectiveness varies significantly between a cambered and flat wing of identical planform and flap geometry. Mach number effects are similar for both flat and cambered wings for all aerodynamic parameters.
Hernandez, Gloria↗
The AXAF CCD imaging spectrometer
The current status of the instrument design and the status of the CCDs being fabricated for the AXAF CCD Imaging Spectrometer (ACIS) are summarized. The instrument consists of an image recording array of CCDs and a linear arrangement of CCDs to record the spectra formed by the objective grating spectrometer. Both arrays employ CCDs with pixel dimensions which correspond to about 0.5 arcsec samples of the image. The CCDs provide moderate spectral resolution and good detection efficiency over the energy range 0.5 to 10 keV. Spectral resolution of 200 or more is achievable using the objective grating with the grating array. Radiation damage effects are shown to degrade the energy resolution of CCDs. Specially designed CCD pixel architecture is employed together with shielding and low temperature operation to slow the effects of radiation damage.
Garmire, G. P.↗