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At least 127 records · Page 7

Comparison of soleus muscles from rats exposed to microgravity for 10 versus 14 days

The effects of two different duration space-flights on the extent of atrophy, fiber type composition, and myosin heavy chain (MHC) content of rat soleus muscles were compared. Adult male Fisher rats (n=12) were aboard flight STS-57 and exposed to 10 days of microgravity and adult ovariectomized female Spraque-Dawley rats (n=12) were aboard flight STS-62 for 14 days. Soleus muscles were bilaterally removed from the flight and control animals and frozen for subsequent analyses. Muscle wet weights, fiber types (I, IC, IIC, and IIA), cross-sectional area, and MHC content were determined. Although a significant difference was found between the soleus wet weights of the two ground-based control groups, they were similar with regard to MHC content (ca 90% MHCI and ca 10% MHCIIa) and fiber type composition. Unloading of the muscles caused slow-to-fast transformations which included a decrease in the percentage of type I fibers and MHCI, an increase in fibers classified as type IC, and the expression of two fast myosin heavy chains not found in the control rat soleus muscles (MHCIId and MHCIIb). Although the amount of atrophy (ca 26%) and the extent of slow-to-fast transformation (decrease in the percentage of MHCI from 90% to 82.5%) in the soleus muscles were similar between the two spaceflights, the percentages of the fast MHCs differed. After 14 days of spaceflight, the percentage of MHCIIa was significantly lower and the percentages of MHCIId and MHCIIb were significantly higher than the corresponding MHC content of the soleus muscles from the 10-day animals. Indeed, MHCIId became the predominant fast MHC after 14 days in space. These data suggest fast-to-faster transformations continued during the longer spaceflight.

short duration↗

Gender differences in endocrine responses to posture and 7 days of -6 degrees head-down bed rest

Endocrine regulation of fluids and electrolytes during 7 days of -6 degrees head-down bed rest (HDBR) was compared in male (n = 8) and, for the first time, female (n = 8) volunteers. The subjects' responses to quiet standing for 2 h before and after HDBR were also tested. In both sexes, diuresis and natriuresis were evident during the first 2-3 days of HDBR, resulting in a marked increase in the urinary Na(+)-to-K+ ratio and significant Na+ retention on re-ambulation. After the 1st day of HDBR, plasma renin activity (PRA) was increased relative to aldosterone (Aldo), plasma volume was decreased, and the renal response to Aldo appeared to be appropriate. Circulating levels of arginine vasopressin, cortisol, and ACTH were unchanged during HDBR. Plasma testosterone decreased slightly on day 2 of HDBR in males. The ratio of early morning ACTH to cortisol was lower in females than in males because ACTH was lower in females. Urinary cortisol increased and remained elevated throughout the HDBR in males only. There were no gender differences in the responses to 7 days of HDBR, except those in the pituitary-adrenal system; those differences appeared unrelated to the postural change. The provocative cardiovascular test of quiet standing before and after HDBR revealed both sex differences and effects of HDBR. There were significant sex differences in cardiovascular responses to standing before and after HDBR. Females had greater PRA and Aldo responses to standing before HDBR and larger Aldo responses to standing after HDBR than males.(ABSTRACT TRUNCATED AT 250 WORDS).

NASA Discipline Number 14-10↗

On the Relationship Between Spotless Days and the Sunspot Cycle: A Supplement

This study provides supplemental material to an earlier study concerning the relationship between spotless days and the sunspot cycle. Our previous study, Technical Publication (TP)-2005-213608 determined the timing and size of sunspot minimum and maximum for the new sunspot cycle, relative to the occurrence of the first spotless day during the declining phase of the old sunspot cycle and the last spotless day during the rising portion of the new cycle. Because the number of spotless days (NSD) rapidly increases as the cycle nears sunspot minimum and rapidly decreases thereafter, the size and timing of sunspot minimum and maximum might be more accurately determined using a higher threshold for comparison, rather than using the first and last spotless day occurrences. It is this aspect that is investigated more thoroughly in this TP.

Wilson, Robert M.↗

Baroreflex Sensitivity Decreases During 90-Day Bed Rest

Baroreflex sensitivity (BRS) decreases during spaceflight and simulated spaceflight (head down bed rest [BR]). However, previous studies have only examined BRS in response to a limited blood pressure (BP) range or to a single sudden change in BP. PURPOSE: The purpose of this study was to examine BRS during 90 days of 6deg head-down tilt BR over a broad range of BP perturbations. METHODS: Nineteen normal volunteers (12M, 7F) were tested one day before BR, and then near BR days 30, 60 and 90. BP was pharmacologically altered by continuous infusions of phenylephrine (PE) and sodium nitroprusside (SNP). Electrocardiogram and continuous BP were collected during 10 min of normal saline (NS), followed by increasing concentrations of PE (10 min each of 0.4, 0.8 and 1.6 micro-g/kg/min). After a 20 min break, NS was infused again for 10 min, followed by increasing concentrations of SNP (10 min each of 0.4, 0.8, 1.2 micro-g/kg/min). Baroreceptor sensitivity was measured as the slope of a sequence of 3 or more beats in which the systolic BP and following R-R interval (RR) both increased or decreased. Spectral heart rate variability (HRV) and mean RR were analyzed using data from only the NS infusions. Two-way repeated-measures analysis of variance was performed to examine the effects of BR and gender. RESULTS: RR decreased (p<0.001) from pre- BR across BR days. High frequency in normalized units, a measure of parasympathetic activity, decreased with BR (p=0.027) and was lower (p=0.046) in men (0.39+/-0.02, mean+/-SEM) than women (0.48+/-0.02). The spontaneous baroreflex slope, our measure of BRS, increased with PE and decreased with SNP across BR (p<0.001). The percentage decrease in BRS from pre- to post-BR appeared to be larger in women (43.6+/-7.0%) than in men (31.3+/-3.9%, p=0.06). CONCLUSION: Parasympathetic activity and baroreflex sensitivity decrease during 90 days of BR, and BRS tends to diminish more in women than in men.

Stenger, M. B.↗

Association Between Cardiovascular and Intraocular Pressure Changes in a 14-Day 6 deg Head Down Tilt (HDT) Bed Rest Study: Possible Implications in Retinal Anatomy

Visual symptoms and intracranial pressure increase reported in astronauts returning from long duration missions in low Earth-orbit are thought to be related to fluid shifts within the body due to microgravity exposure. Because of this possible relation to fluid shifts, studies conducted in head-down tilt (HDT) bed rest are being monitored for potential changes in ocular health. These measures will also serve to determine whether HDT is a suitable ground-based analog to model subclinical cardiovascular and ocular changes that could shed light on the etiology of the VIIP syndrome observed in spaceflight. Sixteen healthy normotensive (12M, 4F, age range 29-54 years), non-smoker and normal weight subjects, volunteered to participate in a 14 day 6 deg head HDT study conducted at the NASA Flight Analogs Research Unit (FARU). This facility provides standard bed rest conditions (diet, wake/sleep time, time allowed in sunlight) during the time that the subjects stay at the FARU. Cardiovascular parameters were obtained in supine posture at BR-5, BR+0, and BR+3 and ocular monitoring was performed weekly. Intraocular pressure (IOP) increased from pre-bed rest BR-3) to the third day into bed rest (BR+3). Values reached a plateau towards the end of the bed rest phase (BR10) and decreased within the first three days of recovery (BR+2) returning to levels comparable to baseline at BR-3. As expected, most cardiovascular parameters were affected by 14 days of HDT bed rest. Plasma volume decreased as a result of bed rest but recovered to baseline levels by BR+3. Indications of cardiovascular deconditioning included increase in both systolic and diastolic blood pressure and heart rate, and a decrease in stroke volume and cardiac output between BR-5 and BR+3. Due to the experimental design of this study, we were not able to test the hypothesis that fluid shifts might be involved in the IOP increase during the bed rest phase, since cardiovascular measures were not available for those time points. There was no correlation between the largest change in IOP (BR-3 versus BR3) and cardiovascular measure changes between baseline (BR-5) and post bed rest (BR+2). While no clinically relevant visual changes were observed during the study, measurement of various retinal parameters was performed with optical coherence tomography (OCT). A decrease in central subfield retinal thickness was observed between BR+2 and baseline at BR-10, but no association was observed with IOP changes. This work investigates the time course of changes in IOP during 14-day HDT bed rest in an attempt to characterize HDT bed rest as a model of the VIIP syndrome and delve into its etiology.

Cromwell, Ronita↗

Analysis of Present Day and Future OH and Methane Lifetime in the ACCMIP Simulations

Results from simulations performed for the Atmospheric Chemistry and Climate Modeling Intercomparison Project (ACCMIP) are analysed to examine how OH and methane lifetime may change from present day to the future, under different climate and emissions scenarios. Present day (2000) mean tropospheric chemical lifetime derived from the ACCMIP multi-model mean is 9.8+/-1.6 yr (9.3+/-0.9 yr when only including selected models), lower than a recent observationally-based estimate, but with a similar range to previous multi-model estimates. Future model projections are based on the four Representative Concentration Pathways (RCPs), and the results also exhibit a large range. Decreases in global methane lifetime of 4.5 +/- 9.1% are simulated for the scenario with lowest radiative forcing by 2100 (RCP 2.6), while increases of 8.5+/-10.4% are simulated for the scenario with highest radiative forcing (RCP 8.5). In this scenario, the key driver of the evolution of OH and methane lifetime is methane itself, since its concentration more than doubles by 2100 and it consumes much of the OH that exists in the troposphere. Stratospheric ozone recovery, which drives tropospheric OH decreases through photolysis modifications, also plays a partial role. In the other scenarios, where methane changes are less drastic, the interplay between various competing drivers leads to smaller and more diverse OH and methane lifetime responses, which are difficult to attribute. For all scenarios, regional OH changes are even more variable, with the most robust feature being the large decreases over the remote oceans in RCP8.5. Through a regression analysis, we suggest that differences in emissions of non-methane volatile organic compounds and in the simulation of photolysis rates may be the main factors causing the differences in simulated present day OH and methane lifetime. Diversity in predicted changes between present day and future OH was found to be associated more strongly with differences in modelled temperature and stratospheric ozone changes. Finally, through perturbation experiments we calculated an OH feedback factor (F) of 1.24 from present day conditions (1.50 from 2100 RCP8.5 conditions) and a climate feedback on methane lifetime of 0.33+-0.13 yr/K, on average. Models that did not include interactive stratospheric ozone effects on photolysis showed a stronger sensitivity to climate, as they did not account for negative effects of climate-driven stratospheric ozone recovery on tropospheric OH, which would have partly offset the overall OH/methane lifetime response to climate change.

atmospheric composition↗

NASA Space Science Day Events-Engaging Students in Science

The NASA Space Science Day Event follows the same format of planning and execution at all host universities and colleges. These institutions realized the importance of such an event and sought funding to continue hosting NSSD events. In 2014, NASA Johnson Space Center ARES team has supported the following universities and colleges that have hosted a NSSD event; the University of Texas at Brownsville, San Jacinto College, Georgia Tech University and Huston-Tillotson University. Other universities and colleges are continuing to conduct their own NSSD events. NASA Space Science Day Events are supported through continued funding through NASA Discovery Program. Community Night begins with a NASA speaker and Astromaterials display. The entire community surrounding the host university or college is invited to the Community Night. This year at the Huston-Tillotson (HTU) NSSD, we had Dr. Laurie Carrillo, a NASA Engineer, speak to the public and students. She answered questions, shared her experiences and career path. The speaker sets a tone of adventure and discovery for the NSSD event. After the speaker, the public is able to view Lunar and Meteorite samples and ask questions from the ARES team. The students and teachers from nearby schools attended the NSSD Event the following day. Students are able to see the university or college campus and the university or college mentors are available for questions. Students rotate through hour long Science Technology Engineering and Mathematics (STEM) sessions and a display area. These activities are from the Discovery Program activities that tie in directly with k- 12 instruction. The sessions highlight the STEM in exploration and discovery. The Lunar and Meteorite display is again available for students to view and ask questions. In the display area, there are also other interactive displays. Angela Green, from San Jacinto College, brought the Starlab for students to watch a planetarium exhibit for the NSSD at Huston-Tillotson University. Many HTU mentors were leading activities in the display room such as build a comet, volcano layering and robotics manipulation. Students were exposed to a variety STEM career possibilities and information. The students could relate the displays and sessions to what they were learning in school. The HTU mentors made the connection clear for the students. The students ended the event with a mission design presentation. They were able to take what they had learned during the day and were able to create a mission. Students presented their Mission Design and gained confidence in STEM. Conclusion: NASA Space Science Day Events provides an out of school experiential learning environment for students to enhance their STEM curriculum and let students see a college campus. The experiences students gain from attending NSSD gives them the confidence to see themselves on a college campus, possibly majoring in a STEM degree, and understand the importance of completing school.

Foxworth, S.↗

Flash Spectroscopy: Emission Lines From the Ionized Circumstellar Material Around 10-Day-Old Type II Supernovae

Supernovae (SNe) embedded in dense circumstellar material (CSM) may show prominent emission lines in their early-time spectra (< or =10 days after the explosion), owing to recombination of the CSM ionized by the shock-breakout flash. From such spectra ("flash spectroscopy"), we can measure various physical properties of the CSM, as well as the mass-loss rate of the progenitor during the year prior to its explosion. Searching through the Palomar Transient Factory (PTF and iPTF) SN spectroscopy databases from 2009 through 2014, we found 12 SNe II showing flash-ionized (FI) signatures in their first spectra. All are younger than 10 days. These events constitute 14% of all 84 SNe in our sample having a spectrum within 10 days from explosion, and 18% of SNe II observed at ages <5 days, thereby setting lower limits on the fraction of FI events. We classified as "blue/featureless" (BF) those events having a first spectrum that is similar to that of a blackbody, without any emission or absorption signatures. It is possible that some BF events had FI signatures at an earlier phase than observed, or that they lack dense CSM around the progenitor. Within 2 days after explosion, 8 out of 11 SNe in our sample are either BF events or show FI signatures. Interestingly, we found that 19 out of 21 SNe brighter than an absolute magnitude M(sub R) = −18.2 belong to the FI or BF groups, and that all FI events peaked above M(sub R) = −17.6 mag, significantly brighter than average SNe II.

supernovae: general↗

A Quasi-Global Approach to Improve Day-Time Satellite Surface Soil Moisture Anomalies through the Land Surface Temperature Input

Passive microwave observations from various spaceborne sensors have been linked to the soil moisture of the Earth's surface layer. A new generation of passive microwave sensors are dedicated to retrieving this variable and make observations in the single theoretically optimal L-band frequency (1-2 GHz). Previous generations of passive microwave sensors made observations in a range of higher frequencies, allowing for simultaneous estimation of additional variables required for solving the radiative transfer equation. One of these additional variables is land surface temperature, which plays a unique role in the radiative transfer equation and has an influence on the final quality of retrieved soil moisture anomalies. This study presents an optimization procedure for soil moisture retrievals through a quasi-global precipitation-based verification technique, the so-called Rvalue metric. Various land surface temperature scenarios were evaluated in which biases were added to an existing linear regression, specifically focusing on improving the skills to capture the temporal variability of soil moisture. We focus on the relative quality of the day-time (01:30 pm) observations from the Advanced Microwave Scanning Radiometer for Earth Observing System (AMSR-E), as these are theoretically most challenging due to the thermal equilibrium theory, and existing studies indicate that larger improvements are possible for these observations compared to their night-time (01:30 am) equivalent. Soil moisture data used in this study were retrieved through the Land Parameter Retrieval Model (LPRM), and in line with theory, both satellite paths show a unique and distinct degradation as a function of vegetation density. Both the ascending (01:30 pm) and descending (01:30 am) paths of the publicly available and widely used AMSR-E LPRM soil moisture products were used for benchmarking purposes. Several scenarios were employed in which the land surface temperature input for the radiative transfer was varied by imposing a bias on an existing regression. These scenarios were evaluated through the Rvalue technique, resulting in optimal bias values on top of this regression. In a next step, these optimal bias values were incorporated in order to re-calibrate the existing linear regression, resulting in a quasi-global uniform LST relation for day-time observations. In a final step, day-time soil moisture retrievals using the re-calibrated land surface temperature relation were again validated through the Rvalue technique. Results indicate an average increasing Rvalue of 16.5%, which indicates a better performance obtained through the re-calibration. This number was confirmed through an independent Triple Collocation verification over the same domain, demonstrating an average root mean square error reduction of 15.3%. Furthermore, a comparison against an extensive in situ database (679 stations) also indicates a generally higher quality for the re-calibrated dataset. Besides the improved day-time dataset, this study furthermore provides insights on the relative quality of soil moisture retrieved from AMSR-E's day- and night-time observations.

soil moisture↗

A ~60 day Super-orbital Period Originating from the Ultraluminous X-ray Pulsar in M82

Ultraluminous X-ray (ULX) pulsars are a new class of object powered by apparent super-critical accretion onto magnetized neutron stars. Three sources in this class have been identified so far; M82X-2, NGC 5907 ULX-1, and NGC 7793 P13 have been found to have two properties in common; ∼1 s spin periods, and for NGC 5907 ULX-1 and NGC 7793 P13 periodic X-ray flux modulations on timescales of ∼60–80 days. M82 X-2 resides in a crowded field that includes the ULX M82 X-1 separated from X-2 by 5″, as well as other bright point sources. A 60 day modulation has been observed from the region, but the origin has been difficult to identify; both M82 X-1 and X-2 have been suggested as the source. In this paper we present the analysis of a systematic monitoring campaign by Chandra, the only X-ray telescope capable of resolving the crowded field. From a simple Lomb–Scargle periodogram analysis and a more sophisticated Gaussian Process analysis we find that only X-2 exhibits a periodic signal around 60 days, supporting previous claims that it is the origin. We also construct a phase-averaged flux profile of the modulations from higher-cadence Swift/XRT data and find that the flux variations in the Chandra data are fully consistent with the flux profile. Since the orbit of the neutron star and its companion is known to be 2.5 days, the ∼60 day period must be super-orbital in origin. The flux of the modulations varies by a factor of ∼100 from the minimum to the maximum, with no evidence for spectral variations, making the origin difficult to explain.

Individual galaxies↗

Identification of Climatological Representative Days in the Mid-Atlantic for High-Fidelity Offshore Wind Energy Modeling

The goal of reaching 30 GW of offshore wind energy by 2030 becomes more realistic with the continued approval of offshore wind energy areas by the Biden Administration. In the Mid-Atlantic, where wind energy projects are in the most advanced stages of development, there is increased research focus on the eventual interaction of these wind farms. These interactions, in the form of wakes and cluster wakes, or wakes from multiple wind farms, could have detrimental effects on power production and forecastability for downwind wind farms (Pryor et al. 2022, Golbazi et al. 2022, Rosencrans et al. 2023). To help alleviate these issues, numerical simulations in the form of numerical weather prediction (NWP) and large eddy simulations (LES) can provide insight into when cluster wake situations may occur, but running such simulations can be expensive and difficult to run for multiple years. In this study, we leverage and build upon existing techniques in the literature (Fischereit et al. 2022) to identify climatologically representative days for wind energy areas in the Mid-Atlantic where conditions would promote cluster wake situations. We select meteorological variables (wind speed, wind direction, atmospheric stability, boundary-layer height, TKE) critical to understanding wind energy production and wake propagation. We then consider two different NWP datasets of varying spatial and temporal resolution: ERA5 provides data at hourly intervals from 1940 to present at 0.25 deg (31 km) spatial resolution (Hersbach et al. 2020), and the NOW-23 dataset provides data at 5-minute resolution for 21 years at 2-km spatial resolution (Bodini et al. 2020). Our first step is to compare these two datasets for an overlapping 21-year time period. Initial results show that the required number of days to represent the long-term climate increases with each additional variable considered. In their study of the German Bight, Fischereit et al. (2022) found that they could represent the long-term wind and wave climate in a "near-perfect" way with -180 days, by reaching a Perkins Skill Score (PSS) of 0.9; our investigation of the mid-Atlantic wind resource region with ERA5 and NOW-23 data suggests that we will need -100 days to reach a PSS of 0.9. As we expand our parameter space to include multiple variables, the number of required days will likely grow. These results will ultimately be used to select case studies to best represent cluster wake conditions that apply to this region for the lifetime of likely wind farms in this mid-Atlantic region.

clusterwakes↗

Comparative Analysis of Machine Learning Models for Day-Ahead Photovoltaic Power Production Forecasting

A main challenge for integrating the intermittent photovoltaic (PV) power generation remains the accuracy of day-ahead forecasts and the establishment of robust performing methods. The purpose of this work is to address these technological challenges by evaluating the day-ahead PV production forecasting performance of different machine learning models under different supervised learning regimes and minimal input features. Specifically, the day-ahead forecasting capability of Bayesian neural network (BNN), support vector regression (SVR), and regression tree (RT) models was investigated by employing the same dataset for training and performance verification, thus enabling a valid comparison. The training regime analysis demonstrated that the performance of the investigated models was strongly dependent on the timeframe of the train set, training data sequence, and application of irradiance condition filters. Furthermore, accurate results were obtained utilizing only the measured power output and other calculated parameters for training. Consequently, useful information is provided for establishing a robust day-ahead forecasting methodology that utilizes calculated input parameters and an optimal supervised learning approach. Finally, the obtained results demonstrated that the optimally constructed BNN outperformed all other machine learning models achieving forecasting accuracies lower than 5%.

14 SOLAR ENERGY↗

Microbial Metagenomes Across a Complete Phytoplankton Bloom Cycle: High-Resolution Sampling Every 4 Hours Over 22 Days

In May and June of 2021, marine microbial samples were collected for DNA sequencing in East Sound, WA, USA every 4 hours for 22 days. This high temporal resolution sampling effort captured the last 3 days of a Rhizosolenia sp. bloom, the initiation and complete bloom cycle of Chaetoceros socialis (8 days), and the following bacterial bloom (2 days). Metagenomes were completed on the time series, and the dataset includes 128 size-fractionated microbial samples (0.22–1.2 µm), providing gene abundances for the dominant members of bacteria, archaea, and viruses. This dataset also has time-matched nutrient analyses, flow cytometry data, and physical parameters of the environment at a single point of sampling within a coastal ecosystem that experiences regular bloom events, facilitating a range of modeling efforts that can be leveraged to understand microbial community structure and their influences on the growth, maintenance, and senescence of phytoplankton blooms.

59 BASIC BIOLOGICAL SCIENCES↗

Zero-day Attack Detection in Digital Substations Using In-Context Learning

In this paper, we address the critical challenge of detecting zero-day attacks in digital substations that employ the IEC-61850 communication protocol to ensure the security and reliability of modern power systems. While many heuristic and machine learning (ML)-based methods have been proposed for attack detection in IEC-61850 digital substations, generalization to unknown or zero-day attacks remains a challenge. We propose an approach that leverages the in-context learning ability of transformer architecture, which enables the model to learn from a few examples of a new task without explicit retraining. Our experiments on the IEC-61850 dataset demonstrate that the proposed method achieves more than 87% detection accuracy on zero-day attacks while the existing baselines fail. We believe this work has the potential to enhance the security of digital substations by enabling the effective detection of zero-day attacks.

LIu, Chen-Ching [Virginia Tech] (ORCID:00000002894↗

Two-Day Westward-Propagating Inertio-Gravity Waves during GoAmazon

The dynamical and thermodynamical features of Amazonian 2-day westward-propagating inertia–gravity (WIG) waves are examined. On the basis of a linear regression analysis of satellite brightness temperature and data from the 2014–15 Observations and Modeling of the Green Ocean Amazon (GoAmazon) field campaign, it is shown that Amazonian WIG waves exhibit structure and propagation characteristics consistent with the n = 1 WIG waves from shallow water theory. These WIG waves exhibit a pronounced seasonality, with peak activity occurring from March to May and a minimum occurring from June to September. Evidence is shown that mesoscale convective systems over the Amazon are frequently organized in 2-day WIG waves. Results suggest that many of the Amazonian WIG waves come from preexisting 2-day waves over the Atlantic, which slow down when coupled with the deeper, more intense convection over tropical South America. In contrast to WIG waves that occur over the ocean, Amazonian 2-day WIG waves exhibit a pronounced signature in surface temperature, moisture, and heat fluxes.

54 ENVIRONMENTAL SCIENCES↗

2023 Sandia Day at UT Austin

On Wednesday, March 8 th and Thursday, March 9 th , 2023, the University of Texas at Austin hosted Sandia National Laboratories (Sandia) for “Sandia Day 2023 at UT Austin” with the intention of reviewing, planning and shaping ongoing and future collaborations in key areas that reflect each organization’s priorities and strengths. The event brought together nearly 100 UT and Sandia participants including executive leadership, researchers, faculty, staff, and students. The primary sessions of Sandia Day consisted of a half-day tour of select J.J. Pickle Research Campus facilities, a networking happy hour, leadership meetings, presentations by both Sandia and UT Austin representatives in areas of research strategic priorities: Grid Resiliency, Examining Climate Change, and Microelectronics, and a research poster session with lunch. The group also discussed growth opportunities in the following research areas: nuclear and radiation engineering, pulsed power and fusion physics, and digital engineering, specifically as it related to materials discovery and advanced manufacturing. Appendix A contains the full Sandia Day agenda.

99 GENERAL AND MISCELLANEOUS↗

Results of post-test psychological examinations of the crewmen from the 90-day manned test of an advanced regenerative life support system

The following material presents the results of two temporally remote administrations of an identical projective personality assessment device (Rorschach Inkblot) using crew members aboard the 90-day test. The first administration took place during preselection crew psychodiagnostic testing in the period extending from mid-December 1969 through mid-January 1970. Second administration took place in late May and early June, 1971, approximately one year after termination of the test. During the 90-day program duration, the subjects participated in the crew training program, were selected and served as onboard crew during the 90-day test. The testing was undertaken in order to determine the character and extent of change (if any) in basic personality dynamics accompanying or caused by participation in the 90-day test program. Results indicate that significant personality changes occurred in three of the four onboard crew members. A detailed discussion of the results is provided. Objective scores which served as the basis for the discussion are presented in the Appendix.

Seeman, J. S.↗

Seventeen Ketogenic steroids excretion in crewmen in a 90-day manned test of an advanced regenerative life support system

Seventeen KGS (17-Ketogenic steroids) and Na/K were determined in 19 urine specimens collected by each of 4 crewmen during the 90-day test. The specimens represented 10% aliquots of 24-hour collections stored frozen onboard the simulator until passthrough. Electrolytes were analyzed immediately after sample passthrough while the steroids were determined post-test on aliquots of the original sample held at 203 K. Steroid data was corrected for body weight and also for analytical variation in the laboratory urine pool control. Long-term nonspecific responses to low-level stress appear to be reflected by the individual and group mean 17-KGS excretion patterns. The first 39 and the last 20 days of the test were significantly different--and presumably more stressful to the crew--than the period from days 39 to 67. Reduction of adrenocortical function during the mid-test phase is attributed to either an adaptation to chronic or intermittent stress or was the result of an actual reduction in the operational demands of the test during this time. Most remarkable of the metabolic findings is the prevalance of high Na/K ratios and an abrupt peak on day 74 for all 4 crewmen.

Myers, D. J.↗