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At least 127 records · Page 7

Molecular Surface Sampling and Chemical Imaging using Proximal Probe Thermal Desorption/Secondary Ionization Mass Spectrometry

Proximal probe thermal desorption/secondary ionization mass spectrometry was studied and applied to molecular surface sampling and chemical imaging using printed patterns on photopaper as test substrates. With the use of a circular cross section proximal probe with a tip diameter of 50 m and fixed temperature (350 C), the influence of probe-to-surface distance, lane scan spacing, and surface scan speed on signal quality and spatial resolution were studied and optimized. As a compromise between signal amplitude, signal reproducibility, and data acquisition time, a surface scan speed of 100 m/s, probe-to-paper surface distance of 5 m, and lane spacing of 10 m were used for imaging. Under those conditions the proximal probe thermal desorption/secondary ionization mass spectrometry method was able to achieve a spatial resolution of about 50 m as determined by the ability to distinguish surface patterns of known dimensions that were printed on the paper substrate. It is expected that spatial resolution and chemical image quality could be further improved by using probes of smaller cross section size and by incorporating a means to maintain a fixed optimal probe-to-surface distance real time, continuously adapting to the changing topography of the surface during a lane scan.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Proximity-Induced Exchange Interaction: A New Pathway for Quantum Sensing Using Spin Centers in Hexagonal Boron Nitride

Defects in hexagonal boron nitride (hBN), a two-dimensional van der Waals material, have attracted a great deal of interest because of its potential in various quantum applications. Due to hBN’s two-dimensional nature, the spin center in hBN can be engineered in the proximity of the target material, providing advantages over its three-dimensional counterparts, such as the nitrogen-vacancy center in diamond. Here, in this work, we propose a novel quantum sensing protocol driven by exchange interaction between the spin center in hBN and the underlying magnetic substrate induced by the magnetic proximity effect. By first-principles calculation, we demonstrate that the induced exchange interaction dominates over the dipole–dipole interaction by orders of magnitude when in the proximity. The interaction remains antiferromagnetic across all stacking configurations between the spin center in hBN and the target van der Waals magnets. Additionally, we explored the scaling behavior of the exchange field as a function of the spatial separation between the spin center and the targets.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Proximate spin liquid and fractionalization in the triangular antiferromagnet KYbSe 2

The Heisenberg triangular-lattice quantum spin liquid and its phase transitions to nearby magnetic orders have received much theoretical attention, but clear experimental manifestations of these states are rare. Here we demonstrate that a spin-half delafossite material, namely, KYbSe 2 , shows close proximity to the triangular-lattice Heisenberg quantum spin liquid. Using neutron scattering, we identify a diffuse continuum with a sharp lower bound within the measured spectra. Applying entanglement witnesses to the data indicates multipartite entanglement spread between its neighbours, and an analysis of its magnetic-exchange couplings reveals close proximity to the theoretical quantum spin-liquid phase. The key features of the data are reproduced by Schwinger boson theory and tensor network calculations with a substantial next-nearest-neighbour coupling. The strength of the dynamical structure factor at the Brillouin-zone K point shows a scaling collapse down to 0.3 K, indicating the existence of a second-order quantum phase transition. Finally, comparing this with previous theoretical work suggests that the proximate phase at a larger next-nearest-neighbour coupling is a gapped $\mathbb{Z}_{2}$ spin liquid, resolving a long-debated issue. Similar content being viewed by others

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Ex situ elaborated proximity mesoscopic structures for ultrahigh vacuum scanning tunneling spectroscopy

We apply ultrahigh vacuum Scanning Tunneling Spectroscopy (STS) at ultra-low temperature to study proximity phenomena in metallic Cu in contact with superconducting Nb. In order to solve the problem of Cu-surface contamination, Cu(50 nm)/Nb(100 nm) structures are grown by respecting the inverted order of layers on SiO{sub 2}/Si substrate. Once transferred into vacuum, the samples are cleaved at the structure-substrate interface. As a result, a contamination-free Cu-surface is exposed in vacuum. It enables high-resolution STS of superconducting correlations induced by proximity from the underlying superconducting Nb layer. By applying magnetic field, we generate unusual proximity-induced superconducting vortices and map them with a high spatial and energy resolution. The suggested method opens a way to access local electronic properties of complex electronic mesoscopic devices by performing ex situ STS under ultrahigh vacuum.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Proximity induced vortices and long-range triplet supercurrents in ferromagnetic Josephson junctions and spin valves

Using a spin-parameterized quasiclassical Keldysh-Usadel technique, we theoretically study supercurrent transport in several types of diffusive ferromagnetic (F)/superconducting (S) configurations with differing magnetization textures. We separate out the even- and odd-frequency components of the supercurrent within the low proximity limit and identify the relative contributions from the singlet and triplet channels. We first consider inhomogeneous one-dimensional Josephson structures consisting of a uniform bilayer magnetic S/F/F/S structure and a trilayer S/F/F/F/S configuration, in which case the outer F layers can have either a uniform or conical texture relative to the central uniform F layer. Our results demonstrate that for supercurrents flowing perpendicular to the F/F interfaces, incorporating a conical texture yields the most effective way to observe the signatures of long-ranged spin-triplet supercurrents. We also consider three different types of finite-sized two-dimensional magnetic structures subjected to an applied magnetic field normal to the junction plane: a S/F/S junction with uniform magnetization texture and two S/F/F/S configurations with differing F/F bilayer arrangements. In one case, the F/F interface is parallel with the S/F junction interfaces while in the other case, the F/F junction is oriented perpendicular to the S/F interfaces. We then discuss the proximity vortices and corresponding spatial maps of currents inside the junctions. For the uniform S/F/S junction, we analytically calculate the magnetic field induced supercurrent and pair potential in both the narrow and wide junction regimes, thus providing insight into the variations in the Fraunhofer diffraction patterns and proximity vortices when transitioning from a wide junction to a narrow one. Our extensive computations demonstrate that the induced long-range spin-triplet supercurrents can deeply penetrate uniform F/F bilayers when spin-singlet supercurrents flow parallel to the F/F interfaces. This is in stark contrast to configurations where a spin-singlet supercurrent flows perpendicular to the F/F interfaces. We pinpoint the origin of the induced triplet and singlet correlations through spatial profiles of the decomposed total supercurrents. We find that the penetration of the long-range spin-triplet supercurrents associated with supercurrents flowing parallel to the F/F interfaces is more pronounced when the thicknesses of the F strips are unequal. Finally, if one of the S terminals is replaced with a finite-sized normal metal, we demonstrate that the corresponding experimentally accessible S/F/F/N spin valve presents an effective platform in which the predicted long-range effects can be effectively generated and probed.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Direct observation of proximity-induced magnetism and spin reorientation in topological insulator on a ferrimagnetic oxide

The quantum anomalous Hall effect (QAHE) in a magnetic topological insulator system without the need of an external magnetic field becomes of great interest because of its dissipationless spin currents. The proximity effect via a magnetic adlayer is a promising strategy to bring magnetism into a topological insulator (TI) due to its boosted Curie temperature for a realistic application. In this work, a proximity-induced magnetism above 90 K in a TI, (Bi 0.25 Sb 0.75 ) 2 Te 3 , on a ferrimagnetic adlayer with perpendicular magnetic anisotropy, thulium-iron-garnet (TIG), was evidenced directly by using magnetic circular dichroism. A competition between exchange couplings with different sublattice-sites was further revealed element-specifically in a temperature-driven spin-reorientation of TI, bringing an issue on magnetic inhomogeneity at the interface, which might cause difficulties in obtaining QAHE in such a TI/TIG bilayer system. Our results prove directly the robust magnetism of TI above liquid nitrogen temperatures and also give a deep insight into the mechanism of interfacial coupling in the proximity effect for the bilayer of TI and magnetic oxide, which could be essential for the design of a system with QAHE.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Design, construction and commissioning of the proximity cryogenics systems serving two large-scale prototypes of the future DUNE neutrino detector

In the context of the Neutrino Platform, CERN has designed, constructed, and commissioned the proximity cryogenics systems that serve two CERN based large-scale prototypes of future neutrino detectors. Each of these prototypes features a high voltage time projection chamber placed inside a membrane cryostat being submerged in 600m3 of liquid argon at about 1.0 bar. A copper and molecular sieve based cryogenic purification system has to ensure that the argon in the cryostat has a contamination level below 100 ppt oxygen equivalent. The two proximity cryogenics systems provide the purging, cool-down, filling, normal operation and emptying modes for each cryostat. This paper reports on the design, construction and commissioning of the ProtoDUNE proximity cryogenics facilities.

43 PARTICLE ACCELERATORS↗

Reduced Spin Hall Effects from Magnetic Proximity.

We investigate temperature-dependent spin pumping and inverse spin Hall effects in thin Pt and Pd in contact with Permalloy. Our experiments show a decrease of the spin Hall effect with decreasing temperature, which is attributed to a temperature-dependent proximity effect. The spin Hall angle decreases from 0.086 at room temperature to 0.042 at 10 K for Pt and is nearly negligible at 10 K for Pd. By first-principle calculations, we show that the spin Hall conductivity indeed reduces by increasing the proximity-induced spin magnetic moments for both Pt and Pd. This work highlights the important role of proximity-induced magnetic ordering to spin Hall phenomena in Pt and Pd.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

SU-E-T-170: Characterization of the Location, Extent, and Proximity to Critical Structures of Target Volumes Provides Detail for Improved Outcome Predictions Among Pancreatic Cancer Patients

Purpose: In radiotherapy, size, location and proximity of the target to critical structures influence treatment decisions. It has been shown that proximity of the target predicts dosimetric sparing of critical structures. In addition to dosimetry, precise location of disease has further implications such as tumor invasion, or proximity to major arteries that inhibit surgery. Knowledge of which patients can be converted to surgical candidates by radiation may have high impact on future treat/no-treat decisions. We propose a method to improve our characterization of the location of pancreatic cancer and treatment volume extent with respect to nearby arteries with the goal of developing features to improve clinical predictions and decisions. Methods: Oncospace is a local learning health system that systematically captures clinical outcomes and all aspects of radiotherapy treatment plans, including overlap volume histograms (OVH) – a measure of spatial relationships between two structures. Minimum and maximum distances of PTV and OARs based on OVH, PTV volume, anatomic location by ICD-9 code, and surgical outcome were queried. Normalized distance to center from the left and right kidney was calculated to indicate tumor location and laterality. Distance to critical arteries (celiac, superior mesenteric, common hepatic) is validated by surgical status (borderline resectable, locally advanced converted to resectable). Results: There were 205 pancreas stereotactic body radiotherapy patients treated from 2009–2015 queried. Location/laterality of tumor based on kidney OVH show strong trends between location by OVH and by ICD-9. Compared to the locally advanced group, the borderline resectable group showed larger geometrical distance from critical arteries (p=0.03). Conclusion: Our platform enabled analysis of shape/size-location relationships. These data suggest that PTV volume and attention to distance between PTVs and surrounding OARs and major arteries may be promising for improving characterization of treatment anatomy that can refine our ability for outcome predictions and decision making. Elekta, Toshiba.

60 APPLIED LIFE SCIENCES↗

Managing Subsurface Pressure Buildup and Interference in Commercial-Scale CO 2 Storage Project with Proximal Injection Wells

Large-scale decarbonization using carbon capture and storage (CCS) is likely to involve many commercial-scale CO 2 storage projects located in close proximity to each other. This close proximity raises concerns over pressure interference among the storage projects. Pressure interference between injection and storage efforts can reduce the practicable CO 2 storage resource and force wells to inject CO 2 at a lower rate to avoid the fracture pressure thresholds per United States Environmental Protection Agency (EPA) Class VI well regulations to preserve injection and confining zone integrity and potentially mitigate against inducing seismic activity. These analyses employ numerical full-physics reservoir modeling to evaluate how pressure buildup fronts and CO 2 plumes evolve under commercial-scale injection volumes of CO 2 in which multiple storage sites located in close proximity occur in tandem. The simulation models mimic injection at pseudo basin-scale and assume homogeneous saline formation(s) as storage targets with a pair of upper and lower homogeneous seal layer/s. These analyses specifically investigate the efficacy of two basin-wide reservoir pressure management strategies in addressing the technical challenges associated with pressure buildup and CO 2 plume commingling. The strategies explored include: 1) enlarging the area of injection well spacing (WS) and 2) storing CO 2 in a stacked sequence (SSS) of saline formations compared to a single formation. The storage and confining zones properties assumed were held common across the scenarios, unless specified otherwise. Analyses results show that after injecting 4 million tons per year for 30 years using 4 separate wells (each injecting 1 million metric tons per year), the radius of CO 2 plume extends to a mere 3 km or less from injection wells. Meanwhile, the radius of pressure buildup ranges on the order of tens to a few hundreds of kilometers, depending on the magnitude of pressure buildup threshold that one would use to define the front. CO 2 plume commingling from different injection wells appears to occur 50 years post-injection, especially under scenarios with narrowly spaced (i.e., < 5 km apart) injection well locations. Findings from sensitivity cases on the well spacing suggest that storage formations modeled would require different well spacing to avoid fracture pressure thresholds. For instance, modeled storage formations with high fracture gradients (i.e., 0.8 psi/ft) would need less than 5–km well spacing, whereas those with lower fracture gradients (i.e., 0.7 psi/ft) would need approximately 20–km well spacing, based on assumed modeling parameters. Under stacked injection, the pressure challenges (described above) still exist but are more alleviated due to distributing the same injection volume across more available reservoir volume. These analyses demonstrate that stacked-sequence storage can effectively address the challenges, while still providing the same target CO 2 storage volumes and allowing a large number of storage projects to be deployed in the same basin by better utilizing the available storage resource across different reservoir depths. Among cases modeled, the resulting pressure buildup front is most suppressed when each storage project distributes injection volumes over several wells, each of which injects a portion of the total CO 2 across the stacked sequence. This strategy results in the smallest CO 2 aerial footprint amongst scenarios evaluated but also shows the largest reduction in the pressure buildup at the top of perforation at the injection wells (upwards of approximately 42 percent compared to the commercial-scale single-formation storage), the result of which is crucial to maintain caprock integrity. The findings presented by this research draw attention to the importance of greater coordination among storage operators and regulatory stakeholders to foster the upscaling and deployment of CCS. These analyses provide insights into required decision-making when considering multi-project deployment in a shared basin. Because these analyses evaluate a very specific geologic situation, they bear further investigations across other geologic situations.

42 ENGINEERING↗

Limited Support for Thyroid Hormone or Corticosterone Related Gene Expression as a Proximate Mechanism of Incubation Temperature-Dependent Phenotypes in Birds

The conditions that animals experience during early development can have profound consequences for health and fitness. In birds, one of the most important aspects of development is egg incubation temperature. A small decrease in average temperature leads to various impacts on offspring phenotype, such as smaller body sizes, slower growth rates, and less efficient metabolic activity. Little is known, however, about the proximate mechanisms underlying these incubation temperature-induced phenotypic changes. Two important hormones which could play a proximate role are thyroid hormone and corticosterone, which mobilize stored energy reserves and coordinate the normal growth of tissues, particularly in the brain. Previous research shows that circulating blood concentrations of both hormones are influenced by incubation temperature, but the mechanism by which incubation temperature may lead to these changes is unknown. We hypothesized that incubation temperature induces changes in thyroid hormone and corticosterone regulation, leading to changes in expression of hormone-sensitive genes in the brain. To test this, we incubated wood duck (Aix sponsa) eggs at three different temperatures within the natural range (35.0, 35.8, and 37.0°C). We measured mRNA expression of thyroid hormone-related neuroendocrine endpoints (deiodinase 2/3, thyroid hormone receptor α/β, neural regeneration related protein, and Krueppel-like factor 9) in newly hatched ducklings and corticosterone-related neuroendocrine endpoints (mineralocorticoid receptor, glucocorticoid receptor, cholecystokinin, and brain-derived neurotrophic factor) in 15 day-old ducklings using qPCR on brain tissue from the hippocampus and hypothalamus. Contrary to our predictions, we found that mRNA expression of thyroid hormone-related endpoints in both brain areas were largely unaffected by incubation temperature, although there was a trend for an inverse relationship between mRNA expression and incubation temperature for several genes in the hypothalamus. We also found that mineralocorticoid receptor mRNA expression in the hypothalamus was lower in ducklings incubated at the low relative to the high temperatures. This study is the first to evaluate the effects of incubation temperature on mRNA expression of neuroendocrine endpoints in the developing avian brain and suggests that these particular endpoints may be largely resistant to changes in incubation temperature. Thus, further research into the proximate mechanisms for incubation temperature-induced developmental plasticity is needed.

54 ENVIRONMENTAL SCIENCES↗

Effect of Deep Drying and Torrefaction Temperature on Proximate, Ultimate Composition, and Heating Value of 2-mm Lodgepole Pine (Pinus contorta) Grind

Deep drying and torrefaction is a thermal pretreatment method, where biomass is heated in the temperature range of 150–300°C in an inert or reduced environment. The process parameters like temperature and residence time has a significant impact on proximate, ultimate, and energy properties of the biomass. In the present study, torrrefaction experiments were conducted on 2 mm lodgepole pine grind using a thermogravimetric analyzer. Both deep drying and torrefaction temperature (160–270°C) and time (15–120 min) were selected. Torrefied samples were analyzed for proximate, ultimate and energy properties. Results indicated that moisture content decreased with increases in torrefaction temperature and time, where at 270°C and 120 min, the moisture content was found to be 1.15% (w.b.). Volatile content in the biomass decreased from about 80% to about 45%, and ash content increased from 0.77 to about 1.91% at 270°C and 120 min. The hydrogen, oxygen and sulfur content decreased to 3%, 28.24%, and 0.01 whereas carbon content and higher heating value increased to 68.86% and 23.67 MJ/kg at 270°C and 120 min. H/C and O/C ratio calculated at 270°C and 120 min residence time were about 0.56 and 0.47. This study indicated that higher torrefaction temperatures >230°C and residence time >15 min influenced the proximate, ultimate, and energy properties.

09 BIOMASS FUELS↗

Modeling the He II Transverse Proximity Effect: Constraints on Quasar Lifetime and Obscuration

The He II transverse proximity effect - enhanced He II Lyα transmission in a background sightline caused by the ionizing radiation of a foreground quasar - offers a unique opportunity to probe the emission properties of quasars, in particular the emission geometry (obscuration, beaming) and the quasar lifetime. Building on the foreground quasar survey published in Schmidt et al., we present a detailed model of the He II transverse proximity effect, specifically designed to include light travel time effects, finite quasar ages, and quasar obscuration. Here, we post-process outputs from a cosmological hydrodynamical simulation with a fluctuating He ii ultraviolet background model, with the added effect of the radiation from a single bright foreground quasar. We vary the age t age and obscured sky fractions Ω obsc of the foreground quasar, and explore the resulting effect on the He ii transverse proximity effect signal. Fluctuations in intergalactic medium density and the ultraviolet background, as well as the unknown orientation of the foreground quasar, result in a large variance of the He II Lyα transmission along the background sightline. We develop a fully Bayesian statistical formalism to compare far-ultraviolet He ii Lyα transmission spectra of the background quasars to our models, and extract joint constraints on t age and Ω obsc for the six Schmidt et al. foreground quasars with the highest implied He II photoionization rates. Our analysis suggests a bimodal distribution of quasar emission properties, whereby one foreground quasar, associated with a strong He II transmission spike, is relatively old (22 Myr) and unobscured (Ω obsc < 35%), whereas three others are either younger than 10 Myr or highly obscured (Ω obsc > 70%).

79 ASTRONOMY AND ASTROPHYSICS↗

Recovering Density Fields inside Quasar Proximity Zones at z ~ 6

The matter density field at z ~ 6 is very challenging to probe. One of the traditional probes of the low density intergalactic medium that works successfully at lower redshifts is the Lyα forest in quasar spectra. However, at the end of reionization, the residual neutral hydrogen usually creates saturated absorption, thus much of the information about the gas density is lost. Luckily, in a quasar proximity zone, the ionizing radiation is exceptionally intense, thus creating a large region with nonzero transmitted flux. In this study we use the synthetic spectra from simulations to investigate how to recover the density fluctuations inside the quasar proximity zones. We show that, under ideal conditions, the density can be recovered accurately with a small scatter. We also discuss how systematics such as the quasar continuum fitting and reionization models affect the results. This study shows that by analyzing the absorption features inside quasar proximity zones we can potentially constrain quasar properties and the environments they reside in.

79 ASTRONOMY AND ASTROPHYSICS↗

Embedded Ferroelectric Nanoclusters can drive Polarization Reversal in a Non-Ferroelectric Polar Film via the Proximity Effect

Heterogeneous nucleation from defects dominates the electric field required for polarization switching of ferroelectrics. Here, we consider the switching of a nominally non-switchable polar thin film of AlN due to the proximity effect arising from embedded ferroelectric nanoclusters of Al 1-x Sc x N. Using a Landau-Ginzburg-Devonshire thermodynamic approach and finite element modeling, we study the influence of nanocluster shape on polarization switching and domain nucleation emerging in AlN. The ferroelectric nanocluster boundary is modeled as a thin layer transitioning from Al 1-x Sc x N to AlN. We analyze the conditions under which polarization switching in the AlN film occurs at coercive fields significantly lower than its dielectric breakdown field. In the presence of spike-like Al 1-x Sc x N nanoclusters, the proximity effect enables switching of the spontaneous polarization in AlN and significantly reduces the corresponding coercive field. The internal field, which is depolarizing inside the AlN (due to its larger spontaneous polarization) and polarizing within the ferroelectric Al 1-x Sc x N nanoclusters (due to its smaller spontaneous polarization), lowers the potential barrier in the clusters and nucleates nanodomains at the Al 1-x Sc x N-AlN interface, forming localized regions of reversed polarization. Proximity effect can thus provide a pathway towards "thawing" previously "frozen" ferroelectrics through engineered nucleation for memory, actuation and optical technologies.

36 MATERIALS SCIENCE↗

Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity

Enhancers are important regulatory elements that can control gene activity across vast genetic distances. However, the underlying nature of this regulation remains obscured because it has been difficult to observe in living cells. Here, we visualize the spatial organization and transcriptional output of the key pluripotency regulator Sox2 and its essential enhancer Sox2 Control Region (SCR) in living embryonic stem cells (ESCs). We find that Sox2 and SCR show no evidence of enhanced spatial proximity and that spatial dynamics of this pair is limited over tens of minutes. Sox2 transcription occurs in short, intermittent bursts in ESCs and, intriguingly, we find this activity demonstrates no association with enhancer proximity, suggesting that direct enhancer-promoter contacts do not drive contemporaneous Sox2 transcription. Our study establishes a framework for interrogation of enhancer function in living cells and supports an unexpected mechanism for enhancer control of Sox2 expression that uncouples transcription from enhancer proximity.

59 BASIC BIOLOGICAL SCIENCES↗

Results of wind tunnel tests at Mach 5 on the .004 scale model 2A configuration space shuttle to determine proximity effects and orbiter control effectiveness during orbiter/external tank abort separation (IAG)

Results from tests in the NASA/MSFC Trisonic Wind Tunnel on 0.004-Scale Orbiter and External Tank Force Models in Close Proximity (RTLS Abort Separation Conditions) are presented. The primary test objectives were to obtain data concerning proximity effects on the aerodynamic forces and moments experienced by Vehicle 2A Configuration Shuttle Orbiter and External Tank during an abort separation (Return to Launch Site) at a Mach number of 5. Additionally, data on orbiter control effectiveness during such an abort was obtained. Proximity effects were investigated for relative angles of incidence from minus 5 deg to plus 10 deg of the orbiter FRL with respect to the external tank centerline over a range of vertical and longitudinal displacements from the mated position to 2.5 tank diameters below and 3 tank diameters aft of the mated position.

Garton, W. P.↗

Proximity sensor technology for manipulator end effectors

Optical proximity sensing techniques which could be used to help control the critical grasping phase of a remote manipulation are described. The proximity sensors described use a triangulation geometry to detect a surface located in a pre-determined region. The design of the proximity sensors themselves is discussed, as well as their application to manipulator control with a local control loop, and possibilities for future development are discussed.

Johnston, A. R.↗