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At least 127 records · Page 7

Magnetic field and current structures in the magnetosphere of Uranus

Voyager 2 magnetic field and plasma data are compared with theoretical model calculations for the magnetosphere of Uranus to derive a global picture from the limited set of measurements. The results suggest that Voyager 2 entered the Uranian magnetosphere during a relaxation phase which followed a compression of the entire magnetosphere. The plasma beta values in the Uranian neutral sheet were found to be smallar by a factor of 3-8 compared to corresponding beta values in the average terrestrial neutral sheet. The excellent agreement found between observed and calculated magnetic tail lobe field strengths indicates that the Uranian magnetosphere reaches the state of quasi-static (i.e., slowly time-dependent MHD equilibrium).

Voigt, G.-H.↗

Ultraviolet and visible flare observations of EQ Pegasi B

EQ Peg AB (dM43+dM5.5e) was monitored in the visible at the Whipple Observatory and ultraviolet with IUE on September 2, 1981. In the visible spectrophotometry of EQ Peg B the H-beta emission strengthened by a factor of 2 relative to the nearby stellar continuum within a few minutes and decayed over an hour. This flare in EQ Peg B was coincident with the enhancement of ultraviolet emission lines of C IV 1550 A, He II 1640 A, and C II 1335 A in the combined light of EQ Peg AB. The ultraviolet fluxes during the flare can be interpreted as similar to those either in the thermal phases of large two-ribbon solor flares where radiative cooling balances thermal conduction or in gas cooling quickly from X-ray emitting temperatures. The appearance of the ultraviolet continuum at 1700-1900 A and ratio of H-alpha to H-beta fluxes during the flare are consistent with models producing these emissions in the chromosphere.

Baliunas, S. L.↗

Optimal control of the electron temperature profile in DIII-D using machine learning surrogate models

The viability of the tokamak as a potential fusion reactor depends on the ability to keep the plasma in a stable regime while achieving temperatures, densities, and confinement times that are as high as possible. Tokamak scenario development attempts to find plasma regimes that achieve all of these conditions and are accessible with a given set of hardware constraints. This requires the ability to control plasma properties such as the normalized beta, the internal inductance, safety factor, rotation, etc. One property that has received less attention than some of the others, but is no less critical to achieving high performance, is the electron temperature (T e ) profile. In this work, Linear Quadratic Integral (LQI) control is used to develop a controller for the electron temperature profile in DIII-D. The controller is based on a linearized model derived from the transport equation that describes the evolution of the electron temperature, and includes contributions from the neural network surrogate models NubeamNet and MMMnet. Furthermore, the controller is tested in simulation using COTSIM, and is proven capable of tracking a target T e profile.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Calculating the momentum enhancement factor for asteroid deflection studies

The possibility of kinetic-impact deflection of threatening near-Earth asteroids will be tested for the first time in the proposed AIDA (Asteroid Impact Deflection Assessment) mission, involving NASAs DART (Double Asteroid Redirection Test). The impact of the DART spacecraft onto the secondary of the binary asteroid 65803 Didymos at a speed of 5 to 7 km/s is expected to alter the mutual orbit by an observable amount. Furthermore, the velocity transferred to the secondary depends largely on the momentum enhancement factor, typically referred to as beta. Here, we use two hydrocodes developed at Los Alamos, RAGE and PAGOSA, to calculate an approximate value for beta in laboratory-scale benchmark experiments. Convergence studies comparing the two codes show the importance of mesh size in estimating this crucial parameter.

79 ASTRONOMY AND ASTROPHYSICS↗

MHD stability analysis against pressure and current-driven modes in the SMall Aspect Ratio Tokamak

Linear magnetohydrodynamic (MHD) simulations for the SMall Aspect Ratio Tokamak (SMART) have been carried out for the first time, for both positive (PT) and negative triangularity (NT) shaped plasmas using the MARS-F code. The MHD stability of projected SMART plasmas against internal kinks, infernal modes and edge peeling-ballooning modes have been analyzed for a wide range of realistic equilibria. A stabilization of internal kinks and infernal modes is observed when increasing the safety factor profile and reducing plasma beta. PT shaped plasmas are more stable against both internal kinks and infernal modes than their counterpart NT shaped plasmas. Toroidal flows have little impact on the MHD stability of the internal kinks, but they have a strong stabilizing effect on infernal modes, which can be further mitigated in NT shaped plasmas. The MHD stability of peeling-ballooning modes is reduced in NT shaped plasmas, as observed in conventional tokamaks.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

An assessment of lightning or in situ instabilities as a source for whistler mode waves in the night ionosphere of Venus

Low-altitude data acquired on orbits 484-526 of the Pioneer Venus Orbiter are used to assess the most probable source of whistler mode waves in the nightside ionosphere of Venus. The effect of electron temperature on whistler mode propagation is discussed, with particular emphasis on the growth rate of gyroresonant instabilities. The wave intensity as observed with the Pioneer Venus Orbiter electric field detector is compared with various plasma parameters to determine if it is likely that the waves are generated by an in situ instability. It is shown that gyroresonant whistler mode instabilities do not explain the Pioneer Venus wave data. It is demonstrated that the magnetic field strength controls the wave intensity, rather than density, and it is concluded that the electron Beta(e) is the primary factor in the occurrence of the 100-Hz waves detected in the nightside ionosphere of Venus. The present analysis supports the interpretation that these waves are due to lightning in the Venus atmosphere.

Strangeway, R. J.↗

Identifying Neutron Irradiation in Space to Mitigate Bio-Medical Effects

Ubiquitous GCR high energy particles >1 GeV is primary concern • Medical effects compounded by ionizing dose of radiation from energetic particles- cancer, mutations, microbiome changes • Cancer induction and effects are irreversible after initiation • Long term space radiation exposure is cancer promoting but reversible Secondary GCR and Solar induced neutron spallation is a concern • Produced by interactions with space craft materials, EVA and planetary surfaces • Neutron Quality Factor is 10x that of beta, x-ray or gamma rays Space isn’t friendly to life or electronics! Real-time charged particle and EARLY neutron detection are required. Traveling fast or digging deep are the best protection. Nuclear space propulsion through LENR/LCF/Solid-State Fusion is a good bet!

space medicine↗

Variability of Markarian 1018 - Seyfert 1.9 to Seyfert 1

Simultaneous IUE and optical spectrophotometry of the Seyfert 1.9 galaxy Markarian 1018 is presented. The strength of H-beta(broad) has increased by a factor of 6.6 in 4 yr, and the galaxy now shows strong broad UV and optical line emission similar to that seen in normal Seyfert 1 galaxies, but with markedly asymmetric line profiles. As in other variable Seyfert galaxies, H-alpha emission has also increased but by a lesser amount than H-beta. Furthermore, Ly-alpha (not observed during the first epoch) is now quite strong relative to H-beta and H-alpha. Inspection of the line profiles reveals nearly identical blue asymmetric line profiles in all permitted lines; these show evidence of significant profile evolution over a 1 yr time scale. The present line ratios and the nature of their variability suggest that the enhancement in the broad-line emission is not caused by the removal of obscuring dust but by the 'lighting up' of the broad-line region.

Cohen, Ross D.↗

Effect of growth differentiation factor-15 secreted by human umbilical cord blood-derived mesenchymal stem cells on amyloid beta levels in in vitro and in vivo models of Alzheimer's disease

Highlights: • Paracrine action of hUCB-MSCs enhances Aβ clearance through microglial modulation. • GDF-15 secreted from hUCB-MSCs promotes the decrease of Aβ levels via enhancing IDE expression in microglia. • TGFβRII is involved in GDF-15-enhanced IDE expression in microglia. Alzheimer's disease (AD), which is the most common progressive neurodegenerative disease, causes learning and memory impairment. The pathological progress of AD can derive from imbalanced homeostasis of amyloid beta (Aβ) in the brain. In such cases, microglia play important roles in regulating the brain Aβ levels. In the present study, we found that human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) can increase, through paracrine action, the ability of microglial cells to clear Aβ. In order to identify the associated paracrine factors, a secretome of hUCB-MSCs co-cultured with Aβ-treated BV2 microglial cells was analyzed using a human cytokine protein array. As a result, growth differentiation factor-15 (GDF-15) was identified as a predominant candidate, and its association with Aβ clearance by microglial cells was investigated in vitro and in a 5XFAD mouse model. When Aβ-treated BV2 cells were treated with exogenous recombinant GDF-15, the Aβ levels in the culture medium decreased. Moreover, GDF-15 injection in the brain parenchyma of 5XFAD mice also led to decrease in Aβ plaques. In contrast, co-culture of BV2 cells and hUCB-MSCs treated with GDF-15-specific siRNA did not influence the Aβ levels in the culture medium. To elucidate how these phenomena are related, we confirmed that GDF-15 specifically increases insulin-degrading enzyme (IDE) expression in microglial cells through TGFβ receptor type II (TGFβRII), both in vitro and in vivo. These findings suggest that hUCB-MSCs promote the Aβ clearance ability of microglial cells through regulation of GDF-15 secretion, thus elucidating a therapeutic mechanism for AD.

60 APPLIED LIFE SCIENCES↗

Generalized Orbital Projections of a Sublimating Ice Particle

The issue of orbital debris resulting from human activities in space is a growing concern for the space users' community. Waste generated in Low Earth Orbit (LEO) can stay in orbit for a long time, creating significant hazards for other spacecraft flying at lower intercepting orbits. Many spacecraft, especially crewed vehicles, are required to vent fluids into space. These fluids include propellant, wastewater, excess condensate, and others. It is important to analyze the behavior of particles that result from these activities, since each individual particle is capable of damaging or destroying a spacecraft in a lower, crossing orbit, and such particles are invisible to tracking radar systems on the ground. The deorbit trajectory of an ice particle is complex. It depends on factors including attitude of the vehicle during vent, initial velocities of particles, altitude at which the vent occurred, and numerous evaporation and sublimation factors. These include contamination within the vented water, evolution of bubbles within the clear water, and sun flux factors such as time of the year and current beta angle. The purpose of this study is to examine the influences of these factors on the trajectories of ice particles resulting from condensate water dumps, and to bound the safe trajectories of spacecraft that lie below the venting spacecraft.

Menkin, Evgeny↗

Implementation of a Single-Stage-To-Orbit (SSTO) model for stability and control analysis

Three NASA centers: Marshall Space Flight Center (MSFC), Langley Research Center (LaRC), and Johnson Space Center (JSC) are currently involved in studying a family of single-stage- and two-stage-to-orbit (SSTO/TSTO) vehicles to serve as the next generation space transportation system (STS). A rocketed winged-body is the current focus. The configuration (WB001) is a vertically-launched, horizontally-landing system with circular cross-section. Preliminary aerodynamic data was generated by LaRC and is a combination of wind-tunnel data, empirical methods, and Aerodynamic Preliminary Analysis System-(APAS) generated values. JSC's efforts involve descent trajectory design, stability analysis, and flight control system synthesis. Analysis of WB001's static stability indicates instability in 'tuck' (C(sub mu) less than 0: Mach = 0.30, alpha greater than 3.25 deg; Mach = 0.60, alpha greater than 8.04), an unstable dihedral effects (C(sub l(beta)) greater than 0: Mach = 30,alpha less than 12 deg.; Mach = 0.60, alpha less than 10.00 deg.), and, most significantly, an unstable weathercock stability derivative, C(sub n(beta)), at all angles of attack and subsonic Mach numbers. Longitudinal trim solutions for Mach = 0.30 and 0.60 indicate flight path angle possibilities ranging from around 12 (M = 0.30) to slightly over 20 degrees at Mach = 0.60. Trim angles of attack increase from 6.24 at Mach 0.60 and 10,000 feet to 17.7 deg. at Mach 0.30, sea-level. Lateral trim was attempted for a design cross-wind of 25.0 knots. The current vehicle aerodynamic and geometric characteristics will only yield a lateral trim solution at impractical tip-fin deflections (approximately equal to 43 deg.) and bank angles (21 deg.). A study of the lateral control surfaces, tip-fin controllers for WB001, indicate increased surface area would help address these instabilities, particularly the deficiency in C(sub n(beta)), but obviously at the expense of increased vehicle weight. Growth factors of approximately 7 were determined using a design C(sub n(beta)) of 0.100/radian (approximate subsonic values for the orbiter).

Ingalls, Stephen A.↗

Alpha Air Sample Counting Efficiency Versus Dust Loading: Evaluation of a Large Data Set

Dust loading on air sample filters is known to cause a loss of efficiency for direct counting of alpha activity on the filters, but the amount of dust loading and the correction factor needed to account for attenuated alpha particles is difficult to assess. In this paper, correction factors are developed by statistical analysis of a large database of air sample results for a uranium and plutonium processing facility at the Savannah River Site. As is typically the case, dust-loading data is not directly available, but sample volume is found to be a reasonable proxy measure; the amount of dust loading is inferred by a combination of the derived correction factors and a Monte Carlo model. The technique compares the distribution of activity ratios [beta/(beta + alpha)] by volume and applies a range of correction factors on the raw alpha count rate. The best-fit results with this method are compared with MCNP modeling of activity uniformly deposited in the dust and analytical laboratory results of digested filters. Finally, a linear fit is proposed to evenly-deposited alpha activity collected on filters with dust loading over a range of about 2 mg cm -2 to 1,000 mg cm -2 .

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Neutrino masses from low scale partial compositeness

We consider a class of models in which the neutrinos acquire Majorana masses through mixing with singlet neutrinos that emerge as composite states of a strongly coupled hidden sector. In this framework, the light neutrinos are partially composite particles that obtain their masses through the inverse seesaw mechanism. We focus on the scenario in which the strong dynamics is approximately conformal in the ultraviolet, and the compositeness scale lies at or below the weak scale. The small parameters in the Lagrangian necessary to realize the observed neutrino masses can naturally arise as a consequence of the scaling dimensions of operators in the conformal field theory. We show that this class of models has interesting implications for a wide variety of experiments, including colliders and beam dumps, searches for lepton flavor violation and neutrinoless double beta decay, and cosmological observations. At colliders and beam dumps, this scenario can give rise to striking signals involving multiple displaced vertices. The exchange of hidden sector states can lead to observable rates for flavor violating processes such as μ → eγ and μ → e conversion. If the compositeness scale lies at or below a hundred MeV, the rate for neutrinoless double beta decay is suppressed by form factors and may be reduced by an order of magnitude or more. The late decays of relic singlet neutrinos can give rise to spectral distortions in the cosmic microwave background that are large enough to be observed in future experiments.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor

Human acidic fibroblast growth factor (hFGF1) is an all beta-sheet protein that is involved in the regulation of key cellular processes including cell proliferation and wound healing. hFGF1 is known to aggregate when subjected to thermal unfolding. In this study, we investigate the equilibrium unfolding of hFGF1 using a wide array of biophysical and biochemical techniques. Systematic analyses of the thermal and chemical denaturation data on hFGF1 variants (Q54P, K126N, R136E, K126N/R136E, Q54P/K126N, Q54P/R136E, and Q54P/K126N/R136E) indicate that nullification of charges in the heparin-binding pocket can significantly increase the stability of wtFGF1. Triple variant (Q54P/K126N/R136E) was found to be the most stable of all the hFGF1 variants studied. With the exception of triple variant, thermal unfolding of wtFGF1 and the other variants is irreversible. Thermally unfolded triple variant refolds completely to its biologically native conformation. Microsecond-level molecular dynamic simulations reveal that a network of hydrogen bonds and salt bridges linked to Q54P, K126N, and R136E mutations, are responsible for the high stability and reversibility of thermal unfolding of the triple variant. In our opinion, the findings of the study provide valuable clues for the rational design of a stable hFGF1 variant that exhibits potent wound healing properties.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Suppression of ion temperature gradient modes by Alfvén activity above a drive threshold in DIII-D

A recent study demonstrates that the suppression of ion temperature gradient (ITG) modes can occur during the nonlinear evolution of toroidicity-induced Alfvén eigenmodes (TAEs) in the DIII-D tokamak [Du et al., Phys. Rev. Lett. 135, 265101 (2025)]. In that work, ITG was suppressed by the formation of a narrow, TAE-induced shear flow layer, whose shearing rate exceeded the ITG decorrelation rate. Here, the shear flow arises from an imbalance between Reynolds and Maxwell stress forces, as the TAE departs from the conventional shear Alfvén wave polarization. This follow-up paper systematically identifies the plasma conditions required for robust ITG suppression through a series of comparative experiments. The results show that TAEs routinely suppress ITG turbulence in plasmas with higher local safety factor (q), elevated fast-ion beta, and larger populations of fast ions on passing orbits, i.e., conditions consistent with the substantial TAE drive. Database analysis further reveals the existence of a threshold in TAE drive for ITG suppression. That is, once the drive exceeds a critical value within a favorable q window, the system undergoes the nonlinear bifurcation process, characterized by a sharp increase in TAE saturated amplitudes at a nearly fixed fast ion drive, suppression of ITG turbulence, and the formation of an internal thermal transport barrier at the localized radii.

Du, X. D. [General Atomics, San Diego, CA (United ↗

Toward Qualifications of HB and LB 650 MHz Cavities for the Prototype Cryomodules for the PIP-II Project

High-beta (HB) and low-beta (LB) 650 MHz cryomodules are key components of the Proton Improvement Plan II (PIP-II) project. In this contribution we present the results of several 5-cell HB650 cavities that have been processed and tested with the purpose of qualifying them for the prototype cryomodule assembly, which will take place later this year. We also present the first results obtained in LB650 single-cell cavities process optimization. Taking advantage of their very similar geometry, we are also analyzing the effect of different surface treatments in FRIB’s 5-cell medium-beta 644MHz cavities. Cavities processed with N-doping and mid-T baking showed very promising results in term of both Q-factors and accelerating gradient for these low-beta structures.

43 PARTICLE ACCELERATORS↗

Atmosphere Explorer observations of the geocoronal H Balmer alpha nightglow

The Balmer alpha nightglow emission of geocoronal atomic hydrogen has been investigated using photometric data obtained by the Visible Airglow Experiment on board the Atmosphere Explorer E satellite. The measured H Balmer alpha intensities are presented as a function of solar depression angle, observation zenith angle, and azimuth relative to the sun for solar minimum conditions. The results are at variance with the earlier D2A satellite observations but in better agreement with previous ground-based studies. As a result of comparison with theoretical predictions, the present observations reaffirm the findings of the ground-based investigations in implying that values for the Lyman beta line center flux are a factor of 2 greater than those derived from direct measurements.

Burrage, M. D.↗

Gibberellin (GA3) enhances cell wall invertase activity and mRNA levels in elongating dwarf pea (Pisum sativum) shoots

The invertase (EC 3.2.1.26) purified from cell walls of dwarf pea stems to homogeneity has a molecular mass of 64 kilodaltons (kD). Poly(A)+RNA was isolated from shoots of dwarf pea plants, and a cDNA library was constructed using lambda gt11 as an expression vector. The expression cDNA library was screened with polyclonal antibodies against pea cell wall invertase. One invertase cDNA clone was characterized as a full-length cDNA with 1,863 base pairs. Compared with other known invertases, one homologous region in the amino acid sequence was found. The conserved motif, Asn-Asp-Pro-Asn-Gly, is located near the N-terminal end of invertase. Northern blot analysis showed that the amount of invertase mRNA (1.86 kb) was rapidly induced to a maximal level 4 h after GA3 treatment, then gradually decreased to the control level. The mRNA level at 4 h in GA3-treated peas was fivefold higher than that of the control group. The maximal increase in activity of pea cell wall invertase elicited by GA3 occcured at 8 h after GA3 treatment. This invertase isoform was shown immunocytochemically to be localized in the cell walls, where a 10-fold higher accumulation occurred in GA3-treated tissue compared with control tissue. This study indicates that the expression of the pea shoot cell-wall invertase gene could be regulated by GA3 at transcriptional and/or translational levels.

NASA Discipline Number 40-50↗