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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 127 records · Page 7

Immunoconjugates: Magic Bullets for Cancer Therapy?

Conjugating cytotoxic agents to antibodies allows for site-specific delivery of the agent to tumor cells and should provide increased efficacy and reduced non-specific toxicity. These site-specific cytotoxic agents are known as immunoconjugates or 'magic bullets' and have demonstrated great promise as therapeutic agents for cancer and other diseases. The historical developments and future potential of this new approach to cancer therapy are reviewed.

Passeri, Daniel R.↗

Piloted simulation of an air-ground profile negotiation process in a time-based Air Traffic Control environment

Historically, development of airborne flight management systems (FMS) and ground-based air traffic control (ATC) systems has tended to focus on different objectives with little consideration for operational integration. A joint program, between NASA's Ames Research Center (Ames) and Langley Research Center (Langley), is underway to investigate the issues of, and develop systems for, the integration of ATC and airborne automation systems. A simulation study was conducted to evaluate a profile negotiation process (PNP) between the Center/TRACON Automation System (CTAS) and an aircraft equipped with a four-dimensional flight management system (4D FMS). Prototype procedures were developed to support the functional implementation of this process. The PNP was designed to provide an arrival trajectory solution which satisfies the separation requirements of ATC while remaining as close as possible to the aircraft's preferred trajectory. Results from the experiment indicate the potential for successful incorporation of aircraft-preferred arrival trajectories in the CTAS automation environment. Fuel savings on the order of 2 percent to 8 percent, compared to fuel required for the baseline CTAS arrival speed strategy, were achieved in the test scenarios. The data link procedures and clearances developed for this experiment, while providing the necessary functionality, were found to be operationally unacceptable to the pilots. In particular, additional pilot control and understanding of the proposed aircraft-preferred trajectory, and a simplified clearance procedure were cited as necessary for operational implementation of the concept.

Williams, David H.↗

The theory of sunspots

This review covers the present state of our theoretical understanding of the physics of sunspots, along with the principal observational results that need to be explained. The topics covered range from the detailed structure of an individual sunspot to the broad connection between sunspots and the global solar magnetic field and the solar cycle. Our aim is to give a critical discussion of the theoretical ideas and models without presenting mathematical details. After outlining the historical development of the basic concepts associated with the magnetohydrodynamic theory of sunspots, we discuss recent treatments of their properties and structure, placing special emphasis on developments that have occurred within the last ten years. There have been remarkable improvements in the theoretical modelling of sunspots, led by new ideas and by more elaborate and realistic numerical simulations. At the same time, new observations have raised new theoretical questions or caused old ones to be reconsidered. In particular, measurements of oscillations in and around sunspots have opened up the new field of sunspot seismology, while recent high-resolution observations have forced us to rethink the structure of a sunspot penumbra.

Thomas, John H.↗

Summary of Airfoil Data

The historical development of NACA airfoils is briefly reviewed. New data are presented that permit the rapid calculation of the approximate pressure distributions for the older NACA four-digit and five-digit airfoils by the same methods used for the NACA 6-series airfoils. The general methods used to derive the basic thickness forms for NACA 6 and 7-series airfoils together with their corresponding pressure distributions are presented. Detail data necessary for the application of the airfoils to wing design are presented in supplementary figures placed at the end of the paper. The report includes an analysis of the lift, drag, pitching-moment, and critical-speed characteristics of the airfoils, together with a discussion of the effects of surface conditions. Available data on high-lift devices are presented. Problems associated with lateral-control devices, leading-edge air intakes, and interference are briefly discussed, together with aerodynamic problems of application. (author)

Abbott, Ira H↗

Diaphragms for Aeronautic Instruments

This investigation was carried out at the request of the National Advisory Committee for Aeronautics and comprises an outline of historical developments and theoretical principles, together with a discussion of expedients for making the most effective use of existing diaphragms actuated by the hydrostatic pressure form an essential element of a great variety instruments for aeronautic and other technical purposes. The various physical data needed as a foundation for rational methods of diaphragm design have not, however, been available hitherto except in the most fragmentary form.

Hersey, M D↗

Nonmetallic Diaphragms for Instruments

This report, the second of a series of reports relating to the general subject of instrument diaphragms. The first report of the series was published as Technical Report no. 165, "diaphragms for aeronautic instruments," and comprised an outline of historical developments and theoretical principles. The present report relates entirely to nonmetallic diaphragms, the use of which in certain types of pressure elements has been increasing for some time. Little, if any, information has been available to aid the designer of instruments using this form of pressure element. It was to attempt to meet the need for such information that the investigation reported in this paper was undertaken. The report describes the various materials which have been used as nonmetallic diaphragms, discusses the factors which affect the performance of the diaphragms and gives the results of tests made for the purpose of investigating the effect produced by these factors.

Eaton, H N↗

X-29: Research Aircraft

A preliminary look at the Ames Dryden Flight Research Center in the context of the X-29 aircraft is provided. The uses of the X-29's 30 deg forward swept wing are examined. The video highlights the historical development of the forward swept wing, and its unique blend of speed, agility, and slow flight potential. The central optimization of the wing, the forward canard, and the rear flaps by an onboard flight computer is also described.

Source record↗

Clementine goes exploring

In early 1994, the US will once again place a spacecraft in lunar orbit. Popularly called Clementine, this spacecraft will spend about two months mapping the Moon and then will travel on to encounter the near-Earth asteroid, 1620 Geographos. A brief description of the historical development of the mission; the lunar survey; Clementine's payload, equipment, and capabilties; and the encounter with Geographos is presented.

Nozette, Stewart↗

The Marshall Engineering Thermosphere (MET) Model: Technical Description - Volume 1

Volume 1 presents a technical description of the Marshall Engineering Thermosphere (MET) model atmosphere and a summary of its historical development. Various programs developed to augment the original capability of the model are discussed in detail. The report also describes each of the individual subroutines developed to enhance the model. Computer codes for these subroutines are contained in four appendices.

Smith, R. E.↗

Laser Materials Processing for NASA's Aerospace Structural Materials

Lasers are useful for performing operations such as joining, machining, built-up freeform fabrication, and surface treatment. Due to the multifunctional nature of a single tool and the variety of materials that can be processed, these attributes are attractive in order to support long-term missions in space. However, current laser technology also has drawbacks for space-based applications. Specifically, size, power efficiency, lack of robustness, and problems processing highly reflective materials are all concerns. With the advent of recent breakthroughs in solidstate laser (e.g., diode-pumped lasers) and fiber optic technologies, the potential to perform multiple processing techniques in space has increased significantly. A review of the historical development of lasers from their infancy to the present will be used to show how these issues may be addressed. The review will also indicate where further development is necessary to realize a laser-based materials processing capability in space. The broad utility of laser beams in synthesizing various classes of engineering materials will be illustrated using state-of-the art processing maps for select lightweight alloys typically found on spacecraft. Both short- and long-term space missions will benefit from the development of a universal laser-based tool with low power consumption, improved process flexibility, compactness (e.g., miniaturization), robustness, and automation for maximum utility with a minimum of human interaction. The potential advantages of using lasers with suitable wavelength and beam properties for future space missions to the moon, Mars and beyond will be discussed. The laser processing experiments in the present report were performed using a diode pumped, pulsed/continuous wave Nd:YAG laser (50 W max average laser power), with a 1064 nm wavelength. The processed materials included Ti-6AI-4V, Al-2219 and Al-2090. For Phase I of this project, the laser process conditions were varied and optimized to see the effects on melt-quenching, cladding/alloying (using the pre-placed powder technique), and cutting. Key parameters such laser power, pulse repetition frequency, process speed, and shield gas flow and the observed process characteristics such as plasma formation during laser/material interaction, have been reported for all experimental runs. Preliminary materials characterization of select samples was carried out using various microscopy, diffraction, spectroscopy and microhardness test methods, and reported. Select nitridation results of Ti-6AI-4V using nitrogen assist gas indicated the successful formation of hard titanium nitrides with much higher hardness (2180 kg/sq mm). A cost-effective and simple powder delivery system has been successfully fabricated for the further experimentation in Phase H.

Nagarathnam, Karthik↗

Adventures with Implicit Methods

In this lecture we trace the historical developments of alternating direction implicit methods. In particular, we emphasize contributions originating in the Computational Fluid Dynamics Branch at Ames Research Center in the 1970's and early 1980's. Joe Steger played a seminal role in demonstrating the practicality of using an efficient, vectorized, implicit code for solving the compressible Navier-Stokes equations. Numerous discussions with Joe had a significant impact on our own research and it is a pleasure to dedicate this lecture to honor his memory.

Warming, Robert F.↗

Atmospheric Models for Engineering Applications

This paper will review the historical development of reference and standard atmosphere models and their applications. The evolution of the U.S. Standard Atmosphere will be addressed, along with the Range Reference Atmospheres and, in particular, the NASA Global Reference Atmospheric Model (GRAM). The extensive scope and content of the GRAM will be addressed since it represents the most extensive and complete 'Reference' atmosphere model in use today. Its origin was for engineering applications and that remains today as its principal use.

Johnson, Dale L.↗

Electrical double layers at the oil/water interface

This review presents the historical development and current status of the theory of the electrical double layer at a liquid/liquid interface. It gives rigorous thermodynamic definitions of all basic concepts related to liquid interfaces and to the electrical double layer. The difference between the surface of a solid electrode and the interface of two immiscible electrolyte solutions (ITIES) is analyzed in connection to their electrical properties. The most important classical relationships for the electrical double layer are presented and critically discussed. The generalized adsorption isotherm is derived. After a short review of the classical Gouy-Chapman and Verwey-Niessen models, more recent developments of the double layer theory are presented. These include effects of variable dielectric permittivity, nonlocal electrostatics, hydration forces, the modified Poisson-Boltzmann equation and the ion-dipole plasma. The relative merits of different theories are estimated by comparing them with computer simulation of the ITIES and electrical double layer. Special attention is given to the structure of ITIES and its variation due to adsorption of ions and amphiphilic molecules.

Non-NASA Center↗

Laser Velocimetry: The Elusive Third Component

The historical development of techniques for measuring three velocity components using laser velocimetry is presented. The techniques are described and their relative merits presented. Many of the approaches currently in use based on the fringe laser velocimeter have yielded inaccurate measurements of turbulence intensity in the on-axis component. A possible explanation for these inaccuracies is presented along with simulation results.

Meyers, James F.↗

The Elusive Third Component

The historical development of techniques for measuring three velocity components using laser velocimetry is presented. The techniques are described and their relative merits presented. Many of the approaches currently in use based on the fringe laser velocimeter have yielded inaccurate measurements of turbulence intensity in the on-axis component. A possible explanation for these inaccuracies is presented along with simulation results.

Meyers, James F.↗

Review of Tm and Ho Materials; Spectroscopy and Lasers

A review of Tm and Ho materials is presented, covering some fundamental aspects on the spectroscopy and laser dynamics in both single and co-doped systems. Following an introduction to 2- m lasers, applications and historical development, the physics of quasi-four level lasers, energy transfer and modeling are discussed in some detail. Recent developments in using Tm lasers to pump Ho lasers are discussed, and seen to offer some advantages over conventional Tm:Ho lasers. This article is not intended as a complete review, but as a primer for introducing concepts and a resource for further study.

Walsh, Brian M.↗

Remote Sensing

Remote sensing is one of a suite of geospatial technologies that are having a growing impact in a wide variety of areas from commerce to science to public policy. The field of remote sensing evolved from the interpretation of aerial photographs to the analysis of satellite imagery, and from local area studies to global analyses, with advances in sensor system technologies and digital computing. Today remote sensor systems can provide data from energy emitted, reflected, and/or transmitted from all parts of the electromagnetic spectrum. Examples of applications of these data include population and demography studies, study of archaeological sites, energy studies using hydrological models, urban planning, environmental monitoring, environments, treaty enforcement, land use/land cover planning, weather forecasting, and agricultural production estimation, just to name a few. The material that follows provides a brief overview of the historical development of remote sensing, emphasizing the increasing complexity of platforms, systems, and tasks.

electromagnetic spectrum↗