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At least 127 records · Page 7

The aerodynamic characteristics of airfoils at negative angles of attack

A number of airfoils, including 14 commonly used airfoils and 10 NACA airfoils, were tested through the negative angle-of-attack range in the NACA variable-density wind tunnel at a Reynolds Number of approximately 3,000,000. The tests were made to supply data to serve as a basis for the structural design of airplanes in the inverted flight condition. In order to make the results immediately available for this purpose they are presented herein in preliminary form, together with results of previous tests of the airfoils at positive angles of attack. An analysis of the results made to find the variation of the ratio of the maximum negative lift coefficient to the maximum positive lift coefficient led to the following conclusions: 1) For airfoils of a given thickness, the ratio -C(sub L max) / +C(sub L max) tends to decrease as the mean camber is increased. 2) For airfoils of a given mean camber, the ratio -C(sub L max) / +C(sub L max) tends to increase as the thickness increases.

Anderson, Raymond F↗

Experimental Verification of the Rudder-Free Stability Theory for an Airplane Model Equipped with Rudders Having Negative Floating Tendency and Negligible Friction

An investigation has been made in the Langley free-flight tunnel to obtain an experimental verification of the theoretical rudder-free stability characteristics of an airplane model equipped with conventional rudders having negative floating tendencies and negligible friction. The model used in the tests was equipped with a conventional single vertical tail having rudder area 40 percent of the vertical tail area. The model was tested both in free flight and mounted on a strut that allowed freedom only in yaw. Tests were made with three different amounts of rudder aerodynamic balance and with various values of mass, moment of inertia, and center-of-gravity location of the rudder. Most of the stability derivatives required for the theoretical calculations were determined from forced and free-oscillation tests of the particular model tested. The theoretical analysis showed that the rudder-free motions of an airplane consist largely of two oscillatory modes - a long-period oscillation somewhat similar to the normal rudder-fixed oscillation and a short-period oscillation introduced only when the rudder is set free. It was found possible in the tests to create lateral instability of the rudder-free short-period mode by large values of rudder mass parameters even though the rudder-fixed condition was highly stable. The results of the tests and calculation indicated that for most present-day airplanes having rudders of negative floating tendency, the rudder-free stability characteristics may be examined by simply considering the dynamic lateral stability using the value of the directional-stability parameter Cn(sub p) for the rudder-free condition in the conventional controls-fixed lateral-stability equations. For very large airplanes having relatively high values of the rudder mass parameters with respect to the rudder aerodynamic parameters, however, analysis of the rudder-free stability should be made with the complete equations of motion. Good agreement between calculated and measured rudder-free stability characteristics was obtained by use of the general rudder-free stability theory, in which four degrees of lateral freedom are considered. When this assumption is made that the rolling motions alone or the lateral and rolling motions may be neglected in the calculations of rudder-free stability, it is possible to predict satisfactorily the characteristics of the long-period (Dutch roll type) rudder-free oscillation for airplanes only when the effective-dihedral angle is small. With these simplifying assumptions, however, satisfactory prediction of the short-period oscillation may be obtained for any dihedral. Further simplification of the theory based on the assumption that the rudder moment of inertia might be disregarded was found to be invalid because this assumption made it impossible to calculate the characteristics of the short-period oscillations.

STABILITY- FAIRCHILD R2K-1↗

Ion Accelerator With Negatively Biased Decelerator Grid

Three-grid ion accelerator in which accelerator grid is biased at negative potential and decelerator grid downstream of accelerator grid biased at smaller negative potential. This grid and bias arrangement reduces frequency of impacts, upon accelerator grid, of charge-exchange ions produced downstream in collisions between accelerated ions and atoms and molecules of background gas. Sputter erosion of accelerator grid reduced.

Brophy, John R.↗

Countermeasure for reducing post-flight orthostatic intolerance: Lower Body Negative Pressure (LBNP) experiment E140

Investigators have shown that after 1-2 weeks of bed rest ingestion of 1000 ml of a salt water solution during 4 hours of continuous exposure to 30 mm Hg of lower body negative pressure will protect plasma volume and orthostatic function for up to 24 hours. We hypothesize that a similar countermeasure will reduce the effects of fluid loss induced by headward fluid shift during space flight. The objective of this flight experiment is to evaluate the efficacy of the proposed countermeasure in reversing these effects on the cardiovascular system. Lower Body Negative Pressure (LBNP) involves exposing the legs and lower abdomen to reduced air pressure. The LBNP device is an air-tight chamber that seals the subject's waist to enclose the lower body. As used in this experiment, LBNP provides both the candidate treatment as well as the means of assessing the effectiveness of the treatment.

Charles, John B.↗

A future, intense source of negative hydrogen ions

By directly heating lithium hydride in a vacuum, up to 18 micro-A/sq cm of negative hydrogen has been obtained from the crystal lattice. The amount of ion current extracted and analyzed is closely related to the temperature of the sample and to the rate at which the temperature is changed. The ion current appears to be emission limited and saturates with extraction voltage. For a fixed extraction voltage, the ion current could be maximized by placing a grid between the sample surface and the extraction electrode. Electrons accompanying the negative ions were removed by a magnetic trap. A Wein velocity filter was designed and built to provide definitive mass analysis of the extracted ion species. This technique when applied to other alkali hydrides may produce even higher intensity beams possessing low values of emittance.

Siefken, Hugh↗

Changes in left ventricular function as determined by the multi-wire gamma camera at near presyncopal levels of lower body negative pressure

At presyncopal levels of lower body negative pressure (LBNP), we have frequently observed electrocardiographic responses that may be due to changes in cardiac position and/or shape, but could be indicative of altered myocardial function. To further investigate this, we evaluated cardiac function using a nuclear imaging technique in 21 healthy subjects (17 men and 4 women) after 30 minutes of supine rest and near the end of a presyncopal-limited LBNP exposure (LBNP averaged 65 plus or minus 3 mmHg at injection). Cardiac first pass images were obtained with a Multi-Wire Gamma Camera following an intravenous bolus injection of 30-50 millicurries of Tantalum-178. Manual blood pressures and electrocardiograms were obtained throughout the 3 minute graded LBNP protocol. Between rest and injection during LBNP, heart rate increased (P less than 0.01) from 67 plus or minus 3 beats per minute to 99 plus or minus beats per minute, systolic blood pressure decreased (P less than 0.01) from 110 plus or minus 3 mmHg to 107 plus or minus 3 mmHg and left ventricular ejection fraction (EF) decreased (P less than 0.01) from 0.57 plus or minus 0.02 to 0.48 plus or minus 0.02. During LBNP, ST segment depression of at least 0.5 mm occurred in 7 subjects. Subjects with ST depression had greater reductions (P = 0.05) in EF than subjects without ST depression (0.15 plus or minus 0.07 versus 0.005 plus or minus 0.03), but also tolerated greater levels (P less than 0.05) of negative pressure (88 plus or minus mmHg versus 69 plus or minus 5 mmHg). There was a significant relationship between presyncopal LBNP level and EF (R(exp 2) = 0.50, P less than 0.05). Our findings suggest there may be a decrease in systolic myocardial function at high levels of LBNP.

Pintner, R.↗

Periodic upright posture negates the suppression of neuroendocrine response to head down bedrest

Head down bedrest (HDT) decreases plasma neurohormone levels, attaining a nadir within four hours. The present study evaluates the effect of periodic standing or exercises (+G(z)) on this acute suppression of plasma neurohormones. Methods: Nine male subjects (mean plus or minus SE age 37 plus or minus 2 yr; height 182 plus or minus 2 cm; weight 83 plus or minus 3 kg) were admitted to the Human Research Facility on three occasions separated by one month. Subjects were assigned to head down tilt (minus 6 degrees) or 15-minutes of standing or moderate exercise at the end of each hour. Initially during an ambulatory period, subjects were placed in a supine position for 45-min and a control blood sample obtained. The next day following 4 hours of HDT with or without standing or exercise a blood sample was taken 45-min (3 3/4 hours into HDT) after the preceding stand or exercise. Blood was withdrawn and all plasma samples frozen for determination of neurohormone levels within the same assay. Plasma aldosterone, Plasma Renin Activity (PRA) vasopressin (AVP) and cortisol levels were measured by radioimmunoassay. Norepinephrine (NE) and epinephrine (E) levels were measured by electrochemical detection following HPLC. Values were compared by ANOVA, P less than 0.05. Results: Control levels following 45-min supine were not different between treatments. HDT suppressed plasma aldosterone (13.9 plus or minus 3.7 to 6.6 plus or minus 0.7 ng/dl) and NE levels (299 plus or minus 35 to 217 plus or minus 23 pg/dl), E (69 plus or minus 15 to 65 plus or minus 21 pg/ml), and PRA (0.64 plus or minus 0.13 to 0.58 plus or minus 0.17 ngAl/m/hr) were not significantly altered. Standing or exercise negated the decrease in aldosterone and NE levels due to HDT. Conclusions: Periodic upright posture (+G(z)) with or without exercise for 15-min out of each hour negates the acute suppression of aldosterone and NE associated with HDT.

Wade, C. E.↗

Negative Electron Affinity Effect on the Surface of Chemical Vapor Deposited Diamond Polycrystalline Films

Strong negative electron affinity effects have been observed on the surface of as-grown chemical vapor deposited diamond using Secondary Electron Emission. The test samples were randomly oriented and the surface was terminated with hydrogen. The effect appears as an intensive peak in the low energy part of the spectrum of the electron energy distribution and may be described in the model of effective negative electron affinity.

Krainsky, I. L.↗

A Wind-Tunnel Investigation of the Stall-Flutter Characteristics of a Supersonic-Type Propeller at Positive and Negative Thrust

An investigation has been made utilizing a three-blade, 10-foot- diameter, supersonic-ty-pe propeller to determine propeller flutter characteristics. The particular flutter characteristics of interest were (1) the effect of stall flutter on a propeller operating in positive and negative thrust, (2) the effect of stall flutter on a propeller operating with the thrust axis inclined, and (3) the variation of vibratory blade shear stresses as the stall flutter boundary is penetrated and exceeded. Thrust and power measurements were made for all test conditions. Wake and inflow surveys were made when appropriate, to define the thrust and torque distributions and the magnitude of the inflow velocity. Stress measurements were made simultaneously to obtain the propeller flutter and bending response. It was found when operating both in the positive and negative thrust regions that, for most cases after the onset of flutter, the magnitude of the flutter stresses at first increased rapidly with section blade angle P, after which further increases in 0 resulted in only a moderate increase or a reduction in stress. Thrust-axis inclination up to the limit of the tests (angle of attack of 15 deg and dynamic pressure of 40 psf) appeared to have no effect on stall flutter. The stall flutter stresses were found to be directly associated with the section thrust characteristics of the blades. The onset of flutter was found to occur simultaneously with the divergence of the section thrust variation with blade angle from linearity for stations outboard of the blade 0.8-radius station. The maximum flutter stresses appeared to be a function of the maximum section thrust obtained at or in the vicinity of the blade 0.8-radius station. In an attempt to correlate two-dimensional airfoil data with three-dimensional data to predict the stall angle of attack (divergence of the section thrust) of the blade sections, it was found that no consistent correlation could be obtained. Also, a knowledge of the inflow conditions appeared to be insufficient to account for differences in airfoil characteristics between the two-dimensional and the three-dimensional cases.

Rogallo, Vernon L.↗

Negative Electron Affinity Mechanism for Diamond Surfaces

The energy distribution of the secondary electrons for chemical vacuum deposited diamond films with Negative Electron Affinity (NEA) was investigated. It was found that while for completely hydrogenated diamond surfaces the negative electron affinity peak in the energy spectrum of the secondary electrons is present for any energy of the primary electrons, for partially hydrogenated diamond surfaces there is a critical energy above which the peak is present in the spectrum. This critical energy increases sharply when hydrogen coverage of the diamond surface diminishes. This effect was explained by the change of the NEA from the true type for the completely hydrogenated surface to the effective type for the partially hydrogenated surfaces.

Krainsky, I. L.↗

Markstein Numbers of Negatively-Stretched Premixed Flames: Microgravity Measurements and Computations

The effect of flame stretch, composed of strain and curvature, plays a major role in the propagation of turbulent premixed flames. Although all forms of stretch (positive and negative) are present in turbulent conditions, little research has been focused on the stretch due to curvature. The present study quantifies the Markstein number (which characterizes the sensitivity of the flame propagation speed to the imposed stretch rate) for an inwardly-propagating flame (IPF). This flame is of interest because it is negatively stretched, and is subjected to curvature effects alone, without the competing effects of strain. In an extension of our previous work, microgravity experiments were run using a vortex-flame interaction to create a pocket of reactants surrounded by an IPF. Computations using the RUN-1DL code of Rogg were also performed in order to explain the measurements. It was found that the Markstein number of an inwardly-propagating flame, for both the microgravity experiment and the computations, is significantly larger than that of an outwardly-propagating flame. Further insight was gained by running the computations for the simplified (hypothetical) cases of one step chemistry, unity Lewis number, and negligible heat release. Results provide additional evidence that the Markstein numbers associated with strain and curvature have different values.

Ibarreta, Alfonso F.↗

Biochemical and functional analysis of CTR1, a protein kinase that negatively regulates ethylene signaling in Arabidopsis

CTR1 encodes a negative regulator of the ethylene response pathway in Arabidopsis thaliana. The C-terminal domain of CTR1 is similar to the Raf family of protein kinases, but its first two-thirds encodes a novel protein domain. We used a variety of approaches to investigate the function of these two CTR1 domains. Recombinant CTR1 protein was purified from a baculoviral expression system, and shown to possess intrinsic Ser/Thr protein kinase activity with enzymatic properties similar to Raf-1. Deletion of the N-terminal domain did not elevate the kinase activity of CTR1, indicating that, at least in vitro, this domain does not autoinhibit kinase function. Molecular analysis of loss-of-function ctr1 alleles indicated that several mutations disrupt the kinase catalytic domain, and in vitro studies confirmed that at least one of these eliminates kinase activity, which indicates that kinase activity is required for CTR1 function. One missense mutation, ctr1-8, was found to result from an amino acid substitution within a new conserved motif within the N-terminal domain. Ctr1-8 has no detectable effect on the kinase activity of CTR1 in vitro, but rather disrupts the interaction with the ethylene receptor ETR1. This mutation also disrupts the dominant negative effect that results from overexpression of the CTR1 amino-terminal domain in transgenic Arabidopsis. These results suggest that CTR1 interacts with ETR1 in vivo, and that this association is required to turn off the ethylene-signaling pathway.

Non-NASA Center↗

Is it really so bad? A comparison of positive and negative experiences in Antarctic winter stations

This study examined the range of positive and negative themes reported by 104 Australian Antarctic winter personnel at four stations during two austral winters. Reports from the expeditioners were subjected to a content analysis using the TextSmart software from SPSS, Inc. Results indicated that, although the list of negative experiences is lengthy, most events are relatively rare. On the other hand, although the list of positive experiences is short, the frequencies with which they are reported are much greater than for most of the problems. Possible explanations for these themes and for future directions are discussed.

NASA Discipline Space Human Factors↗

Macrophage cell lines derived from major histocompatibility complex II-negative mice

Two bone-marrow-derived macrophage cell lines, C2D and C2Dt, were isolated from major histocompatibility class II negative knock-out mice. The C2D cell line was stabilized by continuous culture in colony-stimulating factor-1 and the C2Dt cell line was transformed with SV40 virus large T antigen. These cells exhibited phenotypic properties of macrophages including morphology and expression of Mac 1 and Mac 2 cell surface molecules. These cells also had comparable growth to the bone-marrow-derived macrophage cell line B6MP102. These new cell lines were not spontaneously cytotoxic and were only capable of modest killing of F5b tumor cells when stimulated with LPS and interferon-gamma, but not when stimulated with LPS alone or with staphylococcal exotoxin. C2D and C2Dt cells phagocytosed labeled Staphylococcus aureus similarly to B6MP102 cells but less well than C2D peritoneal macrophages. These cell lines secreted interleukin-6, but not tumor necrosis factor or nitric oxide in response to LPS or staphlococcal enterotoxins A or B C2D(t) cells were tumorigenic in C2D and C57BL/6J mice but C2D cells were not. These data suggest that macrophage cell lines can be established from bone marrow cells of major histocompatibility complex II-negative mice.

NASA Discipline Musculoskeletal↗

Negative regulators of cell proliferation

Cell proliferation is governed by the influence of both mitogens and inhibitors. Although cell contact has long been thought to play a fundamental role in cell cycling regulation, and negative regulators have long been suspected to exist, their isolation and purification has been complicated by a variety of technical difficulties. Nevertheless, over recent years an ever-expanding list of putative negative regulators have emerged. In many cases, their biological inhibitory activities are consistent with density-dependent growth inhibition. Most likely their interactions with mitogenic agents, at an intracellular level, are responsible for either mitotic arrest or continued cell cycling. A review of naturally occurring cell growth inhibitors is presented with an emphasis on those factors shown to be residents of the cell surface membrane. Particular attention is focused on a cell surface sialoglycopeptide, isolated from intact bovine cerebral cortex cells, which has been shown to inhibit the proliferation of an unusually wide range of target cells. The glycopeptide arrest cells obtained from diverse species, both fibroblasts and epithelial cells, and a broad variety of transformed cells. Signal transduction events and a limited spectrum of cells that are refractory to the sialoglycopeptide have provided insight into the molecular events mediated by this cell surface inhibitor.

Review↗

Evaluation of Treadmill Exercise in a Lower Body Negative Pressure Chamber as a Countermeasure for Weightlessness-Induced Bone Loss: a Bed Rest Study with Identical Twins

Counteracting bone loss is required for future space exploration. We evaluated the ability of treadmill exercise in a LBNP chamber to counteract bone loss in a 30-day bed rest study. Eight pairs of identical twins were randomly assigned to sedentary control or exercise groups. Exercise within LBNP decreased the bone resorption caused by bed rest and may provide a countermeasure for spaceflight. INTRODUCTION: Bone loss is one of the greatest physiological challenges for extended-duration space missions. The ability of exercise to counteract weightlessness-induced bone loss has been studied extensively, but to date, it has proven ineffective. We evaluated the effectiveness of a combination of two countermeasures-treadmill exercise while inside a lower body negative pressure (LBNP) chamber-on bone loss during a 30-day bed rest study. MATERIALS AND METHODS: Eight pairs of identical twins were randomized into sedentary (SED) or exercise/LBNP (EX/LBNP) groups. Blood and urine samples were collected before, several times during, and after the 30-day bed rest period. These samples were analyzed for markers of bone and calcium metabolism. Repeated measures ANOVA was used to determine statistical significance. Because identical twins were used, both time and group were treated as repeated variables. RESULTS: Markers of bone resorption were increased during bed rest in samples from sedentary subjects, including the collagen cross-links and serum and urinary calcium concentrations. For N-telopeptide and deoxypyridinoline, there were significant (p < 0.05) interactions between group (SED versus EX/LBNP) and phase of the study (sample collection point). Pyridinium cross-links were increased above pre-bed rest levels in both groups, but the EX/LBNP group had a smaller increase than the SED group. Markers of bone formation were unchanged by bed rest in both groups. CONCLUSIONS: These data show that this weight-bearing exercise combined with LBNP ameliorates some of the negative effects of simulated weightlessness on bone metabolism. This protocol may pave the way to counteracting bone loss during spaceflight and may provide valuable information about normal and abnormal bone physiology here on Earth.

Twin Study↗

Potential Carbon Negative Commercial Aviation through Land Management

Brazilian terra preta soil and char-enhanced soil agricultural systems have demonstrated both enhanced plant biomass and crop yield and functions as a carbon sink. Similar carbon sinking has been demonstrated for both glycophyte and halophyte plants and plant roots. Within the assumption of 3.7 t-C/ha/yr soils and plant root carbon sinking, it is possible to provide carbon neutral U.S. commercial aviation using about 8.5% of U.S. arable lands. The total airline CO2 release would be offset by carbon credits for properly managed soils and plant rooting, becoming carbon neutral for carbon sequestered synjet processing. If these lands were also used to produce biomass fuel crops such as soybeans at an increased yield of 60 bu/acre (225gal/ha), they would provide over 3.15 10(exp 9) gallons biodiesel fuel. If all this fuel were refined into biojet it would provide a 16% biojet-84% synjet blend. This allows the U.S. aviation industry to become carbon negative (carbon negative commercial aviation through carbon credits). Arid land recovery could yield even greater benefits.

Hendricks, Robert C.↗

A Benign, Low Z Electron Capture Agent for Negative Ion TPCs

We have identified nitromethane (CH3NO2) as an effective electron capture agent for negative ion TPCs (NITPCs). We present drift velocity and longitudinal diffusion measurements for negative ion gas mixtures using nitromethane as the capture agent. Not only is nitromethane substantially more benign than the only other identified capture agent, CS2, but its low atomic number will enable the use of the NITPC as a photoelectric X-ray polarimeter in the 1-10 keV band.

Martoff, C. J.↗