Hydrogen Refueling Reference Station Lot Size Analysis for Urban Sites.
Abstract not provided.
Ehrhart, Brian David↗
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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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An Adaptive Reference Scheme to Extend the Functional Range of Optical Backscatter Reflectometry in Extreme Environments
Optical frequency domain reflectometry (OFDR) measurements are performed by recording the interference pattern of light backscattered by density fluctuations or Bragg gratings along the length of an optical fiber. Changes in local temperature or strain in the fiber cause shifts in the backscattered light spectrum, which can be calibrated to the applied temperature or strain. Comparing the backscattered optical spectra from each reflection site with a reference (unstrained) spectrum allows for quantification of local spectral shifts. While mature OFDR-based technologies can provide high-precision spatially distributed measurements over kilometer lengths, the post-processing approaches used to recover spectral shifts from raw optical intensity data can limit the use of OFDR in harsh environments. This paper presents a novel approach to post-processing OFDR data which extends the usability of optical fibers exposed to harsh environments. This approach is the first to use the spectral shift quality, calculated for two OFDR measurements, to identify an appropriate reference scan from which the spectral shift can be determined. Here, three experimental data sets are used to test the algorithm: (1) an optical fiber heated to >950°C, (2) an aluminum-embedded optical fiber under strain from differential thermal expansion, and (3) an optical fiber exposed to a total neutron flux of 2×10 13 n/cm 2 /s over 40 hours in a nuclear test reactor. Results show that using a metric of quality to select an appropriate reference measurement extends the functional range of OFDR strain and temperature sensors. Furthermore, this algorithm can be applied to existing OFDR data.
47 OTHER INSTRUMENTATION↗
Calendar Year 2024 Underground Test Area Annual Sampling Letter Report, Nevada National Security Site, Nevada, Rev. 1
The Underground Test Area (UGTA) Sampling Plan for Corrective Action Units (CAUs) 101 and 102: Central and Western Pahute Mesa, Nevada National Security Site (NNSS), Nevada (referred to herein as “the Plan”) (DOE/EMNV, 2025) describes the approach for collecting and analyzing groundwater samples to meet the objectives of the U.S. Department of Energy (DOE), Environmental Management (EM) Nevada Program’s UGTA Activity. The Plan is designed to ensure compliance with the UGTA Quality Assurance Plan (QAP) (DOE/EMNV, 2024), and the Federal Facility Agreement and Consent Order (FFACO) (1996, as amended).
54 ENVIRONMENTAL SCIENCES↗
Evaluation of Spaceborne L-band Radiometer Measurements for Terrestrial Freeze/Thaw Retrievals in Canada
The landscape freeze/thaw (FT) state has an important impact on the surface energy balance, carbon fluxes, and hydrologic processes; the timing of spring melt is linked to active layer dynamics in permafrost areas. L-band (1.4 GHz) microwave emission could allow the monitoring of surface state dynamics due to its sensitivity to the pronounced permittivity difference between frozen and thawed soil. The aim of this paper is to evaluate the performance of both Aquarius and Soil Moisture and Ocean Salinity (SMOS) L-band passive microwave measurements using a polarization ratio-based algorithm for landscape FT monitoring. Weekly L-band satellite observations are compared with a large set of reference data at 48 sites across Canada spanning three environments: tundra, boreal forest, and prairies. The reference data include in situ measurements of soil temperature (Tsoil) and air temperature (Tair), and Moderate Resolution Imaging Spectroradiometer (MODIS) land surface temperature (LST) and snow cover area (SCA) products. Results show generally good agreement between Lband FT detection and the surface state estimated from four reference datasets. The best apparent accuracies for all seasons are obtained using Tair as the reference. Aquarius radiometer 2 (incidence angle of 39.6) data gives the best accuracies (90.8), while for SMOS the best results (87.8 of accuracy) are obtained at higher incidence angles (55- 60). The FT algorithm identifies both freeze onset and end with a delay of about one week in tundra and two weeks in forest and prairies, when compared to Tair. The analysis shows a stronger FT signal at tundra sites due to the typically clean transitions between consistently frozen and thawed conditions (and vice versa) and the absence of surface vegetation. Results in the prairies were poorer because of the influence of vegetation growth in summer (which decreases the polarization ratio) and the high frequency of ephemeral thaw events during winter. Freeze onset and end maps created from the same algorithm applied to SMOS and Aquarius measurements characterize similar FT patterns over Canada. This study shows the potential of using L-band spaceborne observations for FT monitoring, but underlines some limitations due to ice crusts in the snowpack, liquid water content in snow cover during the spring freeze to thaw transition, and vegetation growth.
soil freeze/thaw↗
Standard Reference Rainfall Products Used in the TRMM Ground Efforts
The Primary goal of the Tropical Rainfall Measuring Mission (TRMM) Ground Validation (GV) effort is to provide basic validation of satellite-derived precipitation measurements over monthly climatologies. To this end, the Joint Center for Earth Systems Technology (JCET) at the University of Maryland, Baltimore County produces monthly rainfall accumulation reference products for each of the four primary TRMM GV sites. These products, standard methodology for deriving monthly, gauge-adjusted rainfall products, are utilized for each primary site. The monthly rainfall GV reference products are developed in discrete, modular steps with distinct intermediate products. These developmental steps, which will be fully discussed, include: (1) extracting radar data over locations of rain gauges, (2) merging rain gauge and radar data in time and space with user-defined options, (3) quality control of radar and gauge merged data by tracking accumulations from each instrument, and (4) deriving Z_R relationship from quality-controlled merged data over monthly time scales. A summary of all gauge statistics and GV rainfall reference products available for TRMM science users will be presented. Basic reference product results and trends involving monthly accumulation, Z-R relationship, and gauge statistics for primary GV site will be discussed. Finally, the sample impact on monthly rainfall reference products, through varying the time interval between intermediate rainfall accumulations, will be analyzed and presented.
Marks, David A.↗
A biophysical framework for double-drugging kinases
Selective orthosteric inhibition of kinases has been challenging due to the conserved active site architecture of kinases and emergence of resistance mutants. Simultaneous inhibition of distant orthosteric and allosteric sites, which we refer to as “double-drugging”, has recently been shown to be effective in overcoming drug resistance. However, detailed biophysical characterization of the cooperative nature between orthosteric and allosteric modulators has not been undertaken. Here, we provide a quantitative framework for double-drugging of kinases employing isothermal titration calorimetry, Förster resonance energy transfer, coupled-enzyme assays, and X-ray crystallography. We discern positive and negative cooperativity for Aurora A kinase (AurA) and Abelson kinase (Abl) with different combinations of orthosteric and allosteric modulators. We find that a conformational equilibrium shift is the main principle governing cooperativity. Notably, for both kinases, we find a synergistic decrease of the required orthosteric and allosteric drug dosages when used in combination to inhibit kinase activities to clinically relevant inhibition levels. X-ray crystal structures of the double-drugged kinase complexes reveal the molecular principles underlying the cooperative nature of double-drugging AurA and Abl with orthosteric and allosteric inhibitors. Finally, we observe a fully closed conformation of Abl when bound to a pair of positively cooperative orthosteric and allosteric modulators, shedding light on the puzzling abnormality of previously solved closed Abl structures. Collectively, our data provide mechanistic and structural insights into rational design and evaluation of double-drugging strategies.
59 BASIC BIOLOGICAL SCIENCES↗
Integrase-On-Demand-Pipeline Data Set
Files needed to run the Integrase-On-Demand-Pipeline, a program designed to provide users with a list of putative attachment site and integrase pairs for a prokaryotic genome of interest. isles.pkl: Serialized python-object file, containing a dictionary of attachment site sequences and reference genomic island information extracted from the Genomic island database ints.gff: Gene format file containing annotations for all integrases referenced in isles.pkl. The source genome, gene coordinates, integrase name, protein IDs and amino acid sequence included. reps.msh: Binary file containing 1000 128-bit MurmurHash3 hashes for >80,000 genomes
McClain, Hannah Marie [Sandia National Laboratorie↗
Investigating effects of soil chemicals on density of small mammal bioindicators using spatial capture-recapture models
Monitoring the ecological impacts of environmental pollution and the effectiveness of remediation efforts requires identifying relationships between contaminants and the disruption of biological processes in populations, communities, or ecosystems. Wildlife are useful bioindicators, but traditional comparative experimental approaches rely on a staunch and typically unverifiable assumption that, in the absence of contaminants, reference and contaminated sites would support the same densities of bioindicators, thereby inferring direct causation from indirect data. We demonstrate the utility of spatial capture-recapture (SCR) models for overcoming these issues, testing if community density of common small mammal bioindicators was directly influenced by soil chemical concentrations. By modeling density as an inhomogeneous Poisson point process, we found evidence for an inverse spatial relationship between Peromyscus density and soil mercury concentrations, but not other chemicals, such as polychlorinated biphenyls, at a site formerly occupied by a nuclear reactor. Although the coefficient point estimate supported Peromyscus density being lower where mercury concentrations were higher (β = –0.44), the 95% confidence interval overlapped zero, suggesting no effect was also compatible with our data. Estimated density from the most parsimonious model (2.88 mice/ha; 95% CI = 1.63–5.08), which did not support a density-chemical relationship, was within the range of reported densities for Peromyscus that did not inhabit contaminated sites elsewhere. Environmental pollution remains a global threat to biodiversity and ecosystem and human health, and our study provides an illustrative example of the utility of SCR models for investigating the effects that chemicals may have on wildlife bioindicator populations and communities.
36 MATERIALS SCIENCE↗
Motorcycle Safety Committee [Slides]
This is a presentation to be sent to various DOE sites as a reference for LANL's Motorcycle Safety Committee and includes how to start and sustain a safety committee and organize events. Examples from LANL's program are included. Contacts from Los Alamos National Lab, Lawrence Livermore National Lab, and Idaho National Lab are provided.
96 KNOWLEDGE MANAGEMENT AND PRESERVATION↗
Use Restriction (UR) Update Activity, Groups 23 and 31 URs Proposed for Downgrade or Removal
A White Paper document containing background information, rationale, and conclusion as justification for the downgrade or removal of use restrictions from various FFACO Corrective Action Sites (CASs) and their associated Corrective Action Units (CAUs) at the Nevada National Security Site (NNSS) [previously Nevada Test Site (NTS), as referred to throughout the white paper].
54 ENVIRONMENTAL SCIENCES↗
Site G - Atmospheric Sensor / Reviewed Data
This dataset contains meteorological measurements including temperature, pressure, and relative humidity at multiple heights deployed on tethered balloon system at AWAKEN site G. Z07 refers to the seventh height position of the iMet-XQ2 mounted on the tethered balloon.
17 WIND ENERGY↗
Site G - Atmospheric Sensor / Reviewed Data
This dataset contains meteorological measurements including temperature, pressure, and relative humidity at multiple heights deployed on tethered balloon system at AWAKEN site G. Z06 refers to the sixth height position of the iMet-XQ2 mounted on the tethered balloon.
17 WIND ENERGY↗
Site G - Atmospheric Sensor / Reviewed Data
This dataset contains meteorological measurements including temperature, pressure, and relative humidity at multiple heights deployed on tethered balloon system at AWAKEN site G. Z05 refers to the fifth height position of the iMet-XQ2 mounted on the tethered balloon.
17 WIND ENERGY↗
Site G - Atmospheric Sensor / Reviewed Data
This dataset contains meteorological measurements including temperature, pressure, and relative humidity at multiple heights deployed on tethered balloon system at AWAKEN site G. Z04 refers to the fourth height position of the iMet-XQ2 mounted on the tethered balloon.
17 WIND ENERGY↗
Site G - Atmospheric Sensor / Reviewed Data
This dataset contains meteorological measurements including temperature, pressure, and relative humidity at multiple heights deployed on tethered balloon system at AWAKEN site G. Z03 refers to the third height position of the iMet-XQ2 mounted on the tethered balloon.
17 WIND ENERGY↗
Site G - Atmospheric Sensor / Reviewed Data
This dataset contains meteorological measurements including temperature, pressure, and relative humidity at multiple heights deployed on tethered balloon system at AWAKEN site G. Z02 refers to the second height position of the iMet-XQ2 mounted on the tethered balloon.
17 WIND ENERGY↗
Site G - Atmospheric Sensor / Reviewed Data
This dataset contains meteorological measurements including temperature, pressure, and relative humidity at multiple heights deployed on tethered balloon system at AWAKEN site G. Z01 refers to the first height position of the iMet-XQ2 mounted on the tethered balloon.
17 WIND ENERGY↗
Site A1 - Atmospheric Sensor / Reviewed Data
This dataset contains meteorological measurements including temperature, pressure, and relative humidity at multiple heights deployed on tethered balloon system at AWAKEN site A1. Z06 refers to the sixth height position of the iMet-XQ2 mounted on the tethered balloon.
17 WIND ENERGY↗