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At least 1,261 records · Page 70

Shuttle structural dynamics characteristics: The analysis and verification

The space shuttle introduced a new dimension in the complexity of the structural dynamics of a space vehicle. The four-body configuration exhibited structural frequencies as low as 2 hertz with a model density on the order of 10 modes per hertz. In the verification process, certain mode shapes and frequencies were identified by the users as more important than others and, as such, the test objectives were oriented toward experimentally extracting those modes and frequencies for analysis and test correlation purposes. To provide the necessary experimental data, a series of ground vibration tests (GVT's) was conducted using test articles ranging from the 1/4-scale structural replica of the space shuttle to the full-scale vehicle. The vibration test and analysis program revealed that the mode shapes and frequency correlations below 10 hertz were good. The quality of correlation of modes between 10 and 20 hertz ranged from good to fair and that of modes above 20 hertz ranged from poor to good. Since the most important modes, based on user preference, were below 10 hertz, it was judged that the shuttle structural dynamic models were adequate for flight certifications.

Modlin, C. T., Jr.↗

Emergence of Long-Range Angular Correlations in Low-Multiplicity Proton-Proton Collisions

This Letter presents the measurement of near-side associated per-trigger yields, denoted ridge yields, from the analysis of angular correlations of charged hadrons in proton-proton collisions at s = 13 TeV . Long-range ridge yields are extracted for pairs of charged particles with a pseudorapidity difference of 1.4 < | Δ η | < 1.8 and a transverse momentum of 1 < p T < 2 GeV / c , as a function of the charged-particle multiplicity measured at midrapidity. This Letter extends the measurements of the ridge yield to the low multiplicity region, where in hadronic collisions it is typically conjectured that a strongly interacting medium is unlikely to be formed. The precision of the new low multiplicity results allows for the first direct quantitative comparison with the results obtained in e + e − collisions at s = 91 GeV and s = 183 – 209 GeV , where initial-state effects such as preequilibrium dynamics and collision geometry are not expected to play a role. In the multiplicity range 8 ≲ ⟨ N ch ⟩ ≲ 24 where the e + e − results have good precision, the measured ridge yields in p p collisions are substantially larger than the limits set in e + e − annihilations. Consequently, the findings presented in this Letter suggest that the processes involved in e + e − annihilations do not contribute significantly to the emergence of long-range correlations in p p collisions. © 2024 CERN, for the ALICE Collaboration 2024 CERN

43 PARTICLE ACCELERATORS↗

Planck intermediate results: XVII. Emission of dust in the diffuse interstellar medium from the far-infrared to microwave frequencies

The dust-Hi correlation is used to characterize the emission properties of dust in the diffuse interstellar medium (ISM) from far infrared wavelengths to microwave frequencies. The field of this encompasses the part of the southern sky best suited to study the cosmic infrared and microwave backgrounds. We cross-correlate sky maps from Planck , the Wilkinson Microwave Anisotropy Probe ( WMAP ), and the diffuse infrared background experiment ( DIRBE ), at 17 frequencies from 23 to 3000 GHz, with the Parkes survey of the 21 cm line emission of neutral atomic hydrogen, over a contiguous area of 7500 deg 2 centred on the southern Galactic pole. We present a general methodology to study the dust-Hi correlation over the sky, including simulations to quantify uncertainties. Our analysis yields four specific results. (1) We map the temperature, submillimetre emissivity, and opacity of the dust per H-atom. The dust temperature is observed to be anti-correlated with the dust emissivity and opacity. We interpret this result as evidence of dust evolution within the diffuse ISM. The mean dust opacity is measured to be (7.1 ± 0.6) × 10 -27 cm 2 H -1 × (v/353 GHz) 1.53 ± 0.03 for 100 ≤ v ≤ 353 GHz. This is a reference value to estimate hydrogen column densities from dust emission at submillimetre and millimetre wavelengths. (2) We map the spectral index β mm of dust emission at millimetre wavelengths (defined here as v ≤ 353 GHz), and find it to be remarkably constant at β mm = 1.51 ± 0.13. We compare it with the far infrared spectral index β FIR derived from greybody fits at higher frequencies, and find a systematic difference, β mm -β FIR = -0.15, which suggests that the dust spectral energy distribution (SED) flattens at v ≤ 353 GHz. (3) We present spectral fits of the microwave emission correlated with Hi from 23 to 353 GHz, which separate dust and anomalous microwave emission (AME). We show that the flattening of the dust SED can be accounted for with an additional component with a blackbody spectrum. This additional component, which accounts for (26 ± 6)% of the dust emission at 100GHz, could represent magnetic dipole emission. Alternatively, it could account for an increasing contribution of carbon dust, or a flattening of the emissivity of amorphous silicates, at millimetre wavelengths. These interpretations make different predictions for the dust polarization SED. (4) We analyse the residuals of the dust-Hi correlation. We identify a Galactic contribution to these residuals, which we model with variations of the dust emissivity on angular scales smaller than that of our correlation analysis. This model of the residuals is used to quantify uncertainties of the CIB power spectrum in a companion Planck paper.

79 ASTRONOMY AND ASTROPHYSICS↗

MSW Variability Mapping and Conversion to Biofuel

MSW (Municipal Solid Waste) is a form of biomass which consists of categorized components of waste/trash. The general categories are paper, yard trash, construction & debris, appliances, tires, glass, metals, aluminum & steel cans, plastics, organics, inorganics, and HHW (Household Hazardous Waste). This project focuses on the factors within a region or population that contribute to variability in the composition of MSW and in turn MSW’s convertibility to biofuel. A list of contributors was determined (Social Vulnerability Index, Access to Public Transportation, Racial Distribution, GDP, Personal Income) and then JMP was used to perform a Multivariate analysis to determine correlations and a Partial Least-Squares regression to determine Variable Importance Plots for each MSW category. In addition to data analysis, the convertibility of MSW to biofuel was studied via microwave pyrolysis system in order to separate and characterize the various gaseous and bio-oil products.

09 BIOMASS FUELS↗

Estimation of uncertainties for subcritical benchmark measurements - 14387

Subcritical measurements are used for many applications including nonproliferation, treaty verification, in-situ monitoring for criticality, and reactor subcriticality monitoring. Most analysis methods involve correlated neutron detection, based upon the property that fission events can create multiple neutrons that are born at nearly the same time (on a scale of 10{sup -13} or 10{sup -14} seconds). Many different time-correlated methods have been used since the 1950's and are still widely utilized today. This particular work describes an uncertainty analysis of measured data using the Hage-Cifarelli formalism of the Feynman Variance-to-Mean method. The Feynman Variance-to-Mean method was introduced by Feynman et al. in 1956 and is based upon the differences between the detector count data and the data that would be expected from measurements taken from a Poissonian source. The Hage-Cifarelli formalism relates moments of the Feynman histograms to several parameters of a system: leakage multiplication (M{sub L}), spontaneous fission rate (F{sub S}), (α,n) neutron emission rate (S{sub α}), detector efficiency (ε), and the moments of the number of neutrons emitted per fission (ν). The first part of the uncertainty method described in this work will show how to determine uncertainties of the first (R{sub 1}) and second (R{sub 2}) reduced factorial moments of the Feynman histograms. The second part of the method will describe how to determine the uncertainties in the other parameters given uncertainties in the reduced factorial moments; in particular, this work will focus on determining the uncertainties in M{sub L} and F{sub S}. This work will utilize measured data from a recent benchmark evaluation with a 4.5 kg sphere of α-phase plutonium to validate the uncertainty analysis. (authors)

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Analysis of remotely sensed data for detecting soil limitations

During 1971 and 1972 a detailed study was conducted on a fallow field in the proposed Oahe Irrigation Project to determine the relationship between the tonal variation observed on aerial photographs and the properties of eroded soil. Correlation and regression analysis of digitized, multiemulsion, color infrared film (2443) data and detailed field data revealed a highly significant correlation between film transmittance and several soil properties indicative of the erosion limitation. Computer classification of the multiemulsion film data resulted in maps portraying the eroded soil and the normal soil. Both correlation and computer classification results were best using the reflectance data from the red spectral band. The results showed film transmittance was actually measuring the reflectivity of the soil surface which was increased by the incorporation of the light colored, calcareous parent material exposed by erosion or tillage on soils with thin surface horizons.

Benson, L. A.↗

sMicroRNA-28-5p acts as a metastasis suppressor in gastric cancer by targeting Nrf2

The transcription factor nuclear factor (erythroid-2)-related factor 2 (Nrf2) can principally serve a mode of protection for both the normal cells and cancer cells from cellular stress, and elevates cancer cell survival. microRNA-28 (miR-28) has been involved in the regulation of Nrf2 expression in breast epithelial cells. However, no comprehensive analysis has been conducted regarding the function of miR-28-5p regulating Nrf2 in gastric cancer (GC). In this study, we aimed to evaluate their interaction and biological roles in the migration and invasion of GC cells. The expression of Nrf2 in the cancer tissues harvested from 42 patients with GC was examined by an array of molecular techniques comprising of Immunohistochemical staining, RT-qPCR and Western blot analysis. Kaplan-Meier method was adopted for analysis of the correlation of Nrf2 with the prognosis of GC patients. Interaction between miR-28-5p and Nrf2 was determined using the bioinformatics analysis and dual luciferase reporter gene assay. Gain- and loss-of-function studies of miR-28-5p and Nrf2 were conducted to elucidate their effects on GC cell migration, invasion and metastasis, as well as expression pattern of several epithelial-mesenchymal transition (EMT)-related proteins. Results indicated that the expression pattern of Nrf2 was significantly upregulated in GC tissues and indicative of poor prognosis of GC patients. miR-28-5p was verified to target Nrf2 and downregulate its expression. GC cells with overexpression of miR-28-5p or Nrf2 knockdown exhibited a marked reduction in the migrated and invasive abilities, along with the N-cadherin expression yet an increase of E-cadherin expression. Furthermore, miR-28-5p exerted an inhibitory function on the metastatic and tumorigenicity of GC cells. In conclusion, miR-28-5p is a comprehensive tumor suppressor that inhibits GC cell migration and invasion through repressing the Nrf2 expression. Therefore, miR-28-5p may serve as a potential biomarker for the prognosis of GC and a novel therapeutic target in advanced GC.

60 APPLIED LIFE SCIENCES↗

Study of photon correlation techniques for processing of laser velocimeter signals

The objective was to provide the theory and a system design for a new type of photon counting processor for low level dual scatter laser velocimeter (LV) signals which would be capable of both the first order measurements of mean flow and turbulence intensity and also the second order time statistics: cross correlation auto correlation, and related spectra. A general Poisson process model for low level LV signals and noise which is valid from the photon-resolved regime all the way to the limiting case of nonstationary Gaussian noise was used. Computer simulation algorithms and higher order statistical moment analysis of Poisson processes were derived and applied to the analysis of photon correlation techniques. A system design using a unique dual correlate and subtract frequency discriminator technique is postulated and analyzed. Expectation analysis indicates that the objective measurements are feasible.

Mayo, W. T., Jr.↗

Fuselage Versus Subcomponent Panel Response Correlation Based on ABAQUS Explicit Progressive Damage Analysis Tools

Analysis performed in this study substantiates the need for high fidelity vehicle level progressive damage analyses (PDA) structural models for use in the verification and validation of proposed sub-scale structural models and to support required full-scale vehicle level testing. PDA results are presented that capture and correlate the responses of sub-scale 3-stringer and 7-stringer panel models and an idealized 8-ft diameter fuselage model, which provides a vehicle level environment for the 7-stringer sub-scale panel model. Two unique skin-stringer attachment assumptions are considered and correlated in the models analyzed: the TIE constraint interface versus the cohesive element (COH3D8) interface. Evaluating different interfaces allows for assessing a range of predicted damage modes, including delamination and crack propagation responses. Damage models considered in this study are the ABAQUS built-in Hashin procedure and the COmplete STress Reduction (COSTR) damage procedure implemented through a VUMAT user subroutine using the ABAQUS/Explicit code.

Gould, Kevin E.↗

The Sealing Mechanisms of a Fracture in Opalinus Clay as Revealed by in situ Synchrotron X-Ray Micro-Tomography

The detailed mechanisms of the sealing of a single fracture, from hydration to almost complete closure by increase of confining pressure, as monitored from in situ synchrotron X-ray microtomography during the flow of carbonated water, is here shown for the first time. Different mechanisms play the key role at different stages in the evolution of the fracture. Hydration mechanically weakens the surfaces of the fracture and induces a first closure due to microcracking at the asperity contacts, increasing their size and creating choke points. Increase in confining stress promptly hydraulically seals the fracture by closing the main choke point, with a relative small deformation of the sample. Finally, the more pervasive mechanical deformation observed at higher stresses almost completely seals the whole fracture. The evolution of the sample has been described and quantified using 4D image processing, focusing on the evolution of aperture and digital volume correlation. Hydraulic properties of the sample at different stages have been modeled via Stokes flow simulation, and the results compared to the morphometric analysis, finding positive correlations with the average fracture aperture variation along the flowpath in function of confining pressure. Opalinus Clay is found to be a rock markedly prone to sealing in case of flow with carbonated water; this behavior is the result of the large fraction of clays and of its microstructure, lacking both cementing phases and large stiff particles. CO2 in this sample has no evident role in the evolution of the fracture; chemically induced weathering on the surface has not been detected, in contrast with the behavior observed in samples with carbonates as cementing phase.

58 GEOSCIENCES↗

Correlation between EVs and Other Loads in Probabilistic Load Flow for Distribution Systems

To date, most probabilistic studies have assumed independence between the various loads and other inputs on the distribution system. It is well know however, that this is typically not the case. The work presented in the paper expands upon a previous unbalanced three-phase probabilistic load flow study on a residential feeder with a 50 % penetration of electric vehicles, under three different charging schemes where different correlation scenarios between the load flow inputs are considered. The data for the probabilistic load flow study are derived from a voltage dependent time-variant deterministic load flow. Here the deterministic load flow data are examined further to gain a better understanding of the correlation between the customer and electric vehicle charging loads, and how different charging schemes may impact it further. Four different correlation scenarios are then created and details on how the probabilistic load flow inputs are created is also presented; demonstrating the need for better analysis on the correlation between system inputs. This paper hopes to open the discussion and start the push for future research into understanding the correlation and effects of various system inputs on the probabilistic nature of distribution systems, and how to apply this knowledge to future studies.

Melhorn, Alexander C.↗

The relationship of storm severity to directionally resolved radio emissions

The objective was to provide continuous observation of atmospheric electrical activity occurring in association with tropical storms in the Gulf of Mexico. The observations were to include the location of all detected intracloud and cloud-to-ground lightning activity occurring in the storm. To provide synoptic scale coverage, a phase linear interferometer high frequency direction finder (HFDF) system was constructed and developed at Marshall Space Flight Center (MSFC). This was used in concert with the existing HFDF interferometer at the southwest research institute to provide lightning location data through triangulation. Atmospheric electrical events were synchronized through the use of satellite receivers at each site. The intent of the data analysis was to correlate the location of electrical centers of activity with radar and satellite imagry to identify areas of intense convection within the tropical storm system. Analysis of the hurricane Alicia data indicate a center of atmospheric electrical activity associated with the vortex of the storm. The center appears to rotate from the Northern side of the vortex to the Southern side during the period of observation. An analysis of the atmospheric electrical burst rates associated with hurrican Alicia indicates that the electrical activity appears to maximize at the time of greatest storm intensity, i.e., maximum winds and lowest central pressure.

Johnson, R. L.↗

Design, Analysis and Fabrication of Secondary Structural Components for the Habitat Demonstration Unit-Deep Space Habitat

In support of NASA s Habitat Demonstration Unit - Deep Space Habitat Prototype, a number of evolved structural sections were designed, fabricated, analyzed and installed in the 5 meter diameter prototype. The hardware consisted of three principal structural sections, and included the development of novel fastener insert concepts. The articles developed consisted of: 1) 1/8th of the primary flooring section, 2) an inner radius floor beam support which interfaced with, and supported (1), 3) two upper hatch section prototypes, and 4) novel insert designs for mechanical fastener attachments. Advanced manufacturing approaches were utilized in the fabrication of the components. The structural components were developed using current commercial aircraft constructions as a baseline (for both the flooring components and their associated mechanical fastener inserts). The structural sections utilized honeycomb sandwich panels. The core section consisted of 1/8th inch cell size Nomex, at 9 lbs/cu ft, and which was 0.66 inches thick. The facesheets had 3 plys each, with a thickness of 0.010 inches per ply, made from woven E-glass with epoxy reinforcement. Analysis activities consisted of both analytical models, as well as initial closed form calculations. Testing was conducted to help verify analysis model inputs, as well as to facilitate correlation between testing and analysis. Test activities consisted of both 4 point bending tests as well as compressive core crush sequences. This paper presents an overview of this activity, and discusses issues encountered during the various phases of the applied research effort, and its relevance to future space based habitats.

Smith, Russell W.↗

Revisit of Energy Use and Technologies of High Performance Buildings

Energy consumed by buildings accounts for one third of the world?s total primary energy use. Associated with the conscious of energy savings in buildings, High Performance Buildings (HPBs) has surged across the world, with wide promotion and adoption of various performance rating and certification systems. It is valuable to look into the actual energy performance of HPBs and to understand their influencing factors. To shed some light on this topic, this paper conducted a series of portfolio analysis based on a database of 51 high performance office buildings across the world. Analyses showed that the actual site Energy Use Intensity (EUI) of the 51 buildings varied by a factor of up to 11, indicating a large scale of variation of the actual energy performance of the current HPBs. Further analysis of the correlation between EUI and climate elucidated ubiquitous phenomenon of EUI scatter throughout all climate zones, implying that the weather is not a decisive factor, although important, for the actual energy consumption of an individual building. On the building size via EUI, analysis disclosed that smaller buildings have a tendency to achieving lower energy use. Even so, the correlation is not absolute since some large buildings demonstrated low energy use while some small buildings performed opposite. Concerning the technologies, statistics indicated that the application of some technologies had correlations with some specific building size and climate characteristic. However, it was still hard to pinpoint a set of technologies which was directly correlative with a group of low EUI buildings. It is concluded that no a single factor essentially determines the actual energy performance of HPBs. To deliver energy-efficient buildings, an integrated design taking account of climate, technology, occupant behavior as well as operation and maintenance should be implemented.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

SU-E-T-142: Automatic Linac Log File: Analysis and Reporting

Purpose: End to end QA for IMRT/VMAT is time consuming. Automated linac log file analysis and recalculation of daily recorded fluence, and hence dose, distribution bring this closer. Methods: Matlab (R2014b, Mathworks) software was written to read in and analyse IMRT/VMAT trajectory log files (TrueBeam 1.5, Varian Medical Systems) overnight, and are archived on a backed-up network drive (figure). A summary report (PDF) is sent by email to the duty linac physicist. A structured summary report (PDF) for each patient is automatically updated for embedding into the R&V system (Mosaiq 2.5, Elekta AG). The report contains cross-referenced hyperlinks to ease navigation between treatment fractions. Gamma analysis can be performed on planned (DICOM RTPlan) and treated (trajectory log) fluence distributions. Trajectory log files can be converted into RTPlan files for dose distribution calculation (Eclipse, AAA10.0.28, VMS). Results: All leaf positions are within +/−0.10mm: 57% within +/−0.01mm; 89% within 0.05mm. Mean leaf position deviation is 0.02mm. Gantry angle variations lie in the range −0.1 to 0.3 degrees, mean 0.04 degrees. Fluence verification shows excellent agreement between planned and treated fluence. Agreement between planned and treated dose distribution, the derived from log files, is very good. Conclusion: Automated log file analysis is a valuable tool for the busy physicist, enabling potential treated fluence distribution errors to be quickly identified. In the near future we will correlate trajectory log analysis with routine IMRT/VMAT QA analysis. This has the potential to reduce, but not eliminate, the QA workload.

60 APPLIED LIFE SCIENCES↗

Evaluation of structural integrity using integrated testing and analysis

An integrated approach to dynamic testing and mathematical model analysis is described. The overall approach addresses four key tasks, namely, pretest planning and analysis, test data acquisition, data reduction and analysis, and test/analysis correlation and mathematical model updates. Several key software programs are employed to accomplish this task. They are a leading finite element code, a sophisticated data analysis processor and a graphical pre- and post-processor along with an advanced interface utility. Several practical structures are used to illustrate tools and concepts employed in the integrated test analysis process.

Coppolino, Robert N.↗

Revealing the surface interface correlations in a-Si:H films by 2D detrended fluctuation analysis

Modified 2D detrended fluctuation analysis is used to reveal surface interface correlations. Model surfaces with a known rule of construction and different structural properties (ordered, weakly ordered, and random) are investigated. Obtained values of the scaling exponent are compared with known scales of values. Features of the scaling behavior on different scales are established. It is shown that the method can be effectively applied to studying the surface evolution, e.g., in growing disordered semiconductor films, estimating the degree of ordering, and investigating self-organization processes. The surfaces of amorphous hydrogenated silicon films are investigated by atomic force microscopy. 2D detrended fluctuation analysis shows the non-monofractality of the surfaces and the presence of several surface interface components: noise and sinusoidal.

36 MATERIALS SCIENCE↗

MiR-153 inhibits migration and invasion of human non-small-cell lung cancer by targeting ADAM19

Highlights: • Decreased miR-153 and up-regulated ADAM19 are correlated with NSCLC pathology. • MiR-153 inhibits the proliferation and migration and invasion of NSCLC cells in vitro. • ADAM19 is a direct target of miR-153. • ADAM19 is involved in miR-153-suppressed migration and invasion of NSCLC cells. - Abstract: MiR-153 was reported to be dysregulated in some human cancers. However, the function and mechanism of miR-153 in lung cancer cells remains unknown. In this study, we investigated the role of miR-153 in human non-small-cell lung cancer (NSCLC). Using qRT-PCR, we demonstrated that miR-153 was significantly decreased in clinical NSCLC tissues and cell lines, and downregulation of miR-153 was significantly correlated with lymph node status. We further found that ectopic expression of miR-153 significantly inhibited the proliferation and migration and invasion of NSCLC cells in vitro, suggesting that miR-153 may be a novel tumor suppressor in NSCLC. Further integrated analysis revealed that ADAM19 is as a direct and functional target of miR-153. Luciferase reporter assay demonstrated that miR-153 directly targeted 3′UTR of ADAM19, and correlation analysis revealed an inverse correlation between miR-153 and ADAM19 mRNA levels in clinical NSCLC tissues. Knockdown of ADAM19 inhibited migration and invasion of NSCLC cells which was similar with effects of overexpression of miR-153, while overexpression of ADAM19 attenuated the function of miR-153 in NSCLC cells. Taken together, our results highlight the significance of miR-153 and ADAM19 in the development and progression of NSCLC.

60 APPLIED LIFE SCIENCES↗