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At least 1,387 records · Page 77

An Imaging Surface Plasmon Resonance Biosensor Assay for the Detection of T-2 Toxin and Masked T-2 Toxin-3-Glucoside in Wheat

A sensitive, rapid, and reproducible imaging surface plasmon resonance (iSPR) biosensor assay was developed to detect T-2 toxin and T-2 toxin-3-glucoside (T2-G) in wheat. In this competitive assay, an amplification strategy was used after conjugating a secondary antibody (Ab 2 ) with gold nanoparticles. Wheat samples were extracted with a methanol/water mixture (80:20 v/v), then diluted with an equal volume of primary antibody (Ab1) for analysis. Matrix-matched calibration curves were prepared to determine T-2 toxin and T2-G. Recovery studies were conducted at three spiking levels in blank wheat. Mean recoveries ranged from 86 to 90%, with relative standard deviations for repeatability (RSDr) of less than 6%. Limits of detection were 1.2 ng/mL of T-2 toxin and 0.9 ng/mL of T2-G, equivalent to their levels in wheat, of 48 and 36 µg/kg, respectively. The developed iSPR assay was rapid and provided enough sensitivity for the monitoring of T-2 toxin/T2-G in wheat. This is the first iSPR assay useful for detecting the “masked” T2-G in wheat.

Food Science & Technology↗

Persistent Viral Reservoirs in Lymphoid Tissues in SIV-Infected Rhesus Macaques of Chinese-Origin on Suppressive Antiretroviral Therapy

Understanding HIV latent reservoirs in tissues is essential for the development of new strategies targeting these sites for eradication. Here, we assessed the size of latent reservoirs and the source of residual viruses in multiple lymphoid tissues of SIV-infected and fully suppressed rhesus macaques of Chinese-origin (cRMs). Eight cRMs were infected with SIVmac251 and treated with tenofovir and emtricitabine daily for 24 weeks initiated 4 weeks post-infection. Four of the eight animals reached sustained full viral suppression with undetectable viremia. The levels of cell-associated SIV DNA varied in peripheral blood mononuclear cells (PBMCs) and multiple lymphoid tissues, but with higher levels in the mesenteric lymph nodes (MesLNs). The levels of cell-associated SIV RNA also varied in different tissues. The higher frequency of viral RNA detection in the MesLNs was also observed by in situ hybridization. Consistently, the infection unit per million cells (IUPM) in the MesLNs was higher than in PBMCs and other tested lymphoid tissues by quantitative viral outgrowth assay (QVOA). Furthermore, env gp120 from tissue SIV RNA was amplified by single genome amplification. Phylogenetic analysis revealed diverse variants from tissues parallel to the viral inoculum in all viral suppressed animals. These results demonstrate that the latency and viral reservoirs in the lymphoid tissues still exist in aviremic macaques under full suppressive therapy. Moreover, the size of viral latent reservoirs differs in various lymphoid tissues with a relatively larger size in the MesLNs.

60 APPLIED LIFE SCIENCES↗

Identifying Interaction Location in SuperCDMS Detectors

The Super Cryogenic Dark Matter Search (SuperCDMS) experiment uses silicon and germanium particle detectors operated at temperatures of ∼ 30 mK to search for Weakly Interacting Massive Particles (WIMPs), which are candidate dark matter particles that interact weakly with nuclei in the detectors. In operating these detectors, it is required not only to measure the energy of the interaction between the WIMP and the nuclei, but also to reconstruct where the interaction occurred, as the location can be used to separate background interactions from signal and to correct for variations with the location of the energy response. In this project, we, as a team from the University of Minnesota, aim to address the problem of accurately reconstructing the locations of interactions in the SuperCDMS detectors using machine learning methods. The dataset we provided here includes interactions at thirteen different locations from test data taken at the University of Minnesota. For each interaction, a set of parameters was extracted from the signals from each of the five sensors. These parameters represent information known to be sensitive to interaction location, including the relative timing between pulses in different channels, and features like the pulse shape. The relative amplitudes of the pulses are also relevant but due to instabilities in amplification during the test, this data is not included. The parameters included for each interaction are described in our project document. For more details, feel free to check our Github page: https://fair-umn.github.io/FAIR-UMN-CDMS/

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

The Hawaii SCUBA-2 Lensing Cluster Survey: Radio-detected Submillimeter Galaxies in the HST Frontier Fields

In this second paper of the Hawaii SCUBA-2 Lensing Cluster Survey series, we cross-match SCUBA-2 maps with 3 and 6 GHz images from the Janksy-VLA Frontier Fields Legacy Survey for three cluster fields, MACS J0416.1–2403, MACS J0717.5+3745, and MACS J1149.5+2223. Within the HST coverage, 14 out of 44 850 μm sources have 3 GHz counterparts, five of which are also detected at 6 GHz. The 850 μm flux densities of these detected sources span from 0.7 to 4.4 mJy after correcting for lensing amplification. The median redshift of the sample is z=1.28{sub −0.09}{sup +0.07}, much lower than the typical redshifts (z = 2–3) of brighter submillimeter galaxies (SMGs) in the literature. In addition, we find that our sources have lower dust temperatures than those of the brighter SMGs. This is also confirmed by an analysis of the ratio between infrared star-formation rate and 850 μm flux density. However, these 14 sources may not represent the general submillimeter population at the same flux range, given that the SCUBA-2 sources without radio counterparts are likely at higher redshifts. Detection of these sources would require deeper radio images or submillimeter interferometry.

79 ASTRONOMY AND ASTROPHYSICS↗

Fossil Shell in 3C 84 as TeV γ-Ray Emitter and Cosmic-Ray Accelerator

We explore physical properties of the shocked external medium (i.e., a shell) in 3C 84 associated with the recurrent radio lobe born around 1960. In the previous work of Ito et al., we investigated a dynamical and radiative evolution of such a shell after the central engine stops the jet launching, and we found that a fossil-shell emission overwhelms that of the rapidly fading radio lobe. We apply this model to 3C 84 and find the following. (1) The fossil shell made of shocked diffuse ambient matter with the number density of 0.3 cm{sup −3} radiates bright inverse-Compton (IC) emission with the seed photons of the radio emission from the central compact region and the IC emission is above the sensitivity threshold of the Cherenkov Telescope Array (CTA). (2) When the fossil shell is produced in a geometrically thick ionized plasma with the number density of 10{sup 3} cm{sup −3}, the field strength in the shell may reach about 17 mG in the presence of magnetic fields amplification and the radio emission becomes comparable to the sensitivity of deep imaging VLBI observations. The possible production of ultra high-energy cosmic-rays (UHECRs) in the dense shocked plasma is also argued.

79 ASTRONOMY AND ASTROPHYSICS↗

Discovery of Molecular and Atomic Clouds Associated with the Magellanic Superbubble 30 Doradus C

We analyzed the 2.6 mm CO and 21 cm H i lines toward the Magellanic superbubble 30 Doradus C, in order to reveal the associated molecular and atomic gas. We uncovered five molecular clouds in a velocity range from 251 to 276 km s{sup −1} toward the western shell. The non-thermal X-rays are clearly enhanced around the molecular clouds on a parsec scale, suggesting possible evidence for magnetic field amplification via shock–cloud interaction. The thermal X-rays are brighter in the eastern shell, where there are no dense molecular or atomic clouds, opposite to the western shell. The TeV γ-ray distribution may spatially match the total interstellar proton column density as well as the non-thermal X-rays. If the hadronic γ-ray is dominant, the total energy of the cosmic-ray protons is at least ∼1.2×10{sup 50} erg with the estimated mean interstellar proton density ∼60 cm{sup −3}. In addition, the γ-ray flux associated with the molecular cloud (e.g., MC3) could be detected and resolved by the Cherenkov Telescope Array (CTA). This should permit CTA to probe the diffusion of cosmic-rays into the associated dense ISM.

79 ASTRONOMY AND ASTROPHYSICS↗

Magnifying the Early Episodes of Star Formation: Super Star Clusters at Cosmological Distances

We study the spectrophotometric properties of a highly magnified (μ≃40--70) pair of stellar systems identified at z = 3.2222 behind the Hubble Frontier Field galaxy cluster MACS J0416. Five multiple images (out of six) have been spectroscopically confirmed by means of VLT/MUSE and VLT/X-Shooter observations. Each image includes two faint (m{sub UV}≃30.6), young (≲100 Myr), low-mass (<10{sup 7} M{sub ⊙}), low-metallicity (12 + Log(O/H) ≃ 7.7, or 1/10 solar), and compact (30 pc effective radius) stellar systems separated by ≃300 pc after correcting for lensing amplification. We measured several rest-frame ultraviolet and optical narrow (σ{sub v}≲25 km s{sup −1}) high-ionization lines. These features may be the signature of very hot (T>50,000 K) stars within dense stellar clusters, whose dynamical mass is likely dominated by the stellar component. Remarkably, the ultraviolet metal lines are not accompanied by Lyα emission (e.g., C iv/Lyα > 15), despite the fact that the Lyα line flux is expected to be 150 times brighter (inferred from the Hβ flux). A spatially offset, strongly magnified (μ>50) Lyα emission with a spatial extent ≲7.6 kpc{sup 2} is instead identified 2 kpc away from the system. The origin of such a faint emission could be the result of fluorescent Lyα induced by a transverse leakage of ionizing radiation emerging from the stellar systems and/or may be associated with an underlying and barely detected object (with m{sub UV}>34 de-lensed). This is the first confirmed metal-line emitter at such low-luminosity and redshift without Lyα emission—suggesting that, at least in some cases, a non-uniform covering factor of the neutral gas might hamper the Lyα detection.

79 ASTRONOMY AND ASTROPHYSICS↗

Magnetized High Velocity Clouds in the Galactic Halo: A New Distance Constraint

High velocity gas that does not conform to Galactic rotation is observed throughout the Galaxy’s halo. One component of this gas, H i high velocity clouds (HVCs), have attracted attention since their discovery in the 1960s and remain controversial in terms of their origins, largely due to the lack of reliable distance estimates. The recent discovery of enhanced magnetic fields toward HVCs has encouraged us to explore their connection to cloud evolution, kinematics, and survival as they fall through the magnetized Galactic halo. For a reasonable model of the halo magnetic field, most infalling clouds see transverse rather than radial field lines. We find that significant compression (and thereby amplification) of the ambient magnetic field occurs in front of the cloud and in the tail of material stripped from the cloud. The compressed transverse field attenuates hydrodynamical instabilities. This delays cloud destruction, though not indefinitely. The observed B field compression is related to the cloud’s distance from the Galactic plane. As a result, the observed rotation measure provides useful distance information on a cloud’s location.

79 ASTRONOMY AND ASTROPHYSICS↗

Electron Heating in Low Mach Number Perpendicular Shocks. II. Dependence on the Pre-shock Conditions

Recent X-ray observations of merger shocks in galaxy clusters have shown that the post-shock plasma is two-temperature, with the protons being hotter than the electrons. Here, the second of a series, we investigate the efficiency of irreversible electron heating in perpendicular low Mach number shocks, by means of two-dimensional particle-in-cell simulations. We consider values of plasma beta (the ratio of thermal and magnetic pressures) in the range 4 ≲ β p0 ≲ 32, and sonic Mach number (the ratio of shock speed to pre-shock sound speed) in the range 2 ≲ M s ≲ 5, as appropriate for galaxy cluster shocks. As reflected in Paper I, magnetic field amplification—induced by shock compression of the pre-shock field, or by strong proton cyclotron and mirror modes accompanying the relaxation of proton temperature anisotropy—can drive the electron temperature anisotropy beyond the threshold of the electron whistler instability. The growth of whistler waves breaks the electron adiabatic invariance, and allows for efficient entropy production. We determine that the post-shock electron temperature T e2 exceeds the adiabatic expectation ${T}_{e2,\mathrm{ad}}$ by an amount $({T}_{e2}-{T}_{e2,\mathrm{ad}})/{T}_{e0}\simeq 0.044\,{M}_{s}({M}_{s}-1)$ (here, T e0 is the pre-shock temperature), which depends only weakly on the plasma beta over the range 4 lesssim β p0 lesssim 32 that we have explored, as well as on the proton-to-electron mass ratio (the coefficient of sime0.044 is measured for our fiducial ${m}_{i}/{m}_{e}=49$, and we estimate that it will decrease to sime0.03 for the realistic mass ratio). Our results have important implications for current and future observations of galaxy cluster shocks in the radio band (synchrotron emission and Sunyaev–Zel'dovich effect) and at X-ray frequencies.

79 ASTRONOMY AND ASTROPHYSICS↗

The Discovery of a Gravitationally Lensed Supernova Ia at Redshift 2.22

Here, we present the discovery and measurements of a gravitationally lensed supernova (SN) behind the galaxy cluster MOO J1014+0038. Based on multi-band Hubble Space Telescope and Very Large Telescope (VLT) photometry of the supernova, and VLT spectroscopy of the host galaxy, we find a 97.5% probability that this SN is a SN Ia, and a 2.5% chance of a CC SN. Our typing algorithm combines the shape and color of the light curve with the expected rates of each SN type in the host galaxy. With a redshift of 2.2216, this is the highest redshift SN Ia discovered with a spectroscopic host-galaxy redshift. A further distinguishing feature is that the lensing cluster, at redshift 1.23, is the most distant to date to have an amplified SN. The SN lies in the middle of the color and light-curve shape distributions found at lower redshift, disfavoring strong evolution to z = 2.22. We estimate an amplification due to gravitational lensing of 2.8 +0.6 -0.5 (1.10 ± 0.23 mag)---compatible with the value estimated from the weak-lensing-derived mass and the mass-concentration relation from LambdaCDM simulations---making it the most amplified SN Ia discovered behind a galaxy cluster.

79 ASTRONOMY AND ASTROPHYSICS↗

On the Background-gyroresonant Character of Bell’s Instability in the Large-current Regime

We demonstrate that the Bell instability, which is widely considered potentially significant for cosmic-ray (CR) acceleration, is the low-frequency limit of a gyroresonant interaction between the protons of the interstellar medium and shear-Alfvén waves. At large CR current densities, its growth rate is therefore limited by the proton gyrofrequency, and two modes emerge from the cold-beam dispersion relation. A third mode driven by electron gyroresonance is only weakly unstable at low current densities. We report on implications for magnetic field amplification and its saturation in the vicinity of supernova remnants.

79 ASTRONOMY AND ASTROPHYSICS↗

Solar Wind Turbulence from 1 to 45 au. III. Anisotropy of Magnetic Fluctuations in the Inertial Range Using Voyager and ACE Observations

We examine both Voyager and Advanced Composition Explorer magnetic field measurements at frequencies that characterize the inertial range and evaluate the anisotropy of the fluctuations as they relate to both the compressive component and underlying wavevector anisotropy of the turbulence. The magnetic fluctuation anisotropy as it relates to the compressive component is directly dependent upon both the plasma beta of the thermal proton component and the ratio of magnetic fluctuation magnitude to the strength of the mean magnetic field. This has been seen before at 1 au. The magnetic fluctuation anisotropy in the plane perpendicular to the mean magnetic field, which is a measure of the anisotropy of the underlying wavevector distribution, should depend on the angle between the mean magnetic field and the radial direction and should be confined to values between one and the index of the power spectrum, which is typically 5/3. Our results show that the average of this anisotropy exceeds the value of the spectral index and is out of bounds with the theory. Although the results are suggestive of past analyses, we find that spherical expansion of the turbulence may offer at least a partial explanation of the apparent amplification of this measured anisotropy.

heliosphere↗

Numerical Simulation of Electron Magnetohydrodynamics with Landau-quantized Electrons in Magnetar Crusts

Abstract In magnetar crusts, magnetic fields are sufficiently strong to confine electrons into a small to moderate number of quantized Landau levels. This can have a dramatic effect on the crust's thermodynamic properties, generating field-dependent de Haas–van Alphen oscillations. We previously argued that the large-amplitude oscillations of the magnetic susceptibility could enhance the ohmic dissipation of the magnetic field by continuously generating small-scale, rapidly dissipating field features. This could be important to magnetar field evolution and contribute to their observed higher temperatures. To study this, we performed quasi-3D numerical simulations of electron MHD in a representative volume of neutron star crust matter, for the first time including the magnetization and magnetic susceptibility resulting from Landau quantization. We find that the potential enhancement in the ohmic dissipation rate due to this effect can be a factor ∼3 for temperatures of the order of 10 8 K, and ∼4.5 for temperatures of the order of 5 × 10 7 K, depending on the magnetic field configuration. The nonlinear Hall term is crucial to this amplification: without it, the magnetic field decay is only enhanced by a factor ≲2 even at 5 × 10 7 K. These effects generate a high wavenumber plateau in the magnetic energy spectrum associated with the small-scale de Haas–van Alphen oscillations. Our results suggest that this mechanism could help explain the magnetar heating problem, though due to the effect's temperature-dependence, full magneto-thermal evolution simulations in a realistic stellar model are needed to judge whether it is viable explanation.

Rau, Peter B. (ORCID:0000000152209277)↗

The Role of Three-dimensional Effects on Ion Injection and Acceleration in Perpendicular Shocks

Understanding the conditions that enable particle acceleration at nonrelativistic collisionless shocks is essential to unveil the origin of cosmic rays. We employ 2D and 3D hybrid simulations (with kinetic ions and fluid electrons) to explore particle acceleration and magnetic field amplification in nonrelativistic perpendicular shocks, focusing on the role of shock drift acceleration and its dependence on the shock Mach number. We perform an analysis of the ion injection process and demonstrate why efficient acceleration is only observed in 3D. In particular, we show that ion injection critically depends on the “porosity” of the magnetic turbulence in the downstream region near the shock, a property describing how easily the postshock region allows particles to traverse it and return upstream without being trapped. This effect can only be properly captured in 3D. Additionally, we explore the impact of numerical resolution on ion energization, highlighting how resolving small-scale turbulence—on scales below the thermal ion gyroradius—is essential for accurately modeling particle injection. Overall, our results emphasize the necessity of high-resolution 3D simulations to capture the fundamental microphysics driving particle acceleration at perpendicular shocks.

Orusa, Luca [Princeton Univ., NJ (United States); ↗

Long-term Variability of H{sub 2}CO Masers in Star-forming Regions

We present results of a multi-epoch monitoring program on variability of 6 cm formaldehyde (H{sub 2}CO) masers in the massive star-forming region NGC 7538 IRS 1 from 2008 to 2015, conducted with the Green Bank Telescope, the Westerbork Radio Telescope , and the Very Large Array. We found that the similar variability behaviors of the two formaldehyde maser velocity components in NGC 7538 IRS 1 (which was pointed out by Araya and collaborators in 2007) have continued. The possibility that the variability is caused by changes in the maser amplification path in regions with similar morphology and kinematics is discussed. We also observed 12.2 GHz methanol and 22.2 GHz water masers toward NGC 7538 IRS 1. The brightest maser components of CH{sub 3}OH and H{sub 2}O species show a decrease in flux density as a function of time. The brightest H{sub 2}CO maser component also shows a decrease in flux density and has a similar LSR velocity to the brightest H{sub 2}O and 12.2 GHz CH{sub 3}OH masers. The line parameters of radio recombination lines and the 20.17 and 20.97 GHz CH{sub 3}OH transitions in NGC 7538 IRS 1 are also reported. In addition, we observed five other 6 cm formaldehyde maser regions. We found no evidence of significant variability of the 6 cm masers in these regions with respect to previous observations, the only possible exception being the maser in G29.96−0.02. All six sources were also observed in the H{sub 2}{sup 13}CO isotopologue transition of the 6 cm H{sub 2}CO line; H{sub 2}{sup 13}CO absorption was detected in five of the sources. Estimated column density ratios [H{sub 2}{sup 12}CO]/[H{sub 2}{sup 13}CO] are reported.

79 ASTRONOMY AND ASTROPHYSICS↗

$\mathrm{SageNet}$: Fast Neural Network Emulation of the Stiff-amplified Gravitational Waves from Inflation

Accurate modeling of the inflationary gravitational waves (GWs) requires time-consuming, iterative numerical integrations of differential equations to take into account their backreaction on the expansion history. To improve computational efficiency while preserving accuracy, we present the Stiff-amplified Gravitational-wave Emulator Network (SageNet), a deep learning framework designed to replace conventional numerical solvers (code available at https://github.com/YifangLuo/SageNet). SageNet employs a long short-term memory architecture to emulate the present-day energy density spectrum of the inflationary GWs with possible stiff amplification, Ω GW (f). Trained on a data set of 25,689 numerically generated solutions, SageNet allows accurate reconstructions of Ω GW (f) and generalizes well to a wide range of cosmological parameters; 90.9% of the test emulations with randomly distributed parameters exhibit errors of under 4%. In addition, SageNet demonstrates its ability to learn and reproduce the artificial, adaptive sampling patterns in numerical calculations, which implement denser sampling of frequencies around changes in spectral indices in Ω GW (f). The dual capability of learning both physical and artificial features of the numerical GW spectra establishes SageNet as a robust alternative to exact numerical methods. Finally, our benchmark tests show that SageNet reduces the computation time from tens of seconds to milliseconds, achieving a speedup of ∼10 4 times over standard CPU-based numerical solvers with the potential for further acceleration on GPU hardware. These capabilities make SageNet a powerful tool for accelerating Bayesian inference procedures for extended cosmological models. In a broad sense, the SageNet framework offers a fast, accurate, and generalizable solution to modeling cosmological observables whose theoretical predictions demand costly differential equation solvers.

Astronomy data modeling↗

Discovery of a Lensed Ultrabright Submillimeter Galaxy at z = 2.0439

We report an ultrabright lensed submillimeter galaxy (SMG) at z = 2.0439, WISE J132934.18+224327.3, identified as a result of a full-sky cross-correlation of the AllWISE and Planck compact source catalogs aimed to search for bright analogs of the SMG SMM J2135, the Cosmic Eyelash. Inspection of archival SCUBA-2 observations of the candidates revealed a source with fluxes (S{sub 850μm}=130 mJy) consistent with the Planck measurements. The centroid of the SCUBA-2 source coincides within 1 arcsec with the position of the AllWISE mid-IR source, and, remarkably, with an arc-shaped lensed galaxy in HST images at visible wavelengths. Low-resolution rest-frame UV-optical spectroscopy of this lensed galaxy obtained with 10.4 m GTC reveals the typical absorption lines of a starburst galaxy. Gemini-N near-IR spectroscopy provided a clear detection of H{sub α} emission. The lensed source appears to be gravitationally magnified by a massive foreground galaxy cluster lens at z = 0.44; modeling with Lenstool indicates a lensing amplification factor of 11 ± 2. We determine an intrinsic rest-frame 8–1000 μm luminosity, L{sub IR}, of (1.3±0.1)×10{sup 13} L{sub ⊙}, and a likely star formation rate (SFR) of ∼500--2000 M{sub ⊙} yr{sup −1}. The SED shows a remarkable similarity with the Cosmic Eyelash from optical-mid/IR to submillimeter/radio, albeit at higher fluxes.

79 ASTRONOMY AND ASTROPHYSICS↗

Fluctuation Dynamo in a Collisionless, Weakly Magnetized Plasma

Results from a numerical study of fluctuation dynamo in a collisionless, weakly magnetized plasma are presented. The key difference between this dynamo and its magnetohydrodynamic (MHD) counterpart is the adiabatic production of magnetic-field-aligned pressure anisotropy by the amplification of a weak seed field. This, in turn, drives kinetic instabilities on the ion-Larmor scale—namely, firehose and mirror—which sever the adiabatic link between the thermal and magnetic pressures, thereby allowing the dynamo to proceed. After an initial phase of rapid growth driven by these instabilities, the magnetic energy grows exponentially and exhibits a ${k}^{3/2}$ spectrum that peaks near the resistive scale, similar to the large-magnetic-Prandtl-number ($\mathrm{Pm}\gg 1$) MHD dynamo. The magnetic field self-organizes into a folded-sheet topology, with direction reversals at the resistive scale and field lines curved at the parallel scale of the flow. The effective $\mathrm{Pm}$ is determined by whether the ion-Larmor scale is above or below the field-reversing scale: in the former case, particles undergo Bohm-like diffusion; in the latter case, particles scatter primarily off of firehose fluctuations residing at the ends of the magnetic folds, and the viscosity becomes anisotropic. The magnetic field ultimately saturates at dynamical strengths, with its spectral peak migrating toward larger scales. This feature, along with an anti-correlation of magnetic-field strength and field-line curvature and a gradual thinning of magnetic sheets into ribbons, resembles the saturated state of the large-$\mathrm{Pm}$ dynamo, the primary differences manifesting in firehose/mirror-unstable regions. Furthermore, these results have implications for magnetic-field growth in the weakly collisional intracluster medium of galaxy clusters.

79 ASTRONOMY AND ASTROPHYSICS↗