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At least 1,405 records · Page 78

An investigation into factors affecting the precision of CT radiation dose profile width measurements using radiochromic films

Purpose: To investigate the impact of x-ray beam energy, exposure intensity, and flat-bed scanner uniformity and spatial resolution on the precision of computed tomography (CT) beam width measurements using Gafchromic XR-QA2 film and an off-the-shelf document scanner. Methods: Small strips of Gafchromic film were placed at isocenter in a CT scanner and exposed at various x-ray beam energies (80–140 kVp), exposure levels (50–400 mA s), and nominal beam widths (1.25, 5, and 10 mm). The films were scanned in reflection mode on a Ricoh MP3501 flat-bed document scanner using several spatial resolution settings (100 to 400 dpi) and at different locations on the scanner bed. Reflection measurements were captured in digital image files and radiation dose profiles generated by converting the image pixel values to air kerma through film calibration. Beam widths were characterized by full width at half maximum (FWHM) and full width at tenth maximum (FWTM) of dose profiles. Dependences of these parameters on the above factors were quantified in percentage change from the baselines. Results: The uncertainties in both FWHM and FWTM caused by varying beam energy, exposure level, and scanner uniformity were all within 4.5% and 7.6%, respectively. Increasing scanner spatial resolution significantly increased the uncertainty in both FWHM and FWTM, with FWTM affected by almost 8 times more than FWHM (48.7% vs 6.5%). When uncalibrated dose profiles were used, FWHM and FWTM were over-estimated by 11.6% and 7.6%, respectively. Narrower beam width appeared more sensitive to the film calibration than the wider ones (R{sup 2} = 0.68 and 0.85 for FWHM and FWTM, respectively). The global and maximum local background variations of the document scanner were 1.2%. The intrinsic film nonuniformity for an unexposed film was 0.3%. Conclusions: Measurement of CT beam widths using Gafchromic XR-QA2 films is robust against x-ray energy, exposure level, and scanner uniformity. With proper film calibration and scanner resolution setting, it can provide adequate precision for meeting ACR and manufacturer’s tolerances for the measurement of CT dose profiles.

60 APPLIED LIFE SCIENCES↗

Collective Thomson scattering of a high power electron cyclotron resonance heating beam in LHD (invited)

Collective Thomson scattering (CTS) system has been constructed at LHD making use of the high power electron cyclotron resonance heating (ECRH) system in Large Helical Device (LHD). The necessary features for CTS, high power probing beams and receiving beams, both with well defined Gaussian profile and with the fine controllability, are endowed in the ECRH system. The 32 channel radiometer with sharp notch filter at the front end is attached to the ECRH system transmission line as a CTS receiver. The validation of the CTS signal is performed by scanning the scattering volume. A new method to separate the CTS signal from background electron cyclotron emission is developed and applied to derive the bulk and high energy ion components for several combinations of neutral beam heated plasmas.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

SU-F-T-468: Efficient Scanning Data Analysis for TomoTherapy

Purpose: The standard TomoTherapy 2D scanning system requires manual analysis using spreadsheets or similar software. Manual analysis is time consuming and does not allow efficient use of the medical physicist or timely results that may indicate issues during the acquisition of data. The purpose of this study is to determine if an in-house solution can provide timely analysis of TomoTherapy scan data. Methods: A custom MATLAB program utilizing a streamlined graphical interface was developed to interpret the native scanning data acquired by the TomoTherapy Electrometer Measurement System (TEMS). The gold beam data provided by the manufacturer was used as a baseline for the acquired data. Two separate sets of scan data were used including longitudinal, transverse, and percent depth dose (PDD). The scan data were compared visually in an overlay and analytically for each beam width using the full width half max (FWHM) for longitudinal profiles and difference inside the field core for the transverse profiles as recommended by TG-148. A plot of the PDD percent error at each point along the curve was generated to show agreement. The time to analysis was measured on a laptop running an Intel i5 processor with 8GB of RAM. Results: The software program required on average less than 5 seconds to load and analyze the results. No conversion or reformatting of the data was required. This allowed real-time visualization of the comparison to the gold beam data as well as the parameters recommended by TG-148. The average percent difference was 0.3% for the longitudinal profiles and 0.1% for the transverse profiles. All PDD data was less than 1% different beyond dmax. Conclusion: We have developed a tool to analyze TomoTherapy scan data in real-time. This allows an efficient method to perform beam commissioning, annual QA, and adjust the beam parameters if necessary.

61 RADIATION PROTECTION AND DOSIMETRY↗

A 405-MHz, 5-beam phased array antenna

The Wave Propagation Lab. has completed the design and construction of a phased array antenna for use at 405.25 MHz for atmospheric wind profiling. The steering geometry of the sequentially switched beam is shown. The Yagi-Uda antenna elements are arranged on a square grid whose axes are 45 deg with respect to the cardinal directions. By constraining the phase difference between rows of identically phased elements to an even, integral submultiple of 360 deg, symmetries appear in the phasing maps which reduce the switching hardware. The vertical beam is generated by switching around the four beam circuitry which results in identical phasing on all of the elements. After the 18 signals are synthesized they are split and distributed about the array while maintaining proper phasing because of the symmetries. Computer simulations were employed in the design process.

Law, D. C.↗

Low profile antennas for MSAT applications

For MSAT applications, a number of different antennas have been designed and investigated. They include low gain omnidirectional antennas and medium gain to high gain directional antennas. The latter include both portable and vehicular antennas. While portable units are desirable to be low profile and low cost, the vehicular antennas have proved to be the most challenging antenna types for the mobile satellite application. The results of our efforts in design of such antennas are described briefly. Low profile designs are emphasized in most cases, and microstrip type radiators are therefore selected. The single radiator provides low gain omnidirectional patterns and is optimized for low cost applications. It provides low gains around 2-6 dBic and is useful mostly for the data transmission. Medium to high gain antennas are developed as arrays of omnidirectional elements. Again, different designs are optimized to meet the needs of different applications. For portable units, the array configuration can be flexible and is optimized for maximum broadside gains. For vehicular units, however the configurations are desirable to be low profile, or compact, and have means for scanning the antenna beam. For simplicity, fixed beam antennas with mechanical beam scan are selected. For these antennas, as well, different designs, having low profile or compact size, are selected and optimized to meet the MSAT gain and G/T requirements.

Shafai, L.↗

Measurement of electric field across individual wurtzite GaN quantum dots using electron holography

Electrostatic potential profiles across wurtzite AlN/GaN quantum dot (QD) superlattices grown by molecular beam epitaxy have been measured using off-axis electron holography. The profiles for individual GaN QDs show large phase shifts which can be understood in terms of spontaneous polarization and piezoelectric fields and the accumulation of positive and negative charge at the GaN/AlN interfaces. An electric field with magnitude of {approx}7.8 {+-} 2 MV/cm was measured across the center of a GaN QD, in reasonable agreement with reported simulations.

36 MATERIALS SCIENCE↗

SU-G-JeP1-13: Innovative Tracking Detector for Dose Monitoring in Hadron Therapy: Realization and Monte Carlo Simulations

Purpose: Development of strategies to monitor range uncertainties is necessary to improve treatment planning in Charged Particle Therapy (CPT) and fully exploit the advantages of ion beams. Our group developed (within the framework of the INSIDE project funded by the Italian research ministry) and is currently building a compact detector Dose Profiler (DP) able to backtrack charged secondary particles produced in the patient during the irradiation. Furthermore we are studying monitoring strategy exploiting charged secondary emission profiles to control the range of the ion beam. Methods: This contribution reports on the DP detector design and construction status. The detector consists of a charged secondary tracker composed of scintillating fiber layers and a LYSO calorimeter for particles energy measurement.The detector layout has been optimized using the FLUKA Monte Carlo (MC) simulation software. The simulation of a 220 MeV Carbon beam impinging on a PMMA target has been performed to study the detector response, exploiting previous secondary radiation measurements performed by our group. The emission profile of charged secondary particles was reconstructed backtracking the particles to their generation point to benchmark the DP performances. Results: The DP construction status, including the technological details will be presented. The feasibility of range monitoring with DP will be demonstrated by means of MC studies. The correlation of the charged secondary particles emission shape with the position of the Bragg peak (BP) will be shown, as well as the spatial resolution achievable on the BP position estimation (less than 3 mm) in the clinical like conditions. Conclusion: The simulation studies supported the feasibility of an accurate range monitoring technique exploiting the use of charged secondary fragments emitted during the particle therapy treatment. The DP experimental tests are foreseen in 2016, at CNAO particle therapy center in Pavia.

60 APPLIED LIFE SCIENCES↗

SU-E-J-222: Feasibility Study of MRI-Only Proton Therapy Planning

Purpose: To assess the dosimetric equivalence of MRI based proton planning vs. single energy x-ray CT. Methods: 8 glioblastoma patients were imaged with CT and MRI after surgical resection. T1-weighted 3DMPRAGE was used to delineate the GTV, which was subsequently rigidly registered to the CT volume. A pseudoCT was generated from the aligned MRI by combining segmentation and atlas-based approaches. The spatial resolution both for pseudo- and real CT was 0.6×0.6×2.5mm. Three orthogonal proton beams were simulated on the pseudoCT. Two co-planar beams were set on the axial plane. The third one was planned parallel to the cranio-caudal (CC) direction. Each beam was set to cover the GTV at 98% of the nominal dose (18Gy). The proton plan was copied and transferred to the real CT, including aperture/compensator geometry. Dose comparison between pseudoCT and CT plan was performed beam-by-beam by quantifying the range shift of dose profile on each slice of the GTV. The GTV’s V{sub 98} was computed for the CT. Results: For beams in axial plane the median absolute value of the range shift was 0.3mm, with 0.9mm and 1.4mm as 95th percentile and maximum, respectively. Worst scenarios were found for the CC beam, where we measured 1.1mm (median), 2.7mm (95thpercentile) and 5mm (maximum). Regardless the direction, beams passing through the surgical site, where metal (Titanium MRI-compatible) staples were present, were mostly affected by range shift. GTV’s V{sub 98} for CT was not lower than 99.3%. Conclusion: The study showed the clinical feasibility of an MRI-alone proton plan. Advantages include the possibility to rely on better soft tissue contrast for target and organs at risk delineation without the need of further CT scan and image registration. Additional investigation is required in presence of metal implants along the beam path and to account for partial volume effects due to slice thickness.

60 APPLIED LIFE SCIENCES↗

TU-AB-BRC-11: Moving a GPU-OpenCL-Based Monte Carlo (MC) Dose Engine Towards Routine Clinical Use: Automatic Beam Commissioning and Efficient Source Sampling

Purpose: We have previously developed a GPU-OpenCL-based MC dose engine named goMC with built-in analytical linac beam model. To move goMC towards routine clinical use, we have developed an automatic beam-commissioning method, and an efficient source sampling strategy to facilitate dose calculations for real treatment plans. Methods: Our commissioning method is to automatically adjust the relative weights among the sub-sources, through an optimization process minimizing the discrepancies between calculated dose and measurements. Six models built for Varian Truebeam linac photon beams (6MV, 10MV, 15MV, 18MV, 6MVFFF, 10MVFFF) were commissioned using measurement data acquired at our institution. To facilitate dose calculations for real treatment plans, we employed inverse sampling method to efficiently incorporate MLC leaf-sequencing into source sampling. Specifically, instead of sampling source particles control-point by control-point and rejecting the particles blocked by MLC, we assigned a control-point index to each sampled source particle, according to MLC leaf-open duration of each control-point at the pixel where the particle intersects the iso-center plane. Results: Our auto-commissioning method decreased distance-to-agreement (DTA) of depth dose at build-up regions by 36.2% averagely, making it within 1mm. Lateral profiles were better matched for all beams, with biggest improvement found at 15MV for which root-mean-square difference was reduced from 1.44% to 0.50%. Maximum differences of output factors were reduced to less than 0.7% for all beams, with largest decrease being from1.70% to 0.37% found at 10FFF. Our new sampling strategy was tested on a Head&Neck VMAT patient case. Achieving clinically acceptable accuracy, the new strategy could reduce the required history number by a factor of ∼2.8 given a statistical uncertainty level and hence achieve a similar speed-up factor. Conclusion: Our studies have demonstrated the feasibility and effectiveness of our auto-commissioning approach and new efficient source sampling strategy, implying the potential of our GPU-based MC dose engine goMC for routine clinical use.

61 RADIATION PROTECTION AND DOSIMETRY↗

Self-focusing and compression of laser pulses in partially stripped plasma

Propagation of a laser beam, having radial and axial Gaussian profile, in partially stripped plasma is analyzed. A wave equation, for the laser electric field driven by linear as well as nonlinear contributions due to atoms and plasma electrons, has been set up. A variational technique is used to obtain equations describing the evolution of the laser spot size and pulse length, and numerical methods are used to study their simultaneous evolution in partially stripped plasma.

43 PARTICLE ACCELERATORS↗

Importance of the Rotational Transform for L–H Transitions in the TJ-II Stellarator

We study the effect of the rotational transform profile on the L–H confinement transitions in the neutral beam-heated plasmas in the TJ-II stellarator. The rotational transform profile in the vacuum is determined by the external coil currents but is modified by the plasma current, Ip. We find that L–H confinement transitions systematically occur when the configuration and plasma current are such that a low-order rational is placed in the plasma edge region, with a distribution centered around ρ=0.8±0.05. It is suggested that magnetohydrodynamic turbulence plays an important role in triggering the L–H transitions at TJ-II.

van Milligen, Boudewijn Philip (ORCID:000000015344↗

Laser System for Livermore's Mono Energetic Gamma-Ray Source

A Mono-energetic Gamma-ray (MEGa-ray) source, based on Compton scattering of a high-intensity laser beam off a highly relativistic electron beam, requires highly specialized laser systems. To minimize the bandwidth of the {gamma}-ray beam, the scattering laser must have minimal bandwidth, but also match the electron beam depth of focus in length. This requires a {approx}1 J, 10 ps, fourier-transform-limited laser system. Also required is a high-brightness electron beam, best provided by a photoinjector. This electron source requires a second laser system with stringent requirements on the beam including flat transverse and longitudinal profiles and fast rise times. Furthermore, these systems must be synchronized to each other with ps-scale accuracy. Using a novel hyper-dispersion compressor configuration and advanced fiber amplifiers and diode-pumped Nd:YAG amplifiers, we have designed laser systems that meet these challenges for the X-band photoinjector and Compton-scattering source being built at Lawrence Livermore National Laboratory.

42 ENGINEERING↗

XeCl excimer laser with new prism resonator configurations and its performance characteristics

New resonator cavity configurations, namely, the prism resonator and unstable prism resonator, are demonstrated for the first time in an excimer (XeCl) laser with interesting and novel results. High misalignment tolerance ∼50 mrad is achieved with considerably reduced beam divergence of less than ∼1 mrad without reduction in output power capabilities of the laser. The misalignment tolerance of ∼50 mrad is a dramatic improvement of ∼25 times compared to ∼2 mrad normally observed in standard excimer laser with plane-plane cavity. Increase in depth of focus from 3 mm to 5.5 mm was also achieved in case of prism resonator configuration with an improvement of about 60%. Unstable prism resonator configuration is demonstrated here in this paper with further reduction in beam divergence to about 0.5 mrad using plano-convex lens as output coupler. The misalignment tolerance in case of unstable prism resonator was retained at about 30 mrad which is a high value compared to standard unstable resonators. The output beam spot was completely filled with flat-top profile with prism resonator configurations, which is desired for various material processing applications. Focusing properties and beam divergence in case of prism resonator have been investigated using SEM (scanning electron microscope) images. SEM images of the focused spot size (∼20 μm holes) on metal sheet indicate beam divergence of about 0.05 mrad which is about 1.5 times diffraction limit. Energy contained in this angle is thus sufficient for micro-machining applications. Clean and sharp edges of the micro-holes show high pointing stability with multiple shot exposures. Such characteristics of the excimer laser system will be extremely useful in micro-machining and other field applications.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Monitoring Spacecraft Telemetry Via Optical or RF Link

A patent disclosure document discusses a photonic method for connecting a spacecraft with a launch vehicle upper-stage telemetry system as a means for monitoring a spacecraft fs health and status during and right after separation and deployment. This method also provides an efficient opto-coupled capability for prelaunch built-in-test (BIT) on the ground to enable more efficient and timely integration, preflight checkout, and a means to obviate any local EMI (electromagnetic interference) during integration and test. Additional utility can be envisioned for BIT on other platforms, such as the International Space Station (ISS). The photonic telemetry system implements an optical free-space link with a divergent laser transmitter beam spoiled over a significant cone angle to accommodate changes in spacecraft position without having to angle track it during deployment. Since the spacecraft may lose attitude control and tumble during deployment, the transmitted laser beam interrogates any one of several low-profile meso-scale retro-reflective spatial light modulators (SLMs) deployed over the surface of the spacecraft. The return signal beam, modulated by the SLMs, contains health, status, and attitude information received back at the launch vehicle. Very compact low-power opto-coupler technology already exists for the received signal (requiring relatively low bandwidths, e.g., .200 kbps) to enable transfer to a forward pass RF relay from the launch vehicle to TDRSS (Tracking and Data Relay Satellite System) or another recipient. The link would be active during separation and post-separation to monitor spacecraft health, status, attitude, or other data inventories until attitude recovery and ground control can be re-established. An optical link would not interfere with the existing upper stage telemetry and beacon systems, thus meeting launch vehicle EMI environmental constraints.

Fielhauer, K. B.↗

Perturbative representation of ultrashort nonparaxial elegant Laguerre-Gaussian fields

An analytical method for calculating the electromagnetic fields of a nonparaxial elegant Laguerre-Gaussian (LG) vortex beam is presented for arbitrary pulse duration, spot size, and LG mode. This perturbative approach provides a numerically tractable model for the calculation of arbitrarily high radial and azimuthal LG modes in the nonparaxial regime, without requiring integral representations of the fields. A key feature of this perturbative model is its use of a Poisson-like frequency spectrum, which allows for the proper description of pulses of arbitrarily short duration. Lastly, this model is thus appropriate for simulating laser-matter interactions, including those involving short laser pulses.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

SU-E-T-101: An Arc Based Treatment Technique for Proton PBS Beam Utilizing Overlaid Bragg Peak Spots

Purpose: When Bragg peaks from proton PBS beams are overlaid from a large number of directions, it creates a localized dose distribution with rapid falloff. By positioning these overlaid Bragg peak (OBP) spots strategically throughout the targeted volume, a uniform and conformal dose distribution can be achieved. When PBS spots from all the directions are delivered in an arc fashion, it becomes the Volume Modulated Proton Therapy (VMPT) technique which corresponds to the VMAT technique in photon therapy. Methods: PBS beam from an IBA machine and a 20cm radius cylindrical phantom were simulated with GATE/GEANT4. To position the OBP spot at the center of the phantom, single energy PBS beam from 10/36/360 equally-spaced directions around the phantom was used. To position the OBP spot at an off-center position, PBS beams with various energies were used. To form a uniform dose distribution in 1D/2D, OBP spots are positioned in arrays with spot intervals and weight optimized. Results: Dose profile for single energy OBP spot improved when the number of beam angles increased from 10 to 36, but remained same from 36 to 360 angles. Multi-energy OBP spot had a slightly non-symmetrical profile due to the different energy proton beams used. By optimizing each OBP spot’s weight, 11 OBP spots with 10mm interval size created a uniform dose distribution covering a length of 10cm. Similarly, 11×11 OBP spots in an array of 10mm interval size created a uniform dose distribution covering an area of 10×10cm{sup 2}. Conclusion: We demonstrated the technique of using OBP spots to deliver uniform dose in 1D/2D. This technique can be easily extended through the optimization of position and weight of OBP spots in 3D and becomes the arc based VMPT technique. Further studies are needed to explore the optimization methods and full potential of the VMPT technique.

60 APPLIED LIFE SCIENCES↗

Electron beam-plasma interaction in a dusty plasma with excess suprathermal electrons

The existence of large-amplitude electron-acoustic solitary structures is investigated in an unmagnetized and collisionless two-temperature dusty plasma penetrated by an electron beam. A nonlinear pseudopotential technique is used to investigate the occurrence of stationary-profile solitary waves, and their parametric dependence on the electron beam and dust perturbation is discussed.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗