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At least 1,423 records · Page 79

Precision Measurement of the Eta Radiative Decay Width via the Primakoff Effect with GlueX

The GlueX detector in the experimental Hall-D at Jefferson Lab provides a unique capability to perform a measurement of the eta to gamma gamma decay width via the Primakoff effect with the precision significantly better than all existing collider and Primakoff results. The experiment will measure differential cross sections of eta mesons at forward angles on a liquid hydrogen and helium targets using a beam of tagged photons, which will be used for the extraction of the decay width. The measurement is essential for the determination of the fundamental properties such as the ratios of the light quark masses and the eta eta-prime mixing angle, and will provide an important test of chiral symmetry breaking in QCD. The experimental results will also allow to significantly reduce uncertainties on partial widths of all other eta decays. We will give an overview the PrimEx-D physics program and experimental setup.

Somov, Alexander↗

Development of an engineering model atmosphere for Mars

An engineering model atmosphere for Mars is being developed with many of the same features and capabilities for the highly successful Global Reference Atmospheric Model (GRAM) program for Earth's atmosphere. As an initial approach, the model is being built around the Martian atmosphere model computer subroutine (ATMOS) of Culp and Stewart (1984). In a longer-term program of research, additional refinements and modifications will be included. ATMOS includes parameterizations to stimulate the effects of solar activity, seasonal variation, diurnal variation magnitude, dust storm effects, and effects due to the orbital position of Mars. One of the current shortcomings of ATMOS is the neglect of surface variation effects. The longer-term period of research and model building is to address some of these problem areas and provide further improvements in the model (including improved representation of near-surface variations, improved latitude-longitude gradient representation, effects of the large annual variation in surface pressure because of differential condensation/sublimation of the CO2 atmosphere in the polar caps, and effects of Martian atmospheric wave perturbations on the magnitude of the expected density perturbation.

Justus, C. G.↗

Findings From 9 Years of Renal Stone Surveillance of U.S. Astronauts

INTRODUCTION: Renal stones are thought to be a risk for spaceflight due to urine chemistry changes, induced by microgravity. Asymptomatic stone can have significant medical and mission impact.For9 years astronauts travelling to the International Space Station (ISS) have received pre-and post-flight renal ultrasound, according to a specialized renal ultrasound protocol, to look for renal calcifications or mineralized renal material (MRM).A new ultrasound machine was put in service halfway through the screening program. METHODS: MRM screening data from pre-and post-flight were compared, to look for changes in MRM burden. Pre-and post-flight scans from 42 subjects were compared. Studies were further stratified by old versus new machine. Measures were modeled using the analysis of variance (ANOVA) as defined by the interaction between pre-to postflight, and machine-to-machine. RESULTS: There was no observed statistical change seen in MRM burden pre-to postflight using the new higher-resolution ultrasound machine. DISCUSSION: The new machine gives more precise measurements and allows us to differentiate MRMs from other bright objects seen on ultrasound, such as small blood vessels. These data imply that spaceflight does not increase the risk of renal stone formation, at least out to the length of ISS missions. This data will be used to update NASA’s Human System Risk Board’s risk tracking documents, in-flight Concept of Operations, and our Clinical Practice Guideline.

K Cortez↗

Exclusive single pion electroproduction off the proton: Results from CLAS

Exclusive meson electroproduction off protons is a powerful tool to probe the effective degrees of freedom in excited nucleon states at the varying distance scale where the transition from the contributions of both quark core and meson-baryon cloud to the quark core dominance. During the past decade, the CLAS collaboration has executed a broad experimental program to study the excited states of the proton using polarized electron beam and both polarized and unpolarized proton targets. The measurements covered a broad kinematic range in the invariant mass $W$ and photon virtuality $Q^2$ with nearly full coverage in polar and azimuthal angles in the hadronic CM system. As results, several low-lying nucleon resonance states in particular from pion threshold to $W < 1.6$ GeV have been explored. These include $\Delta$(1232)$\frac{3}{2}^+$, $N(1440)\frac{1}{2}^+$, $N(1520)\frac{3}{2}^-$, and $N(1535)\frac{1}{2}^-$ states. In addition, we recently published the differential cross sections and helicity amplitudes of the reaction $\gamma^*p\to n\pi^+$ at higher $W$ (1.6 to 2.0 GeV) which are the $N(1675)\frac{5}{2}^-$, $N(1680)\frac{5}{2}^+$, and $N(1710)\frac{1}{2}^+$ states. These excited states with isospin $1/2$ and with masses near 1.7 GeV can be accessed in single $n\pi^+$ production as there are no isospin $3/2$ states present in this mass range with the same spin-parity assignments. As a result, I will briefly discuss these states from CLAS results of the single charged pion electroproduction data.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Fast Approximate Union Volume in High Dimensions with Line Samples

The classical problem of calculating the volume of the union of d-dimensional balls is known as "Union Volume." We present line-sampling approximation algorithms for Union Volume. Our methods may be extended to other Boolean operations, such as setminus; or to other shapes, such as hyper-rectangles. The deterministic, exact approaches for Union Volume do not scale well to high dimensions. However, we adapt several of these exact approaches to approximation algorithms based on sampling. We perform local sampling within each ball using lines. We have several variations, depending on how the overlapping volume is partitioned, and depending on whether radial, axis-aligned, or other line patterns are used. Our variations fall within the family of Monte Carlo sampling, and hence have about the same theoretical convergence rate, 1 /$\sqrt{M}$, where M is the number of samples. In our limited experiments, line-sampling proved more accurate per unit work than point samples, because a line sample provides more information, and the analytic equation for a sphere makes the calculation almost as fast. We performed a limited empirical study of the efficiency of these variations. We suggest a more extensive study for future work. We speculate that different ball arrangements, differentiated by the distribution of overlaps in terms of volume and degree, will benefit the most from patterns of line samples that preferentially capture those overlaps. Acknowledgement We thank Karl Bringman for explaining his BF-ApproxUnion (ApproxUnion) algorithm [3] to us. We thank Josiah Manson for pointing out that spoke darts oversample the center and we might get a better answer by uniform sampling. We thank Vijay Natarajan for suggesting random chord sampling. The authors are grateful to Brian Adams, Keith Dalbey, and Vicente Romero for useful technical discussions. This work was sponsored by the Laboratory Directed Research and Development (LDRD) Program at Sandia National Laboratories. This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of Advanced Scientific Computing Research (ASCR), Applied Mathematics Program. Sandia National Laboratories is a multi-mission laboratory managed and operated by National Technology and Engineering Solutions of Sandia, LLC., a wholly owned subsidiary of Honeywell International, Inc., for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-NA0003525.

97 MATHEMATICS AND COMPUTING↗

Exclusive Single Pion off the Proton: Results from CLAS

Exclusive meson electroproduction off protons is a powerful tool to probe the effective degrees of freedom in excited nucleon states at the varying distance scale where the transition from the contributions of both quark core and meson-baryon cloud to the quark core dominance. During the past decade, the CLAS collaboration has executed a broad experimental program to study the excited states of the proton using polarized electron beam and both polarized and unpolarized proton targets. The measurements covered a broad kinematic range in the invariant mass $W$ and photon virtuality $Q^2$ with nearly full coverage in polar and azimuthal angles in the hadronic CM system. As results, several low-lying nucleon resonance states in particular from pion threshold to $W < 1.6$ GeV have been explored. These include $\Delta$(1232)$\frac{3}{2}^+$, $N(1440)\frac{1}{2}^+$, $N(1520)\frac{3}{2}^-$, and $N(1535)\frac{1}{2}^-$ states. In addition, we recently published the differential cross sections and helicity amplitudes of the reaction $\gamma^*p\to n\pi^+$ at higher $W$ (1.6 to 2.0 GeV) which are the $N(1675)\frac{5}{2}^-$, $N(1680)\frac{5}{2}^+$, and $N(1710)\frac{1}{2}^+$ states. These excited states with isospin $1/2$ and with masses near 1.7 GeV can be accessed in single $n\pi^+$ production as there are no isospin $3/2$ states present in this mass range with the same spin-parity assignments. As a result, I will briefly discuss these states from CLAS results of the single charged pion electroproduction data.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Automated fiber placement composite manufacturing: The mission at MSFC's Productivity Enhancement Complex

Automated fiber placement is a manufacturing process used for producing complex composite structures. It is a notable leap to the state-of-the-art in technology for automated composite manufacturing. The fiber placement capability was established at the Marshall Space Flight Center's (MSFC) Productivity Enhancement Complex in 1992 in collaboration with Thiokol Corporation to provide materials and processes research and development, and to fabricate components for many of the Center's Programs. The Fiber Placement System (FPX) was developed as a distinct solution to problems inherent to other automated composite manufacturing systems. This equipment provides unique capabilities to build composite parts in complex 3-D shapes with concave and other asymmetrical configurations. Components with complex geometries and localized reinforcements usually require labor intensive efforts resulting in expensive, less reproducible components; the fiber placement system has the features necessary to overcome these conditions. The mechanical systems of the equipment have the motion characteristics of a filament winder and the fiber lay-up attributes of a tape laying machine, with the additional capabilities of differential tow payout speeds, compaction and cut-restart to selectively place the correct number of fibers where the design dictates. This capability will produce a repeatable process resulting in lower cost and improved quality and reliability.

Vickers, John H.↗

Microgravity modifies protein kinase C isoform translocation in the human monocytic cell line U937 and human peripheral blood T-cells

Individual protein kinase C (PKC) isoforms fulfill distinct roles in the regulation of the commitment to differentiation, cell cycle arrest, and apoptosis in both monocytes and T-cells. The human monocyte like cell line U937 and T-cells were exposed to microgravity, during spaceflight and the translocation (a critical step in PKC signaling) of individual isoforms to cell particulate fraction examined. PKC activating phorbol esters induced a rapid translocation of several PKC isoforms to the particulate fraction of U937 monocytes under terrestrial gravity (1 g) conditions in the laboratory. In microgravity, the translocation of PKC beta II, delta, and epsilon in response to phorbol esters was reduced in microgravity compared to 1 g, but was enhanced in weak hypergravity (1.4 g). All isoforms showed a net increase in particulate PKC following phorbol ester stimulation, except PKC delta which showed a net decrease in microgravity. In T-cells, phorbol ester induced translocation of PKC delta was reduced in microgravity, compared to 1 g, while PKC beta II translocation was not significantly different at the two g-levels. These data show that microgravity differentially alters the translocation of individual PKC isoforms in monocytes and T-cells, thus providing a partial explanation for the modifications previously observed in the activation of these cell types under microgravity.

STS-81 Shuttle Project↗

Juxtatumoral perinephric fat analysis in clear cell renal cell carcinoma

Purpose: The purpose of the study was to evaluate the feasibility of using contrast-enhanced computed tomography (CECT)-based texture analysis (CTTA) metrics to differentiate between juxtatumoral perinephric fat (JPF) surrounding low-grade (ISUP 1–2) versus high-grade (ISUP 3–4) clear cell renal cell carcinoma (ccRCC). Methods: In this IRB-approved study, we retrospectively queried the surgical database between June 2009 and April 2016 and identified 83 patients with pathologically confirmed ccRCC (low grade: n = 54, mean age = 61.5 years, 18F/35M; high grade n = 30, mean age = 61.7 years, 8F/22M) who also had pre-operative multiphase CT acquisitions. CT images were transferred to a 3D workstation, and nephrographic phase JPF regions were manually segmented. Using an in-house developed Matlab program, a CTTA panel comprising of texture metrics extracted using six different methods, histogram, 2D- and 3D-Gray-level co-occurrence matrix (GLCM) and Gray-level difference matrix (GLDM), and 2D-Fast Fourier Transform (FFT) analyses, was applied to the segmented images to assess JPF textural heterogeneity in low- versus high-grade ccRCC. Univariate analysis and receiver-operator characteristics (ROC) analysis were used to assess interclass differences in texture metrics and their prediction accuracy, respectively. Results: All methods except GLCM consistently revealed increased heterogeneity in the JPF surrounding high- versus low-grade ccRCC. FFT showed increased complexity index (p < 0.01). Histogram analysis showed increased kurtosis and positive skewness in (p < 0.03), and GLDM analysis showed decreased measure of correlation coefficient (MCC) (p < 0.04). Several of the GLCM metrics showed statistically significant (p < 0.04) textural differences between the two groups, but with no consistent trend. ROC analysis showed that MCC in GLCM analysis had an area under the curve of 0.75. Conclusions: Our study suggests that CTTA of ccRCC shows statistically significant textural differences in JPF surrounding high- versus low-grade ccRCC.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Pre-Combustion Carbon Capture by a Nanoporous, Superhydrophobic Membrane Contactor Process

This report summarizes progress made during Phase I and Phase II of the project: "Pre-Combustion Carbon Capture by a Nanoporous, Superhydrophobic Membrane Contactor Process," under contract DE-FE-0000646. The objective of this project is to develop a practical and cost effective technology for CO 2 separation and capture for pre-combustion coal-based gasification plants using a membrane contactor/solvent absorption process. The goals of this technology development project are to separate and capture at least 90% of the CO 2 from Integrated Gasification Combined Cycle (IGCC) power plants with less than 10% increase in the cost of energy services. Unlike conventional gas separation membranes, the membrane contactor is a novel gas separation process based on the gas/liquid membrane concept. The membrane contactor is an advanced mass transfer device that operates with liquid on one side of the membrane and gas on the other. The membrane contactor can operate with pressures that are almost the same on both sides of the membrane, whereas the gas separation membranes use the differential pressure across the membrane as driving force for separation. The driving force for separation for the membrane contactor process is the chemical potential difference of CO 2 in the gas phase and in the absorption liquid. This process is thus easily tailored to suit the needs for pre-combustion separation and capture of CO 2 . Gas Technology Institute (GTI) and PoroGen Corporation (PGC) have developed a novel hollow fiber membrane technology that is based on chemically and thermally resistant commercial engineered polymer poly(ether ether ketone) or PEEK. The PEEK membrane material used in the membrane contactor during this technology development program is a high temperature engineered plastic that is virtually non-destructible under the operating conditions encountered in typical gas absorption applications. It can withstand contact with most of the common treating solvents. GTI and PGC have developed a nanoporous and superhydrophobic PEEK-based hollow fiber membrane contactor tailored for the membrane contactor/solvent absorption application for syngas cleanup. The membrane contactor modules were scaled up to 8-inch diameter commercial size modules. We have performing extensive laboratory and bench testing using pure gases, simulated water-gas-shifted (WGS) syngas stream, and a slipstream from a gasification derived syngas from GTI's Flex-Fuel Test Facility (FFTF) gasification plant under commercially relevant conditions. The team have also carried out an engineering and economic analysis of the membrane contactor process to evaluate the economics of this technology and its commercial potential. Our test results have shown that 90% CO 2 capture can be achieved with several physical solvents such as water and chilled methanol. The rate of CO 2 removal by the membrane contactor is in the range of 1.5 to 2.0 kg/m 2 /hr depending on the operating pressures and temperatures and depending on the solvents used. The final economic analysis has shown that the membrane contactor process will cause the cost of electricity to increase by 21% from the base plant without CO 2 capture. The goal of 10% increase in levelized cost of electricity (LCOE) from base DOE Case 1(base plant without capture) is not achieved by using the membrane contactor. However, the 21% increase in LCOE is a substantial improvement as compared with the 31.6% increase in LCOE as in DOE Case 2(state of art capture technology using 2-stages of Selexol TM ).

01 COAL, LIGNITE, AND PEAT↗

Geophysical aspects of remote sensing

Results obtained through the NASA Earth Resources Aircraft Program at Mill Creek, Oklahoma, provide a case history example of the application of remote sensing to the identification of geologic rock units. Thermal infrared images are interpreted by means of a sequence of models of increasing complexity. The roles of various parameters are examined: rock properties (thermal inertia, albedo, emissivity), site location (latitude), season (sun's declination), atmospheric effects (cloud cover, transmission, air temperature), and topographic orientation (slope, azimuth). The results obtained at this site also illustrate the development of an important application of remote sensing in geologic identification. Relatively pure limestones and dolomites of the Mill Creek test area can be differentiated in nighttime infrared images, and facies changes between them can be detected along and across strike. The predominance on the earth's surface of sedimentary rocks, of which limestone and dolomite are major members, indicates the importance of this discrimination.

Watson, K.↗

The effects of simulated hypogravity on murine bone marrow cells

Mouse bone marrow cells grown in complete medium at unit gravity were compared with a similar population cultured in conditions that mimic some aspects of microgravity. After the cells adjusted to the conditions that simulated microgravity, they proliferated as fetal or oncogenic populations; their numbers doubled in twelve hour periods. Differentiated subpopulations were depleted from the heterogeneous mixture with time and the undifferentiated hematopoietic stem cells increased in numbers. The cells in the control groups in unit gravity and those in the bioreactors in conditions of microgravity were monitored under a number of parameters. Each were phenotyped as to cell surface antigens using a panel of monoclonal antibodies and flow cytometry. Other parameters compared included: pH, glucose uptake, oxygen consumption and carbon-dioxide production. Nuclear DNA was monitored by flow cytometry. Functional responses were studied by mitogenic stimulation by various lectins. The importance of these findings should have relevance to the space program. Cells should behave predictably in zero gravity; specific populations can be eliminated from diverse populations and other populations isolated. The availability of stem cell populations will enhance both bone marrow and gene transplant programs. Stem cells will permit developmental biologists study the paths of hematopoiesis.

Lawless, Desales↗

Determination of Yield in Inconel 718 for Axial-Torsional Loading at Temperatures up to 649 C

An experimental program has been implemented to determine small offset yield loci under axial-torsional loading at elevated temperatures. The nickel-base superalloy Inconel 718 (IN718) was chosen for study due to its common use in aeropropulsion applications. Initial and subsequent yield loci were determined for solutioned IN718 at 23, 371, and 454 C and for aged (precipitation hardened) IN718 at 23 and 649 C. The shape of the initial yield loci for solutioned and aged IN718 agreed well with the von Mises prediction. However, in general, the centers of initial yield loci were eccentric to the origin due to a strength-differential (S-D) effect that increased with temperature. Subsequent yield loci exhibited anisotropic hardening in the form of translation and distortion of the locus. This work shows that it is possible to determine yield surfaces for metallic materials at temperatures up to at least 649 C using multiple probes of a single specimen. The experimental data is first-of-its-kind for a superalloy at these very high temperatures and will facilitate a better understanding of multiaxial material response, eventually leading to improved design tools for engine designers.

Gil, Christopher M.↗

Determination of Yield in Inconel 718 for Axial-Torsional Loading at Temperatures up to 649 C

An experimental program has been implemented to determine small offset yield loci under axial-torsional loading at elevated temperatures. The nickel-base superalloy Inconel 718 (IN718) was chosen for study due to its common use in aeropropulsion applications. Initial and subsequent yield loci were determined for solutioned IN718 at 23, 371, and 454 C and for aged (precipitation hardened) IN718 at 23 and 649 C. The shape of the initial yield loci for solutioned and aged IN718 agreed well with the von Mises prediction. However, in general, the centers of initial yield loci were eccentric to the origin due to a strength-differential (S-D) effect that increased with temperature. Subsequent yield loci exhibited anisotropic hardening in the form of translation and distortion of the locus. This work shows that it is possible to determine yield surfaces for metallic materials at temperatures up to at least 649 C using multiple probes of a single specimen. The experimental data is first-of-its-kind for a superalloy at these very high temperatures and will facilitate a better understanding of multiaxial material response, eventually leading to improved design tools for engine designers.

Gil, Christopher M.↗

Life Sciences Data Archives (LSDA) in the Post-Shuttle Era

Now, more than ever before, NASA is realizing the value and importance of their intellectual assets. Principles of knowledge management-the systematic use and reuse of information, experience, and expertise to achieve a specific goal-are being applied throughout the agency. LSDA is also applying these solutions, which rely on a combination of content and collaboration technologies, to enable research teams to create, capture, share, and harness knowledge to do the things they do well, even better. In the early days of spaceflight, space life sciences data were collected and stored in numerous databases, formats, media-types and geographical locations. These data were largely unknown/unavailable to the research community. The Biomedical Informatics and Health Care Systems Branch of the Space Life Sciences Directorate at JSC and the Data Archive Project at ARC, with funding from the Human Research Program through the Exploration Medical Capability Element, are fulfilling these requirements through the systematic population of the Life Sciences Data Archive. This project constitutes a formal system for the acquisition, archival and distribution of data for HRP-related experiments and investigations. The general goal of the archive is to acquire, preserve, and distribute these data and be responsive to inquiries for the science communities. Information about experiments and data, as well as non-attributable human data and data from other species' are available on our public Web site http://lsda.jsc.nasa.gov. The Web site also includes a repository for biospecimens, and a utilization process. NASA has undertaken an initiative to develop a Shuttle Data Archive repository. The Shuttle program is nearing its end in 2010 and it is critical that the medical and research data related to the Shuttle program be captured, retained, and usable for research, lessons learned, and future mission planning. Communities of practice are groups of people who share a concern or a passion for something they do, and learn how to do it better as they interact regularly. LSDA works with the HRP community of practice to ensure that we are preserving the relevant research and data they need in the LSDA repository. An evidence-based approach to risk management is required in space life sciences. Evidence changes over time. LSDA has a pilot project with Collexis, a new type of Web-based search engine. Collexis differentiates itself from full-text search engines by making use of thesauri for information retrieval. The high-quality search is based on semantics that have been defined in a life sciences ontology. Additionally, Collexis' matching technology is unique, allowing discovery of partially matching dicuments. Users do not have to construct a complicated (Boolean) search query, but can simply enter a free text search without the risk of getting "no results". Collexis may address these issues by virtue of its retrieval and discovery capabilities across multiple repositories.

Fitts, Mary A.↗

Hypervelocity Impact Characterization on Hubble Space Telescope Multi-Layer Insulation

Multi-layer insulation (MLI) is a common material used on rocket bodies and spacecraft to provide thermal regulation. This material is typically attached on the surface of the object in orbit and is thus exposed to the space environment and to micrometeoroid and orbital debris (MMOD) impacts. Occasionally, these exposed surfaces are returned and used by NASA’s Orbital Debris Program Office (ODPO) for analysis. When used to assess impacts on surfaces over time, materials like MLI provide an opportunity for in situ measurements to support the Orbital Debris Engineering Model (ORDEM) development and validation. During the 2009 Hubble Space Telescope (HST) Serving Mission, the MLI blankets covering the HST electronics bays 5, 8, and 10 were removed and subsequently analyzed by the ODPO in 2010. The bay 5 blanket was used in concert with ground-based hypervelocity impact tests on single layer MLI to validate the ORDEM 3.1 computer model of the OD environment, but further research was required to properly differentiate the impact features attributed to MM or OD. The ORDEM 3.1 validation effort identified several areas of further study to improve model validation and understanding of the space environment. Among these topics are the effects of underlying MLI layers on first layer impact feature characteristics, the effects of space weathering and associated damage to the surface on impact feature characteristics, and the transition from perforating to cratering regions. To better understand hypervelocity impact damage and long-term degradation of MLI surfaces, further hypervelocity impact testing was proposed and completed from 2020 to 2022. This paper discusses test conditions and parameters with resultant impact hole analyses of single layer versus multi-layered samples, space-exposed samples versus pristine, equivalent samples, and perforation versus cratering criteria in the difficult transition region. Damage equations, with associated uncertainties, are estimated from the test parameters and presented. The results of a feasibility study are described, in which the Scanning Electron Microscopy/Electron Dispersive X-ray was used to examine the MLI layers to differentiate MM and OD impacts. Finally, the extension of HST MLI outcomes and analysis methodology as it applies to future returned MLI samples is discussed.

Melissa A. Murray↗

Thermophysical Characterization of NUW-LHT-5M Lunar Highland Simulant

NASA's imminent return to the Moon with the Artemis III program necessitates efficient lunar construction and habitation technologies, prompting development of in situ resource utilization (ISRU). Lunar ISRU depends on high-fidelity lunar regolith simulants that must be thermophysically faithful to the Moon. The 5th iteration of the LHT highland simulant series aims to be the best lunar highland simulant to date.

lunar↗