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At least 145 records · Page 8

Advancements in medicine from aerospace research.

Discussion of a NASA-sponsored medical program under which work is done by multidiscipline teams to provide an interface between aerospace and medicine. A prosthetic urethral valve, an ear oximeter for measurement of oxygen content in the blood, a radiation dosimeter and an electromyographic muscle trainer are noted as the products of this program.

Wooten, F. T.↗

Densitography - A new method for evaluation of cardiac performance of rest and during exercise.

The validity of the densitographic curves obtained from the pinna of the ear for measuring the systolic intervals has been investigated in 28 subjects. This technique is found to permit the performance of noninvasive physiologic studies during physical activities, exercise tests, flight conditions, and probably long-term monitoring of critically ill patients. Densitographic curves constitute an excellent substitute by which to measure time-base intervals of the cardiac cycle when the carotid pulse tracing is not available.

Chirife, R.↗

Circadian rhythms of visual accommodation responses and physiological correlations.

Use of a recently developed servocontrolled infrared optometer to continuously record the state of monocular focus while subjects viewed a visual target for which the stimulus to focus was systematically varied. Calculated parameters form recorded data - e.g., speeds of accommodation to approaching and receding targets, magnitude of accommodation to step changes in target distance, and amplitude and phase lag of response to sinusoidally varying stimuli were submitted to periodicity analyses. Ear canal temperature (ECT) and heart rate (HR) rhythms were also recorded for physiological correlation with accommodation rhythms. HR demonstrated a 24-hr rhythm, but ECT data did not.

Murphy, M. R.↗

Advancements in medicine from aerospace research

A program designed to find second applications for space technology in the medical field is described. Illustrative examples and clinical test results are included for prosthetic urethral devices, ear oximeter for monitoring leukemia patients, devices for measuring low level CO effects on automobile drivers, radiation dosimeter probe for detecting radiation levels in cancerous areas, and electromyographic muscle trainer.

Wooten, F. T.↗

Barometric pressure

The effects of alterations in barometric pressure on human beings are described. Human tolerances for gaseous environments and low and high barometric pressure are discussed, including effects on specific areas, such as the ear, lungs, teeth, and sinuses. Problems due to trapped gas within the body, high dynamic pressures on the body, and blasts are also considered.

Billings, C. E.↗

Postponement of incipient collapse due to work-induced heat stress by limited cooling

Four subjects completed five treadmill training sessions under comfortable to cool conditions and were calibrated to find an optimum combination of speed and grade on the treadmill which would produce a metabolic rate of 2000 Btu-hr. Dressed in an Apollo liquid cooling garment, each man underwent a total of four experiments in which the rate of heat extraction from the liquid cooling garment was adjusted to an amount which would cause a storage within the body of 1000 Btu/hr. Physiological measurements included skin temperature at 9 locations, rectal and ear canal probes, and heart rate. The increases in tolerance time for the various subjects and the various methods of emergency cooling, ranged from a low of six minutes to a high of 48 minutes, or from 8 to 102% of the baseline tolerance times. The largest gains were achieved in a subject whose tolerance endpoint was atypical, and whose baseline heat tolerance was unsually low.

Blockley, W. V.↗

Loudness enhancement following contralateral stimulation.

The apparent loudness of a tone pip can be increased by 15 dB or more if it is preceded by a tone burst to the contralateral ear. The experiment is done by delaying the pip, S1, by a variable time, Delta-T, after the offset of a contralateral tone; the listener assesses the loudness of S1 by adjusting the intensity of a second tone pip, S2, that follows S1 by 1500 msec. Some parametric explorations of the phenomenon are reported here.

Galambos, R.↗

Binaural signal detection - Equalization and cancellation theory.

The improvement in masked-signal detection afforded by two ears (i.e., binaural unmasking) is explained on the basis of a descriptive model of the processing of binaural stimuli by a system consisting of two bandpass filters, an equalization and cancellation mechanism, and a decision device. The main ideas of the model are initially explained, and a general equation is derived for the purpose of making quantitative predictions. Comparisons are then made between various special cases of this equation and experimental data. Failures of the preliminary model in predicting the data are considered, and possible revisions are discussed.

Durlach, N. I.↗

Environmental noise experiment (DTO 71-22)

Only general conclusions can be reached of the effect of Skylab simulation chamber noise on the crewmen. Two crewmen experienced a small hearing decrement in-chamber, but there was no pattern as to the ear and frequency affected. Temporary hearing threshold shifts were observed in all three crewmen postchamber. These postchamber threshold shifts were perhaps the most significant finding of the study. However, no lasting detrimental effects on the crew's hearing were found.

Homick, J. L.↗

Correlation of hippocampal theta rhythm with changes in cutaneous temperature

A possible role for the hippocampus in alerting an animal to changes in cutaneous temperature was examined. Following local warming or cooling of the ears of unanesthetized, loosely restrained rabbits, theta waves (4-7 Hz EEG waves) were recorded from electrodes straddling the hippocampus. The onset of the hippocampal theta rhythm was correlated with changes in cutaneous temperature, an observation consistent with studies indicating that the theta rhythm is a nonspecific response evoked by stimulation of several sensory modalities. Additional data from cats and rabbits were correlated with specific neurons within the hippocampus, namely pyramidal cells. Post stimulus time histograms obtained by excitation of the dorsal fornix were interpreted in terms of excitatory and inhibitory inputs to pyramidal cells. Thus, the theta rhythm, which appears to be evoked by changes in cutaneous temperature, can be related to a specific type of hippocampal neuron which is in turn connected with other areas of the brain involved in temperature regulation.

Horowitz, J. M.↗

Gravitational force as a determinant of turtle-shell growth and shape

Chronic low-gravity simulation (pedestal support, suspension by wires or foam, and/or clinostat tumbling) of 11 aquatic red-eared sliders, Pseudemys scripta elegans, and of nine box turtles, Terrapine carolina, resulted in continued but slower linear carapace growth. Decreased shell height was accompanied by drastic plastron infolding. Chronic centrifugation (1.4, 1.8, 2.8, 5, or 8.1 g) of 81 box turtles caused an eventual decrease (12% per g) in linear growth rate. No consistent decrease occurred with aquatic turtles centrifuged at below 6 g. Maximum growth of length and roundness appears near 5 g for aquatic environments and near 1 g in land environments. Present results suggest that some gravity is necessary for normal bone growth.

Wunder, C. C.↗

Motor activity under weightless conditions

The material presented on the motor activity under weightless conditions (brief and long) leads to the conclusion that it is not significantly disrupted, if those being examined are secured at the workplaces. Some discoordination of movement, moderately expressed disruption of the precision of reproduction of assigned muscular forces, etc., were observed. Motor disorders decrease significantly in proportion to the length of stay under weightless conditions. This apparently takes place, as a consequence of formation of a new functional system, adequate to the conditions of weightlessness. Tests on intact and labyrinthectomized animals have demonstrated that signaling from the inner ear receptors is superfluous in weightlessness, since it promotes the onset of disruptions in the combined work of the position analyzers.

Kasyan, I. I.↗

The human auditory evoked response

Figures are presented of computer-averaged auditory evoked responses (AERs) that point to the existence of a completely endogenous brain event. A series of regular clicks or tones was administered to the ear, and 'odd-balls' of different intensity or frequency respectively were included. Subjects were asked either to ignore the sounds (to read or do something else) or to attend to the stimuli. When they listened and counted the odd-balls, a P3 wave occurred at 300msec after stimulus. When the odd-balls consisted of omitted clicks or tone bursts, a similar response was observed. This could not have come from auditory nerve, but only from cortex. It is evidence of recognition, a conscious process.

Galambos, R.↗

Launch, flight, and recovery

The final phase to fly five pocket mice in the Apollo XVII command module was carried out at the NASA Kennedy Space Center. Upon completion of the 13-d space flight, the package was removed from the spacecraft and, after having been purged with an oxygen-helium gas mixture, was flown to American Samoa. Four of the five mice were recovered alive from the package. Analysis of the mouse that died during the flight revealed several factors that could have contributed to its death, the chief of which was massive hemorrhage in its middle ear cavities.

Look, B. C.↗

Weightlessness - A case history

A review of the average bodily systems functioning aboard Skylab II after 20 days of weightlessness is presented. Condition of eyes, ears, nose and throat, gastrointestinal tract, vestibular organs, cardiovascular system, musculoskeletal system, sleep, general appearance, skin, abdomen, and extremities is summarized. The general health of the crewmen is good, although there are some slight anomalies, such as weight loss, dry skin, nasal speech, and paresthesia of the soles of the feet.

Kerwin, J. P.↗