Experiment M-6, bone demineralization
Bone demineralization investigations to determine effects of weightlessness and immobilization on human skeleton
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Bone demineralization investigations to determine effects of weightlessness and immobilization on human skeleton
Periodic centrifugation effect on cardiovascular functions of man during bed rest
Physiological and psychological effects on man during U.S. suborbital and orbital flights from Project Mercury
Hypoxemia induced in man by sustained forward acceleration while breathing pure oxygen in five pounds per square inch absolute environment
Feasibility of oxygen-helium atmosphere at 380 mm Hg total pressure proven by two-week exposure of four men
Clinical nutritional study of minimum protein and caloric requirements for man
Vestibular changes, human equilibrium and orientation, and adaptation of gravitoinertial receptor mechanisms during space missions - conference
Aims and methods of program to determine effects of pure oxygen atmosphere on aviators confined for 34-days, with periods at high altitude and at sea level
Inverse relationship between retinal blood vessel caliber and oxygen level, creatinine level variations, and buildup in microorganisms during confinement of aviators in pure oxygen
Biochemical responses of humans exposed to pure oxygen environment at simulated altitude of 27,000 feet
Predicting distance at which thermal radiation from nuclear detonations will be hazardous to unprotected human eye
Sensitivity of manned planetary spacecraft design to shield weight, onboard radiation and uncertainties in space environment radiation
Weightlessness and manned space flight medical data to date
Possible decompression effects in supersonic transport cabin in terms of biomedical considerations for passenger safety
Gemini program study to provide safe and biologically sound method of man qualifying for space exploration
Three areas of research in NASA'S University Program are described. Primitive terrestrial living cells were studied as a guide to the kind of cells to look for in extraterrestrial life. Experiments in zero gravity conditions are described with emphasis upon effects on small organisms. The effects of ionizing radiation on cells are studied so that it will be possible to predict dosages which can be tolerated by humans with no permanent damage.
Two nonhuman primate species were used to investigate the effects of gravitoinertial forces on pilot incapacitation and performance impairment, to define human physiologic tolerance and safe exposure limits to these environments, and to obtain data which can be used to evolve new methods to improve man's G tolerance to match the structural capability of new generation aircraft. The macaca fascicularis was used to study the effects of environmental stress and atheroscelerosis on cerebral blood flow and function agents on myocardial and cardiovascular function were studied in the macaca mulatta.
We modeled BIO-Plex designs with separate or combined atmospheres and then simulated controlling the atmosphere composition. The BIO-Plex is the Bioregenerative Planetary Life Support Systems Test Complex, a large regenerative life support test facility under development at NASA Johnson Space Center. Although plants grow better at above-normal carbon dioxide levels, humans can tolerate even higher carbon dioxide levels. Incinerator exhaust has very high levels of carbon dioxide. An elaborate BIO-Plex design would maintain different atmospheres in the crew and plant chambers and isolate the incinerator exhaust in the airlock. This design easily controls the crew and plant carbon dioxide levels but it uses many gas processors, buffers, and controllers. If all the crew's food is grown inside BIO-Plex, all the carbon dioxide required by the plants is supplied by crew respiration and the incineration of plant and food waste. Because the oxygen mass flow must balance in a closed loop, the plants supply all the oxygen required by the crew and the incinerator. Using plants for air revitalization allows using fewer gas processors, buffers, and controllers. In the simplest design, a single combined atmosphere was used for the crew, the plant chamber, and the incinerator. All gas processors, buffers, and controllers were eliminated. The carbon dioxide levels were necessarily similar for the crew and plants. If most of the food is grown, carbon dioxide can be controlled at the desired level by scheduling incineration. An intermediate design uses one atmosphere for the crew and incinerator chambers and a second for the plant chamber. This allows different carbon dioxide levels for the crew and plants. Better control of the atmosphere is obtained by varying the incineration rate. Less gas processing storage and control is needed if more food is grown.