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Novel anatomic adaptation of cortical bone to meet increased mineral demands of reproduction
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Paramytha ossicola sp. nov. (Polychaeta, Ampharetidae) from mammal bones: Reproductive biology and population structure
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A crossover–crossback prospective study of dibutyl-phthalate exposure from mesalamine medications and serum reproductive hormones in men
Highlights: • Mesalamine medications with coatings that contain dibutyl phthalate (DBP) lead to very high DBP exposure. • New exposure to high DBP from mesalamine medications disrupted pituitary-gonadal hormones in adult men. • Among men with no or short previous high DBP exposure, the hormone disruption was reversed after exposure removal. • Long term high DBP exposure may alter the pituitary-gonadal axis and make it insensitive to removal of exposure. Phthalates, such as dibutyl phthalate (DBP), are endocrine disruptors used in some medication coatings e.g., mesalamine to treat inflammatory bowel disease (IBD).
Aloe arborescens juice prevents EMF-induced oxidative stress and thus protects from pathophysiology in the male reproductive system in vitro
Highlights: • Electromagnetic field (EMF) induces toxic events in spermatogenic cells. • Aloe juice prevents EMF-induced increased formation of reactive oxygen species. • Aloe juice inhibits ROS-mediated DNA damage, cell cycle arrest and apoptosis. • Aloe juice may preserves fertility from EMF-induced toxic events in mouse germ cells. More and more studies suggest that prolonged exposure to EMF may cause adverse biological effects and point directly to a significantly negative correlation between EMF and human health, especially men fertility. In our previous study, we reported that this could be related to the EMF-induced reactive oxygen species formation, followed by DNA damage, cell cycle arrest and apoptosis induction. In this study, we decided to expand our research by the search for substances which would prevent EMF-induced damage in spermatogenic cells. Such an agent seems to be Aloe arborescens Mill. juice, which was shown to possess a wide range of protective properties. The administration of aloe extract helps among others to prevent the formation of free radicals by various biochemical pathways. Therefore, the main aim of our study was to provide a significant knowledge concerning the mechanism involved in the multi-pathway cytoprotective response of aloe juice against EMF. The study was carried out in an in vitro mouse spermatogenesis pathway cell lines (GC-1 spg and GC-2 spd). Our results suggest that the aloe juice has many positive effects, especially for the cellular antioxidant systems by reducing the intracellular reactive oxygen species pool induced by EMF. In consequence, aloe juice prevents DNA damage, cell cycle arrest and therefore the viability and metabolic activity of both cell line tested are preserved. In conclusion, our study provides new insight into the underlying mechanisms through which aloe juice prevents spermatogenic cells from cytotoxic and genotoxic events.
Heat stress during reproductive stages reduces camelina seed productivity and changes seed composition
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Estimating the reproductive number R0 of SARS-CoV-2 in the United States and eight European countries and implications for vaccination
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Reproductive characteristics of bulls from two breed compositions and their correlations with infrared thermography
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In utero exposure to simvastatin reduces postnatal survival and permanently alters reproductive tract development in the Crl:CD(SD) male rat
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