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NASA Life Sciences Portal (NLSP): Supporting Scientific Transparency and Reproducibility

NASA’s Life Sciences Ports (NLSP) serves the scientific community by providing curated data from space life science experiment. The Human Research Program (HRP) with the help of NLSP is currently transforming their life sciences data archive systems and processes to improve compliance with the FAIR principles [1]. Some of these improvements will at the same time support the twin pillars of Open Science [2]: transparency of methods and reproducibility of results. Scientific transparency is marked by the easily intelligible communication of what has been investigated: what were the procedures for collecting sample and the characteristics of samples collected? what kinds of measurements were made, what were the environmental conditions of the measurements? What were the analysis techniques of the collected data? Reproducibility of the results and findings from the investigation requires a high level of transparency for all but the simplest investigations; the slightest deviation in communicating and replicating complex experimental procedures or data analyses can often yield quite different data and even findings, thwarting their validation. One of the ways the NLSP is aiming to improve the communication of scientific information is through the use of ontology-driven metadata. Ontologies are powerful, graph-based knowledge representation structures, which can be leveraged to increase data interoperability, the area of the FAIR principles in which many data systems most lack compliance. Over the past decade, there has been a concerted effort in the biomedical community to develop modular and narrowly focused domain and application-specific ontologies in a common, open-source framework, the Open Biological and Biomedical Ontology (OBO) Foundry [3]. The open sharing and modular nature of this effort promises huge increases in harmonized data sharing for systems that leverage these models. Which is in line with the FAIR Data Principles of Findability, Accessibility, Interoperability, and Reuse for scientific data management and stewardship. 1. Wilkinson, M.D., et al., The FAIR Guiding Principles for scientific data management and stewardship. Sci Data, 2016. 3: p. 160018. 2. National Academies of Sciences, E. and Medicine, Open Science by Design: Realizing a Vision for 21st Century Research. 2018, Washington, DC: The National Academies Press. 232. 3. Smith, B., et al., The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration. Nat Biotechnol, 2007. 25(11): p. 1251-5.

Life Sciences data↗

NASA Life Sciences Portal (NLSP): Supporting Scientific Transparency and Reproducibility

NASA’s Life Sciences Ports (NLSP) serves the scientific community by providing curated data from space life science experiment. The Human Research Program (HRP) with the help of NLSP is currently transforming their life sciences data archive systems and processes to improve compliance with the FAIR principles [1]. Some of these improvements will at the same time support the twin pillars of Open Science [2]: transparency of methods and reproducibility of results. Scientific transparency is marked by the easily intelligible communication of what has been investigated: what were the procedures for collecting sample and the characteristics of samples collected? what kinds of measurements were made, what were the environmental conditions of the measurements? What were the analysis techniques of the collected data? Reproducibility of the results and findings from the investigation requires a high level of transparency for all but the simplest investigations; the slightest deviation in communicating and replicating complex experimental procedures or data analyses can often yield quite different data and even findings, thwarting their validation. One of the ways the NLSP is aiming to improve the communication of scientific information is through the use of ontology-driven metadata. Ontologies are powerful, graph-based knowledge representation structures, which can be leveraged to increase data interoperability, the area of the FAIR principles in which many data systems most lack compliance. Over the past decade, there has been a concerted effort in the biomedical community to develop modular and narrowly focused domain and application-specific ontologies in a common, open-source framework, the Open Biological and Biomedical Ontology (OBO) Foundry [3]. The open sharing and modular nature of this effort promises huge increases in harmonized data sharing for systems that leverage these models. Which is in line with the FAIR Data Principles of Findability, Accessibility, Interoperability, and Reuse for scientific data management and stewardship.

Life Sciences data↗

Space Science for the 21st Century: The Space Science Enterprise Strategic Plan

Throughout its history, the U.S. Space Science technologies program has been enormously productive. Its accomplishments have rewritten the textbooks. But now, the economic environment has changed dramatically. The Nation's scientific and technological goals are being reexamined and redefined.And the social contract between the scientific community and the Federal Government is being rewritten. There is an expectation that the American public should receive more direct benefits from its investment in science and technology. This Strategic Plan reflects this new paradigm. It presents a carefully selected set of new scientific initiatives that build on past accomplishments to continue NASA's excellence in Space Science. At the same time, it responds to fiscal constraints by defining a new approach to planning, developing, and operating Space Science missions. In particular, investments in new technologies will permit major scientific advances to be made with smaller, more focused, and less costly missions. With the introduction of advanced technologies, smaller does not have to mean less capable. The focus on new technologies also provides and opportunity for the Space Science program to enhance its direct contribution to the country's economic base. At the same time, the program can build on public interest to strengthen its contributions to education and scientific literacy. With this plan we are taking the first steps toward shaping the Space Science program of the 21st century. In doing so, we face major challenges. It will be a very different program than might have been envisioned even a few years ago. But it will be a program that remains at the forefront of science, technology, and education. We intend to continue rewriting the textbooks.

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Highlights of Space Weather Tools and Resources at the Community Coordinated Modeling Center

In this presentation, we showcase a diverse array of tools and resources offered by the Community Coordinated Modeling Center (CCMC) to advance space weather research and support space weather services. Highlights include the Run-on-Request (RoR) and continuous run simulation services, the multi-purpose integrated Space Weather Analysis (iSWA) system (has been used for space weather monitoring, anomaly resolution, and education), space weather event database DONKI, the validation tool called CAMEL, and various scoreboard activities serving as model validation efforts before a space weather event/condition occurs (this type of pre-event validation enhances the accuracy and credibility of space weather predictions from the community). In addition, CCMC’s is an active participant providing strong support for NASA’s Heliophysics Big Year activities. Above all, our team welcomes collaborations in the broad range of áreas. Through this presentation, we aim to inspire engagement and collaboration among latinoamerican scientific communities and CCMC.

Yihua Zheng↗

Destination Mars: An Astronaut's Perspective

The recent discovery of possible fossilized life forms within a Martian meteorite has rekindled interest in human exploration of the planet. While the global scientific community must carefully study this physical evidence as well as await the results of 4 space probes to Mars in the coming years, others are looking ahead to the next logical step of sending humans to the planet. Such a feat, while a tremendous scientific undertaking, is nearly within the grasp of current technology. The travel distance involved and the harsh Martian environment itself impose great challenges to human physiology as well as to spacecraft design. Mission planners face challenges from the long-duration microgravity environment, complex life-support systems, interplanetary radiation, and the psychological stressors involved in such an endeavor.

Parazynski, Scott↗

The Evolving Universe: Structure and Evolution of the Universe Roadmap 2000-2020

The Roadmap for the Structure and Evolution of the Universe (SEU) theme embraces three fundamental, scientific quests: (1) To explain structure in the Universe and forecast our cosmic destiny. (2) To explore the cycles of matter and energy in the evolving Universe. (3) To examine the ultimate limits of gravity and energy in the Universe. These quests are developed into six, focused research campaigns addressing the objectives of one or more quests: Identify dark matter and learn how it shapes galaxies and systems of galaxies; Find out where and when the chemical elements were made; Understand the cycles in which matter, energy, and magnetic field are exchanged between stars and the gas between stars; Discover how gas flows in disks and how cosmic jets are formed; Identify the sources of gamma-ray bursts and high-energy cosmic rays; and Measure how strong gravity operates near black holes and how it affects the early Universe. These campaigns lead to a portfolio of future major missions of strong scientific and popular appeal, strongly endorsed by the scientific community and which has undergone significant initial study. Some of these missions are in a state of readiness that makes ideal candidates for the present Office of Space Science Strategic Plan; others may well feature in the next Strategic Plan. Each provides a golden scientific opportunity to advance our understanding of the Universe. Our highest priority science objectives are addressed by five Observatory Class Missions, unranked by science, but in approximate order of readiness: A high-energy gamma-ray facility that will observe relativistic jets and study the sources of cosmic gamma ray bursts; An ultra-sensitive X-ray telescope, optimized for spectroscopy, to examine the hot gas linked with clusters of galaxies, the disks around black holes, and supernova explosions; A large, radio telescope in deep space to map central regions of distant quasars and perform astrometric investigations; An orbiting gravitational coalescing, massive black holes and test how gravity waves distort spacetime; A pair of Earth-orbiting, optical telescopes that will detect flashes of light produced when ultra high-energy cosmic rays impact the upper atmosphere so as to determine their arrival directions and energies. A new program for supporting pertinent international collaboration is strongly endorsed and maintaining a strong Explorer program is important. The flexibility to exploit exceptional opportunities, such as attaching payloads to space station, should also be acquired. A strong technology development program must be initiated now to enable this mission set.

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Lossless compression of image data products on th e FIFE CD-ROM series

How do you store enough of the key data sets, from a total of 120 gigabytes of data collected for a scientific experiment, on a collection of CD-ROM's, small enough to distribute to a broad scientific community? In such an application where information loss in unacceptable, lossless compression algorithms are the only choice. Although lossy compression algorithms can provide an order of magnitude improvement in compression ratios over lossless algorithms the information that is lost is often part of the key scientific precision of the data. Therefore, lossless compression algorithms are and will continue to be extremely important in minimizing archiving storage requirements and distribution of large earth and space (ESS) data sets while preserving the essential scientific precision of the data.

Newcomer, Jeffrey A.↗

Alternate physical formats for storing data in HDF

Since its inception HDF has evolved to meet new demands by the scientific community to support new kinds of data and data structures, larger data sets, and larger numbers of data sets. The first generation of HDF supported simple objects and simple storage schemes. These objects were used to build more complex objects such as raster images and scientific data sets. The second generation of HDF provided alternate methods of storing data elements, making it possible to do such things as store extendible objects with in HDF, to store data externally from HDF files, and support data compression effectively. As we look to the next generation of HDF, we are considering fundamental changes to HDF, including a redefinition of the basic HDF object from a simple object to a more general, higher-level scientific data object that has certain characteristics, such as dimensionality, a more general atomic number type, and attributes. These changes suggest corresponding changes to the HDF file format itself.

Folk, Mike↗

Global Cooperation in the Science of Sun-Earth Connection

The international space science community had recognized the importance of space weather more than a decade ago, which resulted in a number of international collaborative activities such as the International Space Weather Initiative (ISWI), the Climate and Weather of the Sun Earth System (CAWSES) by SCOSTEP and the International Living with a Star (ILWS) program. These programs have brought scientists together to tackle the scientific issues related to short and long term variability of the Sun and the consequences in the heliosphere. The ISWI program is a continuation of the successful International Heliophysical Year (IHY) 2007 program in focusing on science, observatory deployment, and outreach. The IHY/ISWI observatory deployment has not only filled voids in data coverage, but also inducted young scientists from developing countries into the scientific community. The ISWI schools and UN workshops are the primary venues for interaction and information exchange among scientists from developing and developed countries that lead to collaborative efforts in space weather. This paper presents a summary of ISWI activities that promote space weather science via complementary approaches in international scientific collaborations, capacity building, and public outreach.

Gopalswamy, Natchimuthuk↗

Aerothermodynamic environment for a Titan probe with deployable decelerator

It is pointed out that further exploration of Titan, Saturn's largest moon, is of current interest to the scientific community, particularly from the standpoint of the organic chemical evolution of its atmosphere. For a suitable study of this Saturnian satellite, a mission involving a Titan atmospheric entry probe is to be conducted. The probe is to employ a deployable decelerator with the aim to allow scientific measurements in the haze layer. The present investigation is concerned with an assessment of the aerothermodynamic environment for the considered probe during its hypervelocity, low-Reynolds-number entry. Attention is given to the employed computational method, the Titan probe configuration, the Titan probe trajectory, the viscous-layer regime of the aerothermodynamic environment, and the incipient merged-layer regime.

Green, M. J.↗

SIMBIOS Project 1998 Annual Report

The purpose of this series of technical reports is to provide current documentation of the Sensor Intercomparison and Merger for Biological and Interdisciplinary Ocean Studies (SIMBIOS) Project activities, NASA Research Announcement (NRA) research status, satellite data processing, data product validation and field calibration. This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report is not meant to substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issues by an operational project.

McClain, Charles R.↗

Heat Capacity Mapping Mission (HCMM) Notification Efforts

To encourage wide use of the Heat Capacity Mapping Mission (HCMM) data, especially among the scientific community, special notifications were prepared to inform them about the data's availability, its form, and the procedures for obtaining them. To achieve the widest distribution to the primary audiences of interest, mailings were made to scientists associated with the OSTA Resource Observation Division programs and to scientific and professional societies and journals. Accompanying the notifications to the societies and journals were samples of the HCMM imagery and a description of the image's predominant characteristics. A follow-up survey was completed to determine the effectiveness of the HCMM notifications.

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The future scientific CCD

Since the first introduction of charge-coupled devices (CCDs) in 1970, CCDs have been considered for applications related to memories, logic circuits, and the detection of visible radiation. It is pointed out, however, that the mass market orientation of CCD development has left largely untapped the enormous potential of these devices for advanced scientific instrumentation. The present paper has, therefore, the objective to introduce the CCD characteristics to the scientific community, taking into account prospects for further improvement. Attention is given to evaluation criteria, a summary of current CCDs, CCD performance characteristics, absolute calibration tools, quantum efficiency, aspects of charge collection, charge transfer efficiency, read noise, and predictions regarding the characteristics of the next generation of silicon scientific CCD imagers.

Janesick, J. R.↗

SIMBIOS Project 1999 Annual Report

The purpose of this technical memorandum is to provide current documentation of the Sensor Intercomparison and Merger for Biological and Interdisciplinary Oceanic Studies (SIMBIOS) Project activities, NASA Research Announcement (NRA) research status, satellite data processing, data product validation, and field calibration. This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report is not meant as a substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issued by an operational project.

McClain, Charles R.↗

Proceedings of the 8th Precise Time and Time Interval (PTTI) Applications and Planning Meeting

The Proceedings contain the papers presented at the Eight Annual Precise Time and Tme Interval PTTI Applications and Planning Meeting. The edited record of the discussions following the papers and the panel discussions are also included. This meeting provided a forum for the exchange of information on precise time and frequency technology among members of the scientific community and persons with program applications. The 282 registered attendees came from various U.S. Government agencies, private industry, universities and a number of foreign countries were represented. In this meeting, papers were presented that emphasized: (1) definitions and international regulations of precise time sources and users, (2) the scientific foundations of Hydrogen Maser standards, the current developments in this field and the application experience, and (3) how to measure the stability performance properties of precise standards. As in the previous meetings, update and new papers were presented on system applications with past, present and future requirements identified.

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Trajectory options for the Comet Rendezvous Asteroid Flyby mission

The Comet Rendezvous Asteroid Flyby mission is strongly supported by the scientific community. Two major events during the past year have forced a re-analysis of the mission options, with the goal of selecting a baseline mission for launch in 1993. Venus and earth gravity assists can be used to allow rendezvous with comet Tempel 2 in 1996; the scientific potential of the resulting mission is excellent. Although backup mission opportunities have been identified, the significantly longer flight times weaken the scientific appeal of these missions.

Miller, S. L.↗

The Acquisition, Containment, and Curation of Mars Samples on Earth

The Astromaterials Acquisition and Curation Office at NASA Johnson Space Center (henceforth AACO) is responsible for receiving and curating all of NASA’s extraterrestrial samples, current and future (as per NASA Policy Directive (NPD) 7100.10E “Curation of Extraterrestrial Materials”). As such, the AACO coordinates sample capture, containment, and transportation to the curation facility as well as documents, preserves, prepares, and distributes all of the samples within NASA’s astromaterial collections for research, education, and public outreach. Since the lunar rock and soil samples returned during the Apollo Program, NASA’s first Class V Restricted Earth Return Missions, the AACO curates six other astromaterials collections. Lessons learned from each collection and respective missions (e.g. Apollo, Genesis, Stardust) as well as advancements in science and technology have informed the AACO’s plan for acquiring and curating Martian samples. Given the nature of the collection, a mobile and modular facility is recommended. The two broad requirements a Mars sample facility must maintain are: 1) the ability to contain the samples to protect the public from exposure of an “unknown unknown” biological agent and 2) ensure the scientific integrity of the samples are maintained (while maximizing scientific outcome). Although Apollo samples were eventually deemed safe and released to the scientific community for evaluation, there is no guarantee that this will be the case for Martian samples. Therefore, the facility in which the samples will be contained and investigated must be modular and able to accommodate an array of instrumentation that could be highly variable depending on the initial scientific outcomes. Furthermore, in order to facilitate proper sample capture and containment upon landing as well as sample distribution to other laboratories with proper containment, a mobile facility is a valuable investment.

Harrington, Andrea D.↗

In Situ Aerosol Optical Thickness Collected by the SIMBIOS Program (1997-2000): Protocols, and and Data QC and Analysis

The purpose of this technical report is to provide current documentation of the Sensor Intercomparison and Merger for Biological and Interdisciplinary Oceanic Studies (SIMBIOS) Project Office activities on in situ aerosol optical thickness (i.e., protocols, and data QC and analysis). This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of validating and combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report is not meant as a substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issued by an operational project.

Fargion, Giulietta S.↗