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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 145 records · Page 8
All sourcesNASA NTRSDOE OSTI
NASA NTRS1971

Inhaled ozone as a mutagen. II - Effect on the frequency of chromosome aberrations observed in irradiated Chinese hamsters.

Exposure-adjusted break frequencies for chromosome aberrations produced in Chinese hamster circulating blood lymphocytes were the quantitative indicator of damage from 5 hrs of exposure to X-radiation and/or to ozone. Radiation produced 5.51 x 0.0001 breaks/cell rad for cells withdrawn 2 weeks after exposure, a reasonable value when compared with data from in vivo exposure of human lymphocytes and Chinese hamster bone marrow cells. Animals exposed to the two agents simultaneously exhibited more than 70% of the total breaks anticipated assuming the expected equal contributions to be additive. Extending to humans, at presently permitted levels, exposure to ozone would be much more detrimental than exposure to radiati*n.

Zelac, R. E.↗
NASA NTRS1975

Holographic gratings for spectrographic applications: Study of aberrations

The design and fabrication of holographic gratings requires an understanding of Fermat's principle. This principle states that the path of a light ray from one point to another is that which requires the least time. The aberrant, optical path of an object point to an image was studied using Fermat principles.

Bhatia, M. S.↗
NASA NTRS1983

Beam Splitter Introduces Little Aberration

Placing beam splitter inside existing lens minimizes aberrations. Six channel beam splitter has optical paths of lengths equal to distances traveled by rays. Lens element cemented to each of exit faces of beam splitter is optically concentric with element cemented to entrance face and with center of curvature of monocentric optical system. Beam splitter makes it possible to form separate image in each wavelength channel of interest.

Evans, N. L., Jr.↗
NASA NTRS1986

Analytical aberration model for an infrared telescope

An analytical model for an infrared telescope is described. The model gives not only the prescription and the third-order aberrations but also the influence of tilts and decenters of the secondary ont he first- and third-order properties of the system as a function of the input parameters. Predictions obtained with this model are compared with the results of real ray tracing.

Shack, Roland V.↗
NASA NTRS1991

Aberration corrected aspheric grating for far ultraviolet spectrographs - Conventional approach

Two approaches to reducing optical aberrations of concave grating spectrographs have been used, holographically controlling the groove curvature and spacing and reshaping the optical substrate while ruling the grooves conventionally. The latter approach, slightly deforming an ellipsoidal grating blank, can lead to diffraction-limited performance at a single FUV wavelength. When such a grating is used in a slitted Rowland circle spectrograph, the result is an extremely efficient spectrograph with spectral resolving power of about 30,000 and low astigmatism. Optical fabrication technology has advanced to the point where these exotic surface gratings are becoming practical.

Content, David↗
NASA NTRS1992

Aberration-corrected aspheric grating designs for the Lyman/Far-Ultraviolet Spectroscopic Explorer high-resolution spectrograph - A comparison

Two approaches to reducing the optical aberrations of concave diffraction gratings have been studied to obtain candidate grating designs for the Lyman/Far-Ultraviolet Spectroscopic Explorer mission. The first approach involves shaping the grating substrate while using straight and equally spaced grooves. The second approach involves using a gating substrate with a relatively simple figure and holographically controlling the groove curvature and spacing. Specific designs derived from both approaches are analyzed and compared.

Trout, Catherine↗
NASA NTRS1999

Aberrations in Fresnel Lenses and Mirrors

The NASA/MSFC Shooting Star program revealed a number of technical problems that must be solved before solar thermal propulsion can become a reality. The fundamental problem of interest here is the collection of solar energy. This is the first step in the propulsion process and indeed the most important. Everything else depends on the efficiency and focusing ability of the collection lens or mirror. An initial model of Fresnel lens behavior using a wave optics approach has been completed and the results were encouraging enough to warrant an experimental investigation. This experimental investigation confirmed some of the effects predicted and produced invaluable photographic evidence of coherence based diffraction and aberration.

Gregory, Don↗
NASA NTRS2006

A Novel Concept for a Deformable Membrane Mirror for Correction of Large Amplitude Aberrations

Very large, light weight mirrors are being developed for applications in space. Due to launch mass and volume restrictions these mirrors will need to be much more flexible than traditional optics. The use of primary mirrors with these characteristics will lead to requirements for adaptive optics capable of correcting wave front errors with large amplitude relatively low spatial frequency aberrations. The use of low modulus membrane mirrors actuated with electrostatic attraction forces is a potential solution for this application. Several different electrostatic membrane mirrors are now available commercially. However, as the dynamic range requirement of the adaptive mirror is increased the separation distance between the membrane and the electrodes must increase to accommodate the required face sheet deformations. The actuation force applied to the mirror decreases inversely proportional to the square of the separation distance; thus for large dynamic ranges the voltage requirement can rapidly increase into the high voltage regime. Experimentation with mirrors operating in the KV range has shown that at the higher voltages a serious problem with electrostatic field cross coupling between actuators can occur. Voltage changes on individual actuators affect the voltage of other actuators making the system very difficult to control. A novel solution has been proposed that combines high voltage electrodes with mechanical actuation to overcome this problem. In this design an array of electrodes are mounted to a backing structure via light weight large dynamic range flextensional actuators. With this design the control input becomes the separation distance between the electrode and the mirror. The voltage on each of the actuators is set to a uniform relatively high voltage, thus the problem of cross talk between actuators is avoided and the favorable distributed load characteristic of electrostatic actuation is retained. Initial testing and modeling of this concept demonstrates that this is an attractive concept for increasing the dynamic range capability of electrostatic deformable mirrors.

Moore, Jim↗
NASA NTRS2007

Chromosome Aberrations in Astronauts

A review of currently available data on in vivo induced chromosome damage in the blood lymphocytes of astronauts proves that, after protracted exposure of a few months or more to space radiation, cytogenetic biodosimetry analyses of blood collected within a week or two of return from space provides a reliable estimate of equivalent radiation dose and risk. Recent studies indicate that biodosimetry estimates from single spaceflights lie within the range expected from physical dosimetry and biophysical models, but very large uncertainties are associated with single individual measurements and the total sample population remains low. Retrospective doses may be more difficult to estimate because of the fairly rapid time-dependent loss of "stable" aberrations in blood lymphocytes. Also, biodosimetry estimates from individuals who participate in multiple missions, or very long (interplanetary) missions, may be complicated by an adaptive response to space radiation and/or changes in lymphocyte survival and repopulation. A discussion of published data is presented and specific issues related to space radiation biodosimetry protocols are discussed.

George, Kerry A.↗
NASA NTRS2007

Painting Analysis of Chromosome Aberrations Induced by Energetic Heavy Ions in Human Cells

This viewgraph presentation reviews some of the techniques used to analyze the damage done to chromosome from ion radiation. Fluorescence in situ hybridization (FISH), mFISH, mBAND, telomere and centromereprobes have been used to study chromosome aberrations induced in human cells exposed to low-and high-LET radiation in vitro. There is some comparison of the different results from the various techniques. The results of the study are summarized.

Wu, Honglu↗
NASA NTRS2007

Analysis of Chromosomal Aberrations in the Blood Lymphocytes of Astronauts after Space Flight

It is a NASA requirement that biodosimetry analysis be performed on all US astronauts who participate in long duration missions of 3 months or more onboard the International Space Station. Cytogenetic analysis of blood lymphocytes is the most sensitive and reliable biodosimetry method available at present, especially if chromosome damage is assessed before as well as after space flight. Results provide a direct measurement of space radiation damage in vivo that takes into account individual radiosensitivity and considers the influence of microgravity and other stress conditions. We present data obtained from all twenty-five of the crewmembers who have participated in the biodosimetry program so far. The yield of chromosome exchanges, measured using fluorescence in situ hybridization (FISH) technique with chromosome painting probes, increased after space flight for all these individuals. In vivo dose was derived from frequencies of chromosome exchanges using preflight calibration curves of in vitro exposed cells from the same individual, and RBE was compared with individually measured physically absorbed dose and projected organ dose equivalents. Biodosimetry estimates using samples collected within a few weeks of return from space lie within the range expected from physical dosimetry. For some of these individuals chromosome aberrations were assessed again several months after their respective missions and a temporal decline in stable exchanges was observed in some cases, suggesting that translocations are unstable with time after whole body exposure to space radiation. This may indicate complications with the use of translocations for retrospective dose reconstruction. Data from one crewmember who has participated in two separate long duration space missions and has been followed up for over 10 years provides limited data on the effect of repeat flights and shows a possible adaptive response to space radiation exposure.

George, K.↗
NASA NTRS2007

Biomarker for Space Radiation Risk: Painting Analysis of Chromosome Aberrations Induced by Energetic Heavy Ions in Human Cells

Energetic heavy ions pose a great health risk to astronauts in extended ISS and future Lunar and Mars missions. High-LET heavy ions are particularly effective in causing various biological effects, including cell inactivation, genetic mutations, cataracts and cancer induction. Most of these biological endpoints are closely related to chromosomal damage, which can be utilized as a biomarker for radiation insults. Over the years, we have studied chromosomal damage in human fibroblast, epithelia and lymphocyte cells exposed in vitro to energetic charged particles generated at several accelerator facilities in the world. We have also studied chromosome aberrations in astronaut s peripheral blood lymphocytes before and after space flight. Various fluorescence in situ hybridization painting techniques have been used to identify from only the telomere region of the chromosome to every chromosome in a human cell. We will summarize the results of the investigations, and discuss the unique radiation signatures and biomarkers for space radiation exposure.

Hada, Megumi↗
NASA NTRS2005

Telescope Wavefront Aberration Compensation with a Deformable Mirror in an Adaptive Optics System

With the goal of reducing the surface wavefront error of low-cost multi-meter-diameter mirrors from about 10 waves peak-to-valley (P-V), at lpm wavelength, to approximately 1-wave or less, we describe a method to compensate for slowly varying wavefront aberrations of telescope mirrors. A deformable mirror is utilized in an active optical compensation system. The kMS wavefront error of a 0.3m telescope improved to 0.05 waves (0.26 waves P-V) from the original value of 1.4 waves RMS (6.5 waves P-V), measured at 633nm, and the Strehl ratio improved to 89% from the original value of 0.08%.

active optics↗
NASA NTRS2009

Hybrid diversity method utilizing adaptive diversity function for recovering unknown aberrations in an optical system

A method of recovering unknown aberrations in an optical system includes collecting intensity data produced by the optical system, generating an initial estimate of a phase of the optical system, iteratively performing a phase retrieval on the intensity data to generate a phase estimate using an initial diversity function corresponding to the intensity data, generating a phase map from the phase retrieval phase estimate, decomposing the phase map to generate a decomposition vector, generating an updated diversity function by combining the initial diversity function with the decomposition vector, generating an updated estimate of the phase of the optical system by removing the initial diversity function from the phase map. The method may further include repeating the process beginning with iteratively performing a phase retrieval on the intensity data using the updated estimate of the phase of the optical system in place of the initial estimate of the phase of the optical system, and using the updated diversity function in place of the initial diversity function, until a predetermined convergence is achieved.

Dean, Bruce H.↗