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A Year in Space: Early Results and Lessons Learned from the First Year-Long Expedition Aboard the International Space Station

Two ISS crewmembers recently completed the first year-long orbital stay in two decades. International cooperation was central to the success of Mikhail Kornienko from Russia and Scott Kelly from the United States. Their expedition leveraged current mission experience and capitalized on recent advances in health monitoring technology. This unique effort began in 2012 when the program managers of the ISS partner nations adopted two separate goals: greater multilateral cooperation to increase efficiency of inflight research and a year-long expedition to gain familiarity with in-flight durations approaching that required for a Mars mission. These goals were unified when a set of bilateral Russian and American human research investigations was assigned to the year-long mission, augmented by additional investigations from Europe and Japan. For example, Kelly was assigned 18 investigations (twice the complement on standard six-month missions) including two joint U.S.-Russian studies, and two Russian and two Japanese studies. The core set of American investigations was a repetition of six studies Kelly had done on his previous six-month ISS mission, to allow a direct comparison of physiological and behavioral responses of the longer and shorter durations in this single individual. The remainder of his assignments plus those of Kornienko were drawn from currently active national investigations documenting human adaptation to long-duration spaceflight factors or effectiveness of countermeasures against known deleterious adaptations. The two joint U.S.-Russian investigations were the flagship biomedical studies of the year-long expedition. The "Fluid Shifts" study collocated American research equipment alongside a Russian operational stressor device to document the pattern and impacts of the headward fluid shift long known to occur in weightlessness, including its role in ocular changes recently observed in some astronauts. The "Field Test" study investigated the ability of the astronaut and cosmonaut to perform rudimentary tasks requiring sensorimotor coordination immediately after landing to define human capabilities soon after landing on Mars after an extended transit. Both investigations were highly successful in large part to the thorough integration of the implementation processes of the two partners. Kelly's assignment as the one-year crewmember also provided a serendipitous opportunity for the "Twins Study" comparing changes in his body at the genetic level with those occurring on Earth in his identical twin brother Mark Kelly. Data analysis from this expedition will commence in earnest after frozen in-flight samples are delivered to Earth in May aboard a commercial cargo spacecraft. Detailed results are expected in early 2017. Preliminary results and implementation improvements will be reviewed in this presentation.

Charles, J. B.↗

Quantitative Comparison of Proprietary and Open-Source Georeferencing Tools for Use with Astronaut Photography

The Crew Earth Observations (CEO) Facility within the Earth Science and Remote Sensing Unit at NASA’s Johnson Space Center supports the acquisition, analysis, and curation of astronaut photography of Earth’s surface and atmosphere. Astronauts on the International Space Station (ISS) respond to requests from CEO to acquire imagery of scientific and education targets, to include high profile targets in response to activations from the International Charter for Space & Major Disasters (also known as the International Disaster Charter, or IDC) and NASA’s Disasters Program. CEO facilitates the acquisition of astronaut photography in response to IDC events and delivers georeferenced data products to the United States Geological Survey (USGS) for distribution to the disaster community. Using GeoRef, an internal web-based tool developed in collaboration with NASA’s Ames Research Center, CEO generates data packages of georeferenced imagery, uncertainty images for assessing control and tie point accuracy, and metadata documenting raw and processed data. Operational experience with the Georef software identified vulnerabilities to internal code and server errors that can significantly increase time of data production. As such, CEO developed a backup procedure in case the GeoRef software experiences front-end or back-end errors. A system using OSGEO’s open-source QGIS software combined with a semi-automated pipeline using the object-oriented Python language and the Geospatial Abstract Library for generating metadata is quantitatively compared to GeoRef’s data package for quality and productivity. Root Mean Square Error (RMSE) provides a standard measurement of data quality as it relates to ground error. Assessing RMSE measurements generated from georeferenced astronaut photographs acquired with different obliquity and focal length offers a comprehensive accuracy assessment of the software’s transformation algorithms. This assessment will indicate the software's ability to produce data products with the least ground-error or highest data quality regarding ground accuracy. In addition, a comparison of the software’s efficiency in generating a data package that includes georeferenced images, metadata, and uncertainty images for measuring tie/ground point error was performed. Initial results, based on the comparison of three nadir-facing astronaut photographs acquired with a 95mm focal length, reveal the QGIS-based system's average RMSE is 2.36 (pixels) suggesting its georectification system produces data products that meet and perhaps improve upon Georef solution's average RMSE of 32.99 (pixels). However, the QGIS system was unable to reproduce two unique Georef data products, uncertainty images for measuring tie and control point errors and a translated unwrapped image. In addition, the Georef software is designed to accept handheld camera pose information from a hardware component (Geosens) scheduled for deployment on the ISS in late 2018; this information is intended to provide increased accuracy and auto-registration capability for astronaut photographs. Future work is expected to determine the QGIS-based georectification system’s potential as an open-source alternative (and operational backup) to Georef for georeferencing the full range of resolutions and viewing angles unique to handheld digital camera imagery in support of ISS disaster response activities.

Jagge, Amy M.↗

Disruption of postural readaptation by inertial stimuli following space flight

Postural instability (relative to pre-flight) has been observed in all shuttle astronauts studied upon return from orbital missions. Postural stability was more closely examined in four shuttle astronaut subjects before and after an 8 day orbital mission. Results of the pre- and post-flight postural stability studies were compared with a larger (n = 34) study of astronauts returning from shuttle missions of similar duration. Results from both studies indicated that inadequate vestibular feedback was the most significant sensory deficit contributing to the postural instability observed post flight. For two of the four IML-1 astronauts, post-flight postural instability and rate of recovery toward their earth-normal performance matched the performance of the larger sample. However, post-flight postural control in one returning astronaut was substantially below mean performance. This individual, who was within normal limits with respect to postural control before the mission, indicated that recovery to pre-flight postural stability was also interrupted by a post-flight pitch plane rotation test. A similar, though less extreme departure from the mean recovery trajectory was present in another astronaut following the same post-flight rotation test. The pitch plane rotation stimuli included otolith stimuli in the form of both transient tangential and constant centripetal linear acceleration components. We inferred from these findings that adaptation on orbit and re-adaptation on earth involved a change in sensorimotor integration of vestibular signals most likely from the otolith organs.

NASA Center JSC↗

A Dynamic Fountain Model for Lunar Dust

During the Apollo era of exploration it was discovered that sunlight was scattered at the terminators giving rise to horizon glow and streamers above the lunar surface. This was observed from the dark side of the Moon during sunset and sunrise by both surface landers and astronauts in orbit. These observations were quite unexpected, as the Moon was thought to be a pristine environment with a negligible atmosphere or exosphere. Subsequent investigations have shown that the sunlight was most likely scattered by electrostatically charged dust grains originating from the surface. It has since been demonstrated that this dust population could have serious implications for astronomical observations from the lunar surface. The lunar surface is electrostatically charged by the Moon s large-scale interaction with the local plasma environment and the photoemission of electrons due to solar ultra-violet (UV) light and X-rays. The like-charged surface and dust grains then act to repel each other, such that under certain conditions the dust grains are lifted above the surface. We present a dynamic fountain model which can explain how sub-micron dust is able to reach altitudes of up to approximately 100 km above the lunar surface. Previous static dust levitation models are most applicable to the heavier micron-sized grains in close proximity proximity to the surface, but they cannot explain the presence of extremely light grains at high altitudes. If we relax the static constraint applied to previous models, and instead assume that the grains are in constant motion (under the action of dynamic forces), a new picture emerges for the behavior of sub-micron lunar dust.

Stubbs, T. J.↗

Earth Science Engagement Through Art and Astronaut Photography

For over five decades of manned spaceflight missions, NASA astronauts have taken extraordinary photographs of Earth's surface and dynamic processes. Humans on board the International Space Station (ISS) have a unique platform to perform Earth observations at various viewing angles, seasons, and times of day. Astronaut photos taken from the ISS comprise a true‐color (RGB) dataset taken with multiple handheld digital cameras and lens types (prior to 2004, film cameras were in use). Earth observations through astronaut photography are an important and unique remote sensing method when monitoring natural disasters, urban growth, and environmental changes. While astronaut imagery can be used for earth science research, there is also an artistic aspect to the photography that fascinates a wide global population. A broader public audience can be introduced to earth science through high resolution, Earth art photos taken from the perspective of an astronaut. The Crew Earth Observations (CEO) Facility within the Earth Science and Remote Sensing Unit at NASA's Johnson Space Center supports the acquisition, analysis, and curation of astronaut photography of Earth's surface and atmosphere. CEO's website, the Gateway to Astronaut Photography of Earth (eol.jsc.nasa.gov), provides free public access to view, search, and download over three million images taken by astronauts throughout all of NASA's crewed spaceflight history, with an emphasis on current ISS imagery. The CEO Facility actively curates a digital collection of exceptional Earth art astronaut photos used for public engagement. Our new Downloadable Earth Art page focuses on broad earth science topics including: mountains, water, clouds, agriculture, as well as an "abstract" category. This continuously‐updated collection is comprised of freely accessible and high‐quality downloadable materials, such as single‐ and dual‐screen digital wallpapers. All Earth Art materials are presented with science‐based information that complements the artistic qualities of the imagery, and facilitate connections between general audiences and earth science from the International Space Station.

Meado, Andrea L.↗

Earth observations during Space Shuttle mission STS-34 - 18-23 October 1989

An overview is presented of the 31st Space Shuttle mission, whose major objective was to deploy the Galileo spacecraft. Color images are presented of photos taken by the four videocameras in the payload bay, one 16-mm Arriflex in the cabin, a videocamcorder, three 35 mm cameras, two 70 mm cameras, and an IMAX camera. In addition, descriptions of visual observations by the mission astronauts are given. The most significant STS-34 earth photography for the major geographical regions is discussed. Individual highlights of this mission include observation of the apparent recovery of the water level of Lake Nasser to conditions similar to those during the second Space Shuttle mission of 1981; the documentation of the impact of the Yucatan forest blowdown and fires after the passage of Hurricane Gilbert; and the confirmation of the high value of space photography under low and very low sun angle conditions for geomorphological and geological analyses.

Helfert, Michael R.↗

Head Tilt Posturography to Enhance Balance Control Assessment for Astronauts: A Case Study

For many years, we have used a standard clinical computerized dynamic posturography (CDP) protocol to assess recovery of integrated sensory-motor function in astronauts returning from space flight. The most reliable indications of postflight crew performance capabilities have been obtained from the sensory organization tests (SOTs) within the CDP protocol, particularly SOTs 5 (eyes closed, surface support sway referenced) and 6 (eyes open, surface support and visual surround sway referenced), which are sensitive to changes in availability and/or utilization of vestibular cues. We have observed, however, that some astronauts exhibiting visible signs of incomplete sensory-motor recovery are able to score within clinical norms on standard SOTs 5 and 6 trials, perhaps as a result of cognitive strategies driven by their naturally competitive natures. To improve the sensitivity of the CDP protocol for assessing recovery of integrated sensory-motor function and fitness to return to duties and/or activities of daily living, we have introduced pitch plane head tilt SOT trials to our protocol. In a preliminary study of 5 short duration (~11day missions) astronauts, we showed that they were unable to maintain balance on landing day when performing dynamic head tilt trials, despite scoring within the clinically normal range on the standard SOT trials. The present case report illustrates the advantages of including head tilt trials for assessing sensory-motor recovery in long duration crewmembers.

Hwang, E. Y.↗

The Crew Earth Observations Experiment: Earth System Science from the ISS

This viewgraph presentation reviews the use of Astronaut Photography (AP) as taken from the International Space Station (ISS) in Earth System Science (ESS). Included are slides showing basic remote sensing theory, data characteristics of astronaut photography, astronaut training and operations, crew Earth observations group, targeting sites and acquisition, cataloging and database, analysis and applications for ESS, image analysis of particular interest urban areas, megafans, deltas, coral reefs. There are examples of the photographs and the analysis.

Stefanov, William L.↗

Midodrine as a Countermeasure to Orthostatic Hypotension Immediately After Space Shuttle Landing

Midodrine prevents post-space flight orthostatic intolerance when testing is conducted in a controlled laboratory setting within 2-4 hours after Space Shuttle landing. It is unknown if midodrine is as effective during re-entry and immediately following landing. METHODS: Cardiovascular responses to 10 minutes of 80 head-up tilt in five male astronauts were compared before and immediately after Space Shuttle missions. Preflight tests were conducted in the Johnson Space Center Cardiovascular Laboratory without midodrine. Post-flight testing was performed in the Crew Transport Vehicle on the Space Shuttle runway within 60 minutes of landing; midodrine was self-administered before re-entry. Survival analysis was performed (Gehan-Breslow test) to compare presyncope rates pre- to post-flight. Cardiovascular responses (last minute standing minus supine) to tilt before and after space flight were compared using paired t-tests. RESULTS: Midodrine did not prevent post-flight orthostatic hypotension in two of the five astronauts, but the rate of presyncope across the group did not increase (p=0.17) from pre- to post-flight. Also, although the change in heart rate from supine to the last minute of standing was not affected by space flight, systolic blood pressure decreased more (p=0.05) and diastolic blood pressure tended to decrease (p=0.08) after space flight. CONCLUSIONS: Accurate interpretation of the current results requires that similar data be collected in control subjects (without midodrine) on the CTV. However, drug interaction concerns with commonly used anti-emetics and potentiation of prolonged QTc intervals observed in long duration astronauts make the routine use of midodrine for immediate post-flight orthostatic hypotension unlikely. 2

Platts, Steven H.↗

Global geologic applications of the Space Shuttle earth observations photography database

The advantages of the astronaut photography during Space Shuttle missions are briefly examined, and the scope and applications of the Space Shuttle earth observations photography database are discussed. The global and multidisciplinary nature of the data base is illustrated by several examples of geologic applications. These include the eruption of Mount Pinatubo (Philippine Islands), heat flow and ice cover on Lake Baikal in Siberia (Russia), and windblown dust in South America. It is noted that hand-held photography from the U.S. Space Shuttle provides unique remotely-sensed data for geologic applications because of the combination of varying perspectives, look angles, and illumination, and changing resolution resulting from different lenses and altitudes.

Lulla, Kamlesh↗

An evaluation of training effectiveness of an intelligent tutoring system

The study evaluated the training effectiveness of an intelligent tutoring system (ITS) for the Remote Manipulator System (RMS). The study examined how well individuals learn the training content and skills from the RMS ITS and to what extent the content and skills learned using the ITS transfer to RMS task performance in the SES, a high fidelity simulator. Three astronauts completed 8 2-hour ITS sessions addressing movement in three coordinate systems, grapple, ungrapple, berth, and unberth procedures, and singularities and reach limits. Their performance was also observed in an SES training session. Performance data were collected using multiple measures: ITS task performance, transfer performance on the SES, a conceptual knowledge test, an opinion survey completed by astronauts, and comments and observations from astronauts and trainers. Results indicated the RMS ITS to be moderately effective and provided evidence of the efficacy of ITS's, in general. Comments and suggestions are provided relating to how the ITS could be improved and to enable decision makers to judge the effectiveness of the RMS ITS.

Johnson, Debra Steele↗

Suppression of antigen-specific lymphocyte activation in modeled microgravity

Various parameters of immune suppression are observed in lymphocytes from astronauts during and after a space flight. It is difficult to ascribe this suppression to microgravity effects on immune cells in crew specimens, due to the complex physiological response to space flight and the resultant effect on in vitro immune performance. Use of isolated immune cells in true and modeled microgravity in immune performance tests, suggests a direct effect of microgravity on in vitro cellular function. Specifically, polyclonal activation of T-cells is severely suppressed in true and modeled microgravity. These recent findings suggest a potential suppression of oligoclonal antigen-specific lymphocyte activation in microgravity. We utilized rotating wall vessel (RWV) bioreactors as an analog of microgravity for cell cultures to analyze three models of antigen-specific activation. A mixed-lymphocyte reaction, as a model for a primary immune response, a tetanus toxoid response and a Borrelia burgdorferi response, as models of a secondary immune response, were all suppressed in the RWV bioreactor. Our findings confirm that the suppression of activation observed with polyclonal models also encompasses oligoclonal antigen-specific activation.

NASA Discipline Cell Biology↗

Field Evaluation in Four NEEMO Divers of a Prototype In-suit Doppler Ultrasound Bubble Detector

It is desirable to know if astronauts produce venous gas emboli (VGE) as a result of their exposure to 4.3 psia during space walks. The current prototype in-suit Doppler (ISD) ultrasound bubble detector provides an objective assessment of decompression stress by monitoring for VGE. The NOAA Aquarius habitat and NASA Extreme Environment Mission Operations (NEEMO) series of dives provided an opportunity to assess the ability of the prototype ISDs to record venous blood flow and possibly detect VGE in the pulmonary artery. From July 16 to 29,2003, four aquanauts (two males and two females) donned the ISD for a 4 hr automated recording session, following excursion dives (up to 6hrs and 29 MSW below storage depth) from air saturation at 17 MSW. Doppler recordings for 32 excursion dives were collected. The recordings consisted of approximately 150 digital wave files. Each wave file contained 24 sec of recording for each min. A 1 - 4 Doppler Quality Score (DQS) was assigned to each wave file in 17 of the 32 records evaluated to date. A DQS of 1 indicates a poor flow signal and a score of 4 indicates an optimum signal. Only 23% of all wave files had DQSs considered adequate to detect low grade VGE (Spencer I-II). The distribution of DQS in 2,356 wave files is as follows: DQS 1-56%, DQS 2-21%, DQS 3-18% and DQS 4-5%. Six of the 17 records had false positive VGE (Spencer I-IV) detected in one or more wave files per dive record. The false positive VGE recordings are attributable to air entrainment associated with drinking (verified by control tests), and this observation is important as astronauts drink water during space walks. The current ISD design provides quality recordings only over a narrow range of chest anatomy.

Acock, K. E.↗

Skylab Apollo Telescope Mount Calibration Rocket Project

The Calibration Rocket (CALROC) Project was established to provide calibration data for the Harvard College Observatory (S055) and the Naval Research Laboratory (S082) ultraviolet solar experiments on Skylab to provide compensation for any change in performance during the long mission in the space environment after the preflight calibration. The calibration instruments were smaller-scale, lighter-weight, but similar in performance to the S055 and S082 experiments. They were launched on Black Brant VC sounding rockets from White Sands Missile Range, New Mexico. The CALROC instruments were calibrated before launch and verified after flight. Each flight obtained approximately four minutes of data on an area of the sun which was then observed by the Skylab astronauts with the ATM experiments on three successive orbits.

Frank, M. W.↗

Smoke detection in low-G fires

Fires in spacecraft are considered a credible risk. To respond to this risk, NASA flew fire detectors on Skylab and the Space Shuttle (STS) and included them in the design for International Space Station Alpha (ISSA). In previous missions (Mercury, Gemini and Apollo), the crew quarters were so cramped that it was not considered credible that the astronauts could fail to observe a fire. The Skylab nodule included approximately 20 UV fire detectors. The space shuttle has 9 ionization detectors in the mid deck and flight deck and Spacelab has six additional ionization detectors. The planned detectors for ISSA are laser-diode, forward-scattering, smoke or particulate detectors. Current plans for the ISSA call for two detectors in the open area of the module and detectors in racks that have both cooling air flow and electrical power. Due to the complete absence of data concerning the nature of particulate and radiant emission from low-g fires, all three of these detector systems were designed based upon 1-g test data. As planned mission durations and complexity increase and the volume of spacecraft increases, the need for and importance of effective, crew independent, fire detection grows significantly. This requires more knowledge concerning low-gravity fires and how they might be detected. To date, no combustion-generated particulate samples have been collected for well-developed microgravity flames. All of the extant data come from drop tower tests and therefore only correspond to the early stages of a fire. The fuel sources were restricted to laminar gas-jet diffusion flames and rapidly overheated wire insulation. These gas-jet drop tower tests indicate, through thermophoretic sampling, that soot primaries and aggregates (groups of primary particles) in micro-g may be significantly larger than those in normal-g (ng). This raises new scientific questions about soot processes as well as practical issues for particulate detection/alarm threshold levels used in on-orbit smoke detectors. Furthermore, it is widely speculated but unverified that the aggregates will grow to very large scales in a microgravity fire of longer duration than available on the ground. Preliminary tests in the 2.2 second drop tower suggest that particulate generated by overheated wire insulation will also be larger in microgravity than in normal gravity. TEM grids downstream of the fire region in the WIF experiment as well as visual observation of long string-like aggregates, further confirm this suggestion. The combined impact of these limited results and theoretical predictions is that direct knowledge of low-g combustion particulate as opposed to extrapolation from 1-g data is needed for a more confident design of smoke detectors for spacecraft.

Urban, David L.↗