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At least 145 records · Page 8

Recent Developments in Security-Constrained AC Optimal Power Flow: Overview of Challenge 1 in the ARPA-E Grid Optimization Competition

In “Recent Developments in Security-Constrained AC Optimal Power Flow: Overview of Challenge 1 in the ARPA-E Grid Optimization Competition,” we review the state of the art in practical algorithms for scheduling power-systems operations in the short term and the results of the recent competition organized by the U.S. Advanced Research Projects Agency–Energy. We explain the mixed-integer nonlinear formulation used in the competition for nonspecialists in electrical engineering, the context and organization of the competition, and the performance of competitors. We find that the collective approaches and results of competitors provide support for efforts to move nonlinear optimization techniques into industrial applications, as they have proven to be a robust and efficient alternative to current linear approximation techniques.

24 POWER TRANSMISSION AND DISTRIBUTION↗

ARPA-E Grid Optimization (GO) Competition Challenge 2

The ARPA-E Grid Optimization (GO) Competition Challenge 2, from 2020 to 2021, expanded upon the problem posed in Challenge 1 by adding adjustable transformer tap ratios, phase shifting transformers, switchable shunts, price-responsive demand, ramp rate constrained generators and loads, and fast-start unit commitment. Furthermore, Challenge 2 was a maximization problem while Challenge 1 was a minimization problem. Specifically, the economic surplus, defined as the benefit of serving load minus the cost of generation, is being maximized. It was expected that the objective value of a given solution should be positive, representing economic gain, but negative objectives from poor solutions were possible. The two code submission feature of Challenge 1 was maintained. Additionally, Divisions 3 and 4 within the competition permitted on/off switching of transmission lines (Divisions 1 and 2 did not). After the initial release of the Problem Formulation on 7/20/2020, ARPA-E Director Lane Genatowski announced Challenge 2 on 9/12/2020. The final May 31, 2021, version of the Problem Formulation was 97 pages long with 299 equations. The Challenge proceeded with 2 non-prize Events and 2 prize Events. Teams receiving Challenge 1 FOA awards and prize money were required to use the prize money to fund their Challenge 2 efforts (Georgia Institute of Technology, Global Optimal Technology, Inc., Lawrence Livermore National Laboratory, Lehigh University, Northwestern University, Artelys, Columbia, Pearl Street Technologies, Pennsylvania State University, and University of Colorado Boulder). For more information on the competition and challenge 2 see the "GO Competition Challenge 2 Information" resource below. Challenge 1 and Challenge 3 information can be found in the resources linked below.

ACOPF↗

Laboratory earthquake forecasting: A machine learning competition

Earthquake prediction, the long-sought holy grail of earthquake science, continues to confound Earth scientists. Could we make advances by crowdsourcing, drawing from the vast knowledge and creativity of the machine learning (ML) community? We used Google’s ML competition platform, Kaggle, to engage the worldwide ML community with a competition to develop and improve data analysis approaches on a forecasting problem that uses laboratory earthquake data. The competitors were tasked with predicting the time remaining before the next earthquake of successive laboratory quake events, based on only a small portion of the laboratory seismic data. The more than 4,500 participating teams created and shared more than 400 computer programs in openly accessible notebooks. Complementing the now well-known features of seismic data that map to fault criticality in the laboratory, the winning teams employed unexpected strategies based on rescaling failure times as a fraction of the seismic cycle and comparing input distribution of training and testing data. In addition to yielding scientific insights into fault processes in the laboratory and their relation with the evolution of the statistical properties of the associated seismic data, the competition serves as a pedagogical tool for teaching ML in geophysics. The approach may provide a model for other competitions in geosciences or other domains of study to help engage the ML community on problems of significance.

58 GEOSCIENCES↗

Mycorrhizal nutrient acquisition strategies shape tree competition and coexistence dynamics

Mycorrhizal fungi with different nutrient acquisition strategies influence plant species performance and physiology, thereby defining their trophic niche. This might drive resource competition dynamics that cumulatively impact tree species coexistence, but few manipulative experiments have directly tested this. Combining surveys and experiments in a modern coexistence theory framework, we tested how variation in mycorrhizal strategies and nutrient conditions affects plant competitive outcomes. We focused on two genera of co-occurring tree species with different mycorrhizal states: Acer (arbuscular mycorrhizal, AM) and Populus (dual mycorrhizal, but often considered predominantly ectomycorrhizal, EM). The EM and AM fungal responsiveness in Populus species varied with latitude and nitrogen (N) limitation. Host-specific soil microbiome conditioning and inorganic N fertilization combined to qualitatively affect coexistence outcomes. Lower N conditions favoured Populus over Acer trees, and N fertilization reversed this outcome for southern species, aligning with regional-scale forest mycorrhizal transitions. Results from the coexistence experiment also predict competitive exclusion between the tree species pairs, which could arise, in part, from their mycorrhizal differences and is consistent with alternative stable states in dominant forest mycorrhizal strategies. Such bistability appears in natural systems as a bimodal distribution of Populus vs. Acer tree species dominance using long-term forest inventory data. Synthesis: The magnitude and outcome of microbially mediated competition between Populus and Acer depends on soil nutrient availability, which likely relates to their mycorrhizal differentiation. These findings support the importance of mycorrhizal symbioses for contributing to large-scale biogeographical patterns of tree species trophic niche separation across soil resource gradients and bistability in forest mycorrhizal structure.

54 ENVIRONMENTAL SCIENCES↗

Competitive Exclusion and Metabolic Dependency among Microorganisms Structure the Cellulose Economy of an Agricultural Soil

Microorganisms that degrade cellulose utilize extracellular reactions that yield free by-products which can promote interactions with noncellulolytic organisms. We hypothesized that these interactions determine the ecological and physiological traits governing the fate of cellulosic carbon (C) in soil. We performed comparative genomics with genome bins from a shotgun metagenomic-stable isotope probing experiment to characterize the attributes of cellulolytic and noncellulolytic taxa accessing 13 C from cellulose. We hypothesized that cellulolytic taxa would exhibit competitive traits that limit access, while noncellulolytic taxa would display greater metabolic dependency, such as signatures of adaptive gene loss. We tested our hypotheses by evaluating genomic traits indicative of competitive exclusion or metabolic dependency, such as antibiotic production, growth rate, surface attachment, biomass degrading potential, and auxotrophy. The most 13 C-enriched taxa were cellulolytic Cellvibrio (Gammaproteobacteria) and Chaetomium (Ascomycota), which exhibited a strategy of self-sufficiency (prototrophy), rapid growth, and competitive exclusion via antibiotic production. Auxotrophy was more prevalent in cellulolytic Actinobacteria than in cellulolytic Proteobacteria, demonstrating differences in dependency among cellulose degraders. Noncellulolytic taxa that accessed 13 C from cellulose (Planctomycetales, Verrucomicrobia, and Vampirovibrionales) were also more dependent, as indicated by patterns of auxotrophy and 13 C labeling (i.e., partial labeling or labeling at later stages). Major 13 C-labeled cellulolytic microbes (e.g., Sorangium, Actinomycetales, Rhizobiales, and Caulobacteraceae) possessed adaptations for surface colonization (e.g., gliding motility, hyphae, attachment structures) signifying the importance of surface ecology in decomposing particulate organic matter. Our results demonstrated that access to cellulosic C was accompanied by ecological trade-offs characterized by differing degrees of metabolic dependency and competitive exclusion.

59 BASIC BIOLOGICAL SCIENCES↗

Business Plan Competitions and Technology Transfer

Business plan competitions are used in many industries to stimulate interactions between startup companies and potential investors, inducing investment in those companies and fueling technology transfer into the marketplace. However, no empirical studies have tested the effectiveness of these competitions at helping companies raise funding and become a successful business entity. We use a difference-in-differences model to estimate the effect of participation in the National Renewable Energy Laboratory’s (NREL) Industry Growth Forum (IGF), a clean technology business plan competition. We find that companies that present at the IGF on average raise $\$$4.4M (p<0.01) more than those that applied and were not selected to present. We find no significant effect from company location and proximity to investors, which suggests that the business clusters’ effect on a company’s success may be limited. Presenting companies exhibit increased investment syndication compared to the rest of the clean technology industry; for example, an IGF presenter with $\$$9M in funding may have twice the number of investors as typical clean technology startups that raised the same amount of funding but did not present at the IGF. These findings suggest that business competitions can help nascent companies raise financing and help venture capitalists find investment opportunities, and may serve as an effective policy tool to facilitate the growth of clean technology companies, industries, and technology transfer.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

U.S. Department of Energy Collegiate Wind Competition 2024: Rules - Phase 2 and 3

The U.S. Department of Energy (DOE) Wind Energy Technologies Office's (WETO) Collegiate Wind Competition (CWC, also referred to as the "Competition" in this rules document) invites interdisciplinary teams of undergraduate students from a variety of academic programs to solve complex wind energy challenges. Through the competition, WETO intends to offer students direct industry experience, valuable exposure to wind energy career pathways, and greater knowledge of wind energy's potential to contribute to a clean energy future. The competition will select up to 35 teams to start, making them eligible to compete for a cash prize pool of up to $280,000.

Collegiate Wind Competition↗

The Effect of Salts in Promoting Specific and Competitive Interactions between Zinc Finger Proteins and Metals

Specific protein–metal interactions (PMIs) fulfill essential functions in cells and organic bodies, and activation of these functions in vivo are mostly modulated by the complex environmental factors, including pH value, small biomolecules, and salts. Specifically, the role of salts in promoting specific PMIs and their competition among various metals has remained untapped mainly due to the difficulty to distinguish nonspecific PMIs from specific PMIs by classic spectroscopic techniques. Herein, we report Hofmeister salts differentially promote the specific PMIs by combining nanoelectrospray ionization mass spectrometry and spectroscopic techniques (fluorescence measurement and circular dichroism). Furthermore, to explore the influence of salts in competitive binding between metalloproteins and various metals, we designed a series of competitive experiments and applied to a well-defined model system, the competitive binding of zinc (II) and arsenic (III) to holo-promyelocytic leukemia protein (PML). These experiments not only provided new insights at the molecular scale as complementary to previous NMR and spectroscopic results, but also deduced the relative binding ability between zinc finger proteins and metals at the molecular scale, which avoids the mass spectrometric titration-based determination of binding constants that is frequently affected and often degraded by variable solution conditions including salt contents. .

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

SNHG16 contributes to breast cancer cell migration by competitively binding miR-98 with E2F5

Long noncoding RNAs (lncRNAs) have been proved to play important roles in cellular processes of cancer, including the development, proliferation, and migration of cancer cells. In the present study, we demonstrated small nucleolar RNA host gene 16 (SNHG16) as an oncogene on cell migration in breast cancer. Expression levels of SNHG16 were found to be frequently higher in breast cancer tissues than in the paired noncancerous tissues. Gain- and loss-of-function studies proved that SNHG16 significantly promoted breast cancer cell migration. We predicted SNHG16 as a competitive endogenous RNA (ceRNA) of E2F transcription factor 5 protein (E2F5) via competition for the shared miR-98 through bioinformatics analysis, and proved this regulation using relative quantitative real-time PCR (qRT-PCR), western blot, RNA immunoprecipitation (RIP) assay and luciferase reporter assay. In addition, we identified a positive correlation between SNHG16 and E2F5 in breast cancer tissues. Furthermore, we demonstrated that forced expression of miR-98 could partially abrogate SNHG16-mediated increase of breast cancer cells migration, suggesting that SNHG16 promoted cell migration in a miR-98 dependent manner. Taken together, our findings indicated that SNHG16 induces breast cancer cell migration by competitively binding miR-98 with E2F5, and SNHG16 can serve as a potential therapeutic target for breast cancer treatment. - Highlights: • SNHG16 was first shown to work as a ceRNA by competitively binding miR-98 with E2F5. • SNHG16 promotes breast cancer cell migration in a miR98-dependent manner. • Direct combination of SNHG16 with miR-98 was proved using RIP and luciferase assay. • The positive regulation of E2F5 by SNHG16 in breast cancer was revealed.

60 APPLIED LIFE SCIENCES↗

On the competitive antagonism effect in combined chloride-sulfate attack: A numerical exploration

Highlights: • A chemo-physical-mechanical method based on thermodynamic modelling is implemented. • The contradicting findings from reported experiments are numerically explored. • The competitive antagonism effect is time-dependent rather than a conclusive term. • The competitive antagonism effect is quantifiable with a novel assessment criterion. It is of tremendous difficulty to draw a conclusive verdict on the complex process of mutual interference regarding the combined chloride-sulfate attack on concrete, where many have explored the topic, but contradicting results have been reported. In this paper, by taking advantages of the chemo-physical-mechanical method, based on the robust technique of thermodynamic modelling, the competitive antagonism effect in combined chloride-sulfate attack is investigated. Firstly, a range of reported tests are numerically modelled to demonstrate the effectiveness of the employed method in interpreting those opposing and diverse experimental outcomes. More importantly, a fresh conjecture incorporating a novel assessment criterion for the competitive antagonism effect is proposed and supported through a carefully designed illustrative example. Based on the numerical exploration, unique findings and implications for future engineering practices are revealed.

36 MATERIALS SCIENCE↗

Environmentally persistent free radical-containing particulate matter competitively inhibits metabolism by cytochrome P450 1A2

Combustion processes generate different types of particulate matter (PM) that can have deleterious effects on the pulmonary and cardiovascular systems. Environmentally persistent free radicals (EPFRs) represent a type of particulate matter that is generated after combustion of environmental wastes in the presence of redox-active metals and aromatic hydrocarbons. Cytochromes P450 (P450/CYP) are membrane-bound enzymes that are essential for the phase I metabolism of most lipophilic xenobiotics. The EPFR formed by chemisorption of 2-monochlorophenol to silica containing 5% copper oxide (MCP230) has been shown to generally inhibit the activities of different forms of P450s without affecting those of cytochrome P450 reductase and heme oxygenase-1. The mechanism of inhibition of rat liver microsomal CYP2D2 and purified rabbit CYP2B4 by MCP230 has been shown previously to be noncompetitive with respect to substrate. In this study, MCP230 was shown to competitively inhibit metabolism of 7-benzyl-4-trifluoromethylcoumarin and 7-ethoxyresorufin by the purified, reconstituted rabbit CYP1A2. MCP230 is at least 5- and 50-fold more potent as an inhibitor of CYP1A2 than silica containing 5% copper oxide and silica, respectively. Thus, even though PM generally inhibit multiple forms of P450, PM interacts differently with the forms of P450 resulting in different mechanisms of inhibition. P450s function as oligomeric complexes within the membrane. We also determined the mechanism by which PM inhibited metabolism by the mixed CYP1A2–CYP2B4 complex and found that the mechanism was purely competitive suggesting that the CYP2B4 is dramatically inhibited when bound to CYP1A2. - Highlights: • Combustion of organic pollutants generates long-lived particulate radicals (EPFRs). • Particulate matter (PM) competitively inhibited CYP1A2 activity. • EPFRs were much more potent CYP1A2 inhibitors than other types of PM. • PM interacts differently with different forms of P450. • PM competitively inhibited metabolism by the mixed CYP1A2–CYP2B4 complex.

60 APPLIED LIFE SCIENCES↗

Harmonic mode competition in a terahertz gyrotron backward-wave oscillator

Electron cyclotron maser interactions at terahertz (THz) frequencies require a high-order-mode structure to reduce the wall loss to a tolerable level. To generate THz radiation, it is also essential to employ cyclotron harmonic resonances to reduce the required magnetic field strength to a value within the capability of the superconducting magnets. However, much weaker harmonic interactions in a high-order-mode structure lead to serious mode competition problems. The current paper addresses harmonic mode competition in the gyrotron backward wave oscillator (gyro-BWO). We begin with a comparative study of the mode formation and oscillation thresholds in the gyro-BWO and gyromonotron. Differences in linear features result in far fewer 'windows' for harmonic operation of the gyro-BWO. Nonlinear consequences of these differences are examined in particle simulations of the multimode competition processes in the gyro-BWO, which shed light on the competition criteria between modes of different as well as the same cyclotron harmonic numbers. The viability of a harmonic gyro-BWO is assessed on the basis of the results obtained.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Robustness of cluster synchronous patterns in small-world networks with inter-cluster co-competition balance

All edges in the classical Watts and Strogatz's small-world network model are unweighted and cooperative (positive). By introducing competitive (negative) inter-cluster edges and assigning edge weights to mimic more realistic networks, this paper develops a modified model which possesses co-competitive weighted couplings and cluster structures while maintaining the common small-world network properties of small average shortest path lengths and large clustering coefficients. Based on theoretical analysis, it is proved that the new model with inter-cluster co-competition balance has an important dynamical property of robust cluster synchronous pattern formation. More precisely, clusters will neither merge nor split regardless of adding or deleting nodes and edges, under the condition of inter-cluster co-competition balance. Numerical simulations demonstrate the robustness of the model against the increase of the coupling strength and several topological variations.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Mode competition and selection in overmoded surface wave oscillator

The overmoded surface wave oscillator (SWO) is one of the promising devices to generate high-power millimeter and subterahertz waves for its merits of high efficiency and easy fabrication. But the employed slow wave structure with large diameter may introduce mode competition as the adverse effects. Therefore, the mode competition and selection in the overmoded surface wave oscillator are investigated in detail in this paper. By using the theoretical analysis and particle-in-cell simulation, the potential transverse mode and axial mode competition is pointed out, and the physical mechanisms and methods for mode selection are investigated. At last, the results are verified in the design of a 0.14 THz overmoded SWO without mode competition, which can generate the output power up to 70 MW at the frequency of 146.3 GHz with conversion efficiency almost 20% when beam voltage and current are, respectively, about 313 kV and 1.13 kA.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Timing of mutualist arrival has a greater effect on Pinus muricata seedling growth than interspecific competition

Interactions with symbiotic microbes, such as mycorrhizal fungi, have the potential to greatly influence plant growth, but it is unclear whether field variation in symbiont availability is common and, if so, sufficient to influence interspecific plant competition. In a greenhouse experiment using natural field soils, I varied the timing of ectomycorrhizal inoculation and the presence of an arbuscular mycorrhizal plant competitor, and measured their effects on pine seedling growth. I found that ectomycorrhizal colonization was absent in some field soils, and that in soils without mycorrhizal inoculum, delayed arrival of ectomycorrhizal spores progressively reduced pine seedling growth and favoured growth of the competitor. Competition had significant negative effects on pine seedling growth, but the competition effect was much smaller than the effect of delayed mutualist arrival. Synthesis. The importance of mycorrhizal spore arrival time on pine growth suggests that plants may experience mutualist limitation more frequently than previously expected, and the relative magnitude of seedling responses to mycorrhizal fungi and competing plants show that in some systems mutualism is likely of equal or greater importance compared with interspecific competition in affecting plant community assembly.

59 BASIC BIOLOGICAL SCIENCES↗

Boulder damage symposium annual thin film laser damage competition

Optical instruments and laser systems are often fluence-limited by multilayer thin films deposited on the optical surfaces. When comparing publications within the laser damage literature, there can be confusing and conflicting laser damage results. This is due to differences in testing protocols between research groups studying very different applications. In this series of competitions, samples from multiple vendors are compared under identical testing parameters and a single testing service. Unlike a typical study where a hypothesis is tested within a well-controlled experiment with isolated variables, this competition isolates the laser damage testing variables so that trends can be observed between different deposition processes, coating materials, cleaning techniques, and multiple coating suppliers. The resulting series of damage competitions has also been designed to observe general trends of damage morphologies and mechanisms over a wide range of coating types (high reflector and antireflector), wavelengths (193 to 1064 nm), and pulse lengths (180 fs to 13 ns). A double blind test assured sample and submitter anonymity were used in each of the competitions so only a summary of the deposition process, coating materials, layer count and spectral results are presented. Laser resistance was strongly affected by substrate cleaning, coating deposition method, and coating material selection whereas layer count and spectral properties had minimal impact.

42 ENGINEERING↗

Bioactive exometabolites drive maintenance competition in simple bacterial communities

During prolonged resource limitation, bacterial cells can persist in metabolically active states of non-growth. These maintenance periods, such as those experienced in stationary phase, can include upregulation of secondary metabolism and release of exometabolites into the local environment. As resource limitation is common in many environmental microbial habitats, we hypothesized that neighboring bacterial populations employ exometabolites to compete or cooperate during maintenance and that these exometabolite-facilitated interactions can drive community outcomes. Here, we evaluated the consequences of exometabolite interactions over the stationary phase among three environmental strains: Burkholderia thailandensis E264, Chromobacterium subtsugae ATCC 31532, and Pseudomonas syringae pv. tomato DC3000. We assembled them into synthetic communities that only permitted chemical interactions. We compared the responses (transcripts) and outputs (exometabolites) of each member with and without neighbors. We found that transcriptional dynamics were changed with different neighbors and that some of these changes were coordinated between members. The dominant competitor B. thailandensis consistently upregulated biosynthetic gene clusters to produce bioactive exometabolites for both exploitative and interference competition. These results demonstrate that competition strategies during maintenance can contribute to community-level outcomes. It also suggests that the traditional concept of defining competitiveness by growth outcomes may be narrow and that maintenance competition could be an additional or alternative measure.

59 BASIC BIOLOGICAL SCIENCES↗

Grid Optimization (GO) Competition Platform

A software for a multi-challenge power-flow grid optimization competition was developed. The platform brings together high performance computing clusters, webservers, databases, competition datasets, schedulers, evaluation codes, and a multitude of language compilers and optimization solvers to host the competition. The original video announcing the competition, from former Secretary Perry, at: https://www.youtube.com/watch?v=hZwX3P9vS8M

Veeramany, Arun↗