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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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All sourcesNASA NTRSDOE OSTI
DOE OSTI2024

Evaluating county-level lung cancer incidence from environmental radiation exposure, PM 2.5 , and other exposures with regression and machine learning models

Characterizing the interplay between exposures shaping the human exposome is vital for uncovering the etiology of complex diseases. For example, cancer risk is modified by a range of multifactorial external environmental exposures. Environmental, socioeconomic, and lifestyle factors all shape lung cancer risk. However, epidemiological studies of radon aimed at identifying populations at high risk for lung cancer often fail to consider multiple exposures simultaneously. For example, moderating factors, such as PM 2.5 , may affect the transport of radon progeny to lung tissue. This ecological analysis leveraged a population-level dataset from the National Cancer Institute’s Surveillance, Epidemiology, and End-Results data (2013–17) to simultaneously investigate the effect of multiple sources of low-dose radiation (gross γ activity and indoor radon) and PM 2.5 on lung cancer incidence rates in the USA. County-level factors (environmental, sociodemographic, lifestyle) were controlled for, and Poisson regression and random forest models were used to assess the association between radon exposure and lung and bronchus cancer incidence rates. Tree-based machine learning (ML) method perform better than traditional regression: Poisson regression: 6.29/7.13 (mean absolute percentage error, MAPE), 12.70/12.77 (root mean square error, RMSE); Poisson random forest regression: 1.22/1.16 (MAPE), 8.01/8.15 (RMSE). The effect of PM 2.5 increased with the concentration of environmental radon, thereby confirming findings from previous studies that investigated the possible synergistic effect of radon and PM 2.5 on health outcomes. In summary, the results demonstrated (1) a need to consider multiple environmental exposures when assessing radon exposure’s association with lung cancer risk, thereby highlighting (1) the importance of an exposomics framework and (2) that employing ML models may capture the complex interplay between environmental exposures and health, as in the case of indoor radon exposure and lung cancer incidence.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗
NASA NTRS1992

The emulsion chamber technology experiment

Photographic emulsion has the unique property of recording tracks of ionizing particles with a spatial precision of 1 micron, while also being capable of deployment over detector areas of square meters or 10's of square meters. Detectors are passive, their cost to fly in Space is a fraction of that of instruments of similar collecting. A major problem in their continued use has been the labor intensiveness of data retrieval by traditional microscope methods. Two factors changing the acceptability of emulsion technology in space are the astronomical costs of flying large electronic instruments such as ionization calorimeters in Space, and the power and low cost of computers, a small revolution in the laboratory microscope data-taking. Our group at UAH made measurements of the high energy composition and spectra of cosmic rays. The Marshall group has also specialized in space radiation dosimetry. Ionization calorimeters, using alternating layers of lead and photographic emulsion, to measure particle energies up to 10(exp 15) eV were developed. Ten balloon flights were performed with them. No such calorimeters have ever flown in orbit. In the ECT program, a small emulsion chamber was developed and will be flown on the Shuttle mission OAST-2 to resolve the principal technological questions concerning space exposures. These include assessments of: (1) pre-flight and orbital exposure to background radiation, including both self-shielding and secondary particle generation; the practical limit to exposure time in space can then be determined; (2) dynamics of stack to optimize design for launch and weightlessness; and (3) thermal and vacuum constraints on emulsion performance. All these effects are cumulative and affect our ability to perform scientific measurements but cannot be adequately predicted by available methods.

Gregory, John C.↗
DOE OSTI2024

Advancing process-based flood frequency analysis for assessing flood hazard and population flood exposure

Recent studies have showcased the use of process-based hydrological models with Stochastic Storm Transposition (SST) techniques to conduct Flood Frequency Analysis (FFA). This framework, referred hereby FFA-SST, has proved to be a robust strategy to estimate peak flows of specific annual exceedance probability (e.g., 100-year peak flow) that can reflect natural and anthropogenic disturbances, including changes in land use and meteorological patterns. With the objective of advancing the FFA-SST framework, this study presents for the first time the use of an Integrated Surface-Subsurface Hydrological Model (ISSHM) to conduct FFA-SST by extending the analysis from peak flow responses to flood extent, enabling a unique view and analysis of flood hazard and population flood exposure at the basin scale. As a proof-of-concept, we used the ISSHM, Advanced Terrestrial Simulator (Amanzi-ATS) model, and the SST model, RainyDay, to conduct FFA-SST by simulating the flood response to 5,000 annual synthetic storm events in a 2,227 $km^2$ Southeast Texas watershed. We demonstrate that ATS, without site-specific calibration, provides a robust process-based representation of peak flows, flood extent, streamflow, evapotranspiration, soil moisture content, and water storage changes. Our results and analyses, covering frequency curves up to a 500-year return period for peak flows, basin inundation fractions, and the number of people exposed to flooding, offer a unique perspective to analyze flood impacts across spatial scales. Overall, this study provides critical insights for flood risk management by extending the FFA-SST framework to include both flood hazard and population flood exposure analyses at the basin scale. Such an approach will empower stakeholders and disaster emergency agencies with a more comprehensive understanding of flood impacts across the entire basin domain, facilitating informed decision-making for flood risk assessment and management.

58 GEOSCIENCES↗
NASA NTRSDate not supplied

Characterization of Radiation Exposure at Aviation Flight Altitudes Using the Nowcast of Aerospace Ionizing Radiation System (NAIRAS)

Exposure to ionizing radiation from galactic cosmic rays (GCRs) and solar energetic particles (SEPs) at aircraft flight altitudes can have an adverse effect on human health. Although airline crews are classified as radiation workers by the International Commission on Radiological Protection (ICRP), in most countries, their level of exposure is unquantified and undocumented throughout the duration of their career. As such, there is a need to assess pilot ionizing radiation exposure. The Nowcast of Aerospace Ionizing Radiation System (NAIRAS), a real-time global, physics-based model is used to assess such exposure. The Automated Radiation Measurements for Aerospace Safety (ARMAS) measurement dataset consists of high latitude, high altitude, and long-duration aircraft flights between 2013-2021. Here, we characterize radiation exposure at aviation flight altitudes using the NAIRAS model and compare with over 800 flight trajectories from the ARMAS flight measurement inventory.

Daniel B Phoenix↗
NASA NTRSDate not supplied

Characterization of Radiation Exposure at Aviation Flight Altitudes Using the Nowcast of Aerospace Ionizing Radiation System (NAIRAS)

Exposure to ionizing radiation from galactic cosmic rays (GCR) and solar energetic particles (SEP) at aircraft flight altitudes can have an adverse effect on human health. Although airline crews are classified as radiation workers by the International Commission on Radiological Protection (ICRP), in most countries, their level of exposure is unquantified and undocumented throughout the duration of their career. As such, there is a need to assess pilot ionizing radiation exposure. The Nowcast of Aerospace Ionizing Radiation System (NAIRAS), a real-time, global, physics-based model is used to assess such exposure. The Automated Radiation Measurements for Aerospace Safety (ARMAS) measurement dataset consists of high latitude, high altitude, and long-duration aircraft flights between 2013-2023. Here, we characterize radiation exposure at aviation flight altitudes using the NAIRAS model and compare with over 1000 flight trajectories from the ARMAS flight measurement inventory.

Daniel B Phoenix↗
DOE OSTI2026

Considerations and Mitigations for Liquid Metal Target Campaigns in the Material Plasma Exposure eXperiment

This document reports a detailed initial risk assessment associated with the exposure of liquid metal (LM) targets to plasma flux in the Material Plasma Exposure eXperiment (MPEX) at ORNL. This document, while preliminary, does give a comprehensive mitigation plan to the risks along with justification and recommendations before potentially proceeding to LM exposures. At the date of issuance of this report, the MPEX Project has completed Final Design, and the MPEX device is in the Fabrication stage. Remaining project stages include Commissioning of the device with plasma and transitioning to routine Operations for research. As will be described in this document, since the MPEX device is currently being fabricated and the existing design does not include sufficient engineering provisions for most LM targets, no LM exposures will be conducted in MPEX until further assessment can be conducted and the necessary engineering changes incorporated (during MPEX Operations.)

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2023

Natural gas odorants: A scoping review of health effects

Organosulfur compounds are intentionally added to natural gas as malodorants with the intent of short-term nasal inhalation to aid in leak detection. Regulatory exposure limits have not been established for all commonly used natural gas odorants, and recent community-level exposure events and growing evidence of indoor natural gas leakage have raised concerns associated with natural gas odorant exposures. We conducted a scoping review of peer-reviewed scientific publications on human exposures and animal toxicological studies of natural gas odorants to assess toxicological profiles, exposure potential, health effects and regulatory guidelines associated with commonly used natural gas odorants. We identified only 22 studies which met inclusion criteria for full review. Overall, there is limited evidence of both transient nonspecific health symptoms and clinically diagnosed causative neurotoxic effects associated with prolonged odorant exposures. Across seven community-level exposure events and two occupational case reports, consistent symptom patterns included: headache, ocular irritation, nose and throat irritation, respiratory complaints such as shortness of breath and asthma attacks, and skin irritation and rash. Of these, respiratory inflammation and asthma exacerbations are the most debilitating, whereas the high prevalence of ocular and dermatologic symptoms suggest a non-inhalation route of exposure. The limited evidence available raises the possibility that organosulfur odorants may pose health risks at exposures much lower than presently understood, though additional dose-response studies are needed to disentangle specific toxicologic effects from nonspecific responses to noxious organosulfur odors. Numerous recommendations are provided including more transparent and prescriptive natural gas odorant use practices.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗
NASA NTRS2013

RF Exposure Analysis for Multiple Wi-Fi Devices In Enclosed Environment

Wi-Fi devices operated inside a metallic enclosure have been investigation in the recent years. A motivation for this study is to investigate wave propagation inside an enclosed environment such as elevator, car, aircraft, and spacecraft. There are performances and safety concerned that when the RF transmitters are used in the metallic enclosed environments. In this paper, the field distributions inside a confined room were investigated with multiple portable Wi-Fi devices. Computer simulations were performed using the rigorous computational electromagnetics (CEM). The method of moments (MoM) was used to model the mutual coupling among antennas. The geometrical theory of diffraction (GTD) was applied for the multiple reflections off the ground and walls. The prediction of the field distribution inside such environment is useful for the planning and deployment of a wireless radio and sensor system. Factors that affect the field strengths and distributions of radio waves in confined space were analyzed. The results could be used to evaluate the RF exposure safety in confined environment. By comparing the field distributions for various scenarios, it was observed that the Wi-Fi device counts, spacing and relative locations in the room are important factors in such environments. The RF Keep Out Zone (KOZ), where the electric field strengths exceed the permissible RF exposure limit, could be used to assess the RF human exposure compliance. As shown in this study, it s possible to maximize or minimize field intensity in specific area by arranging the Wi-Fi devices as a function of the relative location and spacing in a calculated manner.

Hwu, Shian U.↗
DOE OSTI2023

Updates to Composite Analysis Base Case and Null Space Monte Carlo Sensitivity Based on New Unit Dose Factors

This environmental calculation file (ECF) presents the results of the exposure route-specific and total radiological dose assessments for the groundwater exposure pathway as a part of the updated Composite Analysis for Low-Level Waste Disposal in the Hanford Site Central Plateau (FY 2022), based on revised unit dose factors (UDFs) published in CA Special Studies: Updates to the Groundwater Pathway Radiological Dose. The reason for these radiological dose assessments is to estimate the cumulative radiological impacts from all screened sources of ionizing radiation and exposure routes that could potentially contribute to the projected dose to a hypothetical member of the public. Sources of ionizing radiation can include existing or future disposal facilities and other sources including past-practice discharge sites. Additionally, the results of the exposure route-specific and total radiological dose assessments have been revised for the groundwater pathway based on the null space Monte Carlo (NSMC) groundwater concentrations and the most recent updates to the UDFs as a part an uncertainty analysis for the updated Hanford Site CA.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
NASA NTRS2010

Space Toxicology: Human Health during Space Operations

Space Toxicology is a unique and targeted discipline for spaceflight, space habitation and occupation of celestial bodies including planets, moons and asteroids. Astronaut explorers face distinctive health challenges and limited resources for rescue and medical care during space operation. A central goal of space toxicology is to protect the health of the astronaut by assessing potential chemical exposures during spaceflight and setting safe limits that will protect the astronaut against chemical exposures, in a physiologically altered state. In order to maintain sustained occupation in space on the International Space Station (ISS), toxicological risks must be assessed and managed within the context of isolation continuous exposures, reuse of air and water, limited rescue options, and the need to use highly toxic compounds for propulsion. As we begin to explore other celestial bodies in situ toxicological risks, such as inhalation of reactive mineral dusts, must also be managed.

Khan-Mayberry, Noreen↗
DOE OSTI2022

Calculation of Groundwater Pathway Radiological Dose for the Hanford Site Composite Analysis Base Case

The purpose of this environmental calculation file (ECF) is to present the results of the exposure route-specific and total radiological dose assessments for the groundwater exposure pathway as a part of the updated Hanford Site Composite Analysis (CA). The purpose of these radiological dose assessments is to provide an estimate of the cumulative radiological impacts from all screened sources of ionizing radiation and exposure routes that could potentially contribute to the projected dose to a hypothetical member of the public from both existing or future disposal facilities and other sources including past-practice discharge sites.

61 RADIATION PROTECTION AND DOSIMETRY↗
DOE OSTI2025

Technical Background and Validation Report on the Residential Water Inhalation Risk Calculator Presented in the Risk Assessment Information System

Indoor air quality (IAQ) is critical for human health. Poor IAQ is linked to respiratory issues, cardiovascular diseases, and cancer. Indoor pollutants are emitted by typical household items such as cleaning products, personal care items, building materials, and tap water - an understudied volatile organic compound (VOC) source. This document presents the Residential Water Inhalation Risk Calculator (RWIRC), which estimates daily VOC exposure concentrations from various household water uses, such as showering and dishwashing, to assess exposure risks for the most vulnerable occupant. Integrated into the Risk Assessment Information System (RAIS) and sponsored by the US Department of Energy (DOE), the calculator divides a house into three compartments: shower, bathroom, and other spaces, accounting for daily water usage patterns and calculating VOC concentrations. Exposure data generated using the calculator can assist health assessors in estimating excess lifetime cancer risk (ELCR) and hazard index (HI) from VOC inhalation. Unlike traditional exposure models that utilize Andelman’s constant, the RWIRC continuously assesses variability in VOC concentrations and environmental conditions using differential equations to track VOC concentrations and air exchange between compartments. The calculator also provides unique volatilization fractions for each chemical and appliance, enhancing accuracy of the exposure concentration estimation. The RWIRC is accessible online and allows users to customize parameters (i.e., number of bathrooms, water temperature, and exhaust fan conditions) and input VOC characteristics (i.e., tap water and ambient air concentrations). This document provides a step-by-step guide on implementing the calculator. It also provides comparisons with the ATSDR-SHOWER calculator, using eight VOCs with varying physicochemical properties to reveal differences in algorithms and output concentrations. Simulations also assess how bathroom door positions and exhaust fan usage affect VOC exposure. The calculator results can enhance EPA risk screening levels for inhalation exposure to VOCs from tap water, offering a sophisticated tool for assessing inhalation risks and improving public health protection.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2024

Estimated impacts of forest restoration scenarios on smoke exposures among outdoor agricultural workers in California

Abstract As wildfires continue to worsen across western United States, forest managers are increasingly employing prescribed burns as a way to reduce excess fuels and future wildfire risk. While the ecological benefits of these fuel treatments are clear, little is known about the smoke exposure tradeoffs of using prescribed burns to mitigate wildfires, particularly among at-risk populations. Outdoor agricultural workers are a population at increased risk of smoke exposure because of their time spent outside and the physical demands of their work. Here, we assess the smoke exposure impacts among outdoor agricultural workers resulting from the implementation of six forest management scenarios proposed for a landscape in the Central Sierra, California. We leverage emissions estimates from LANDIS-II to model daily PM 2.5 concentrations with the Hybrid Single Particle Lagrangian Integrated Trajectory Model (HYSPLIT) and link those to agricultural employment data from the Bureau of Labor Statistics. We find a u-shaped result, in that moderate amounts of prescribed burning result in the greatest reduction in total smoke exposure among outdoor agricultural workers, particularly during months of peak agricultural activity due to wildfire-specific smoke reductions. The reduction in total smoke exposure, relative to scenarios with the least amount of management, decreases as more prescribed burning is applied to the landscape due to the contributions of the fuel treatments themselves to overall smoke burden. The results of this analysis may contribute to preparedness efforts aimed at reducing smoke exposures among outdoor agricultural workers, while also informing forest management planning for this specific landscape.

Environmental Sciences & Ecology↗
NASA NTRSDate not supplied

Investigation of Speed and Altitude Effects on Sound Exposure Level Calculations for Multiple Helicopters

International and United States Federal regulations evaluate helicopter acoustic emissions for certification purposes as well as community noise impact assessments. The Sound Exposure Level (SEL) is a commonly used metric that represents the loudness of a single event, with a penalty for duration. For example, a flyover lasting ten seconds can have the same SEL as a five-second duration flyover that is 3 dB higher in peak level. Ten helicopters spanning the light and medium weight classes were modeled using flight test data. They were then virtually flown using the Advanced Acoustic Model at multiple speeds and altitudes. SEL and A-weighted SEL (SELA) were calculated at ground-based observer locations for each condition. Scaling laws with altitude are determined, and cruising airspeeds which result in the minimum SEL are found. Implications for future land-use planning will be discussed, and the relationships are reduced to general or vehicle-specific operational guidance for pilots.

community noise↗
NASA NTRS2006

The Interplay Between Strategic And Adaptive Control Mechanisms In Plastic Recalibration Of Locomotor Function

We have previously shown that viewing simulated rotary self-motion during treadmill locomotion causes immediate strategic modifications (Richards et al. 2004) as well as an after effect reflecting adaptive modification of the control of position and trajectory during over-ground locomotion (Mulavara et al. 2005). The process of sensorimotor adaptation is comprised of both strategic and adaptive control mechanisms. Strategic control involves cognitive, on-line corrections to limb movements once one is aware of a sensory discordance. Over an extended period of exposure to the sensory discordance, new strategic sensorimotor coordination patterns are reinforced until they become more automatic, and therefore adaptive, in nature. The objective of this study was to investigate how strategic changes in trunk control during exposure to simulated rotary self-motion during treadmill walking influences adaptive modification of locomotor heading direction during over-ground stepping. Subjects (n = 10) walked on a motorized linear treadmill while viewing a wide field-of-view virtual scene for 24 minutes. The scene was static for the first 4 minutes and then, for the last 20 minutes, depicted constant rate self-motion equivalent to walking in a counter-clockwise, circular path around the perimeter of a room. Subjects performed five stepping trials both before and after the exposure period to assess after effects. Results from our previous study showed a significant change in heading direction (HD) during post-exposure step tests that was opposite the direction in which the scene rotated during the adaptation period. For the present study, we quantified strategic modifications in trunk movement control during scene exposure using normalized root mean square (R(sub p)) variation of the subject's 3D trunk positions and normalized sum of standard deviations (R(sub o)) variation of 3D trunk orientations during scene rotation relative to that during static scene presentation. Associated 95% confidence intervals, CI(sub P) and CI(sub O), were calculated to investigate the variation of strategic modifications during scene exposure. Repeated measures ANOVA and individual subject regression analyses showed that R(sub P) and R(sub O) (i.e. strategic modifications) for trunk fore/aft (X) and yaw movements, respectively, decreased significantly over the exposure period. Furthermore, we found a significant correlation between the magnitude change in HD and the rate at which the variation of strategic modifications in trunk X decreased. We also found evidence of a correlation between HD and the rate at which strategic modifications in trunk yaw decreased (p = .06). We infer that adaptive recalibration of locomotor trajectory using optic flow stimuli depends on the rate at which strategic intervention is reduced.

Richards, J. T.↗
DOE OSTI2024

On alert for Ebola: public health risk assessment of travellers from Uganda to the USA during the 2022 outbreak

Abstract Background On 20 September 2022, the Ugandan Ministry of Health declared an outbreak of Ebola disease caused by Sudan ebolavirus. Methods From 6 October 2022 to 10 January 2023, Centers for Disease Control and Prevention (CDC) staff conducted public health assessments at five US ports of entry for travellers identified as having been in Uganda in the past 21 days. CDC also recommended that state, local and territorial health departments (‘health departments’) conduct post-arrival monitoring of these travellers. CDC provided traveller contact information, daily to 58 health departments, and collected health department data regarding monitoring outcomes. Results Among 11 583 travellers screened, 132 (1%) required additional assessment due to potential exposures or symptoms of concern. Fifty-three (91%) health departments reported receiving traveller data from CDC for 10 114 (87%) travellers, of whom 8499 (84%) were contacted for monitoring, 1547 (15%) could not be contacted and 68 (1%) had no reported outcomes. No travellers with high-risk exposures or Ebola disease were identified. Conclusion Entry risk assessment and post-arrival monitoring of travellers are resource-intensive activities that had low demonstrated yield during this and previous outbreaks. The efficiency of future responses could be improved by incorporating an assessment of risk of importation of disease, accounting for individual travellers’ potential for exposure, and expanded use of methods that reduce burden to federal agencies, health departments, and travellers.

General & Internal Medicine↗
NASA NTRS1992

Ceramic matrix composites for rocket engine turbine applications

A program to establish the potential for introducing fiber reinforced ceramic matrix composites (FRCMC) in future rocket engine turbopumps was instituted in 1987. A brief summary of the overall program (both contract and in-house research) is presented. Tests at NASA Lewis include thermal upshocks in a hydrogen/oxygen test rig capable of generating heating rates up to 2500 C/sec. Post thermal upshock exposure evaluation includes the measurement of residual strength and failure analysis. Test results for monolithic ceramics and several FRCMC are presented. Hydrogen compatibility was assessed by isothermal exposure of monolithic ceramics in high temperature gaseous hydrogen plus water vapor.

Herbell, Thomas P.↗
DOE OSTI2025

Developing and Demonstrating a Lab Method for Quantifying Hair Exposure to Environmental Tobacco Smoke with a Forensic Perspective

Forensic science and chemistry curricula often lack hands-on experimental designs that effectively simulate the impact of environmental tobacco smoke (ETS) or other common elements found at crime scenes, such as marijuana, on trace forensic evidence. Hair, a critical form of trace evidence, offers unique advantages for assessing long-term exposure to environmental pollutants, including ETS. This study presents a novel, noninvasive forensic laboratory module designed to evaluate ETS exposure on various human hair types (untreated, dyed, and bleached). The experimental procedure involved controlled cigarette smoke exposure, followed by analysis using UV−visible spectroscopy, FTIR spectroscopy, and zeta potential measurements. Thirteen students participated in the three-week lab module (three sessions per week). Pre- and postlab assessments were conducted to evaluate learning outcomes. The prelab assessment focused on baseline knowledge of forensic hair analysis, as well as student expectations and confidence. The postlab assessment evaluated knowledge gained, technical insights, application of techniques, self-reflection, conceptual understanding, and practical skill development. This design helped students comprehend the effects of chemical treatments that significantly influence hair’s capacity to adsorb ETS residues by altering its physical and chemical properties. Integration of this experiment into the forensic chemistry curriculum led to measurable gains in student understanding, technical competency, and appreciation for realworld forensic applications. This method offers a valuable teaching and investigative tool for assessing individual ETS exposure in forensic contexts.

FTIR↗