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At least 1,549 records · Page 86

Dynamic Analysis of Discoidal Nascent HDL Structure by IPET

Although circulating high density lipoproteins (HDL) are considered protective from cardiovascular disease, we have a remarkably limited understanding of their structure. In the recent decades, several models of HDL are built and debated each other, but the exact structure of HDL can't be confirmed even now. In our previous work, we used cross‐linking chemistry and mass spectrometry to generate detailed models of apoA‐I in reconstituted particles as well as “real” HDL from human plasma. Despite substantial differences in size and shape, these structures all shared the theme of an antiparallel belt‐like arrangement. Thus, direct visible observation of the conformation of discoidal HDL with the help of electron microscopy is a possible way to solve the debate. Here we report a study of structure of HDL by using negative‐staining electron microscopy and cryo‐electron microscopy as well as electron tomography. The 3D structures of dynamical individual HDL molecules are reconstructed by the individual‐particle electron tomography reconstruction (IPET). The reconstructed density maps at ~ 2 nm resolution display the size heterogeneity and conformation variety of HDL particles, and reveal a fusion/release mechanism of discoidal HDL in lipid transfer. These results revealed that apoA‐I makes highly specific contacts with itself to form a molecular scaffold that stabilizes HDL and facilitates, through specific protein: protein interactions, the association of HDL partner proteins to define particle function. The notion is crucial for us to further understand how the major HDL protein, apolipoprotein (apo)A‐I are involved in cholesterol transfer and lipid metabolism and cardiovascular disease. Support or Funding Information This work was supported by the National Heart, Lung, and Blood Institute of the National Institutes of Health (2R01 HL115153‐06, R01GM104427, and P01HL030086). Work conducted at the Molecular Foundry was supported by the Office of Basic Energy Sciences of the Office of Science at the U.S. Department of Energy under Contract No. DE‐AC02‐05CH11231 . This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .

Li, Jennifer Jinping↗

Estimating cross-field particle transport at the outer midplane of TCV by tracking filaments with machine learning

Abstract Cross-field transport of particles in the boundary region of magnetically confined fusion plasmas is dominated by turbulence. Blobs, intermittent turbulent structures with large amplitude and a filamentary shape appearing in the scrape-off layer (SOL), are known from theoretical and experimental studies to be the main contributor to the cross-field particle transport. The dynamics of blobs differs depending on various plasma conditions, including triangularity ( δ ). In this work, we analyze triangularity dependence of the cross-field particle transport at the outer midplane of plasmas with δ = + 0.38 , +0.15, −0.14, and −0.26 on the Tokamak à Configuration Variable, using our novel machine learning (ML) blob-tracking approach applied to gas puff imaging data. The cross-field particle flux determined in this way is of the same order as the overall transport inferred from KN1D, GBS, and SOLPS-ITER simulations, suggesting that the blobs identified by the ML blob-tracking account for most of the cross-field particle transport in the SOL. Also, the ML blob-tracking and KN1D show a decrease in the cross-field particle transport as δ becomes more negative. The blob-by-blob analysis of the result from the tracking reveals that the decrease of cross-field particle transport with decreasing δ is accompanied by a decrease in the number of blobs in a fixed time, which tend to have larger area and lower radial speed. Also, the blobs in these plasmas are in the connected sheath regime, and show a velocity scaling consistent with the two-region model.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

The evolution of orientation relationships during the transformation of a twin-free T-particle to tenfold T-twins in an Al alloy during homogenisation

Highlights: • The ORs of T-phase change continuously during its transformation to tenfold twins. • The changes in ORs are achieved by lattice rotations of T-phase about [010]{sub T} axis. • The OR change of T-phase exhibits a relationship with its cross-section shape. • The OR change of T-phase reduce the interface misfit increased by newly-formed twins. • Rotation of T-particle requires coordinate deformation at the near-interface region. - Abstract: The crystallographic and morphological analysis of T-phase formation in Al alloys was investigated using high-resolution electron microscopy (HRTEM) and selected-area electron diffraction pattern (SAEDP). The results show that the orientation relationships (ORs) of the T-phase change continuously from its original ORs during the transformation of a twin-free T-particle to the tenfold T-twins. These OR changes were achieved by lattice rotations of T-twin domains (T-TDs) about the [010]{sub T}//[010]{sub Al} axis by an angle ranging from 0° to 9°, and this exhibits a relationship with the shape of the cross-sections of the T-phase (T-CSs). The changes in ORs of the T-phase can reduce the increase in interface misfit between the newly-formed T-TDs and the Al matrix. The matrix could only accommodate the rotation of a T-particle at the near-interface region at relatively high temperatures.

36 MATERIALS SCIENCE↗

Particle-Image Velocimeter Having Large Depth of Field

An instrument that functions mainly as a particle-image velocimeter provides data on the sizes and velocities of flying opaque particles. The instrument is being developed as a means of characterizing fluxes of wind-borne dust particles in the Martian atmosphere. The instrument could also adapted to terrestrial use in measuring sizes and velocities of opaque particles carried by natural winds and industrial gases. Examples of potential terrestrial applications include monitoring of airborne industrial pollutants and airborne particles in mine shafts. The design of this instrument reflects an observation, made in field research, that airborne dust particles derived from soil and rock are opaque enough to be observable by use of bright field illumination with high contrast for highly accurate measurements of sizes and shapes. The instrument includes a source of collimated light coupled to an afocal beam expander and an imaging array of photodetectors. When dust particles travel through the collimated beam, they cast shadows. The shadows are magnified by the beam expander and relayed to the array of photodetectors. Inasmuch as the images captured by the array are of dust-particle shadows rather of the particles themselves, the depth of field of the instrument can be large: the instrument has a depth of field of about 11 mm, which is larger than the depths of field of prior particle-image velocimeters. The instrument can resolve, and measure the sizes and velocities of, particles having sizes in the approximate range of 1 to 300 m. For slowly moving particles, data from two image frames are used to calculate velocities. For rapidly moving particles, image smear lengths from a single frame are used in conjunction with particle- size measurement data to determine velocities.

Bos, Brent↗

Dynamic compaction of nickel powder examined by x-ray phase contrast imaging

Understanding the shock response of porous, granular materials is important for many scientific applications. In this work, a propagation-based x-ray phase contrast imaging technique was used to examine the shock compaction response of Ni powder (particle size: 30 and 45 µm), encapsulated in PMMA cylinders, in situ and in real time. The propagating shock wave in the PMMA cylinder and the deformation of the Ni powder column were recorded, but the compaction wave in the Ni powder could not be observed due to insufficient penetration of x-ray photons through the sample. The overall shape of the deformed Ni column downstream of the PMMA shock looked qualitatively similar for both particle sizes: it deformed inward and then outward similar to a converging-diverging nozzle, followed by a ‘mushroom’-like structure at the impact face. A preliminary analysis of our data using shock-polar method provided insight into the observed shock and flow deflection angles at the PMMA/Ni interface, and permitted evaluation of the Ni powder EOS used in this work.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Counting Characteristics of the Registration System for the Baksan Experiment on Sterile Transitions

— Counting characteristics of the system for recording rare events of the {sup 71}Ge decay in the radiochemical gallium Baksan Experiment on Sterile Transitions (BEST) are presented. Events are recorded simultaneously along eight counting channels in the energy range 0.3–16 keV, which include {sup 71}Ge decays in the region of L and K peaks with a total efficiency of up to 75%. The data analysis is based on the recording of the full shape of the leading edge of the charge pulses using a digital oscilloscope.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

New generation bunch shape monitor for ion accelerators

Measuring longitudinal beam parameters is important for operation and development of high intensity linear accelerators, but it is notoriously difficult for proton and ion beams at non-relativistic energies. The Bunch Shape Monitor (BSM) is a device used for measuring the longitudinal bunch distribution in ion linacs. The existing BSM models have poor electron collection efficiency from the wire and are limited to one-dimensional measurements of the phase coordinate. In response to this problem, we have developed a new generation BSM with improved performance. The proposed design incorporates three major innovations: First, the collection efficiency was improved by adding a focusing field between the wire and the entrance slit, which will also allow measurements over a much wider dynamic range. Second, an improvement in the measurement speed was achieved by sampling longitudinal profiles of multiple energy slices simultaneously, where the BSM wire is placed at the exit of an ion spectrometer so that ions with different energies hit the wire at different horizontal coordinates along the wire. Finally, the design incorporates a motion system that can shift the wire and deflecting cavity together, enabling transverse profile measurements like a wire scanner. Here, in this paper, we will provide the design of the new BSM and report on its beam test results at the Spallation Neutron Source facility in Oak Ridge National Laboratory.

43 PARTICLE ACCELERATORS↗

Radio to Gamma-Ray Emission from Shell-Type Supernova Remnants: Predictions from Non-Linear Shock Acceleration Models

Supernova remnants (SNRs) are widely believed to be the principal source of galactic cosmic rays, produced by diffusive shock acceleration in the environs of the remnant's expanding blast wave. Such energetic particles can produce gamma-rays and lower energy photons via interactions with the ambient plasma. The recently reported observation of TeV gamma-rays from SN1006 by the CANGAROO Collaboration, combined with the fact that several unidentified EGRET sources have been associated with known radio/optical/X-ray-emitting remnants, provides powerful motivation for studying gamma-ray emission from SNRs. In this paper, we present results from a Monte Carlo simulation of non-linear shock structure and acceleration coupled with photon emission in shell-like SNRs. These non-linearities are a by-product of the dynamical influence of the accelerated cosmic rays on the shocked plasma and result in distributions of cosmic rays which deviate from pure power-laws. Such deviations are crucial to acceleration efficiency considerations and impact photon intensities and spectral shapes at all energies, producing GeV/TeV intensity ratios that are quite different from test particle predictions.

Baring, Matthew G.↗

Elimination of QCD Renormalization Scale and Scheme Ambiguities

The setting of the renormalization scale (μ r ) in the perturbative QCD (pQCD) is one of the crucial problems for achieving precise fixed-order pQCD predictions. The conventional prescription is to take its value as the typical momentum transfer Q in a given process, and theoretical uncertainties are then evaluated by varying it over an arbitrary range. The conventional scale-setting procedure introduces arbitrary scheme-and-scale ambiguities in fixed-order pQCD predictions. The principle of maximum conformality (PMC) provides a systematic way to eliminate the renormalization scheme-and-scale ambiguities. The PMC method has rigorous theoretical foundations; it satisfies the renormalization group invariance (RGI) and all of the self-consistency conditions derived from the renormalization group. The PMC has now been successfully applied to many physical processes. In this paper, we summarize recent PMC applications, including event shape observables and heavy quark pair production near the threshold region in e + e – annihilation and top-quark decay at hadronic colliders. In addition, estimating the contributions related to the uncalculated higher-order terms is also summarized. These results show that the major theoretical uncertainties caused by different choices of μ r are eliminated, and the improved pQCD predictions are thus obtained, demonstrating the generality and applicability of the PMC.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

The three-point energy correlator in the coplanar limit

Energy correlators are a type of observables that measure how energy is distributed across multiple detectors as a function of the angles between pairs of detectors. In this paper, we study the three-point energy correlator (EEEC) at lepton colliders in the three-particle near-to-plane (coplanar) limit. The leading-power contribution in this limit is governed by the three-jet (trijet) configuration. We introduce a new approach by projecting the EEEC onto the volume of the parallelepiped formed by the unit vectors aligned with three detected final-state particles. Analogous to the back-to-back limit of the two-point energy correlator probing the dijet configuration, the small-volume limit of the EEEC probes the trijet configuration. We derive a transverse momentum dependent (TMD) based factorization theorem that captures the soft and collinear logarithms in the coplanar limit, which enables us to achieve the next-to-next-to-next-to-leading logarithm (N 3 LL) resummation. To our knowledge, this is the first N 3 LL result for a trijet event shape. Additionally, we demonstrate that a similar factorization theorem can be applied to the fully differential EEEC in the three-particle coplanar limit, which provides a clean environment for studying different coplanar trijet shapes.

Effective Field Theories of QCD↗

Differential effect of magnetic alignment on additive manufacturing of magnetocaloric particles

Additive manufacturing of materials using magnetic particles as feedstock has attracted tremendous attention during the past decade owing to its ability to tune both shape and magnetocrystalline anisotropy, which can significantly enhance the magnetic characteristics of materials. We demonstrate that the magnetic response of multilayered thin films of Gd5Si4 can be tailored by controlling the external magnetic field during inkjet printing. The external magnetic field aligns the magnetic particles along their magnetic easy axis, enhancing the magnetic anisotropy of the printed films. Our work demonstrates the ability to print thin magnetic films with a defined anisotropy in any chosen direction with the potential to approaching magnetic properties of corresponding single crystalline materials.

36 MATERIALS SCIENCE↗

Radiative Particle-in-Cell Simulations of Turbulent Comptonization in Magnetized Black-Hole Coronae

We report results from the first radiative particle-in-cell simulations of strong Alfvénic turbulence in plasmas of moderate optical depth. The simulations are performed in a local 3D periodic box and self-consistently follow the evolution of radiation as it interacts with a turbulent electron-positron plasma via Compton scattering. We focus on the conditions expected in magnetized coronae of accreting black holes and obtain an emission spectrum consistent with the observed hard state of Cyg X-1. Most of the turbulence power is transferred directly to the photons via bulk Comptonization, shaping the peak of the emission around 100 keV. The rest is released into nonthermal particles, which generate the MeV spectral tail. As a result, the method presented here shows promising potential for ab initio modeling of various astrophysical sources and opens a window into a new regime of kinetic plasma turbulence.

79 ASTRONOMY AND ASTROPHYSICS↗

Pedestal particle balance studies in JET-ILW H-mode plasmas

JET-ILW type I ELMy H-modes at 2.5 MA/2.8 T with constant NBI heating (23 MW) and gas fuelling rate were performed, utilising edge localised mode (ELM) pacing by vertical kicks and plasma shaping (triangularity, δ) as tools to disentangle the effects of ELMs, inter-ELM transport and edge stability on the pedestal particle balance. In agreement with previous studies, the pedestal confinement improves with increasing δ, mostly due to a significant increase in pedestal density while the ELM frequency ($f_{\mathrm{ELM}}$) is decreased. Improved pedestal confinement with increasing δ was observed even when the pedestal MHD stability was degraded artificially by vertical kicks, implying that increased triangularity may favourably affect the inter-ELM pedestal recovery. The workflow developed to quantify the pedestal particle balance uses high time-resolution profile reflectometry to characterise the inter-ELM evolution of the plasma particle content ($\mathrm{d} N/\mathrm{d}t$), the NEO drift-kinetic solver to evaluate the neoclassical fluxes and interpretative EDGE2D-EIRENE simulations to estimate the edge particle source. The edge particle source is then constrained by deuterium Balmer-α line intensity measurements in the main chamber, which are, however, strongly affected by reflections from the metal walls. The reflections are accounted for by the CHERAB code taking the divertor emission (the brightest light source in the torus) distribution from imaging spectroscopy measurements as input. Our analysis shows that in the second half of the ELM cycle, the volume-integrated particle source is larger than $\mathrm{d} N/\mathrm{d}t$, indicating that transport plays a key role in the inter-ELM pedestal recovery.

fuelling↗

Tricoupled hybrid lattice Boltzmann model for nonisothermal drying of colloidal suspensions in micropore structures

A tricoupled hybrid lattice Boltzmann model (LBM) is developed to simulate colloidal liquid evaporation and colloidal particle deposition during the nonisothermal drying of colloidal suspensions in micropore structures. An entropic multiple-relaxation-time multirange pseudopotential two-phase LBM for isothermal interfacial flow is first coupled to an extended temperature equation for simulating nonisothermal liquid drying. Then the coupled model is further coupled with a modified convection diffusion equation to consider the nonisothermal drying of colloidal suspensions. Two drying examples are considered. First, drying of colloidal suspensions in a two-pillar micropore structure is simulated in two dimensions (2D), and the final configuration of colloidal particles is compared with the experimental one. Good agreement is observed. Second, at the temperature of 343.15 K ( 70°C ), drying of colloidal suspensions in a complex spiral-shaped micropore structure containing 220 pillars is simulated (also in 2D). The drying pattern follows the designed spiral shape due to capillary pumping, i.e., transport of the liquid from larger pores to smaller ones by capillary pressure difference. Because the colloidal particles are passively carried with liquid, they accumulate at the small menisci as drying proceeds. As liquid evaporates at the small menisci, colloidal particles are deposited, eventually forming solid structures between the pillars (primarily), and at the base of the pillars (secondarily). As a result, the particle deposition conforms to the spiral route. Qualitatively, the simulated liquid and particle configurations agree well with the experimental ones during the entire drying process. Quantitatively, the model demonstrates that the evaporation rate and the particle accumulation rate slowly decrease during drying, similar to what is seen in the experimental results, which is due to the reduction of the liquid-vapor interfacial area. In conclusion, the hybrid model shows the capability and accuracy for simulating nonisothermal drying of colloidal suspensions in a complex micropore structure both qualitatively and quantitatively, as it includes all the required physics and captures all the complex features observed experimentally. Such a tricoupled LBM has a high potential to become an efficient numerical tool for further investigation of real and complex engineering problems incorporating drying of colloidal suspensions in porous media.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Impact of Powder Variability on the Microstructure and Mechanical Behavior of Selective Laser Melted Alloy 718

Powder-bed additive manufacturing processes use fine powders to build parts layer-by-layer. Alloy 718 powder feedstocks for selective laser melting (SLM) additive manufacturing are produced commercially by both gas and rotary atomization and are available typically in the 10-45 or 15-45 microns size ranges. A comprehensive investigation was conducted to understand the impact of powder variability on the microstructure and mechanical behavior of SLM 718 heat treated to Aerospace Material Specification (AMS) 5664. This study included sixteen virgin powders and three once-recycled powders within the 10-45 and 15-45 microns size ranges that were obtained from seven direct source suppliers and one reseller. Although alike as highly regular spheroids, these powders showed distinct differences in composition (especially Al, C and N contents), particle size distributions, and powder features such as degree of agglomeration, fusion and surface roughness. Compositional differences expectedly had the strongest impact on microstructure. High N and C contents formed TiN-nitrides and/or (Nb,Ti,Mo)-C carbides on the grain boundaries, prevented recrystallization during heat treatment, and resulted in retained (001)-scalloped shaped grains that ranged from 19 to 41 microns in average size. In the absence of this particle pinning, the average grain size of the heat treated SLM 718 ranged from 51 microns to 90 microns. Room temperature tensile and high cycle fatigue (HCF) testing compared as-fabricated (AF) and low stress ground (LSG) surface conditions. Tensile testing revealed consistent behavior between the two surface conditions and amongst the powder lots. The finer grained SLM 718 builds displayed the lowest tensile properties. A SLM 718 build fabricated from a powder with eight times lower C content showed statistically better tensile properties presumably due to enhanced coarsening of (delta)-Ni3Nb precipitates. The specimens from once-recycled powders had slightly higher tensile strengths and slightly higher ductility compared to their virgin equivalents; once-recycling also did not substantially degrade the mean HCF life. The LSG fatigue lives agreed with conventionally manufactured 718 data, while AF lives exhibited a knock-down due to surface roughness. The fatigue lives of AF specimens were statistically equivalent across powder lots except for one and failures typically initiated at stress concentrators associated with SLM surface asperities. Fatigue testing of low stress ground specimens result in both transgranular and within facet crack initiations. More than half of the cracks initiated from these facets for the machined condition; however, these facets appeared to be within grains that were larger-than-average in size. A nitrogen-atomized powder with fine prior particles of TiN-nitrides and M(Ti,Nb,Mo)C carbides from atomization on powder surfaces resulted in the best fatigue performance with segregation of these particles to the SLM 718 grain boundaries leading to higher resistance to early-stage crack propagation. Typically the fine-grained builds with minor phases along the grain boundaries did not perform well in fatigue, whereas a larger-grain build with lower carbon content and coarser delta-Ni3Nb precipitates showed the next best HCF response. Further details of the build microstructure and its impact on tensile and fatigue behavior was considered.

laser deposition↗

Adaptive methods of generating complex light arrays

Structured light arrays of various shapes have been a cornerstone in optical science, driven by the complexities of precise and adaptable generation. This study introduces an approach using a spatial light modulator (SLM) as a generator for these arrays. By projecting a holographic mask onto the SLM, it functions simultaneously as an optical convolution device, focusing mechanism, and structured light beam mask. Our approach offers unmatched versatility, allowing for the experimental fabrication of traditional beam arrays like azimuthal Laguerre–Gaussian (LG), Bessel–Gaussian (BG), and Hermite–Gauss (HG) in the far-field. Notably, it has enabled a method of generating Ince–Gauss (IG) and LG radial mode beam arrays using a convolution solution. Our system provides exceptional control over array periodicity and intensity distribution, bypassing the Talbot self-imaging phenomenon seen in traditional setups. We provide an in-depth theoretical discussion, supported by empirical evidence, of our far-field results. This method has vast potential for applications in optical communication, data processing, and multi-particle manipulation. It paves the way for rapid generation of structured light with high spatial frequencies and complex shapes, promising transformative advances in these domains.

Optics↗

Topographic controls on a phreatomagmatic maar-diatreme eruption: field and numerical results from the Holocene Dotsero volcano (Colorado, USA)

We analyzed the eruptive products of Holocene Dotsero volcano (Colorado, USA; ~4.15 ka), which recorded evidence of a progression from effusive magmatic activity through explosive phreatomagmatic maar-forming activity to a final explosive magmatic phase. The nature of the deposits suggests that the irregular and mountainous pre-eruptive topography strongly influenced the formation of directed pyroclastic density currents (PDCs) during the phreatomagmatic phase, where the topographically high northern crater rim acted as a barrier and promoted transport to the south. Furthermore, the crater shape strongly controlled the grain size of the final deposits, providing further evidence that deposit grain size can be a misleading proxy for fragmentation or explosion intensity. We test these hypotheses, as gleaned from fieldwork, by implementing a multiphase numerical model to simulate discrete explosions and their resulting PDCs at maar-diatreme volcanoes. We confirm that a crater shape where one rim is higher than the other promotes multiple pulses of particle transport in the direction of the lower rim. The initial PDCs contain both coarse and fine particles, whereas PDCs generated by later pulses contain, predominately, finer particles. This mechanism provides an alternative explanation to the formation of lapilli tuff/tuff couplets often found at maar-diatreme tephra rings (including Dotsero volcano). Additional modeling shows how the crater depth can control grain size of the resulting PDC deposits. In the case of a deep crater and a relatively weak explosion, it is possible that only the fine particles escape following collapse of the eruptive column, resulting in a fine-grained deposit. This work allows us to improve models developed to describe emplacement of PDCs for different crater geometries and informs on the dynamics of maar-diatreme eruptions, but also highlights the limitations of our knowledge of key parameters, especially those related to the processes of magma-water interaction and syn-eruptive hydrogeology, during such events.

58 GEOSCIENCES↗

Data on Cu- and Ni-Si-Mn-rich solute clustering in a neutron irradiated austenitic stainless steel

The data presented in this article is supplementary to the research article “Phase instabilities in austenitic steels during particle bombardment at high and low dose rates” (Levine et al.). Needle-shaped samples were prepared with focused ion beam milling from a 304L stainless steel that was irradiated with fast neutrons (E 0.1 MeV) in the BOR-60 reactor at 318 °C to 47.5 dpa. Atom probe tomography (APT) experiments in voltage mode were then conducted on a Cameca LEAP 5000X HR. Atom position, range, and mass spectrum files after reconstruction with Cameca’s IVAS software are included. Cu- and Ni-Si-Mn-rich solute nanoclusters were identified and analyzed using the Open Source Characterization of APT Reconstructions (OSCAR) program. Python code for OSCAR, information on the program’s underlying algorithm, and sample output files are provided. A proximity histogram of a Ni-Si-Mn-rich cluster and a 1D density/solute concentration profile of a Cu-rich cluster are given to demonstrate OSCAR’s analytical functionalities. The provided APT dataset is valuable for benchmarking phase instabilities in neutron-irradiated austenitic stainless steels that occur at high doses. The OSCAR program can be reused to process other APT data sets where solute nanoclustering is of interest.

42 ENGINEERING↗