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NASA NTRS2007

Development of the Functional Flow Block Diagram for the J-2X Rocket Engine System

The J-2X program calls for the upgrade of the Apollo-era Rocketdyne J-2 engine to higher power levels, using new materials and manufacturing techniques, and with more restrictive safety and reliability requirements than prior human-rated engines in NASA history. Such requirements demand a comprehensive systems engineering effort to ensure success. Pratt & Whitney Rocketdyne system engineers performed a functional analysis of the engine to establish the functional architecture. J-2X functions were captured in six major operational blocks. Each block was divided into sub-blocks or states. In each sub-block, functions necessary to perform each state were determined. A functional engine schematic consistent with the fidelity of the system model was defined for this analysis. The blocks, sub-blocks, and functions were sequentially numbered to differentiate the states in which the function were performed and to indicate the sequence of events. The Engine System was functionally partitioned, to provide separate and unique functional operators. Establishing unique functional operators as work output of the System Architecture process is novel in Liquid Propulsion Engine design. Each functional operator was described such that its unique functionality was identified. The decomposed functions were then allocated to the functional operators both of which were the inputs to the subsystem or component performance specifications. PWR also used a novel approach to identify and map the engine functional requirements to customer-specified functions. The final result was a comprehensive Functional Flow Block Diagram (FFBD) for the J-2X Engine System, decomposed to the component level and mapped to all functional requirements. This FFBD greatly facilitates component specification development, providing a well-defined trade space for functional trades at the subsystem and component level. It also provides a framework for function-based failure modes and effects analysis (FMEA), and a rigorous baseline for the functional architecture.

White, Thomas↗

DOE OSTI2026

Toward Muon Neutrino Charged-Current Neutral Pion Cross Section Measurements at ICARUS

At ICARUS and the broader Short-Baseline Neutrino Program, few neutrino interaction channels offer as much utility as those producing neutral pions, which are an important background to electron neutrino searches and provide a standard candle for calibrating the electromagnetic shower energy scale. Beyond this, measurements of neutrino-induced neutral pions offer a probe of resonant interactions that are relevant to future accelerator neutrino experiments like the Deep Underground Neutrino Experiment. In this document, a measurement of charged-current muon neutrino interactions in liquid argon with a single neutral pion in the final state is presented, making use of neutrino interaction events recorded with the ICARUS T600 detector at Fermilab while exposed to the Booster Neutrino Beam. Event selection is carried out with a fully-automated machine learning reconstruction framework, allowing for the extraction of single-differential cross section measurements as a function of muon and neutral pion kinematic observables.

Carber, Dan [Colorado State U.]↗

NASA NTRS1986

Models of polarized infrared emission from bipolar nebulae

Many stars with circumstellar dust shells show a high degree of linear polarization (Sato et al. 1985). We are developing a model which assumes that the polarization arises from scattering by circumstellar dust. Our model assumes a geometry in which the star is surrounded by an optically thin spherical dust shell and embedded within an optically thick disk. This geometry is consistent with that proposed for objects with bipolar molecular outflow. This is important because many bipolar flow objects have also been observed to be highly polarized. The high degree of linear polarization is produced because the disk differentially attenuates the light from the star. The light incident from the point source is attenuated by a factor of exp(-tau/cos theta) where theta is the angle between a ray from the point source to the scatterer and a ray normal to the disk; tau is the optical depth at the wavelength of interest. Hence, the light scattered from the regions directly above and below the disk give the largest contribution to the total flux. The scattering angle for light from these regions is near 90 deg., so the light is strongly polarized and, in the Rayleigh scattering regime, is polarized parallel to the disk. The Stokes parameters for the scattered light from each particle in the shell are calculated by using the scattering matrix elements generated by a Mie scattering program. After the Stokes parameters for each particle are computed they are summed to give the Stokes parameters for the entire shell. Two graphs are presented which show the intensity and polarization spectrum generated by our model using the optical constants for astronomical silicates as defined by Draine and Lee (1984).

Burns, M. S.↗

NASA NTRS2000

Emergency flight control system using one engine and fuel transfer

A system for emergency aircraft control uses at least one engine and lateral fuel transfer that allows a pilot to regain control over an aircraft under emergency conditions. Where aircraft propulsion is available only through engines on one side of the aircraft, lateral fuel transfer provides means by which the center of gravity of the aircraft can be moved over to the wing associated with the operating engine, thus inducing a moment that balances the moment from the remaining engine, allowing the pilot to regain control over the aircraft. By implementing the present invention in flight control programming associated with a flight control computer (FCC), control of the aircraft under emergency conditions can be linked to the yoke or autopilot knob of the aircraft. Additionally, the center of gravity of the aircraft can be shifted in order to effect maneuvers and turns by spacing such center of gravity either closer to or farther away from the propelling engine or engines. In an alternative embodiment, aircraft having a third engine associated with the tail section or otherwise are accommodated and implemented by the present invention by appropriately shifting the center of gravity of the aircraft. Alternatively, where a four-engine aircraft has suffered loss of engine control on one side of the plane, the lateral fuel transfer may deliver the center of gravity closer to the two remaining engines. Differential thrust between the two can then control the pitch and roll of the aircraft in conjunction with lateral fuel transfer.

Burcham, Jr., Frank W.↗

NASA NTRS2012

Airborne Lidar Measurements of Atmospheric Pressure Made Using the Oxygen A-Band

Accurate measurements of greenhouse gas mixing ratios on a global scale are currently needed to gain a better understanding of climate change and its possible impact on our planet. In order to remotely measure greenhouse gas concentrations in the atmosphere with regard to dry air, the air number density in the atmosphere is also needed in deriving the greenhouse gas concentrations. Since oxygen is stable and uniformly mixed in the atmosphere at 20.95%, the measurement of an oxygen absorption in the atmosphere can be used to infer the dry air density and used to calculate the dry air mixing ratio of a greenhouse gas, such as carbon dioxide or methane. OUT technique of measuring Oxygen uses integrated path differential absorption (IPDA) with an Erbium Doped Fiber Amplifier (EDF A) laser system and single photon counting module (SPCM). It measures the absorbance of several on- and off-line wavelengths tuned to an O2 absorption line in the A-band at 764.7 nm. The choice of wavelengths allows us to maximize the pressure sensitivity using the trough between two absorptions in the Oxygen A-band. Our retrieval algorithm uses ancillary meteorological and aircraft altitude information to fit the experimentally obtained lidar O2 line shapes to a model atmosphere and derives the pressure from the profiles of the two lines. We have demonstrated O2 measurements from the ground and from an airborne platform. In this paper we will report on our airborne measurements during our 2011 campaign for the ASCENDS program.

Riris, Haris↗

NASA NTRS2024

SMAnalytics Automated Shape Memory Test Analysis Software User's Manual: UCFTC, UPER, and DSC Test Methods, Version 1.0.2

Over the course of 60 years of shape memory alloy research and development, the properties of these alloys have been measured using various testing methods, which are often customized by the organization performing the test. However, commercial adoption of shape memory alloys in aeronautic actuator applications requires reducing property uncertainty through standardizing test methods. Historically, differential scanning calorimetry (DSC) has been used to measure transformation temperatures under stress-free conditions. This testing method is well established, and tests are run under the applicable standard, ASTM F2004-17: Standard Test Method for Transformation Temperature of Nickel-Titanium Alloys by Thermal Analysis. Two other test methods for measuring strains and transformation temperatures under constant load or free recovery after prestraining have only recently been standardized—ASTM E3097: Standard Test Method for Mechanical Uniaxial Constant Force Thermal Cycling of SMAs (UCFTC) and ASTM E3098: Standard Test Method for Mechanical Uniaxial Pre-Strain and Thermal Free Recovery of SMAs (UPFR). These standards represent a critical step forward in producing reliable material property data for the use of these alloys in aeronautics and other commercial areas. However, no standard programs or software packages were previously available for postprocessing UCFTC- and UPFR-type test data to extract property data. Each organization that performed the testing analyzed data using its own custom manual methods, such as using a plot and a straight edge, spreadsheet plotting methods, or custom code routines, to extract the required values for strains, stresses, and transformation temperatures. SMAnalytics represents the first publicly available uniform software package for processing data generated using the DSC, UCFTC, and UPFR test methods, as well as many modifications of these methods, including loading in martensite versus austenite and performing multiple thermal cycles at stress. In doing so, it provides a tool for reducing potential error or variability in the measured values due to the precision of the technique used and person-to-person variability. It is also expected that this automated data-parsing tool can accelerate the data analysis phase of the test campaign, especially for large data files. This User’s Manual describes how the SMAnalytics software works and the method for its use.

Shape Memory Alloy↗

DOE OSTI2013

PETSc Users Manual (Rev. 3.3)

This manual describes the use of PETSc for the numerical solution of partial differential equations and related problems on high-performance computers. The Portable, Extensible Toolkit for Scientific Computation (PETSc) is a suite of data structures and routines that provide the building blocks for the implementation of large-scale application codes on parallel (and serial) computers. PETSc uses the MPI standard for all message-passing communication. PETSc includes an expanding suite of parallel linear, nonlinear equation solvers and time integrators that may be used in application codes written in Fortran, C, C++, Python, and MATLAB (sequential). PETSc provides many of the mechanisms needed within parallel application codes, such as parallel matrix and vector assembly routines. The library is organized hierarchically, enabling users to employ the level of abstraction that is most appropriate for a particular problem. By using techniques of object-oriented programming, PETSc provides enormous flexibility for users. PETSc is a sophisticated set of software tools; as such, for some users it initially has a much steeper learning curve than a simple subroutine library. In particular, for individuals without some computer science background, experience programming in C, C++ or Fortran and experience using a debugger such as gdb or dbx, it may require a significant amount of time to take full advantage of the features that enable efficient software use. However, the power of the PETSc design and the algorithms it incorporates may make the efficient implementation of many application codes simpler than “rolling them” yourself; For many tasks a package such as MATLAB is often the best tool; PETSc is not intended for the classes of problems for which effective MATLAB code can be written. PETSc also has a MATLAB interface, so portions of your code can be written in MATLAB to “try out” the PETSc solvers. The resulting code will not be scalable however because currently MATLAB is inherently not scalable; and PETSc should not be used to attempt to provide a “parallel linear solver” in an otherwise sequential code. Certainly all parts of a previously sequential code need not be parallelized but the matrix generation portion must be parallelized to expect any kind of reasonable performance. Do not expect to generate your matrix sequentially and then “use PETSc” to solve the linear system in parallel. Since PETSc is under continued development, small changes in usage and calling sequences of routines will occur. PETSc is supported; see the web site http://www.mcs.anl.gov/petsc for information on contacting support. A http://www.mcs.anl.gov/petsc/publications may be found a list of publications and web sites that feature work involving PETSc. We welcome any reports of corrections for this document.

97 MATHEMATICS AND COMPUTING↗

DOE OSTI2014

PETSc Users Manual (Rev. 3.4)

97 MATHEMATICS AND COMPUTING↗

DOE OSTI2014

PETSc Users Manual (Rev. 3.5)

This manual describes the use of PETSc for the numerical solution of partial differential equations and related problems on high-performance computers. The Portable, Extensible Toolkit for Scientific Computation (PETSc) is a suite of data structures and routines that provide the building blocks for the implementation of large-scale application codes on parallel (and serial) computers. PETSc uses the MPI standard for all message-passing communication. PETSc includes an expanding suite of parallel linear, nonlinear equation solvers and time integrators that may be used in application codes written in Fortran, C, C++, Python, and MATLAB (sequential). PETSc provides many of the mechanisms needed within parallel application codes, such as parallel matrix and vector assembly routines. The library is organized hierarchically, enabling users to employ the level of abstraction that is most appropriate for a particular problem. By using techniques of object-oriented programming, PETSc provides enormous flexibility for users. PETSc is a sophisticated set of software tools; as such, for some users it initially has a much steeper learning curve than a simple subroutine library. In particular, for individuals without some computer science background, experience programming in C, C++ or Fortran and experience using a debugger such as gdb or dbx, it may require a significant amount of time to take full advantage of the features that enable efficient software use. However, the power of the PETSc design and the algorithms it incorporates may make the efficient implementation of many application codes simpler than “rolling them” yourself. ;For many tasks a package such as MATLAB is often the best tool; PETSc is not intended for the classes of problems for which effective MATLAB code can be written. PETSc also has a MATLAB interface, so portions of your code can be written in MATLAB to “try out” the PETSc solvers. The resulting code will not be scalable however because currently MATLAB is inherently not scalable; and PETSc should not be used to attempt to provide a “parallel linear solver” in an otherwise sequential code. Certainly all parts of a previously sequential code need not be parallelized but the matrix generation portion must be parallelized to expect any kind of reasonable performance. Do not expect to generate your matrix sequentially and then “use PETSc” to solve the linear system in parallel. Since PETSc is under continued development, small changes in usage and calling sequences of routines will occur. PETSc is supported; see the web site http://www.mcs.anl.gov/petsc for information on contacting support. A http://www.mcs.anl.gov/petsc/publications may be found a list of publications and web sites that feature work involving PETSc. We welcome any reports of corrections for this document.

97 MATHEMATICS AND COMPUTING↗

NASA NTRS2001

Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability

Cell growth, differentiation and death are directed in large part by extracellular signaling through the interactions of cells with other cells and with the extracellular matrix; these interactions are in turn modulated by cytokines and growth factors, i.e. the microenvironment. Here we discuss the idea that extracellular signaling integrates multicellular damage responses that are important deterrents to the development of cancer through mechanisms that eliminate abnormal cells and inhibit neoplastic behavior. As an example, we discuss the action of transforming growth factor beta (TGFB1) as an extracellular sensor of damage. We propose that radiation-induced bystander effects and genomic instability are, respectively, positive and negative manifestations of this homeostatic process. Bystander effects exhibited predominantly after a low-dose or a nonhomogeneous radiation exposure are extracellular signaling pathways that modulate cellular repair and death programs. Persistent disruption of extracellular signaling after exposure to relatively high doses of ionizing radiation may lead to the accumulation of aberrant cells that are genomically unstable. Understanding radiation effects in terms of coordinated multicellular responses that affect decisions regarding the fate of a cell may necessitate re-evaluation of radiation dose and risk concepts and provide avenues for intervention.

NASA Discipline Radiation Health↗

DOE OSTI2017

Post Irradiation Examination of SiC Tube Subjected to Simultaneous Irradiation and Radial High Heat Flux

Silicon carbide (SiC) based composite is considered among leading candidate materials for accident tolerant fuel (ATF) cladding in light water reactors (LWRs) because of its outstanding irradiation and oxidation resistance, as well as low neutron absorption. Under normal operation conditions, the synergism between neutron irradiation and a high radial heat flux though the cladding thickness is expected to produce significant stress. This stress is attributed to a significant through-thickness temperature gradient and the resulting differential swelling strain due the highly temperature-dependent point-defect swelling of SiC. Although modeling of the in-pile stress state of SiC cladding has been conducted using finite element analysis, the analysis is challenging because of the complex stress state that depends upon swelling, irradiation creep, and thermal conductivity, all of which are both temperature and dose-dependent. These integral models have not yet been verified by experiments. In order to experimentally validate the multi-physics thermo-mechanical models of ATF SiC cladding during operation, SiC tube specimens have been irradiated under a high radial heat flux. This paper reports preliminary results from the post-irradiation examination (PIE) in on-going project supported by the U.S. Department of Energy's Nuclear Science User Facility program. The objectives of the PIE are (1) determination of the irradiation temperature distribution within the tube specimens, and (2) evaluation of the state and magnitude of the stress within the tube specimens arising from the temperature gradient. This paper mainly presents findings for objective (1)

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

DOE OSTI2019

Chapter Six - Derivation, cross-validation, and comparison of analytic formulas for electrostatic deflector aberrations

Here, we derived first and second order analytic aberration formulas in the horizontal transverse plane for an electrostatic deflector specified by the reference orbit radius, the central angle spanning the deflector, and its inhomogeneity coefficients. The derivation was performed using an iterative order-by-order perturbation method in a Frenet–Serret beamline coordinate system. We produced a C program edabrt for calculation of the first and second order aberrations using the formulas that we derived. The electrostatic deflector aberration formulas from Wollnik (1965) disagree with COSY INFINITY and the aberration formulas that we derived here, and they also deviate from the first and second order symplecticity conditions. The reason for this discrepancy is that the aberration formulas from Wollnik (1965) consider only motion in the main field of the deflector and do not properly account for fringe field effects, in particular the necessarily occurring change of kinetic energy due to the change in potential. The code GIOS uses electrostatic aberration formulas from Wollnik (1965) and exhibits the same discrepancy. We performed a comparison of first and second order electrostatic deflector aberrations for (1) the analytic formulas derived in this work, (2) differential-algebraic (DA) numerical integration of the equations of motion using the code COSY INFINITY, (3) the aberration formulas from Wollnik (1965), (4) aberrations computed using the code GIOS, and (5) the aberration formulas from Wollnik (1965) adjusted to account for the occurring change in potential. An electrostatic spherical deflector and an electrostatic cylindrical deflector were used as test cases for this comparison. There is excellent agreement between methods (1), (2), and (5), and these three methods satisfy the first and second order symplecticity conditions.

43 PARTICLE ACCELERATORS↗

DOE OSTI2018

Personnel Certifications for the Design, Installation and Maintenance of Photovoltaic Systems. Final Technical Report

The North American Board of Certified Energy Practitioners (NABCEP) is the most respected, well-established, and widely recognized national certification organization for professionals in the field of renewable energy. NABCEP’s certifications were created to facilitate consumer protection, improve quality assurance, and help employers judge the skills of existing or potential employees. The certifications also allow individuals to differentiate themselves from others in their field and advance their careers while fostering increased recognition of the profession. Since NABCEP’s founding in 2002, all of its certification exams have been administered in paper-and-pencil format twice per year at 30 exam sites around the United States. The biannual test administration and relatively low number of exam sites make it challenging for many qualified renewable energy professionals to take NABCEP’s certification exams. The rigorous nature of the exam, which leads to many candidates failing the exam on their first and sometimes second attempts, combined with the low number of annual test administrations means that anyone who fails will need to wait another six months for the chance to retake the exam. These factors limited the potential growth of NABCEP’s certification programs and the resultant quality assurance within the renewable energy industry. Thanks to a generous grant by the Department of Energy’s Solar Training and Education for Professional (STEP) program, NABCEP recently began updating its Photovoltaic (PV) Installation Professional Exam and developing three new specialty certifications in PV design, PV installation, and PV commissioning & maintenance. One of the primary objectives of this STEP-funded project was to develop the exams using a computer-based testing (CBT) model to increase the number of exam administrations and available exam sites for NABCEP’s certification exams. To successfully complete this project, NABCEP partnered with Castle Worldwide, Inc. With more than 25 years of experience in test development, test administration, analysis of examinations, and has a staff of 70 experienced personnel, NABCEP was confident that Castle’s team was more than qualified to help NABCEP make the transition to CBT examinations. NABCEP and Castle Worldwide jointly developed a project management plan that included key deliverables, scope management, a work breakdown structure, roles and responsibilities, and a project schedule with milestones. The project schedule was carefully monitored to ensure that activities along the critical path were not delayed and, when deemed necessary, the project was crashed to add resources so that activities could occur in parallel. NABCEP and Castle Worldwide staff met weekly to discuss any potential schedule variances and activities which might delay the closing of the project. NABCEP also recruited 46 subject matter experts (SMEs) to work with Castle’s staff on this project. NABCEP staff, SME’s, and Castle staff worked together to develop the Job Task Analyses that form the basis for the certification exams, create new examination forms, conduct passing score studies, and complete a psychometrical analysis of potential exam items. NABCEP’s SMEs utilized Castle’s item development platform during face-to-face meetings, webinars, and remote item authoring to write, review, and approve exam items. Castle also used their software to psychometrically analyze existing exam items to confirm the reliability and validity of the NABCEP’s certification exams. On January 3rd, 2018, NABCEP’s began offering its PV Installation Professional certification exam via CBT. The exam was available at Castle’s nearly 600 exam sites in the United States. A large number of sites will help to ensure better access for solar professionals in rural and remote areas, which drives down the implicit costs of taking the certification exams. Thanks to the STEP grant and the robust partnership between NABCEP and Castle Worldwide, Inc., personnel certifications will be much more accessible and affordable for renewable energy professionals.

14 SOLAR ENERGY↗

DOE OSTI2021

Challenge Solutions for a Significant Water Cut Reduction History Match on Heavy Oil Polymer EOR

Milne Point Field is conducting the first-ever active polymer flood pilot program designed to enhance oil recovery (EOR) of heavy oils on the Alaska North Slope (ANS). The experimental field program consists of two pairs of horizontal injection and production wells deployed in an isolated fault block in the Schrader Bluff reservoir. The EOR method combines polymer flooding and low salinity water flooding to improve recovery. Prior average water cut reduction in polymer EOR fields ordinarily ranges between 10% to 15% for most light oil and heavy oil reservoirs. When comparing other field applications, the long-lasting (24 months) and much lower water cut poses a challenge for numerical history matching when applying typical simulation methods. This abstract discusses two practical new approaches used for history matching of the long-lasting ultralow water cut. These new applications include 1) multiple relative permeability curves with J-function incorporation with low endpoints of relative permeability of water (Krw). This approach integrated the permeability differential adjustment in the geometries of horizontal and vertical directions based on geological review. 2) A specific permeability channel strips along with the horizontal or vertical planar assumption. The current history matching results indicate success in achieving an excellent agreement with the field observed low water-cut.

Namie, S.↗

DOE OSTI2011

Electron-impact study of the S{sub 2} molecule using the R-matrix method

The present study deals with the calculation of elastic [integrated and differential cross section (DCS)], momentum-transfer, excitation, and ionization cross sections for electron impact on S{sub 2} molecules using the R-matrix method. The target states are represented by including correlations via a configuration-interaction technique. We used a double zeta plus polarization Gaussian basis set contracted as (12,8,1)/(6,4,1) for S atoms. The results of the static exchange, correlated one-state, and 20-state close-coupling approximations are presented. We have detected a stable anionic bound state {sup 2}{Pi}{sub g} of S{sub 2}{sup -} having the configuration 1{sigma}{sub g}{sup 2}{center_dot}{center_dot}{center_dot}5{sigma}{sub g}{sup 2} 1{sigma}{sub u}{sup 2}{center_dot}{center_dot}{center_dot}4{sigma}{sub u}{sup 2} 1{pi}{sub u}{sup 4} 1{pi}{sub g}{sup 4} 2{pi}{sub u}{sup 4} 2{pi}{sub g}{sup 3}. The vertical electron affinity value is 1.42 eV, which is comparable with the experimental value of 1.67{+-}0.015 eV. We detected two shape resonances, both of {sup 2}{Pi}{sub u} symmetry in the excitation cross sections of the {sup 1}{Delta}{sub g} and {sup 1}{Sigma}{sub g}{sup +} excited states. The dissociative nature of these resonances is explored by performing scattering calculations in which the S-S bond is stretched. These resonances support dissociative attachment, yielding S and S{sup -}. We have also predicted six resonances of various symmetries ({sup 2}A{sub u}, {sup 2}B{sub 1g},{sup 4}A{sub u}, {sup 4}B{sub 1g}) in the X {sup 3}{Sigma}{sub g}{sup -} {yields} B {sup 3}{Sigma}{sub u}{sup -} transition. We have calculated the DCS, in a correlated one-state model, by using the polydcs program of Sanna and Gianturco. The data from the momentum-transfer cross section, generated from DCS, are used to compute effective collision frequencies over a wide electron temperature range (200-30 000 K). The ionization cross sections are calculated in the binary-encounter Bethe model in which Hartree-Fock molecular orbitals at a self-consistent level are used to calculate kinetic and binding energies of the occupied molecular orbitals. We have included up to g-partial wave (l=4) in the scattering calculations. For this molecule we have used a Born-closure top-up procedure to account for the higher partial waves for the convergence of the cross section for the dipole-allowed excitation from the ground state. We have also evaluated the scattering length of the S{sub 2} molecule, which is equal to 2.615a{sub 0}.

74 ATOMIC AND MOLECULAR PHYSICS↗

DOE OSTI2023

Methodology for physics-informed generation of synthetic neutron time-of-flight measurement data

Accurate neutron cross section data are a vital input to the simulation of nuclear systems for a wide range of applications from energy production to national security. The evaluation of experimental data is a key step in producing accurate cross sections. There is a widely recognized lack of reproducibility in the evaluation process due to its artisanal nature and therefore there is a call for improvement within the nuclear data community. This can be realized by automating/standardizing viable parts of the process, namely, parameter estimation by fitting theoretical models to experimental data. This automation effort could greatly benefit from a synthetic data resource. This work leverages problem-specific physics, Monte Carlo sampling, and a general methodology for data synthesis to generate unlimited, labelled experimental cross-section data that is statistically indistinguishable to the observed data. Heuristic and, where applicable, rigorous statistical comparisons to observed data support this claim. The demonstration is based on/limited to transmission measurements at Rensselaer Polytechnic Institute (RPI) and energy-differential cross sections in the resolved resonance region (RRR). An open-source software is published alongside this article that executes the complete methodology to produce high-utility synthetic datasets. The goal of this work is to provide an approach and corresponding tool that will allow the evaluation community to begin exploring more data-driven, ML-based solutions to long-standing challenges in the field.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

DOE OSTI2020

A new form of the Saint-Venant equations for variable topography

The solution stability of river models using the one-dimensional (1D) Saint-Venant equations can be easily undermined when source terms in the discrete equations do not satisfy the Lipschitz smoothness condition for partial differential equations. Although instability issues have been previously noted, they are typically treated as model implementation issues rather than as underlying problems associated with the form of the governing equations. This study proposes a new reference slope form of the Saint-Venant equations to ensure smooth slope source terms and eliminate one source of potential numerical oscillations. It is shown that a simple algebraic transformation of channel geometry provides a smooth reference slope while preserving the correct cross-section flow area and the total Piezometric pressure gradient that drives the flow. The reference slope method ensures the slope source term in the governing equations is Lipschitz continuous while maintaining all the underlying complexity of the real-world geometry. The validity of the mathematical concept is demonstrated with the open-source Simulation Program for River Networks (SPRNT) model in a series of artificial test cases and a simulation of a small urban creek. Validation comparisons are made with analytical solutions and the Hydrologic Engineering Center's River Analysis System (HEC-RAS) model. The new method reduces numerical oscillations and instabilities without requiring ad hoc smoothing algorithms.

54 ENVIRONMENTAL SCIENCES↗

NASA NTRSDate not supplied

Looking into Ocular Risks of Spaceflight through the Mouse Retina

Ocular alterations have been observed at anatomical levels in astronauts on long duration spaceflight missions, such as what would be required for missions to Mars. These alterations cause an array of signs which together constitute the Spaceflight-Associated Neuro-ocular Syndrome (SANS), one of the top risk priorities of the NASA Human Research Program. Not much is known about SANS at the cellular and molecular level, but studies in mice and rats have recently begun to yield observations on how the spaceflight environment might affect the eye’s biology. Preliminary data from shuttle mouse experiments, and more recently experiments on ISS, have shown changes in retinal physiology via histology and gene expression analysis. This study utilizes samples from the CASIS sponsored Rodent Research 8 Experiment (RRRM-1) tissue sharing opportunity, delivered to the ISS by SpaceX CRS-16 on 12/08/2018. Female BALB/cAnNTac mice were on the ISS for 45 days, while ground controls consisted ofa standard vivarium group and spaceflight habitat group. Here we investigate the molecular response of the mouse retina to identify genes and pathways affected by spaceflight conditions using histology and transcriptomic RNAseq data. This Differentially Expressed Gene (DEG) data was used for pathway analysis with Galaxy (Genelab) and Ingenuity Pathway Analysis (IPA). We identified pathways related to neuronal differentiation, cellular transport/movement, and wound healing. Some of the top DEGs have known relation to ophthalmic diseases. Though there were DEGs throughout the comparisons we tested, there was no clear effect of spaceflight. This could be due to sample processing, which required mice to be returned to Earth about a day before they were sacrificed, possibly allowing for readaptation affecting the retinal transcriptome. However, there was a clear effect of age, between the young (10-12 weeks) and old (32 weeks) groups, and between the baseline and end of experiment, about 46 days.

SANS↗