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At least 1,585 records · Page 88

Protein Crystal Growth Apparatus for Microgravity

Apparatus for growing protein crystals under microgravity environment includes a plurality of protein growth assemblies stacked one above the other within a canister. Each of the protein growth assemblies includes a tray having a number of spaced apart growth chambers recessed below an upper surface. the growth chambers each having an upstanding pedestal and an annular reservoir about the pedestal for receiving a wick and precipitating agents. A well is recessed below the top of each pedestal to define a protein crystal growth receptacle. A flexible membrane is positioned on the upper surface of each tray and a sealing plate is positioned above each membrane, each sealing plate having a number of bumpers corresponding in number and alignment to the pedestals for forcing the membrane selectively against the upper end of the respective pedestal to seal the reservoir and the receptacle when the sealing plate is forced down.

Carter, Daniel C.↗

Microgravity Vibration Control and Civil Applications

Controlling vibration of structures is essential for both space structures as well as terrestrial structures. Due to the ambient acceleration levels anticipated for the International Space Station, active vibration isolation is required to provide a quiescent acceleration environment for many science experiments. An overview is given of systems developed and flight tested in orbit for microgravity vibration isolation. Technology developed for vibration control of flexible space structures may also be applied to control of terrestrial structures such as buildings and bridges subject to wind loading or earthquake excitation. Recent developments in modern robust control for flexible space structures are shown to provide good structural vibration control while maintaining robustness to model uncertainties. Results of a mixed H-2/H-infinity control design are provided for a benchmark problem in structural control for earthquake resistant buildings.

Whorton, Mark Stephen↗

Non-Coalescence Effects in Microgravity

Non-coalescence of two bodies of the same liquid and the suppression of contact between liquid drops and solid surfaces is being studied through a pair of parallel investigations being conducted at the Georgia Institute of Technology and the Microgravity Research and Support (MARS) Center in Naples, Italy. Both non-coalescence and contact suppression are achieved by exploiting the mechanism of thermocapillary convection to drive a lubricating film of surrounding gas (air) into the space between the two liquid free surfaces (non-coalescence) or between the drop free surface and the solid (contact suppression). Earlier experiments performed included flow-visualization experiments in both axisymmetric and (nearly) two-dimensional geometries and quantitative measurements of film thickness in the contact-suppression case in both geometries. Work done in the second year has focused on obtaining quantitative results relating to the effects of variable air pressure, development of analytical and numerical models of non-coalescing droplets and to pursuing potential applications of these self-lubricated systems.

Neitzel, G. Paul↗

Reflight of the First Microgravity Science Laboratory: Quick Turnaround of a Space Shuttle Mission

Due to the short flight of Space Shuttle Columbia, STS-83, in April 1997, NASA chose to refly the same crew, shuttle, and payload on STS-94 in July 1997. This was the first reflight of an entire mission complement. The reflight of the First Microgravity Science Laboratory (MSL-1) on STS-94 required an innovative approach to Space Shuttle payload ground processing. Ground processing time for the Spacelab Module, which served as the laboratory for MSL-1 experiments, was reduced by seventy-five percent. The Spacelab Module is a pressurized facility with avionics and thermal cooling and heating accommodations. Boeing-Huntsville, formerly McDonnell Douglas Aerospace, has been the Spacelab Integration Contractor since 1977. The first Spacelab Module flight was in 1983. An experienced team determined what was required to refurbish the Spacelab Module for reflight. Team members had diverse knowledge, skills, and background. An engineering assessment of subsystems, including mechanical, electrical power distribution, command and data management, and environmental control and life support, was performed. Recommendations for resolution of STS-83 Spacelab in-flight anomalies were provided. Inspections and tests that must be done on critical Spacelab components were identified. This assessment contributed to the successful reflight of MSL-1, the fifteenth Spacelab Module mission.

Simms, Yvonne↗

Pulmonary Deposition of Aerosols in Microgravity

The intrapulmonary deposition of airborne particles (aerosol) in the size range of 0.5 to 5 microns is primarily due to gravitational sedimentation. In the microgravity (muG) environment, sedimentation is no longer active, and thus there should be marked changes in the amount and site of the deposition of these aerosol. We propose to study the total intrapulmonary deposition of aerosol spanning the range 0.5 to 5 microns in the KC-135 at both muG and at 1.8-G. This will be followed by using boli of 1.0 micron aerosol, inhaled at different points in a breath to study aerosol dispersion and deposition as a function of inspired depth. The results of these studies will have application in better understanding of pulmonary diseases related to inhaled particles (pneumoconioses), in studying drugs delivered by inhalation, and in understanding the consequence of long-term exposure to respirable aerosols in long-duration space flight.

Prisk, G. Kim↗

Life and Microgravity Sciences Spacelab Mission: Human Research Pilot Study

The Life Sciences, Microgravity Science and Spacelab Mission contains a number of human experiments directed toward identifying the functional, metabolic and neurological characteristics of muscle weakness and atrophy during space flight. To ensure the successful completion of the flight experiments, a ground-based pilot study, designed to mimic the flight protocols as closely as possible, was carried out in the head-down tilt bed rest model. This report records the rationales, procedures, preliminary results and estimated value of the pilot study, the first of its kind, for 12 of the 13 planned experiments in human research. The bed rest study was conducted in the Human Research Facility at Ames Research Center from July 11 - August 28, 1995. Eight healthy male volunteers performed the experiments before, during and after 17 days bed rest. The immediate purposes of this simulation were to integrate the experiments, provide data in a large enough sample for publication of results, enable investigators to review individual experiments in the framework of a multi-disciplinary study and relay the experience of the pilot study to the mission specialists prior to launch.

Arnaud, Sara B.↗

Effect of Microgravity on Afferent Innervation

Presentations and publications are: (1) an audiovisual summary web presentation on results from SLM-MIR avian experiments. A color presentation summarizing results from the SLM-MIR and STS-29 avian experiments; (2) color threshold and ratio of S 100B MAP5, NF68/200, GABA and GAD; (3) chicken (Gallus domesticus) inner ear afferents; (4) microgravity in the STS-29 Space Shuttle Discovery affected the vestibular system of chick embryos; (5) expression of S 100B in sensory and secretory cells of the vertebrate inner ear; (6) otoconia biogenesis, phylogeny, composition and functional attributes;(7) the glycan keratin sulfate in inner ear crystals; (8) elliptical-P cells in the avian perilymphatic interface of the tegmentum vasculosum; and (9) LAMP2c and S100B upregulation in brain stem after VIIIth nerve deafferentation.

Source record↗

Optimal Controller Design for the Microgravity Isolation Mount (MIM)

H2 controllers, when designed using an appropriate design model and carefully chosen frequency weightings, appear to provide robust performance and robust stability for Microgravity Isolation Mount (MIM). The STS-85 flight data will be used to evaluate the H2 controllers' performance on the actual hardware under working conditions. Next, full-order H-infinity controllers will be developed, as an intermediate step, in order to determine appropriate H-infinity performance weights for use in the mixed-norm design. Finally the basic procedure outlined above will be used to develop fixed-order mixed-norm controllers for MIM.

Hampton, R. David↗

Experiment-to-Experiment Disturbance of Microgravity Environment

The STS-87 Shuttle mission carried the Fourth United States MicroGravity Payload (USMP-4) as one of the primary payloads. Four USMP-4 science experiments were installed on two carriers in the cargo bay of the Shuttle. The Confined Helium Experiment (CHeX), located on the aft carrier, was particularly susceptible to vibrations in several frequency ranges due to structural resonances of the CHeX apparatus and the extreme sensitivity of the sample to vibrations. Shortly after activation of the USMP-4 payload, a strong, vibratory disturbance within the susceptibility region of the CHeX apparatus was detected. After investigating the characteristics of the disturbance and the time at which it first appeared, it was deduced that the vibration was generated by cooling fans in the Isothermal Dendritic Growth Experiment (IDGE). This paper will summarize the development of the conflict, briefly describe the disturbance source, and the susceptibility of the CHeX apparatus, and summarize the results of post-mission tests of IDGE.

DeLombard, Richard↗

Microgravity Processing and Photonic Applications of Organic and Polymeric Materials

In recent years, a great deal of interest has been directed toward the use of organic materials in the development of high-efficiency optoelectronic and photonic devices. There is a myriad of possibilities among organics which allow flexibility in the design of unique structures with a variety of functional groups. The use of nonlinear optical (NLO) organic materials such as thin-film waveguides allows full exploitation of their desirable qualities by permitting long interaction lengths and large susceptibilities allowing modest power input. There are several methods in use to prepare thin films, such as Langmuir-Blodgett (LB) and self-assembly techniques, vapor deposition, growth from sheared solution or melt, and melt growth between glass plates. Organics have many features that make them desirable for use in optical devices such as high second- and third-order nonlinearities, flexibility of molecular design, and damage resistance to optical radiation. However, their use in devices has been hindered by processing difficulties for crystals and thin films. In this chapter, we discuss photonic and optoelectronic applications of a few organic materials and the potential role of microgravity on processing these materials. It is of interest to note how materials with second- and third-order nonlinear optical behavior may be improved in a diffusion-limited environment and ways in which convection may be detrimental to these materials.

Frazier, Donald O.↗

Experiment 3: Zeolite Crystal Growth in Microgravity- The USML-2 Mission

The extensive use of zeolites and their impact on the world's economy leads to many efforts to characterize their structure, and to improve the knowledge base for nucleation and growth of these crystals. The Zeolite Crystal Growth (ZCG) experiment on USML-2 aims to enhance the understanding of nucleation and growth of zeolite crystals while attempting to provide a means of controlling the defect concentration in microgravity. Zeolites A, X, Beta, and Silicalite were grown during the 16-day USML-2 mission. The solutions where the nucleation event was controlled yielded larger and more uniform crystals of better morphology and purity than their terrestrial/control counterparts. Space-grown Beta crystals were free of line defects while terrestrial/controls had substantial defects.

Bac, Nurcan↗

Virtual Reality Simulation of the Effects of Microgravity in Gastrointestinal Physiology

The ultimate goal of this research is to create an anatomically accurate three-dimensional (3D) simulation model of the effects of microgravity in gastrointestinal physiology and to explore the role that such changes may have in the pharmacokinetics of drugs given to the space crews for prevention or therapy. To accomplish this goal the specific aims of this research are: 1) To generate a complete 3-D reconstructions of the human GastroIntestinal (GI) tract of the male and female Visible Humans. 2) To develop and implement time-dependent computer algorithms to simulate the GI motility using the above 3-D reconstruction.

Compadre, Cesar M.↗

The Microgravity Isolation Mount: A Linearized State-Space Model a la Newton and Kane

Vibration acceleration levels on large space platforms exceed the requirements of many space experiments. The Microgravity Vibration Isolation Mount (MIM) was built by the Canadian Space Agency to attenuate these disturbances to acceptable levels, and has been operational on the Russian Space Station Mir since May 1996. It has demonstrated good isolation performance and has supported several materials science experiments. The MIM uses Lorentz (voice-coil) magnetic actuators to levitate and isolate payloads at the individual experiment/sub-experiment (versus rack) level. Payload acceleration, relative position, and relative orientation (Euler-parameter) measurements are fed to a state-space controller. The controller, in turn, determines the actuator currents needed for effective experiment isolation. This paper presents the development of an algebraic, state-space model of the MIM, in a form suitable for optimal controller design. The equations are first derived using Newton's Second Law directly; then a second derivation (i.e., validation) of the same equations is provided, using Kane's approach.

Hampton, R. David↗

A TREETOPS Simulation of the STABLE Microgravity Vibration Isolation System

As a research facility for microgravity science, the International Space Station (ISS) will be used for numerous experiments which require a quiescent acceleration environment across a broad spectrum of frequencies. For many micro-gravity science experiments, the ambient acceleration environment on ISS will significantly exceed desirable levels. The ubiquity of acceleration disturbance sources and the difficulty in characterization of these sources precludes source isolation, requiring, vibration isolation to attenuate the disturbances to an acceptable level at the experiment. To provide a more quiescent acceleration environment, a vibration isolation system named STABLE (Suppression of Transient Accelerations By LEvitation) was developed. STABLE was the first successful flight test of an active isolation device for micro-gravity science payloads and was flown on STS-73/USML-2 in October 1995. This report documents the development of the high fidelity, nonlinear, multibody simulation developed using TREETOPS which was used to design the control laws and define the expected performance of the STABLE isolation system.

Nurre, G. S.↗

Measurement of Critical Contact Angle in a Microgravity Space Experiment

Mathematical theory predicts that small changes in container shape or in contact angle can give rise to large shifts of liquid in a microgravity environment. This phenomenon was investigated in the Interface Configuration Experiment on board the USML-2 Space Shuttle flight. The experiment's "double proboscis" containers were designed to strike a balance between conflicting requirements of sizable volume of liquid shift (for ease of observation) and abruptness of the shift (for accurate determination of critical contact angle). The experimental results support the classical concept of macroscopic contact angle and demonstrate the role of hysteresis in impeding orientation toward equilibrium.

Concus, P.↗

Fundamental Studies of Solidification in Microgravity Using Real-Time X-Ray Microscopy

This research applies a state of the art X-ray Transmission Microscope, XTM, to image (with resolutions up to 3 micrometers) the solidification of metallic or semiconductor alloys in real-time. We have successfully imaged in real-time: interfacial morphologies, phase growth, coalescence, incorporation of phases into the growing interface, and the solute boundary layer in the liquid at the solid-liquid interface. We have also measured true local growth rates and can evaluate segregation structures in the solid; a form of in-situ metallography. During this study, the growth of secondary phase fibers and lamellae from eutectic and monotectic alloys have been imaged during solidification, in real-time, for the first time in bulk metal alloys. Current high resolution X-ray sources and high contrast X-ray detectors have advanced to allow systematic study of solidification dynamics and the resulting microstructure. We have employed a state-of-the-art sub-micron source with acceleration voltages of 10-100 kV to image solidification of metals. One useful strength of the XTM stems from the manner an image is formed. The radiographic image is a shadow formed by x-ray photons that are not absorbed as they pass through the specimen. Composition gradients within the specimen cause variations in absorption of the flux such that the final image represents a spatial integral of composition (or thickness). The ability to image these features in real-time enables more fundamental and detailed understanding of solidification dynamics than has previously been possible. Hence, application of this technique towards microgravity experiments will allow rigorous testing of critical solidification models.

Curreri, Peter A.↗

Utilizing Controlled Vibrations in a Microgravity Environment to Understand and Promote Microstructural Homogeneity During Floating-Zone Crystal Growth

It has been demonstrated in floating-zone configurations utilizing silicone oil and nitrate salts that mechanically induced vibration effectively minimizes detrimental, gravity independent, thermocapillary flow. The processing parameters leading to crystal improvement and aspects of the on-going modeling effort are discussed. Plans for applying the crystal growth technique to commercially relevant materials, e.g., silicon, as well as the value of processing in a microgravity environment are presented.

Grugel, Richard N.↗

Use of Microgravity to Control the Microstructure of Eutectics

The long term goal of this project is to be able to control the microstructure of directionally solidified eutectic alloys, through an improved understanding of the influence of convection. Prior experimental results on the influence of microgravity on the microstructure of fibrous eutectics have been contradictory. Theoretical work at Clarkson University showed that buoyancy-driven convection in the vertical Bridgman configuration is not vigorous enough to alter the concentration field in the melt sufficiently to cause a measurable change in microstructure when the eutectic grows at minimum supercooling. Currently, there are four other hypotheses that might explain the observed changes in microstructure of fibrous eutectics caused by convection: (1) Disturbance of the concentration boundary layer arising from an off-eutectic melt composition and growth at the extremum; (2) Disturbance of the concentration boundary layer of a habit-modifying impurity; (3) Disturbance of the concentration boundary layer arising from an off-eutectic interfacial composition due to non-extremum growth; and (4) A fluctuating freezing rate combined with differences in the kinetics of fiber termination and fiber formation. We favor the last of these hypotheses. Thus, the primary objective of the present grant is to determine experimentally and theoretically the influence of a periodically varying freezing rate on eutectic solidification. A secondary objective is to determine the influence of convection on the microstructure of at least one other eutectic alloy that might be suitable for flight experiments.

Wilcox, William R.↗