Search NASA⌕ Search

SEARCH · Search NASA

Results for “AGE ESTIMATION”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 163 records · Page 9
All sourcesNASA NTRSDOE OSTI
DOE OSTI2011

EXPANSION OF THE YOUNGEST GALACTIC SUPERNOVA REMNANT G1.9+0.3

We present a measurement of the expansion and brightening of G1.9 + 0.3, the youngest Galactic supernova remnant (SNR), comparing Chandra X-ray images obtained in 2007 and 2009. A simple uniform-expansion model describes the data well, giving an expansion rate of 0.642% {+-} 0.049% yr{sup -1} and a flux increase of 1.7% {+-} 1.0% yr{sup -1}. Without deceleration, the remnant age would then be 156 {+-} 11 yr, consistent with earlier results. Since deceleration must have occurred, this age is an upper limit; we estimate an age of about 110 yr or an explosion date of about 1900. The flux increase is comparable to reported increases at radio wavelengths. G1.9+0.3 is the only Galactic SNR increasing in flux, with implications for the physics of electron acceleration in shock waves.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2023

Wildfire smoke exposure and early childhood respiratory health: a study of prescription claims data

Abstract Wildfire smoke is associated with short-term respiratory outcomes including asthma exacerbation in children. As investigations into developmental wildfire smoke exposure on children’s longer-term respiratory health are sparse, we investigated associations between developmental wildfire smoke exposure and first use of respiratory medications. Prescription claims from IBM MarketScan Commercial Claims and Encounters database were linked with wildfire smoke plume data from NASA satellites based on Metropolitan Statistical Area (MSA). A retrospective cohort of live infants (2010–2016) born into MSAs in six western states (U.S.A.), having prescription insurance, and whose birthdate was estimable from claims data was constructed ( N = 184,703); of these, gestational age was estimated for 113,154 infants. The residential MSA, gestational age, and birthdate were used to estimate average weekly smoke exposure days ( smoke-day ) for each developmental period: three trimesters, and two sequential 12-week periods post-birth. Medications treating respiratory tract inflammation were classified using active ingredient and mode of administration into three categories:: 'upper respiratory', 'lower respiratory', 'systemic anti-inflammatory'. To evaluate associations between wildfire smoke exposure and medication usage, Cox models associating smoke-days with first observed prescription of each medication category were adjusted for infant sex, birth-season, and birthyear with a random intercept for MSA. Smoke exposure during postnatal periods was associated with earlier first use of upper respiratory medications (1–12 weeks: hazard ratio (HR) = 1.094 per 1-day increase in average weekly smoke-day, 95%CI: (1.005,1.191); 13–24 weeks: HR = 1.108, 95%CI: (1.016,1.209)). Protective associations were observed during gestational windows for both lower respiratory and systemic anti-inflammatory medications; it is possible that these associations may be a consequence of live-birth bias. These findings suggest wildfire smoke exposure during early postnatal developmental periods impact subsequent early life respiratory health.

Dhingra, Radhika↗
DOE OSTI2012

THE AGE-REDSHIFT RELATION FOR LUMINOUS RED GALAXIES OBTAINED FROM FULL SPECTRUM FITTING AND ITS COSMOLOGICAL IMPLICATIONS

The relative age of galaxies at different redshifts can be used to infer the Hubble parameter and put constraints on cosmological models. We select luminous red galaxies (LRGs) from the Sloan Digital Sky Survey Data Release 7 and then cross match it with the MPA/JHU catalog of galaxies to obtain a large sample of quiescent LRGs at redshift z {approx} 0.03-0.39. The total number of quiescent LRGs, 23,883, is divided into four sub-samples according to their velocity dispersions and each sub-sample is further divided into 12 redshift bins. The spectra of the LRGs in each redshift and velocity bin are co-added in order to obtain a combined spectrum with a relatively high signal-to-noise ratio. Adopting the GalexEV/SteLib model, we estimate the mean ages of the LRGs from these combined spectra by using the full-spectrum fitting method. We check the reliability of the estimated age by using Monte Carlo simulations and find that the estimates are robust and reliable. Assuming that the LRGs in each sub-sample and each redshift bin were on average formed at the same time, the Hubble parameter at the present time H {sub 0} is estimated from the age-redshift relation obtained for each sub-sample, which is compatible with the H {sub 0} value measured by other methods. We demonstrate that a systematic bias (up to {approx}20%) may be introduced to the H {sub 0} estimation because of recent star formation in the LRGs due to the later major mergers at z {approx}< 0.4, but this bias may be negligible for those sub-samples with large velocity dispersions. Using the age-redshift relations obtained from the sub-sample with the largest velocity dispersion or the two sub-samples with high velocity dispersions, we find H {sub 0} = 65{sup +7} {sub -3} km s{sup -1} Mpc{sup -1} or H {sub 0} = 74{sup +5} {sub -4} km s{sup -1} Mpc{sup -1} by assuming a spatially flat {Lambda}CDM cosmology. With upcoming surveys, such as the Baryon Oscillation Spectroscopic Survey, even larger samples of quiescent massive LRGs may be obtained, and thus the Hubble parameter can be measured with high accuracy usimg the age-redshift relation.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2017

The Ages and Masses of a Million Galactic-disk Main-sequence Turnoff and Subgiant Stars from the LAMOST Galactic Spectroscopic Surveys

We present estimates of stellar age and mass for 0.93 million Galactic-disk main-sequence turnoff and subgiant stars from the LAMOST Galactic Spectroscopic Surveys. The ages and masses are determined by matching with stellar isochrones using a Bayesian algorithm, utilizing effective temperature T{sub eff}, absolute magnitude M{sub V}, metallicity [Fe/H], and α-element to iron abundance ratio [α/Fe] deduced from the LAMOST spectra. Extensive examinations suggest the age and mass estimates are robust. Overall, the sample stars have a median error of 34% for the age estimates, and half of the stars older than 2 Gyr have age uncertainties of only 20%–30%. The median error for the mass estimates of the whole sample of stars is ∼8%. The huge data set demonstrates good correlations among stellar age, [Fe/H] ([α/H]), and [α/Fe]. Particularly, double-sequence features are revealed in both the age–[α/Fe] and age–[Fe/H]([α/H]) spaces. In the [Fe/H]–[α/Fe] space, stars of 8–10 Gyr exhibit both the thin and thick disk sequences, while younger (older) stars show only the thin (thick) disk sequence, indicating that the thin disk became prominent 8–10 Gyr ago, while the thick disk formed earlier and was almost quenched 8 Gyr ago. Stellar ages exhibit positive vertical and negative radial gradients across the disk, and the outer disk of R ≳ 9 kpc exhibits a strong flare in stellar age distribution.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2022

Leaf demography spectra, February 2017, PA-SLZ: Panama

This dataset contains leaf reflectance spectra of sunlit canopy leaves from trees at the San Lorenzo Protected Area (PA-SLZ), Panama. Spectra were measured with a full-spectrum (350 -2500 nm) spectroradiometer with a leaf clip attachment. Leaves previously documented in a demography survey were targeted, and each leaf spectrum is paired with species identification, relative leaf position on each branch and estimated leaf age in days. Leaves were measured from the following species: Apeiba membranacea, Carapa guianensis, Guatteria dumetorum, Miconia borealis, Tachigali versicolor, Terminalia amazonia, Tocoyena pittieri and Vochysia ferruginea Unprocessed spectral data are included as SVC *.sig files, and metadata, including sample details, are presented in *.xlsx files. Leaf reflectance spectra of sunlit canopy leaves from trees at the San Lorenzo Protected Area (PA-SLZ), Panama. Spectra were measured with a full-spectrum (350 -2500 nm) spectroradiometer with a leaf clip attachment. Leaves previously documented in a demography survey were targeted, and each leaf spectrum is paired with species identification, relative leaf position on each branch and estimated leaf age in days. Leaves were measured from the following species: Apeiba membranacea, Carapa guianensis, Guatteria dumetorum, Miconia borealis, Tachigali versicolor, Terminalia amazonia, Tocoyena pittieri and Vochysia ferruginea Unprocessed spectral data are included as SVC *.sig files, and metadata, including sample details, are presented in *.xlsx files.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2014

Age gradients in the stellar populations of massive star forming regions based on a new stellar chronometer

A major impediment to understanding star formation in massive star-forming regions (MSFRs) is the absence of a reliable stellar chronometer to unravel their complex star formation histories. We present a new estimation of stellar ages using a new method that employs near-infrared (NIR) and X-ray photometry, Age {sub JX} . Stellar masses are derived from X-ray luminosities using the L{sub X} -M relation from the Taurus cloud. J-band luminosities are compared to mass-dependent pre-main-sequence (PMS) evolutionary models to estimate ages. Age {sub JX} is sensitive to a wide range of evolutionary stages, from disk-bearing stars embedded in a cloud to widely dispersed older PMS stars. The Massive Young Star-Forming Complex Study in Infrared and X-ray (MYStIX) project characterizes 20 OB-dominated MSFRs using X-ray, mid-infrared, and NIR catalogs. The Age {sub JX} method has been applied to 5525 out of 31,784 MYStIX Probable Complex Members. We provide a homogeneous set of median ages for over 100 subclusters in 15 MSFRs; median subcluster ages range between 0.5 Myr and 5 Myr. The important science result is the discovery of age gradients across MYStIX regions. The wide MSFR age distribution appears as spatially segregated structures with different ages. The Age {sub JX} ages are youngest in obscured locations in molecular clouds, intermediate in revealed stellar clusters, and oldest in distributed populations. The NIR color index J – H, a surrogate measure of extinction, can serve as an approximate age predictor for young embedded clusters.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2022

Development of DNA methylation‐based epigenetic age predictors in loblolly pine ( Pinus taeda )

Abstract Biological ageing is connected to life history variation across ecological scales and informs a basic understanding of age‐related declines in organismal function. Altered DNA methylation dynamics are a conserved aspect of biological ageing and have recently been modelled to predict chronological age among vertebrate species. In addition to their utility in estimating individual age, differences between chronological and predicted ages arise due to acceleration or deceleration of epigenetic ageing, and these discrepancies are linked to disease risk and multiple life history traits. Although evidence suggests that patterns of DNA methylation can describe ageing in plants, predictions with epigenetic clocks have yet to be performed. Here, we resolve the DNA methylome across CpG, CHG, and CHH‐methylation contexts in the loblolly pine tree ( Pinus taeda ) and construct epigenetic clocks capable of predicting ages in this species within 6% of its maximum lifespan. Although patterns of CHH‐methylation showed little association with age, both CpG and CHG‐methylation contexts were strongly associated with ageing, largely becoming hypomethylated with age. Among age‐associated loci were those in close proximity to malate dehydrogenase, NADH dehydrogenase, and 18S and 26S ribosomal RNA genes. This study reports one of the first epigenetic clocks in plants and demonstrates the universality of age‐associated DNA methylation dynamics which can inform conservation and management practices, as well as our ecological and evolutionary understanding of biological ageing in plants.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2015

On the absolute age of the metal-rich globular M71 (NGC 6838). I. Optical photometry

We investigated the absolute age of the Galactic globular cluster M71 (NGC 6838) using optical ground-based images (u{sup ′},g{sup ′},r{sup ′},i{sup ′},z{sup ′}) collected with the MegaCam camera at the Canada–France–Hawaii Telescope (CFHT). We performed a robust selection of field and cluster stars by applying a new method based on the 3D (r{sup ′},u{sup ′}−g{sup ′},g{sup ′}−r{sup ′}) color–color–magnitude diagram. A comparison between the color–magnitude diagram (CMD) of the candidate cluster stars and a new set of isochrones at the locus of the main sequence turn-off (MSTO) suggests an absolute age of 12 ± 2 Gyr. The absolute age was also estimated using the difference in magnitude between the MSTO and the so-called main sequence knee, a well-defined bending occurring in the lower main sequence. This feature was originally detected in the near-infrared bands and explained as a consequence of an opacity mechanism (collisionally induced absorption of molecular hydrogen) in the atmosphere of cool low-mass stars. The same feature was also detected in the r′, u{sup ′}−g{sup ′}, and in the r{sup ′},g{sup ′}−r{sup ′} CMD, thus supporting previous theoretical predictions by Borysow et al. The key advantage in using the Δ{sub TO}{sup Knee} as an age diagnostic is that it is independent of uncertainties affecting the distance, the reddening, and the photometric zero point. We found an absolute age of 12 ± 1 Gyr that agrees, within the errors, with similar age estimates, but the uncertainty is on average a factor of two smaller. We also found that the Δ{sub TO}{sup Knee} is more sensitive to the metallicity than the MSTO, but the dependence vanishes when using the difference in color between the MSK and the MSTO.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2021

Raman signatures from age-dating PuO 2 since last calcination

The self-irradiation of PuO 2 has been shown to affect the attributes of fifteen vibrational bands in the Raman spectrum. The vibrational bands correspond to the Raman allowed vibrational mode T 2g , overtones, defects, and bands from electronic origin. Defects in the crystal lattice from low-calcination temperature and alpha decay origins are responsible for the changes in the band attributes (band position, full-width half maximum (FWHM), intensity). Crystal lattice defects are also responsible for the growth of the defect bands. The temporal behavior of the vibrational bands can be used to estimate the age of the material since last calcination. Laser annealing was used to reset the material to full crystallinity prior to the aging study. 240 PuO 2 , with an alpha decay rate of 3.67 greater than the decay rate of 239 PuO 2 , was primarily used to assess the alpha decay-induced damage within 3 years. The aging study focused on the time-dependent properties of the T 2g band and the growth of defect bands. The FWHM of the T 2g band and the ratio of the areas of the defect bands/T 2g band were measured through a time period in excess of 3 years. The data from this study were found very close to the data describing the temporal evolution of the lattice constant measured with the X-ray diffraction (XRD) technique. The local physical properties of the material measured with Raman spectroscopy and the lattice parameter constant measured with XRD indicates a strong correlation between the two techniques. Although both techniques provide similar age-dating information, in contrast to the few milligram quantities required for XRD, Raman spectroscopy requires a 10 µm diameter PuO 2 particle to provide an estimate of the material age since last calcination.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
DOE OSTI2013

Cancer risk estimates from radiation therapy for heterotopic ossification prophylaxis after total hip arthroplasty

Purpose: Heterotopic ossification (HO) is a frequent complication following total hip arthroplasty. This study was conducted to calculate the radiation dose to organs-at-risk and estimate the probability of cancer induction from radiotherapy for HO prophylaxis.Methods: Hip irradiation for HO with a 6 MV photon beam was simulated with the aid of a Monte Carlo model. A realistic humanoid phantom representing an average adult patient was implemented in Monte Carlo environment for dosimetric calculations. The average out-of-field radiation dose to stomach, liver, lung, prostate, bladder, thyroid, breast, uterus, and ovary was calculated. The organ-equivalent-dose to colon, that was partly included within the treatment field, was also determined. Organ dose calculations were carried out using three different field sizes. The dependence of organ doses upon the block insertion into primary beam for shielding colon and prosthesis was investigated. The lifetime attributable risk for cancer development was estimated using organ, age, and gender-specific risk coefficients.Results: For a typical target dose of 7 Gy, organ doses varied from 1.0 to 741.1 mGy by the field dimensions and organ location relative to the field edge. Blocked field irradiations resulted in a dose range of 1.4–146.3 mGy. The most probable detriment from open field treatment of male patients was colon cancer with a high risk of 564.3 × 10{sup −5} to 837.4 × 10{sup −5} depending upon the organ dose magnitude and the patient's age. The corresponding colon cancer risk for female patients was (372.2–541.0) × 10{sup −5}. The probability of bladder cancer development was more than 113.7 × 10{sup −5} and 110.3 × 10{sup −5} for males and females, respectively. The cancer risk range to other individual organs was reduced to (0.003–68.5) × 10{sup −5}.Conclusions: The risk for cancer induction from radiation therapy for HO prophylaxis after total hip arthroplasty varies considerably by the treatment parameters, organ site in respect to treatment volume and patient's gender and age. The presented risk estimates may be useful in the follow-up studies of irradiated patients.

61 RADIATION PROTECTION AND DOSIMETRY↗
DOE OSTI2019

On the Mass Accretion Rate and Infrared Excess in Herbig Ae/Be Stars

The present study makes use of the unprecedented capability of the Gaia mission to obtain the stellar parameters such as distance, age, and mass of HAeBe stars. The accuracy of Gaia DR2 astrometry is demonstrated from the comparison of the Gaia DR2 distances of 131 HAeBe stars with the previously estimated values from the literature. This is one of the initial studies to estimate the age and mass of a confirmed sample of HAeBe stars using both the photometry and distance from the Gaia mission. Mass accretion rates are calculated from Hα line flux measurements of 106 HAeBe stars. Since we used distances and the stellar masses derived from the Gaia DR2 data in the calculation of the mass accretion rate, our estimates are more accurate than previous studies. The mass accretion rate is found to decay exponentially with age, from which we estimated a disk dissipation timescale of 1.9 ± 0.1 Myr. The mass accretion rate and stellar mass exhibit a power-law relation of the form M-dot {sub acc}∝M{sub ∗}{sup 2.8±0.2}. From the distinct distribution in the values of the infrared spectral index, n{sub 2--4.6}, we suggest the possibility of difference in the disk structure between Herbig Be and Herbig Ae stars.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2014

Intermediate-age globular clusters in four galaxy merger remnants

We present the results of combining Hubble Space Telescope optical photometry with ground-based K{sub s} -band photometry from the Gemini imagers NIRI and FLAMINGOS-I to study the globular cluster (GC) populations in four early-type galaxies that are candidate remnants of recent mergers (NGC 1700, NGC 2865, NGC 4382, and NGC 7727). These galaxies were chosen based on their blue colors and fine structure, such as shells and ripples that are indicative of past interactions. We fit the combined VIK{sub s} GC data with simple toy models of mixed cluster populations that contain three subpopulations of different age and metallicity. The fits, done via chi-squared mapping of the parameter space, yield clear evidence for the presence of intermediate-age clusters in each galaxy. We find that the ages of ∼1-2 Gyr for these GC subpopulations are consistent with the previously estimated merger ages for the host galaxies.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2018

Recent seawater intrusion into deep aquifer determined by the radioactive noble-gas isotopes 81 Kr and 39 Ar

Radioactive noble-gas isotopes tracers 81 Kr and 39 Ar are used for the first time to measure the residence times of deep (~1000 m) saline coastal groundwater, and to determine its connection mode with the sea. The average rate of seawater intrusion into the deep aquifer in Israel, located near the Mediterranean Sea, is estimated. 81 Kr-ages of the saline water samples, found to be younger than 40 ka, contradict previously estimated ages of up to several million years based on hydrogeological considerations. The new results imply a stronger and more recent connection between the aquifer and the sea, and indicate that the intrusion occurred during the sea-level rise that began about 20 ka ago. These coastal aquifers need to be managed with caution because lowering of the adjacent fresh water level due to over pumping could accelerate seawater intrusion in a relatively short time. As a result, this study demonstrates the suitability of these two noble-gas tracers for the examination of hydrogeological systems in general and for the study of seawater intrusion in particular.

39Ar↗
DOE OSTI2019

Spatial variations in the Milky Way disc metallicity–age relation

ABSTRACT Stellar ages are a crucial component to studying the evolution of the Milky Way. Using Gaia DR2 distance estimates, it is now possible to estimate stellar ages for a larger volume of evolved stars through isochrone matching. This work presents [M/H]–age and [α/M]–age relations derived for different spatial locations in the Milky Way disc. These relations are derived by hierarchically modelling the star formation history of stars within a given chemical abundance bin. For the first time, we directly observe that significant variation is apparent in the [M/H]–age relation as a function of both Galactocentric radius and distance from the disc mid-plane. The [M/H]–age relations support claims that radial migration has a significant effect in the plane of the disc. Using the [M/H] bin with the youngest mean age at each radial zone in the plane of the disc, the present-day metallicity gradient is measured to be −0.059 ± 0.010 dex kpc−1, in agreement with Cepheids and young field stars. We find a vertically flared distribution of young stars in the outer disc, confirming predictions of models and previous observations. The mean age of the [M/H]–[α/M] distribution of the solar neighbourhood suggests that the high-[M/H] stars are not an evolutionary extension of the low-α sequence. Our observational results are important constraints to Galactic simulations and models of chemical evolution.

Feuillet, Diane K.↗
DOE OSTI2016

Regional oxygen reduction and denitrification rates in groundwater from multi-model residence time distributions, San Joaquin Valley, USA

Rates of oxygen and nitrate reduction are key factors in determining the chemical evolution of groundwater. Little is known about how these rates vary and covary in regional groundwater settings, as few studies have focused on regional datasets with multiple tracers and methods of analysis that account for effects of mixed residence times on apparent reaction rates. This study provides insight into the characteristics of residence times and rates of O 2 reduction and denitrification (NO 3 – reduction) by comparing reaction rates using multi-model analytical residence time distributions (RTDs) applied to a data set of atmospheric tracers of groundwater age and geochemical data from 141 well samples in the Central Eastern San Joaquin Valley, CA. The RTD approach accounts for mixtures of residence times in a single sample to provide estimates of in-situ rates. Tracers included SF 6 , CFCs, 3 H, He from 3 H (tritiogenic He), 14 C, and terrigenic He. Parameter estimation and multi-model averaging were used to establish RTDs with lower error variances than those produced by individual RTD models. The set of multi-model RTDs was used in combination with NO 3 – and dissolved gas data to estimate zero order and first order rates of O 2 reduction and denitrification. Results indicated that O 2 reduction and denitrification rates followed approximately log-normal distributions. Rates of O 2 and NO 3 – reduction were correlated and, on an electron milliequivalent basis, denitrification rates tended to exceed O 2 reduction rates. Estimated historical NO 3 – trends were similar to historical measurements. Here, results show that the multi-model approach can improve estimation of age distributions, and that relatively easily measured O 2 rates can provide information about trends in denitrification rates, which are more difficult to estimate.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2018

Phylogenomics of Endogonaceae and evolution of mycorrhizas within Mucoromycota

Endogonales (Mucoromycotina), composed of Endogonaceae and Densosporaceae, is the single known non-Dikarya order with ectomycorrhizal members. Furthermore, they form mycorrhizal-like association with some nonspermatophyte plants. It has been recently proposed that Endogonales were among the earliest mycorrhizal partners with land plants. It remains unknown whether Endogonales possess genomes with mycorrhizal-lifestyle signatures and whether Endogonales originated around the same time as land plants did. We sampled sporocarp tissue from four Endogonaceae collections and performed shotgun genome sequencing. After binning the metagenome data, we assembled and annotated the Endogonaceae genomes. We performed comparative analysis on plant-cell-wall-degrading enzymes (PCWDEs) and small secreted proteins (SSPs). We inferred phylogenetic placement of Endogonaceae and estimated the ages of Endogonaceae and Endogonales with expanded taxon sampling. Endogonaceae have large genomes with high repeat content, low diversity of PCWDEs, but without elevated SSP/secretome ratios. Dating analysis estimated that Endogonaceae originated in the Permian–Triassic boundary and Endogonales originated in the mid–late Silurian. Mycoplasma-related endobacterium sequences were identified in three Endogonaceae genomes. Endogonaceae genomes possess typical signatures of mycorrhizal lifestyle. The early origin of Endogonales suggests that the mycorrhizal association between Endogonales and plants might have played an important role during the colonization of land by plants.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2025

DNA methylation–based age prediction and sex-specific epigenetic aging in a lizard with female-biased longevity

Sex differences in life span are widespread across animal taxa, but their causes remain unresolved. Alterations to the epigenome are hypothesized to contribute to vertebrate aging, and DNA methylation–based aging clocks allow for quantitative estimation of biological aging trajectories. Here, we investigate the influence of age, sex, and their interaction on genome-wide DNA methylation patterns in the brown anole (Anolis sagrei), a lizard with pronounced female-biased survival and longevity. We develop a series of age predictor models and find that, contrary to our predictions, rates of epigenetic aging were not slower in female lizards. However, methylation states at loci acquiring age-associated changes appear to be more “youthful” in young females, suggesting that female DNA methylomes are preemptively fortified in early life in opposition to the direction of age-related drift. Collectively, our findings provide insights into epigenetic aging in reptiles and suggest that early-life epigenetic profiles may be more informative than rates of change for predicting sex biases in longevity.

59 BASIC BIOLOGICAL SCIENCES↗