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NASA NTRSDate not supplied

B Complex 5-Methyltetrahydrofolate, Riboflavin, Pyridoxine, and Methylcobalamin Supplementation as a Non-Mechanical Countermeasure to Mitigate Optic Disc Edema Changes During Strict 6º Head-Down Tilt Bed Rest

A subset of astronauts on International Space Station missions have experienced optic disc edema, part of what is characterized as Spaceflight Associated Neuro-ocular Syndrome (SANS). While the precise cause of SANS is unknown, it is likely that there are multiple contributing factors, including genetic and environmental factors. Our recent work has shown that crewmembers with SANS have higher concentrations of metabolic biomarkers of impairments in the one-carbon metabolic pathway compared to unaffected astronauts - before, during, and after f light (1). B-vitamin status and the presence of one-carbon pathway single nucleotide polymorphism (SNP) variants predicted the incidence of SANS pathologies, including optic disc edema (2). Specifically, the G allele of methionine synthase reductase (MTRR) A66G and the C allele of serine hydroxymethyltransferase-1 (SHMT1) C1420T were associated with increased incidence of SANS pathologies (2). In a recent 30-d bed rest head-down tilt study with 0.5% CO2 exposure, 5 of 11 subjects developed optic disc edema (4) and the same SHMT1 C1420T and MTRR A66G genetic variants were associated with a larger increase in total retina thickness, a quantitative measure of optic disc edema (5). We published a multi-hit hypothesis of how genetics represents an indispensable element of SANS, which is a multifactorial problem (6). In brief: endothelial dysfunction secondary to genetic, biochemical/nutritional, and physiological (e.g., cardiovascular/fluid shift) f actors could lead to optic disc edema and the other ocular changes that occur in SANS. We expanded this hypothesis to include the possibility that genetic effects on B-vitamin status can alter nitric oxide synthesis and oxidative stress in the endothelium. This in turn could alter the turnover of structural components of the sclera, making it more susceptible to pathologic changes when faced with stressors related to the unrelenting headward fluid shift that occurs in weightlessness and strict head-down tilt bed rest (5). If the relationships that we have observed in flight and ground-based research hold true for the SANS Countermeasure Study, these genetic factors could predict who will be more susceptible to the development of SANS, and more importantly could also provide countermeasure options. As has been shown extensively in the literature, vitamin supplementation can serve to overcome genetic hindrances to one-carbon biochemistry and vascular physiology. Thus, based on our findings, publications, and hypotheses, supported by extensive supporting literature, we had hoped to test in the SANS Countermeasure Study the efficacy of a bioactive B-vitamin complex as a countermeasure to optimize function of the one-carbon pathway and prevent or mitigate optic disc edema during strict 6-degree head down tilt bed rest, and ultimately in space f light. While the supplement is no longer planned to be tested in the SANS Countermeasure Study because of laws regulating supplementation studies like this costing much more than initially planned, we will assess the contribution of one-carbon pathway genetics and B-vitamin status to SANS risk.

S R Zwart↗
NASA NTRS2021

Context and future directions for integrating forest carbon into sub-national climate mitigation planning in the RGGI region of the U.S.

International frameworks for climate mitigation that build from national actions have been developed under the United National Framework Convention on Climate Change and advanced most recently through the Paris Climate Agreement. In parallel, sub-national actors have set greenhouse gas (GHG) reduction goals and developed corresponding climate mitigation plans. Within the U.S., multi-state coalitions have formed to facilitate coordination of related science and policy. Here, utilizing the forum of the NASA Carbon Monitoring System’s Multi-State Working Group, we collected and reviewed climate mitigation plans for 11 states in the Regional Greenhouse Gas Initiative region of the Eastern U.S. For each state we reviewed the (a) policy framework for climate mitigation, (b) GHG reduction goals, (c) inclusion of forest activities in the state’s climate action plan, (d) existing science used to quantify forest carbon estimates, and (e) stated needs for forest carbon monitoring science. Across the region, we found important differences across all categories. While all states have GHG reduction goals and framework documents, nearly three-quarters of all states do not account for forest carbon when planning GHG reductions; those that do account for forest carbon use a variety of scientific methods with various levels of planning detail and guidance. We suggest that a common, efficient, standardized forest carbon monitoring system would provide important benefits to states and the geographic region as a whole. In addition, such a system would allow for more effective transparency and progress tracking to support state, national, and international efforts to increase ambition and implementation of climate goals.

Rachel L Lamb↗
NASA NTRS2021

Uneven Consequences: Gendered Impacts of Shrimp Aquaculture Development on Mangrove Dependent Communities

Shrimp aquaculture is a primary driver of mangrove deforestation globally. The decline of these forests not only threatens the integrity of valuable ecosystems but can also produce detrimental impacts on mangrove-dependent communities. Ecuador is the largest producer of farmed Pacific white leg shrimp (Litopenaeus vannamei) in South America. This industry’s growth and success have come at the expense of the country’s mangrove forests. This paper analyzes the impacts of shrimp aquaculture development on a mangrove-dependent community in Esmeraldas province, Ecuador. Furthermore, this research highlights how gender and gendered norms inform the strategies adopted by different actors in response to these processes. Drawing from ethnographic and Global Positioning System data collected in situ, this study shows that women are disproportionately affected by the loss of mangrove forests. Mangrove forests have historically provided women sustenance, opportunities for income generation, and the ability to pass on cultural traditions. The establishment of the aquaculture sector also created a collapse of local livelihoods. Losing access to traditional livelihood practices pushed men into the mangroves to gather cockles, a productive activity customarily only practiced by women. This livelihood shift for men further contributes to the displacement of women from the mangrove forests. The introduction of industrial shrimp farming increased the community’s reliance on mangrove resources. The overuse of these resources is leading to a depletion of mangrove cockle populations, putting the community in a vulnerable position as both men and women are increasingly dependent on this fishery to subsist.

Gender Mangrove fisheries↗
NASA NTRS2021

INTEGRAL reloaded: Spacecraft, instruments and ground system

The European Space Agency’s INTErnational Gamma-Ray Astrophysics Laboratory (ESA/INTEGRAL) was launched aboard a Proton-DM2 rocket on 17 October 2002 at 06:41 CEST, from Baikonur in Kazakhstan. Since then, INTEGRAL has been providing long, uninterrupted observations (up to about 47 h, or 170 ksec, per satellite orbit of 2.7 days) with a large field-of-view (FOV, fully coded: 100 deg), millisecond time resolution, keV energy resolution, polarization measurements, as well as additional wavelength coverage at optical wavelengths. This is realized by two main instruments in the 15 keV to 10 MeV energy range, the spectrometer SPI (spectral resolution 3 keV at 1.8 MeV) and the imager IBIS (angular resolution: 12 arcmin FWHM), complemented by X-ray (JEM-X; 3–35 keV) and optical (OMC; Johnson V-band) monitor instruments. All instruments are co-aligned to simultaneously observe the target region. A particle radiation monitor (IREM) measures charged particle fluxes near the spacecraft. The Anti-coincidence subsystems of the main instruments, built to reduce the background, are also very efficient all-sky γ-ray detectors, which provide virtually omni-directional monitoring above ~75 keV. Besides the long, scheduled observations, INTEGRAL can rapidly (within a couple of hours) re-point and conduct Target of Opportunity (ToO) observations on a large variety of sources. INTEGRAL observations and their scientific results have been building an impressive legacy: The discovery of currently more than 600 new high-energy sources; the first-ever direct detection of (56)Ni and (56)Co radio-active decay lines from a Type Ia supernova; spectroscopy of isotopes from galactic nucleo-synthesis sources; new insights on enigmatic positron annihilation in the Galactic bulge and disk; and pioneering gamma-ray polarization studies. INTEGRAL is also a successful actor in the new multi-messenger astronomy introduced by non-electromagnetic signals from gravitational waves and from neutrinos: INTEGRAL found the first prompt electromagnetic radiation in coincidence with a binary neutron star merger. Up to now more than 1750 scientific papers based on INTEGRAL data have been published in refereed journals. In this paper, we will give a comprehensive update of the satellite status after more than 18 years of operations in a harsh space environment, and an account of the successful Ground Segment.

Erik Kuulkers↗
NASA NTRS2022

Lunar Landing and Operations Policy Analysis

Just within the next four years, we expect to see at least 22 lunar surface missions. Half of these missions will occur in the Moon’s south polar region. Due to this upcoming proliferation of actors and activities at or near the lunar south pole, and due to the potential close proximity of operations, NASA and other operators will face challenges never faced before. NASA’s Deputy Administrator and Associate Administrator of the Science Mission Directorate (SMD) tasked the Office of Technology, Policy, and Strategy (OTPS) with answering two questions related to the Artemis campaign: (1) what technical and policy considerations should NASA take into account in the selection of lunar landing and operations sites, and (2) what technical and policy considerations should NASA take into account when implementing tools such as safety zones in order to protect these operations and U.S. interests? In addition to the challenges inherent in lunar operations, NASA subject-matter experts (SMEs) are concerned about certain challenges to NASA operations that may require policy solutions. The goal of this report is to provide options and recommendations to NASA leadership and program planners so that they can consider policy measures to respond to those challenges. This report also describes options for transparency, coordination, and implementation to increase the effectiveness of these measures.

lunar policy↗
NASA NTRS2023

Lunar Landing and Operations Policy Analysis

At least 22 lunar missions are planned in the next four years. Half of these missions will occur in the Moon’s south polar region. Due to this upcoming proliferation of actors and activities at or near the lunar south pole, and due to the potential close proximity of operations, NASA and other operators will face challenges never faced before. NASA’s Deputy Administrator and Associate Administrator of the Science Mission Directorate tasked the Office of Technology, Policy, and Strategy with answering two questions related to the Artemis campaign: (1) what technical and policy considerations should NASA take into account in the selection of lunar landing and operations sites, and (2) what technical and policy considerations should NASA take into account when implementing tools such as safety zones in order to protect these operations and U.S. interests? We present policy tools (options and recommendations) to NASA leadership and program planners so that they can consider policy measures to respond to challenges inherent in landing and operating at the lunar South Pole—this answers question one. We also describe a set of options (transparency, coordination, and implementation) to increase the effectiveness of these tools—this answers question two.

Lunar policy↗
NASA NTRSDate not supplied

NASA Best Practices Overview

While prevention of launch and on-orbit collisions has been an institutional concern of NASA for several decades (beginning with the Shuttle program), historically the paucity of space actors and deployed payloads made the conduct of such protection activities relatively straightforward. With the substantial increases in launched payloads over the last several years, collision avoidance operations have become substantially more complicated. At the same time, many operators are uncertain regarding what collision avoidance activities are appropriate to their missions. The lack of a space traffic management authority to articulate standards and guidelines for such conduct has only increased the confusion. In response to this situation, NASA has published a Spacecraft Conjunction Assessment and Collision Avoidance Handbook, which articulates and explains the launch and on-orbit collision avoidance best practices that the Agency has developed and is requiring of present and future NASA missions. Because the CA2 Handbook is a living document regularly updated to reflect best practices changes as the industry develops, feedback from both NASA missions and other users is continuously collected in order to issue CA2 Handbook updates. This talk will summarize and explain the collision avoidance best practices from the CA2 Handbook, along with the key issues that drove the selection of those practices.

Conjunction Assessment↗
NASA NTRSDate not supplied

Airspace Integration Considerations for Increasingly Autonomous Flight and Operations

There is much interest in autonomous systems and their operations. When it comes to autonomous systems, it is critical to understand various levels of proposed autonomy, reasons for selecting autonomous capabilities, certification approaches and various challenges or research needs associated with the integration of autonomous systems in the National Airspace System (NAS). Furthermore, there are levels of autonomous systems proposed for different types of aircraft including: single pilot operations, remotely piloted operations, fully autonomous operations, and multiple aircraft managed by a single, remote pilot. This preliminary article aims to provide a broad overview rather than concentrate on a specific element of autonomous flight. Hence, the focus of this article is on enabling various types of increasingly autonomous aircraft and their operations routinely within the next five to ten years, consistent with the FAA’s Info-Centric NAS (ICN) vision. Under ICN, a fully integrated information environment supports collaboration across diverse traffic management services and shifts decision-making to the most appropriate actor supported by automation. However, the roles and responsibilities of Air Traffic Services (ATS) personnel providing traditional services are likely to be very similar to today in that humans will still be responsible for majority of decision making. There is another NASA research effort beyond ICN is underway called Sky For All which is not covered in this article as it is in the planning stages.

autonomy↗
NASA NTRS2023

Missed Approach Procedures in Advanced Air Mobility: Conceptual Exploration

The High Density Vertiplex Sub-Project, as part of NASA’s Advanced Air Mobility (AAM) Project, has been in collaboration with a team from Wisk Aero focusing on vertiport operations, procedures, and concept development. A particular area of focus has been on the development of missed approach scenarios and procedures that highlight the potential changes in the nearer- and further-term operational time frames. Such changes relate to topic areas such as airspace design, automation and autonomy, roles and responsibilities of actors and stakeholders, airspace management services and systems, as well as technologies specific to vertiport operations management. This paper presents the current state of joint concept development through the established collaboration and the application of elements in ongoing testing as part of NASA’s High Density Vertiplex Sub-Project’s research strategy.

vertiport↗
NASA NTRS2024

CLIMATE CHANGE 2023 Synthesis Report Summary for Policymakers

This Synthesis Report (SYR) of the IPCC Sixth Assessment Report (AR6) summarises the state of knowledge of climate change, its widespread impacts and risks, and climate change mitigation and adaptation. It integrates the main findings of the Sixth Assessment Report (AR6) based on contributions from the three Working Groups, and the three Special Reports. The summary for Policymakers (SPM) is structured in three parts: SPM.A Current Status and Trends, SPM.B Future Climate Change, Risks, and Long-Term Responses, and SPM.C Responses in the Near Term. This report recognizes the interdependence of climate, ecosystems and biodiversity, and human societies; the value of diverse forms of knowledge; and the close linkages between climate change adaptation, mitigation, ecosystem health, human well-being and sustainable development, and reflects the increasing diversity of actors involved in climate action. Based on scientific understanding, key findings can be formulated as statements of fact or associated with an assessed level of confidence using the IPCC calibrated languages.

climate impacts↗
NASA NTRSDate not supplied

Missed Approach Procedures in Advanced Air Mobility: Conceptual Exploration

The High Density Vertiplex Sub-Project, as part of NASA’s Advanced Air Mobility (AAM) Project, has been in collaboration with a team from Wisk Aero focusing on vertiport operations, procedures, and concept development. A particular area of focus has been on the development of missed approach scenarios and procedures that highlight the potential changes in the nearer- and further-term operational time frames. Such changes relate to topic areas such as airspace design, automation and autonomy, roles and responsibilities of actors and stakeholders, airspace management services and systems, as well as technologies specific to vertiport operations management. This presentation encompasses the content of the associated paper that presents the current state of joint concept development through the established collaboration and the application of elements in ongoing testing as part of NASA’s High Density Vertiplex Sub-Project’s research strategy.

vertiport↗
NASA NTRSDate not supplied

Near-Term Policy Considerations for Lunar Missions

Near-Term Policy Considerations for Lunar Missions. Therese Jones1, Gabriel Swiney,1 and Katie McBrayer,2 1NASA HQ, 300 Hidden Figures Way SW, Washington, D.C. 20546, 2NASA Langley Re-search Center, 1 NASA Drive, Hampton, VA, 23666. (Contact: therese.m.jones@nasa.gov) Introduction: More than two dozen lunar missions are planned prior to the Artemis III crewed lunar landing, from Russian, Chinese, Indian, Japanese and U.S. government orbiters and landers to Commercial Lunar Payload Ser-vices missions to commercial crewed flybys. While the Artemis Accords have established an international consortium of countries seeking to mitigate interference between operations on the Moon, a number of unaddressed policy issues remain that may be critical to lunar operations. In this lightning talk, we build upon NASA’s Of-fice of Technology, Policy, and Strategy’s Sep-tember 2022 Report “Lunar Landing and Oper-ations Policy Analysis” [1], to give an overview of policy questions that remain open, including: whether to prioritize certain landing locations or avoid certain scientifically valuable locations, design and coordination of safety zones, notifi-cation of other actors of potential dangers posed by landing, whether to avoid placing equipment in operationally valuable locations, and end-of-life disposal. We will also discuss how these policy implications could apply to planned missions.. References: [1] Swiney, G., and Hernandez, A. Lunar Landing and Operations Policy Analy-sis, NASA Office of Technology, Policy, and Strategy, September 30, 2022 https://www.nasa.gov/sites/default/files/atoms/files/nasa-otps-lunar-landing-and-operations-policy-analysis-final-report_2.pdf

Therese Jones↗
NASA NTRS2023

Artemis, Ethics and Society: Synthesis from a Workshop

NASA’s planning and implementation of the Artemis missions and Moon to Mars efforts may set precedents in exploration for decades to come. In April 2023, NASA convened a workshop on how to assess the ethical and societal implications of Artemis. This workshop was NASA’s first structured foray into studying the ethical and societal implications of exploration since the Apollo program in the 1960s. This report documents the discussion and ideas feedback and suggestions from the 55 participants invited to the Artemis and Ethics workshop and focuses on the following key study questions: 1) How should NASA consider the ethical, legal, and societal implications (ELSI) of the Artemis and Moon to Mars efforts?; and 2) What are the key ethical and societal implications that need consideration? This initial exploratory study does not make formal recommendations but instead maps out options available for NASA and other actors to consider as humanity goes to the Moon, Mars and beyond.

Artemis↗
NASA NTRS2021

NOAA-17 Break-up Engineering Investigation Board Final Report

The NOAA-17 break-up was found to be a single, localized debris event producing about100 trackable pieces; there is likely no catastrophic damage to the whole spacecraft. NOAA-17 debris is very much in family with NOAA-16 debris, and DMSP F11 and F13 are very much in family with each other and share similarities with NOAA-16 and 17; it is likely all four (“The Big Four”) share the same debris source. DMSP F13 break-up occurred simultaneous with a known battery overcharge and therefore battery rupture is most likely intermediate cause of the Big Four break-ups; this is a low confidence assessment since other debris sources cannot be definitively ruled out. No root cause was found as the NOAA-17 batteries were all confirmed to have been disconnected from the charge path as intended. Possible conditions for reconnection are all unlikely including short circuits and commanding from a “bad actor.” All related spacecraft pose a risk of similar break-ups for decades to come and are a threat to the critical 800-850 km polar orbit regime; even appropriately decommissioned spacecraft appear to be at risk. Recommendations include an update to the decommissioning procedure and consideration of further investigations and active debris removal, consistent with national policy.

Maggie Atkinson↗
NASA NTRSDate not supplied

Development and Implementation of A Small Satellite Systems Engineering Webinar Series: A Collaboration Between the United Nations Office for Outer Space Affairs and the National Aeronautics and Space Administration

The United Nations Office for Outer Space Affairs (UNOOSA) in collaboration with the National Aeronautics and Space Administration (NASA) established a webinar series on NASA systems engineering standards and practices for the purpose of sharing knowledge in this area. UNOOSA’s “Access to Space for All” initiative provides capacity-building opportunities in space science, technology, and space applications for United Nations member states. Due to the cooperation among established space actors, the United Nations, and emerging space entities, the initiative enables students from developing countries from all over the world to carry out projects using technologies and space applications. Through NASA’s Small Spacecraft Systems Virtual Institute (S3VI), the four-part webinar series was designed to cover basic systems engineering and project management skills that are fundamental to planning, developing, and implementing an experiment or a space project and that serve as critical knowledge for those engaged in space activities, whether as a designer, builder, or manager of space infrastructure and services. The first series of webinars was convened over the course of November 2023 through February 2024.

Systems Engineering↗
NASA NTRS2024

Cooperative and Non-Cooperative UAS Detection

This paper describes a system that enhances airspace situational awareness by detecting and identifying Unmanned Aerial Systems (UAS). This multi-domain solution tracks both cooperative scientific flights as well as non-cooperative intrusions from "bad actors." The system supports a critical push towards safety within NASA’s advanced air mobility mission. After surveying the existing technologies at Langley Research Center, the radar and visual systems were chosen for the primary and secondary detection mechanisms, respectively. These systems were tuned an upgraded to become more sensitive to UAS activity. Additionally, a Remote Identification receiver was procured and integrated into the flight surveillance system.

Lucas Barduson↗
NASA NTRS2024

DSS Security Assessment

The Discovery and Synchronization service (DSS) has implemented some reasonable technical controls that help improve security and there are very few technical findings. The use of Docker and Kubernetes helps simplify the deployment process, and the DSS uses mutual TLS (mTLS) to connect. Much of the security risk across the DSS is a factor of its nature, a distributed environment that relies on all members to secure their parts correctly. As such, the DSS team should attempt to emphasize security controls that reduce complexity for securing entities’ Cockroach DB (CRDB) instances properly and improve coordination among DSS members for things like security patching, incident response, detecting, and removing bad actors. The DSS team must recognize that operating a DSS instance securely will require a combination of technical and procedural controls. Each DSS entity must configure their instance properly and follow standard operating procedures to ensure that the DSS service is secure.

threat modeling↗
NASA NTRSDate not supplied

System Modeling of a Lunar Molten Regolith Electrolysis Plant

Introduction: In-Situ Resource Utilization (ISRU) is the process of extracting local resources to produce commodities for propulsion, life support systems, and off-planet construction rather than transporting consumables from Earth. Molten Regolith Electrolysis (MRE) is a novel ISRU method of extracting oxygen gas and metal alloy from lunar regolith. The MRE process involves placing lunar regolith between two electrodes, through which current is passed, to melt the regolith and reduce the metal oxide constituents by direct electrolysis (e.g. FeO, SiO2, MgO, Al2O3) into oxygen gas and metal alloys. The oxygen is liquefied and used as propellant for landers, while the metals (e.g. Ferro-alloys) are further processed and used in structural building materials and parts manufacturing. A system model was developed that accounted for the major processes of an MRE plant (from excavation of raw materials to storage of products) to assess the feasibility of a lunar MRE plant. The System Engineering and Integration (SE&I) ISRU Modeling and Analysis (SIMA) team utilized its previously documented system sizing model, the Mission Analysis and Integration Tool (MAIT) [1] as framework of the system model. MAIT uses MATLAB/Simulink to integrate subsystem models into a complete system model of the MRE plant. Total mass, volume, and power requirements were computed for numerous iterations of a MRE plant. System Model: Figure 1: MRE Plant Block Diagram The regolith excavation model determines the mass and power needed to excavate sufficient regolith. The preheating auger initiates the regolith heating process before regolith enters the MRE re-actor to reduce the energy required to turn the solid into a molten liquid. The MRE reactor is modeled in COMSOL Multiphysics and based on the research by Dominguez, Sibille, and Schreiner [2, 3, 4]. This preliminary reactor model provides an accurate calculation of thermal equilibrium during electrochemical operation of the reactor system to assess the optimal mass and power required to process the inlet flow of regolith. The model also computes the outlet flowrates of oxygen and molten products. For this analysis, the primary components of the metal alloy considered were iron and silicon. The oxygen is then purified using an Yttrium Stabilized Zirconia (YSZ) electrode, followed by liquefaction using a 90K cryocooler to be stored as liquid oxygen in insulated cylindrical tanks. In future iterations of the system model, the molten metal tapped from the MRE reactor will undergo additional processing or refinement. However, downstream handling of metals is currently a technology gap that is missing a high TRL subsystem model. Therefore, for this analysis, the accumulated metal alloy stream terminates after leaving the MRE reactor. Study Goals: This analysis investigates multiple input variables to the system to determine the sensitivity of a (near) complete plant at full-scale. This preliminary investigation ran parametric sweeps on the MRE reactor geometry, electrical current supply, layers of multi-layer insulation (MLI) on the reactor, size of the electrodes in the oxygen purification model, and regolith composition (based on landing site location). Three production targets of oxygen (1,000, 10,000, and 50,000 kg/yr) were investigated for this analysis. The parametric sweeps conducted in this analysis provide valuable insight into the expected impact of the various model inputs on plant size. This information can be used to identify the most critical components of the plant and guide future decisions on allocating funding for research and development, providing subsystem developers with appropriate interfaces with downstream and upstream processes, and assessing the overall feasibility of MRE when compared to other ISRU plants. References: [1] Carlson, A. et al. (2024) ICES, ICES-2024-53. [2] Dominguez, D.A., and Sibille, L. (2011) AIAA, AIAA-2011-700. [3] Schreiner, S.S. (2015) MIT, Dissertation. [4] Schreiner, S.S. et al. (2016) ASR, 57(7), pp.1585-1603.

ISRU↗