Sterilization requirements, operational procedures, facilities and hardware.
Space vehicle sterilization and decontamination, discussing dry heat sterilization and Capsule System Advanced Development
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Space vehicle sterilization and decontamination, discussing dry heat sterilization and Capsule System Advanced Development
Decontamination effects of ethylene oxide and thermal sterilization influence on spacecraft polymeric materials and electronic components
Microbiological background information is compiled in handbook for engineers and scientists working on bio-related projects. It is intended as aid in - /1/ evaluating effects of engineering procedures on microbial life, /2/ determining effects of decontamination and sterilization on performance of overall systems, and /3/ understanding language of microbiologists.
Decontaminating potable water supply in Apollo spacecraft using bacteria removal filters
Trace gas control method for decontamination of integrated life support system
Research and development of interferometer, satellite telephone system, berylliumized propellants, and decontamination processes for space hardware
Cleaning and decontamination processes for space hardware
Statistical procedures for investigating decontamination of spacecraft and microbial assays
Thermal inactivation curves of Bacillus subtilis spores for decontamination of interplanetary space vehicle components
OGO-6 surface contamination by outgassing in space environment and decontamination by sputtering and desorption
Ammonia decontaminant control of oxygen difluoride and static and dynamic compatibility tests with plastic and elastomer materials
Oxygen difluoride hazards, chemical and physical properties, decontamination methods, and transfer and storage techniques manual
Planetary quarantine, decontamination, microbial release probabilities, and contamination logs for Venus and Mars
Vacuum package with Ti bulk sublimator/ion pump combination for 150 kv neutron generator tritium decontamination
The bibliography is arranged in separate sections under headings that include: (1) spacecraft cleanliness, (2) general cleaning, (3) clean room and work stations, (4) contamination, (5) decontamination, (6) manufacturing, (7) miscellaneous, (8) particle count analysis, (9) passivation, (10) packaging, (11) water, and (12) acids and detergents.
The efficiency of a biodetection grinder, used to recover buried contamination, was tested using spacecraft components and laminated polystyrene strips containing Bacillus subtilis var. niger spores. The surfaces were decontaminated before tests. Results are given in tabular form. Tables are also given for heat resistance of bacteria spores, prevalence of bacteria in spacecraft before launch, and the types of bacteria found in Apollo 15 spacecraft components and command modules.
Methods for presterilization cleaning or decontamination of spacecraft hardware to reduce microbial load, without harming materials or spacecraft components, are investigated. Three methods were considered: (1) chemicals in liquid form, relying on physical removal as well as bacterial or bacteriostatic action; (2) chemicals used in the gaseous phase, relying on bacterial activity; and (3) mechanical cleaning relying on physical removal of organisms. These methods were evaluated in terms of their effectiveness in microbial burden reduction and compatibility with spacecraft hardware. Results show chemical methods were effective against spore microorganisms but were harmful to spacecraft materials. Mechanical methods were also effective with the degree depending upon the type of instrument employed. Mechanical methods caused problems in handling the equipment, due to vacuum pressure damaging the very thin layered materials used for shielding, and the bristles used in the process caused streaks or abrasions on some spacecraft components.
A description is given of the various kinds of gas and liquid filters used in decontamination and sterilization procedures. Also discussed are filtration mechanisms, characteristics of filter materials, and the factors affecting filter performance. Summaries are included for filter testing and evaluation techniques and the possible application of the filters to spacecraft sterilization.