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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 163 records · Page 9
All sourcesNASA NTRSDOE OSTI
NASA NTRS2019

Approximate Entropy and Sample Entropy: A Comprehensive Tutorial

Approximate Entropy and Sample Entropy are two algorithms for determining the regularity of series of data based on the existence of patterns. Despite their similarities, the theoretical ideas behind those techniques are different but usually ignored. This paper aims to be a complete guideline of the theory and application of the algorithms, intended to explain their characteristics in detail to researchers from different fields. While initially developed for physiological applications, both algorithms have been used in other fields such as medicine, telecommunications, economics or Earth sciences. In this paper, we explain the theoretical aspects involving Information Theory and Chaos Theory, provide simple source codes for their computation, and illustrate the techniques with a step by step example of how to use the algorithms properly. This paper is not intended to be an exhaustive review of all previous applications of the algorithms but rather a comprehensive tutorial where no previous knowledge isrequired to understand the methodology.

Delgado-Bonal, Alfonso↗
NASA NTRS1988

The development of an Ada programming support environment database: SEAD (Software Engineering and Ada Database), user's manual

This is a manual for users of the Software Engineering and Ada Database (SEAD). SEAD was developed to provide an information resource to NASA and NASA contractors with respect to Ada-based resources and activities that are available or underway either in NASA or elsewhere in the worldwide Ada community. The sharing of such information will reduce the duplication of effort while improving quality in the development of future software systems. The manual describes the organization of the data in SEAD, the user interface from logging in to logging out, and concludes with a ten chapter tutorial on how to use the information in SEAD. Two appendices provide quick reference for logging into SEAD and using the keyboard of an IBM 3270 or VT100 computer terminal.

Liaw, Morris↗
NASA NTRS2001

A User's Guide to CGNS

The CFD General Notation System (CGNS) was developed to be a self-descriptive, machine-independent standard for storing CFD aerodynamic data. This guide aids users in the implementation of CGNS. It is intended as a tutorial on the usage of the CGNS mid-level library routines for reading and writing grid and flow solution datasets for both structured and unstructured methodologies.

Rumsey, Christopher L.↗
NASA NTRS2002

RNA-binding proteins in plants: the tip of an iceberg?

RNA-binding proteins, which are involved in the synthesis, processing, transport, translation, and degradation of RNA, are emerging as important, often multifunctional, cellular regulatory proteins. Although relatively few RNA-binding proteins have been studied in plants, they are being identified with increasing frequency, both genetically and biochemically. RNA-binding proteins that regulate chloroplast mRNA stability and translation in response to light and that have been elegantly analyzed in Clamydomonas reinhardtii have counterparts with similar functions in higher plants. Several recent reports describe mutations in genes encoding RNA-binding proteins that affect plant development and hormone signaling.

Review↗
NASA NTRSDate not supplied

fmdtools Tutorial: Intro to Resilience Modelling, Simulation, and Visualization in Python With fmdtools

This workshop will cover the basics of using the fmdtools package for the simulation of hazardous scenarios for resilience simulation. The fmdtools simulation package is an open-source python toolkit for simulating the dynamic response of a system to internal and externally-driven hazardous scenarios, including faults and environmental conditions, that can be used to analyze the risks related to these hazards. Prior to the development of fmdtools, researchers had to either adapt an (often limited) propriety toolkit or develop their own design/simulation/analysis codes to develop their models of hazardous events, a significant technical burden to both (1) leveraging resilience modeling methodologies and (2) extending these methodologies with their own contributions. The fmdtools package provides a number of model constructs and simulation and analysis methods to enable the designer to focus to solely on their modeling case-study while still enabling a significant degree of model expressiveness and adaptability via Python-based model definition. This tutorial will present the setup of fmdtools and a high-level overview of its use, as well as some simple examples for understanding how to leverage its modelling, simulation, and analysis capabilities. Familiarity with jupyter notebook and basic python will be assumed.

Daniel Hulse↗
NASA NTRS2002

Sensorimotor aspects of high-speed artificial gravity: III. Sensorimotor adaptation

As a countermeasure to the debilitating physiological effects of weightlessness, astronauts could live continuously in an artificial gravity environment created by slow rotation of an entire spacecraft or be exposed to brief daily "doses" in a short radius centrifuge housed within a non-rotating spacecraft. A potential drawback to both approaches is that head movements made during rotation may be disorienting and nauseogenic. These side effects are more severe at higher rotation rates, especially upon first exposure. Head movements during rotation generate aberrant vestibular stimulation and Coriolis force perturbations of the head-neck motor system. This article reviews our progress toward distinguishing vestibular and motor factors in side effects of rotation, and presents new data concerning the rates of rotation up to which adaptation is possible. We have studied subjects pointing to targets during constant velocity rotation, because these movements generate Coriolis motor perturbations of the arm but do not involve unusual vestibular stimulation. Initially, reaching paths and endpoints are deviated in the direction of the transient lateral Coriolis forces generated. With practice, subjects soon move in straighter paths and land on target once more. If sight of the arm is permitted, adaptation is more rapid than in darkness. Initial arm movement trajectory and endpoint deviations are proportional to Coriolis force magnitude over a range of rotation speeds from 5 to 20 rpm, and there is rapid, complete motor adaptation at all speeds. These new results indicate that motor adaptation to high rotation rates is possible. Coriolis force perturbations of head movements also occur in a rotating environment but adaptation gradually develops over the course of many head movements.

Non-NASA Center↗
NASA NTRS1991

Imaging radar polarimetry - A review

The authors present a tutorial review of the broad sweep of topics relating to imaging radar polarimetry, ranging from mathematical foundations to hardware and from implementation approaches to signal processing and calibration. The authors examine current developments in sensor technology and implementation for recording polarimetric measurements, and describe techniques and areas of application for this form of remotely sensed data. Those aspects of ground signal processing and calibration peculiar to the polarimetric signals are addressed. Several of the currently operating instruments and some of the implementations planned for future use are discussed.

Zebker, Howard A.↗
NASA NTRSDate not supplied

An Introduction to Data Visualization

Data visualization can be used to present findings, explore data, and use the human eye to find patterns that a computer would struggle to locate. Borrowing tools from art, storytelling, data analytics and software development, data visualization is an indispensable part of the analysis process. While data visualization usage spans across multiple disciplines and sectors, most never receive formal training in the subject. As such, this tutorial will introduce key data visualization building blocks and how to best use those building blocks for different scenarios and audiences. We will also go over tips on accessibility, design and interactive elements. While this will by no means be a complete overview of the data visualization field, by building a foundation and introducing some rules of thumb, attendees will be better equipped for communicating their findings to their audience.

data visualization↗
NASA NTRS2005

Development as adaptation: a paradigm for gravitational and space biology

Adaptation is a central precept of biology; it provides a framework for identifying functional significance. We equate mammalian development with adaptation, by viewing the developmental sequence as a series of adaptations to a stereotyped sequence of habitats. In this way development is adaptation. The Norway rat is used as a mammalian model, and the sequence of habitats that is used to define its adaptive-developmental sequence is (a) the uterus, (b) the mother's body, (c) the huddle, and (d) the coterie of pups as they gain independence. Then, within this framework and in relation to each of the habitats, we consider problems of organismal responses to altered gravitational forces (micro-g to hyper-g), especially those encountered during space flight and centrifugation. This approach enables a clearer identification of simple "effects" and active "responses" with respect to gravity. It focuses our attention on functional systems and brings to the fore the manner in which experience shapes somatic adaptation. We argue that this basic developmental approach is not only central to basic issues in gravitational biology, but that it provides a natural tool for understanding the underlying processes that are vital to astronaut health and well-being during long duration flights that will involve adaptation to space flight conditions and eventual re-adaptation to Earth's gravity.

Non-NASA Center↗
NASA NTRS1998

Perspective on the impact of weightlessness on calcium and bone metabolism

As humans venture into space to colonize the moon and travel to distant planets in the 21st century, they will be confronted with a bone disease that could potentially limit their space exploration activities or put them at risk for fracture when they return to earth. It is now recognized that an unloading of the skeleton, either due to strict bed rest or in zero gravity, leads on average to a 1%-2% reduction in bone mineral density at selected skeletal sites each month. The mechanism by which unloading of the skeleton results in rapid mobilization of calcium stores from the skeleton is not fully understood, but it is thought to be related to down regulation in PTH and 1,25-dihydroxyvitamin D3 production. Bone modeling and mineralization in chick embryos is not affected by microgravity, suggesting that bone cells adapt and ultimately become addicted to gravity in order to maintain a structurally sound skeleton. Strategies need to be developed to decrease microgravity-induced bone resorption by either mimicking gravity's effect on bone metabolism, or enhancing physically or pharmacologically bone formation in order to preserve astronauts' bone health.

short duration↗
NASA NTRS1997

Molecular events underlying skeletal muscle atrophy and the development of effective countermeasures

Skeletal muscle adapts to loading; atrophying when exposed to unloading on Earth or in spaceflight. Significant atrophy (decreases in muscle fiber cross-section of 11-24%) in humans has been noted after only 5 days in space. Since muscle strength is determined both by muscle cross-section and synchronization of motor unit recruitment, a loss in muscle size weakens astronauts, which would increase risks to their safety if an emergency required maximal muscle force. Numerous countermeasures have been tested to prevent atrophy. Resistant exercise together with growth hormone and IGF-I are effective countermeasures to unloading as most atrophy is prevented in animal models. The loss of muscle protein is due to an early decrease in protein synthesis rate and a later increase in protein degradation. The initial decrease in protein synthesis is a result of decreased protein translation, caused by a prolongation in the elongation rate. A decrease in HSP70 by a sight increase in ATP may be the factors prolonging elongation rate. Increases in the activities of proteolytic enzymes and in ubiquitin contribute to the increased protein degradation rate in unloaded muscle. Numerous mRNA concentrations have been shown to be altered in unloaded muscles. Decreases in mRNAs for contractile proteins usually occur after the initial fall in protein synthesis rates. Much additional research is needed to determine the mechanism by which muscle senses the absence of gravity with an adaptive atrophy. The development of effective countermeasures to unloading atrophy will require more research.

Non-NASA Center↗
NASA NTRS1991

Extracellular matrix and cell shape: potential control points for inhibition of angiogenesis

Capillary endothelial (CE) cells require two extracellular signals in order to switch from quiescence to growth and back to differentiation during angiogenesis: soluble angiogenic factors and insoluble extracellular matrix (ECM) molecules. Soluble endothelial mitogens, such as basic fibroblast growth factor (FGF), act over large distances to trigger capillary growth, whereas ECM molecules act locally to modulate cell responsiveness to these soluble cues. Recent studies reveal that ECM molecules regulate CE cell growth and differentiation by modulating cell shape and by activating intracellular chemical signaling pathways inside the cell. Recognition of the importance of ECM and cell shape during capillary morphogenesis has led to the identification of a series of new angiogenesis inhibitors. Elucidation of the molecular mechanism of capillary regulation may result in development of even more potent angiogenesis modulators in the future.

Non-NASA Center↗
NASA NTRS2001

Development of sensory systems in zebrafish (Danio rerio)

Zebrafish possess all of the classic sensory modalities: taste, tactile, smell, balance, vision, and hearing. For each sensory system, this article provides a brief overview of the system in the adult zebrafish followed by a more detailed overview of the development of the system. By far the majority of studies performed in each of the sensory systems of the zebrafish have involved some aspect of molecular biology or genetics. Although molecular biology and genetics are not major foci of the paper, brief discussions of some of the mutant strains of zebrafish that have developmental defects in each specific sensory system are included. The development of the sensory systems is only a small sampling of the work being done using zebrafish and provides a mere glimpse of the potential of this model for the study of vertebrate development, physiology, and human disease.

Non-NASA Center↗
NASA NTRS1992

Extracellular matrix as a solid-state regulator in angiogenesis: identification of new targets for anti-cancer therapy

Angiogenesis, the growth of blood capillaries, is regulated by soluble growth factors and insoluble extracellular matrix (ECM) molecules. Soluble angiogenic mitogens act over large distances to initiate capillary growth whereas changes in ECM govern whether individual cells will grow, differentiate, or involute in response to these stimuli in the local tissue microenvironment. Analysis of this local control mechanism has revealed that ECM molecules switch capillary endothelial cells between differentiation and growth by both binding specific transmembrane integrin receptors and physically resisting cell-generated mechanical loads that are applied to these receptors. Control of capillary endothelial cell form and function therefore may be exerted by altering the mechanical properties of the ECM as well as its chemical composition. Understanding of this mechanochemical control mechanism has led to the development of new angiogenesis inhibitors that may be useful for the treatment of cancer.

Review↗
NASA NTRS2010

Public Participation in Earth Science from the ISS

The Gateway to Astronaut Photography of Earth (GAPE) is an online database (http://eol.jsc.nasa.gov) of terrestrial astronaut photography that enables the public to experience the astronaut s view from orbit. This database of imagery includes all NASA human-directed missions from the Mercury program of the early 1960 s to the current International Space Station (ISS). To date, the total number of images taken by astronauts is 1,025,333. Of the total, 621,316 images have been "cataloged" (image geographic center points determined and descriptive metadata added). The remaining imagery provides an opportunity for the citizen-scientist to become directly involved with NASA through cataloging of astronaut photography, while simultaneously experiencing the wonder and majesty of our home planet as seen by astronauts on board the ISS every day. We are currently developing a public cataloging interface for the GAPE website. When complete, the citizen-scientist will be able to access a selected subset of astronaut imagery. Each candidate will be required to pass a training tutorial in order to receive certification as a cataloger. The cataloger can then choose from a selection of images with basic metadata that is sorted by difficulty levels. Some guidance will be provided (template/pull down menus) for generation of geographic metadata required from the cataloger for each photograph. Each cataloger will also be able to view other contributions and further edit that metadata if they so choose. After the public inputs their metadata the images will be posted to an internal screening site. Images with similar geographic metadata and centerpoint coordinates from multiple catalogers will be reviewed by NASA JSC Crew Earth Observations (CEO) staff. Once reviewed and verified, the metadata will be entered into the GAPE database with the contributors identified by their chosen usernames as having cataloged the frame.

Willis, Kimberly J.↗
DOE OSTI2024

PyOED: An Extensible Suite for Data Assimilation and Model-Constrained Optimal Design of Experiments

This article describes PyOED, a highly extensible scientific package that enables developing and testing model-constrained optimal experimental design (OED) for inverse problems. Specifically, PyOED aims to be a comprehensive Python toolkit for model-constrained OED. The package targets scientists and researchers interested in understanding the details of OED formulations and approaches. It is also meant to enable researchers to experiment with standard and innovative OED technologies with a wide range of test problems (e.g., simulation models). OED, inverse problems (e.g., Bayesian inversion), and data assimilation (DA) are closely related research fields, and their formulations overlap significantly. Thus, PyOED is continuously being expanded with a plethora of Bayesian inversion, DA, and OED methods as well as new scientific simulation models, observation error models, and observation operators. These pieces are added such that they can be permuted to enable testing OED methods in various settings of varying complexities. The PyOED core is completely written in Python and utilizes the inherent object-oriented capabilities; however, the current version of PyOED is meant to be extensible rather than scalable. Specifically, PyOED is developed to “enable rapid development and benchmarking of OED methods with minimal coding effort and to maximize code reutilization.” This article provides a brief description of the PyOED layout and philosophy and provides a set of exemplary test cases and tutorials to demonstrate the potential of the package.

97 MATHEMATICS AND COMPUTING↗
NASA NTRS1988

Nonlinear dynamics in cardiac conduction

Electrical conduction in the heart shows many phenomena familiar from nonlinear dynamics. Among these phenomena are multiple basins of attraction, phase locking, and perhaps period-doubling bifurcations and chaos. We describe a simple cellular-automation model of electrical conduction which simulates normal conduction patterns in the heart as well as a wide range of disturbances of heart rhythm. In addition, we review the application of percolation theory to the analysis of the development of complex, self-sustaining conduction patterns.

NASA Discipline Cardiopulmonary↗
NASA NTRS1988

The habits of roots: what's up down under?

Defining interactions of roots with the surrounding soil environment has been the focus of many recent investigations. As a result of these efforts, we are gaining an appreciation of the varied and often surprising strategies whereby roots adjust to and condition their soil environment for optimal growth and development. This article summarizes current knowledge of the often complex interactions between roots and biotic and abiotic factors within the soil. These interactions are interpreted in terms of modifications in the development or the physiology of the root.

Review↗