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At least 163 records · Page 9

The Fractal-based Analysis of the Regulation of Vascular Remodeling in the Quail Chorioallantoic Membrane

Critical to the advancement of space exploration is the safety and well being of astronauts while in space. This study focuses on the second highest of NASA-defined risk categories for human space exploration, cardiovascular alterations. Current research of this problem is being tackled by investigating angiogenesis through vascular remodeling. Angiogenesis is the growth and formation of new blood vessels. Angiogenesis is an important part of maintaining normal development and bodily functions. The loss of control of this process, either insufficient or excessive vascular growth, is considered a common denominator in many diseases, such as cancer, diabetes, and coronary artery disease. Objectives are presently being met by observing the effects of various regulators, like thrombospondin 1 (TSP-1) and a novel vessel tortuosity factor (TF), through the use of the chorioallantoic membrane (CAM) of Japanese quail embryos, which enables the direct optical imaging of 2-dimensional vascular branching trees. Research within the CAM is being performed to deduce numerous methods of regulating vessel growth. This project centers on the ability of a novel vessel regulator to affect angiogenesis. For example, it is hypothesized that the TSP-1 will inhibit the growth of CAM vasculature. Fractal/VESGEN-based techniques and PTV analysis are the methodologies used to investigate vascular differentiation. This tactic is used to quantify results and measure the growth patterns and morphology of blood vessels. The regulatory mechanisms posed by this vessel regulator can be deduced by alterations found within the vasculature patterns of quail embryos.

Smith, Genee S.↗

Growth and Remodeling in Blood Vessels Studied In Vivo With Fractal Analysis

Every cell in the human body must reside in close proximity to a blood vessel (within approximately 200 mm) because blood vessels provide the oxygen, metabolite, and fluid exchanges required for cellular existence. The growth and remodeling of blood vessels are required to support the normal physiology of embryonic development, reproductive biology, wound healing and adaptive remodeling to exercise, as well as abnormal tissue change in diseases such as cancer, diabetes, and coronary heart disease. Cardiovascular and hemodynamic (blood flow dynamics) alterations experienced by astronauts during long-term spaceflight, including orthostatic intolerance, fluid shifts in the body, and reduced numbers of red (erythrocyte) and white (immune) blood cells, are identified as risk factors of very high priority in the NASA task force report on risk reduction for human spaceflight, the "Critical Path Roadmap."

Parsons-Wingerter, Patricia A.↗

Statistical geometry of a small surface patch in a developed sea

The fractal and marginal fractal regimes in surface geometry are studied. The basic notions of fractal geometry are applied to a small surface patch in a developed sea, corresponding to the equilibrium wave number spectrum. Topothesy, outer and inner boundaries of the fractal range, and a cascade pattern in surface geometry are discussed. Theoretical predictions of whitecap and foam coverage are presented. A fractal decomposition for a surface patch is developed based on the Karhunen-Loeve expansion. The resulting series formalizes the cascade process of constructing realization of a Gaussian random patch. The implications of the research for microwave remote sensing signatures are considered.

Glazman, Roman E.↗

Cascade model for fluvial geomorphology

Erosional landscapes are generally scale invariant and fractal. Spectral studies provide quantitative confirmation of this statement. Linear theories of erosion will not generate scale-invariant topography. In order to explain the fractal behavior of landscapes a modified Fourier series has been introduced that is the basis for a renormalization approach. A nonlinear dynamical model has been introduced for the decay of the modified Fourier series coefficients that yield a fractal spectra. It is argued that a physical basis for this approach is that a fractal (or nearly fractal) distribution of storms (floods) continually renews erosional features on all scales.

Newman, W. I.↗

Analysis of regional deformation and strain accumulation data adjacent to the San Andreas fault

A new approach to the understanding of crustal deformation was developed under this grant. This approach combined aspects of fractals, chaos, and self-organized criticality to provide a comprehensive theory for deformation on distributed faults. It is hypothesized that crustal deformation is an example of comminution: Deformation takes place on a fractal distribution of faults resulting in a fractal distribution of seismicity. Our primary effort under this grant was devoted to developing an understanding of distributed deformation in the continental crust. An initial effort was carried out on the fractal clustering of earthquakes in time. It was shown that earthquakes do not obey random Poisson statistics, but can be approximated in many cases by coupled, scale-invariant fractal statistics. We applied our approach to the statistics of earthquakes in the New Hebrides region of the southwest Pacific because of the very high level of seismicity there. This work was written up and published in the Bulletin of the Seismological Society of America. This approach was also applied to the statistics of the seismicity on the San Andreas fault system.

Turcotte, Donald L.↗

Estimating Trabecular Bone Mechanical Properties From Non-Invasive Imaging

An important component in developing countermeasures for maintaining musculoskeletal integrity during long-term space flight is an effective and meaningful method of monitoring skeletal condition. Magnetic resonance imaging (MRI) is an attractive non-invasive approach because it avoids the exposure to radiation associated with X-ray based imaging and also provides measures related to bone microstructure rather than just density. The purpose of the research for the 1996 Summer Faculty Fellowship period was to extend the usefulness of the MRI data to estimate the mechanical properties of trabecular bone. The main mechanical properties of interest are the elastic modulus and ultimate strength. Correlations are being investigated between these and fractal analysis parameters, MRI relaxation times, apparent densities, and bone mineral densities. Bone specimens from both human and equine donors have been studied initially to ensure high-quality MR images. Specimens were prepared and scanned from human proximal tibia bones as well as the equine distal radius. The quality of the images from the human bone appeared compromised due to freezing artifact, so only equine bone was included in subsequent procedures since these specimens could be acquired and imaged fresh before being frozen. MRI scans were made spanning a 3.6 cm length on each of 5 equine distal radius specimens. The images were then sent to Dr. Raj Acharya of the State University of New York at Buffalo for fractal analysis. Each piece was cut into 3 slabs approximately 1.2 cm thick and high-resolution contact radiographs were made to provide images for comparing fractal analysis with MR images. Dual energy X-ray absorptiometry (DEXA) scans were also made of each slab for subsequent bone mineral density determination. Slabs were cut into cubes for mechanical using a slow-speed diamond blade wafering saw (Buehler Isomet). The dimensions and wet weights of each cube specimen were measured and recorded. Wet weights were also recorded. Each specimen was labeled and marked to denote anatomic orientations, i.e. superior/inferior (S/I), media/lateral (M/L), and anterior/posterior (A/P). The actual locations of each cube cut were documented and images distributed to define ROI locations for other analyses (to Raj Acharya for fractal analysis, to Jon Richardson at Baylor College of Medicine for DEXA, and to Chen Lin at Baylor College of Medicine for T2* MRI analysis). Quasistatic mechanical testing consisted of compressive loading in all three mutually perpendicular anatomic directions. Cyclic loading was applied for 10 cycles to precondition the specimen and results calculated for the eleventh. For one of three directions tested on each specimen, the 10 cycles were followed with loading to failure. Testing is currently proceeding and once completed the results will be correlated with data from the other analyses. One of the main points of interest is the relationship between fractal dimension and mechanical properties. Throughout preparation and testing all specimens were maintained hydrated with physiological saline and stored frozen when not being used.

Hogan, Harry A.↗

Correlation of data on strain accumulation adjacent to the San Andreas Fault with available models

Theoretical and numerical studies of deformation on strike slip faults were performed and the results applied to geodetic observations performed in the vicinity of the San Andreas Fault in California. The initial efforts were devoted to an extensive series of finite element calculations of the deformation associated with cyclic displacements on a strike-slip fault. Measurements of strain accumulation adjacent to the San Andreas Fault indicate that the zone of strain accumulation extends only a few tens of kilometers away from the fault. There is a concern about the tendency to make geodetic observations along the line to the source. This technique has serious problems for strike slip faults since the vector velocity is also along the fault. Use of a series of stations lying perpendicular to the fault whose positions are measured relative to a reference station are suggested to correct the problem. The complexity of faulting adjacent to the San Andreas Fault indicated that the homogeneous elastic and viscoelastic approach to deformation had serious limitations. These limitation led to the proposal of an approach that assumes a fault is composed of a distribution of asperities and barriers on all scales. Thus, an earthquake on a fault is treated as a failure of a fractal tree. Work continued on the development of a fractal based model for deformation in the western United States. In order to better understand the distribution of seismicity on the San Andreas Fault system a fractal analog was developed. The fractal concept also provides a means of testing whether clustering in time or space is a scale-invariant process.

Turcotte, Donald L.↗

Rarefied solids

One important limit to creating low density materials is the objects' own weight. As a solid or colloidal matrix becomes more rarefied, gravity acts destructively to compress its suporting skeleton. We describe experimental results and propose a model which matches the low gravity behavior of rarefied or fractal solids. On parabolic airplane flights, we sought to demonstrate a key component of producing higher surface area fractals. Flight paths were selected to give a range of gravity levels: 0.01 g/g(sub 0) (low), 0.16 g(sub 0) (Lunar), 0.33 g/g(sub 0) (Martian), 1 g/g(sub 0) (Earth) and 1.8 g/g(sub 0) (high) (where g(sub 0) = 980 cm/sq s). Results using the model material of hydrophobic silica indicated that stable agglomeration of such tenuous objects can increase markedly in reduced gravity. Optical characterization revealed that fractal dimension changed directly with varying gravity. As measured by fractal dimension, effective surface area and roughness increased by 40% in low gravity. This finding supports the conclusion that relieving internal weight stresses on delicate aggregates can enhance their overall size (by two orders of magnitude) and internal surface area. We conclude that gravitational restructuring limits the overall size and void content of low-density solids. These sparse colloidal regimes may present new and technologically attractive physics, ranging from improved insulators, liquid-like tension in a 'solid' matrix, and characteristically low conductivities for sound and (8 to 14 micrometers wavelength) infrared radiation.

Noever, D. A.↗

Time and Measurement Days

Questions in data analysis involving the concepts of time and measurement are often pushed into the background or reserved for a philosophical discussion. Some examples are: a) Is causality a consequence of the laws of physics, or can the arrow of time be reversed? b) Can we determine the arrow of time of an event? c) Do we need the continuum hypothesis for the underlying function in any measurement process? d) Can we say anything about the analyticity of the underlying process of an event? e) Would it be valid to model a non-analytical process as function of time? f) What are the implications of all these questions for classical Fourier techniques? However, in the age of big data gathered either from space missions supplying ultra-precise long time series, or e.g. LIGO data from the ground, the moment to bring these questions to the foreground seems arrived. The limitations of our understanding of some fundamental processes is emphasized by the lack of solution for problems open for more than 2 decades, such as the non-detection of solar g-modes, or the modal identification of main sequence stellar pulsators like delta Scuti stars. Flicker noise or 1/f noise, for example, attributed in solar-like stars to granulation, is analyzed mostly only to apply noise reduction techniques, neither considering the classical problem of 1/f noise that was introduced a 100 years ago, nor taking into account ergodic or non-ergodic solutions that make inapplicable spectral analysis techniques in practice. This topic was discussed by Nicholas W. Watkins during the ITISE meeting held in Granada in 2016. There he presented preliminary results of his research on Mandelbrot's related work. We reproduce here his quotation of Mandelbrot (1999) "There is a sharp contrast between a highly anomalous ("non-white") noise that proceeds in ordinary clock time and a noise whose principal anomaly is that it is restricted to fractal time", suggesting a connection with the above proposed topics that could be phrased as the following additional questions:a) Is self-organized criticality (SOC) frequent in astrophysical phenomena? b) Could all fractals in nature be considered stochastic? c) Could we establish mathematical/physical relationships between chaotic and fractal behaviors in time series? d) Could the differences between fractals and chaos in terms of analyticity be used to understand the residuals of the fitting of stellar light curves? In this meeting we would like to approximate these problems from a holistic and multidisciplinary perspective, taking into account not only technical issues but also the deeper implications. In particular the concept of connectivity (introduced in Pascual-Granado et al. A&A, 2015) could be used to implement, within the framework of ARMA processes, an "arrow of time" (see attached document), and so studying the possible implications in the concept of time as envisaged by Watkins.

data analysis↗

Heart rate dynamics before spontaneous onset of ventricular fibrillation in patients with healed myocardial infarcts

The traditional methods of analyzing heart rate (HR) variability have failed to predict imminent ventricular fibrillation (VF). We sought to determine whether new methods of analyzing RR interval variability based on nonlinear dynamics and fractal analysis may help to detect subtle abnormalities in RR interval behavior before the onset of life-threatening arrhythmias. RR interval dynamics were analyzed from 24-hour Holter recordings of 15 patients who experienced VF during electrocardiographic recording. Thirty patients without spontaneous or inducible arrhythmia events served as a control group in this retrospective case control study. Conventional time- and frequency-domain measurements, the short-term fractal scaling exponent (alpha) obtained by detrended fluctuation analysis, and the slope (beta) of the power-law regression line (log power - log frequency, 10(-4)-10(-2) Hz) of RR interval dynamics were determined. The short-term correlation exponent alpha of RR intervals (0.64 +/- 0.19 vs 1.05 +/- 0.12; p <0.001) and the power-law slope beta (-1.63 +/- 0.28 vs -1.31 +/- 0.20, p <0.001) were lower in the patients before the onset of VF than in the control patients, but the SD and the low-frequency spectral components of RR intervals did not differ between the groups. The short-term scaling exponent performed better than any other measurement of HR variability in differentiating between the patients with VF and controls. Altered fractal correlation properties of HR behavior precede the spontaneous onset of VF. Dynamic analysis methods of analyzing RR intervals may help to identify abnormalities in HR behavior before VF.

Non-NASA Center↗

Electromagnetic response and emergent topological orders in transition metal dichalcogenide MoTe 2 bilayers

Twisted bilayer transition metal dichalcogenides, such as MoTe 2 , provide a versatile platform for exploring correlated topological phases. This work investigates the interplay between perpendicular magnetic and electric fields in tuning the electronic structure and emergent topological orders of twisted bilayer MoTe 2 (t-MoTe 2 ) across two distinct regimes: a low-twist-angle phase (θ ≈ 2.1°) hosting multiple Chern bands of identical Chern numbers per valley, and a higher-angle phase (θ ≈ 3.89°) featuring Haldane-like bands with opposite Chern numbers. Using a continuum model incorporating moiré potentials up to second harmonics, we compute the Hofstadter fractal spectra under applied fields, revealing Landau fan structures and magnetic-flux-dependent band topology. These fractal spectra are useful in studying emergent topological orders in terms of the composite fermion picture, where the statistical Chern-Simons flux is approximated as a uniform gauge field. We demonstrate that the system hosts both Jain-sequence fractional Chern insulators (FCIs) and non-Jain fractal FCIs with higher Chern numbers. As a result, the electric field suppresses composite fermion gaps and induces topological quantum phase transitions. Furthermore, our analysis extends to valley-contrasting flux attachment, proposing pathways to describe fractional quantum spin Hall states.

Anyons↗

Lacunarity and intermittency in fluid turbulence

It is shown that oscillations in the high-order moments of turbulent velocity fields are inherent to the fractal character of intermittent turbulence and are a feature of the lacunarity of fractal sets. Oscillations in simple Cantor sets are described, and a single parameter to measure lacunarity is identified. The connection between oscillations in fractals and in the turbulent velocity correlations is discussed using the phenomenological beta model of intermittent turbulence (Frisch et al., 1978).

Smith, L. A.↗

Mechanisms of crustal deformation in the western US

The deformation processes in the western United States were studied, considering both deterministic models and random or statistical models. The role of the intracrustal delamination and mechanisms of crustal thinning were also examined. The application of fractal techniques to understand how the crust is deforming was studied in complex regions. Work continued on the development of a fractal based model for deformation in the western United States. Fractal studies were also extended to the study of topography and the geoid.

Turcotte, Donald L.↗

Dark matter and cosmological nucleosynthesis

Existing dark matter problems, i.e., dynamics, galaxy formation and inflation, are considered, along with a model which proposes dark baryons as the bulk of missing matter in a fractal universe. It is shown that no combination of dark, nonbaryonic matter can either provide a cosmological density parameter value near unity or, as in the case of high energy neutrinos, allow formation of condensed matter at epochs when quasars already existed. The possibility that correlations among galactic clusters are scale-free is discussed. Such a distribution of matter would yield a fractal of 1.2, close to a one-dimensional universe. Biasing, cosmic superstrings, and percolated explosions and hot dark matter are theoretical approaches that would satisfy the D = 1.2 fractal model of the large-scale structure of the universe and which would also allow sufficient dark matter in halos to close the universe.

Schramm, D. N.↗

Cloud spatial structure during the FIRE MS IFO

The fractal properties of clouds observed during the FIRE Marine Stratocumulus Intensive Field Observations (MS IFO) and their effects on the large scale radiative properties of the atmosphere are examined. This involves three states: (1) analysis of LANDSAT Thematic Mapper (TM) cloud data to determine the scaling properties associated with various cloud types; (2) simulation of fractal clouds with realistic scaling properties; and (3) computation of mean radiative properties of fractal clouds as a function of their scaling properties. Thirty-three LANDSAT scenes were acquired as part of the FIRE Marine Stratocumulus IFO in July 1987. They exhibit a wide variety of stratocumulus structures. Analysis has so far focused upon the July 7 scene, in which the NASA ER-2, the BMO C130 and the NCAR Electra repeatedly gathered data across a stratocumulus-fair weather cumulus transition.

Cahalan, Robert F.↗

Self-Consistent Simulation of the Brownian Stage of Dust Growth

It is a widely accepted view that in proto-planetary accretion disks the collision and following sticking of dust particles embedded in the gas eventually leads to the formation of planetesimals (coagulation). For the smallest dust grains, Brownian motion is assumed to be the dominant source of their relative velocities leading to collisions between these dust grains. As the dust grains grow they eventually couple to the turbulent motion of the gas which then drives the coagulation much more efficiently. Many numerical coagulation simulations have been carried out to calculate the fractal dimension of the aggregates, which determines the duration of the ineffective Brownian stage of growth. Predominantly on-lattice and off-lattice methods were used. However, both methods require simplification of the astrophysical conditions. The aggregates found by those methods had a fractal dimension of approximately 2 which is equivalent to a constant, mass-independent friction time. If this value were valid for the conditions in an accretion disk, this would mean that the coagulation process would finally 'freeze out' and the growth of a planetesimal would be impossible within the lifetime of an accretion disk. In order to investigate whether this fractal dimension is model independent, we simulate self-consistently the Brownian stage of the coagulation by an N-particle code. This method has the advantage that no further assumptions about homogeneity of the dust have to be made. In our model, the dust grains are considered as aggregates built up of spheres. The equation of motion of the dust grains is based on the probability density for the diffusive transport within the gas atmosphere. Because of the very low number density of the dust grains, only 2-body-collisions have to be considered. As the Brownian stage of growth is very inefficient, the system is to be simulated over long periods of time. In order to find close particle pairs of the system which are most likely to undergo a collision, we use a particle-in-cell (PIC) method for the early stages of the simulation where the system is still very homogeneous and a tree method later when the particles are more clustered.

Kempf, S.↗