Search NASA⌕ Search

SEARCH · Search NASA

Results for “Prevention”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 163 records · Page 9

A plant genetic network for preventing dysbiosis in the phyllosphere

The aboveground parts of terrestrial plants, collectively called the phyllosphere, have a key role in the global balance of atmospheric carbon dioxide and oxygen. The phyllosphere represents one of the most abundant habitats for microbiota colonization. Whether and how plants control phyllosphere microbiota to ensure plant health is not well understood. Here we show that the Arabidopsis quadruple mutant (min7 fls2 efr cerk1; hereafter, mfec)1, simultaneously defective in pattern-triggered immunity and the MIN7 vesicle-trafficking pathway, or a constitutively activated cell death1 (cad1) mutant, carrying a S205F mutation in a membrane-attack-complex/perforin (MACPF)-domain protein, harbour altered endophytic phyllosphere microbiota and display leaf-tissue damage associated with dysbiosis. The Shannon diversity index and the relative abundance of Firmicutes were markedly reduced, whereas Proteobacteria were enriched in the mfec and cad1S205F mutants, bearing cross-kingdom resemblance to some aspects of the dysbiosis that occurs in human inflammatory bowel disease. Bacterial community transplantation experiments demonstrated a causal role of a properly assembled leaf bacterial community in phyllosphere health. Here, the pattern-triggered immune signalling, MIN7 and CAD1 are found in major land plant lineages and are probably key components of a genetic network through which terrestrial plants control the level and nurture the diversity of endophytic phyllosphere microbiota for survival and health in a microorganism-rich environment.

59 BASIC BIOLOGICAL SCIENCES↗

A small molecule inhibitor prevents gut bacterial genotoxin production

Abstract The human gut bacterial genotoxin colibactin is a possible key driver of colorectal cancer (CRC) development. Understanding colibactin’s biological effects remains difficult owing to the instability of the proposed active species and the complexity of the gut microbiota. Here, we report small molecule boronic acid inhibitors of colibactin biosynthesis. Designed to mimic the biosynthetic precursor precolibactin, these compounds potently inhibit the colibactin-activating peptidase ClbP. Using biochemical assays and crystallography, we show that they engage the ClbP binding pocket, forming a covalent bond with the catalytic serine. These inhibitors reproduce the phenotypes observed in a clbP deletion mutant and block the genotoxic effects of colibactin on eukaryotic cells. The availability of ClbP inhibitors will allow precise, temporal control over colibactin production, enabling further study of its contributions to CRC. Finally, application of our inhibitors to related peptidase-encoding pathways highlights the power of chemical tools to probe natural product biosynthesis.

Biochemistry & Molecular Biology↗

Standing shock prevents propagation of sparks in supersonic explosive flows

Abstract Volcanic jet flows in explosive eruptions emit radio frequency signatures, indicative of their fluid dynamic and electrostatic conditions. The emissions originate from sparks supported by an electric field built up by the ejected charged volcanic particles. When shock-defined, low-pressure regions confine the sparks, the signatures may be limited to high-frequency content corresponding to the early components of the avalanche-streamer-leader hierarchy. Here, we image sparks and a standing shock together in a transient supersonic jet of micro-diamonds entrained in argon. Fluid dynamic and kinetic simulations of the experiment demonstrate that the observed sparks originate upstream of the standing shock. The sparks are initiated in the rarefaction region, and cut off at the shock, which would limit their radio frequency emissions to a tell-tale high-frequency regime. We show that sparks transmit an impression of the explosive flow, and open the way for novel instrumentation to diagnose currently inaccessible explosive phenomena.

58 GEOSCIENCES↗

Protection of U.S. streams is insufficient to safeguard stream diversity and prevent habitat impairment

Despite covering a small portion of Earth’s surface, streams support a disproportionate amount of biodiversity. Here, we measure progress against the Global Biodiversity Framework 30×30 protection target for streams within the conterminous U.S., in terms of quantity, representation, and effectiveness of habitat protection under primarily land-based protection strategies. We evaluated the geophysical and biogeographical diversity of streams falling under protection measures. Additionally, we expose a paradox of streams being protected yet simultaneously impaired from human disturbances. Without considering impairment, approximately 30% of streams are currently protected through land-based conservation of their local or upstream watersheds; when considering impairment, only 9% to 28% of streams are truly protected from disturbances depending on impairment thresholds and protection criteria. Furthermore, despite protection approaching 30×30 targets, only 5% of the most prevalent physical stream habitat types are protected. We provide a targeted protection strategy, overcoming the impairment paradox and ensuring adequate representation of streams.

Biogeography↗

Preventing leaching from lead water pipes with electrochemistry: an exploratory study

Toxic levels of lead leaching from ageing water distribution infrastructure affect over 5000 public drinking water systems in the US. Pipe replacement, the most effective solution to this problem, is prohibitively expensive. Additionally, chemical conditioning of drinking water using orthophosphates, although cost-effective, does not quickly stop lead leaching once it has started. We propose a novel approach to stop lead leaching: to rapidly form an insoluble scale within lead pipes using an external power supply. We report on the feasibility of this approach by first anodizing lead coupons and lead pipes reclaimed from a local water distribution using a phosphate electrolyte and different potentials, pH values, and phosphate concentrations. We subsequently exposed these anodized lead coupons and pipes to synthetic tap water to evaluate their lead leaching rates. We found that polarizing lead coupons in the presence of a 0.05 M phosphate solution decreased lead leaching by up to a 100-fold, relative to leaching from polished bare lead. Similarly, polarizing the reclaimed lead pipes (with a preexisting scale) decreased lead leaching from an average of 36 ppb to 7 ppb. These results were observed when applying potentials that favor Pb(IV) formation, which resulted in the buildup of PbO 2 and Pb 5 (PO 4 ) 3 OH in both lead coupons and pipes. Our findings indicate that this novel technology has the potential to rapidly decrease equilibrium lead levels in tap water below the EPA action limit of 15 ppb, and thus deserves further exploration.

54 ENVIRONMENTAL SCIENCES↗

A graph embedding‐based approach for automatic cyber‐physical power system risk assessment to prevent and mitigate threats at scale

Abstract Power systems are facing an increasing number of cyber incidents, potentially leading to damaging consequences to both physical and cyber aspects. However, the development of analytical methods for the study of large‐scale power infrastructures as cyber‐physical systems is still in its early stages. Drawing inspiration from machine‐learning techniques, the authors introduce a method inspired by the principles of graph embedding that is tailored for quantitative risk assessment and the exploration of possible mitigation strategies of large‐scale cyber‐physical power systems. The primary advantage of the graph embedding approach lies in its ability to generate numerous random walks on a graph, simulating potential access paths. Meanwhile, it enables capturing high‐dimensional structures in low‐dimensional spaces, facilitating advanced machine‐learning applications, and ensuring scalability and adaptability for comprehensive network analysis. By employing this graph embedding‐based approach, the authors present a structured and methodical framework for risk assessment in cyber‐physical systems. The proposed graph embedding‐based risk analysis framework aims to provide a more insightful perspective on cyber‐physical risk assessment and situation awareness for power systems. To validate and demonstrate its applicability, the method has been tested on two cyber‐physical power system models: the Western System Coordinating Council (WSCC) 9‐Bus System and the Illinois 200‐Bus System , thereby showing its advantages in enhancing the accuracy of risk analysis and comprehensiveness of situational awareness.

Sun, Shining↗

Preventing ash from poisoning proton–boron 11 fusion plasmas

Proton–boron 11 (pB11) fusion is safe and clean, but also difficult to harness for breakeven power production. Particularly deleterious are fusion-born alpha particles, which massively increase both plasma pressure and bremsstrahlung losses unless they are pulled promptly from the plasma. We show that even if one cannot extract the alphas quickly, one can still achieve net power production, by separating the plasma into two regions: a fusion region, accessible to all species, and an alpha storage region, accessible only to alphas and electrons. This new demixing strategy could make pB11 fusion much easier to achieve.

Ochs, Ian E. (ORCID:0000000260029169)↗

Ballooning instability preventing the H-mode access in plasmas with negative triangularity shape on the DIII-D tokamak

Infinite toroidal mode number (n=∞ ) ballooning mode analysis of negative triangularity discharges on DIII-D shows that the access to 2nd stability becomes strongly restricted when the top triangularity decreases even modestly from -0.18 to -0.36. This is observed in experiment to coincide with the suppression of the L-H-transition. Further theoretical analysis with ballooning mode limited pedestals shows that the threshold for opening the 2nd stability access rises from a pedestal temperature of 0.3 keV to 1 keV when the top triangularity is decreased from -0.18 to -0.36 indicating that to access the 2nd stability with the more negative triangular shape would require unrealistically high pedestal temperature. Furthermore, the pedestal predicted by the EPED code agrees with the experimental H-mode profile for the negative triangularity case but in contrast to positive triangular shapes the prediction shows no increase in pedestal height with increasing core pressure when triangularity is negative. This work provides a first model to predict when negative triangularity plasmas can be expected to access the H-mode.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Metal Halide Perovskite Solar Module Encapsulation Using Polyolefin Elastomers: The Role of Morphology in Preventing Delamination

The development of perovskite solar cells (PSCs) has ushered in a new era of solar technology, characterized by its exceptional efficiency and cost-effective production. However, the soft and fragile nature of perovskites makes module encapsulation challenging. Polyolefin elastomers (POEs) have been reported to be promising encapsulants for perovskite modules. However, little research exists on identifying criteria among different types of POEs as encapsulants. Here, two POEs with different morphologies were compared as encapsulants. The first POE crystallizes during encapsulation (crystal content ∼40%), and the resulting shrinkage or warpage leads to delamination, causing minimodule failure. In contrast, perovskite minimodules encapsulated with a mostly amorphous POE exhibited better reliability and reproducibility. The best perovskite minimodules passed the thermal cycling test for 240 cycles between −40 and 85 °C and the damp heat test for 1419 h, according to the IEC 61215 standard. This study highlights the importance of the morphology of encapsulants in achieving high-quality encapsulation. Published by the American Physical Society 2024

14 SOLAR ENERGY↗

A New High-Impedance-Fault Detection Method to Prevent Power-Line-Induced Wildfires

High Impedance Faults (HIFs) occur when energized power lines come into contact with high impedance ground surfaces, such as tree branches and grassland. HIFs have the potential to cause arcing, leading to vegetation ignition and the initiation of wildfires. The challenge in detecting HIFs comes from the high impedance of the partially conductive materials in contact with the power lines. They create a fault current of low magnitude and traditional protective devices struggle to detect such faults. This paper proposes a novel HIF detection algorithm based upon the analyzed arcing signatures associated with HIFs. The algorithm is evaluated using the Australian Public Bushfire Safety Program (PBSP) dataset. For comparative analysis, a state-of-the-art commercial HIF detection product is also evaluated using the same dataset. The proposed algorithm demonstrates higher detection accuracy over the commercial products with fewer false flags and undetected faults.

grasslands↗

Encoding Frequency Constraints in Preventive Unit Commitment Using Deep Learning With Region-of-Interest Active Sampling

With the increasing penetration of renewable energy, frequency response and its security are of significant concerns for reliable power system operations. Frequency-constrained unit commitment (FCUC) is proposed to address this challenge. Despite existing efforts in modeling frequency characteristics in unit commitment (UC), current strategies can only handle oversimplified low-order frequency response models and do not consider wide-range operating conditions. This paper presents a generic data-driven framework for FCUC under high renewable penetration. Here, deep neural networks (DNNs) are trained to predict the frequency response using real data or high-fidelity simulation data. Next, the DNN is reformulated as a set of mixed-integer linear constraints to be incorporated into the ordinary UC formulation. In the data generation phase, all possible power injections are considered, and a region-of-interest active sampling is proposed to include power injection samples with frequency nadirs closer to the UFLC threshold, which enhances the accuracy of frequency constraints in FCUC. The proposed FCUC is investigated on the IEEE 39-bus system. Then, a full-order dynamic model simulation using PSS/E verifies the effectiveness of FCUC in frequency-secure generator commitments.

42 ENGINEERING↗