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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 163 records · Page 9
All sourcesNASA NTRSDOE OSTI
NASA NTRS1995

Theoretical Analysis of a Pulse Tube Regenerator

A theoretical analysis of the behavior of a typical pulse tube regenerator has been carried out. Assuming simple sinusoidal oscillations, the static and oscillatory pressures, velocities and temperatures have been determined for a model that includes a compressible gas and imperfect thermal contact between the gas and the regenerator matrix. For realistic material parameters, the analysis reveals that the pressure and, velocity oscillations are largely independent of details of the thermal contact between the gas and the solid matrix. Only the temperature oscillations depend on this contact. Suggestions for optimizing the design of a regenerator are given.

Roach, Pat R.↗
NASA NTRS1997

Automated Reuse of Scientific Subroutine Libraries through Deductive Synthesis

Systematic software construction offers the potential of elevating software engineering from an art-form to an engineering discipline. The desired result is more predictable software development leading to better quality and more maintainable software. However, the overhead costs associated with the formalisms, mathematics, and methods of systematic software construction have largely precluded their adoption in real-world software development. In fact, many mainstream software development organizations, such as Microsoft, still maintain a predominantly oral culture for software development projects; which is far removed from a formalism-based culture for software development. An exception is the limited domain of safety-critical software, where the high-assuiance inherent in systematic software construction justifies the additional cost. We believe that systematic software construction will only be adopted by mainstream software development organization when the overhead costs have been greatly reduced. Two approaches to cost mitigation are reuse (amortizing costs over many applications) and automation. For the last four years, NASA Ames has funded the Amphion project, whose objective is to automate software reuse through techniques from systematic software construction. In particular, deductive program synthesis (i.e., program extraction from proofs) is used to derive a composition of software components (e.g., subroutines) that correctly implements a specification. The construction of reuse libraries of software components is the standard software engineering solution for improving software development productivity and quality.

Lowry, Michael R.↗
NASA NTRS1997

Pulse Tube Coolers with an Inertance Tube: Theory, Modeling and Practice

We have studied the advantages to be gained by replacing the conventional orifice of a pulse tube cooler by an inertance tube - a long thin tube that introduces the possibility for additional phase shift between pressure and mass flow in the pulse tube section. The case for the use of an inertance tube is most clearly made with an electrical analogy where the 'inductance' added by the inertance tube allows for optimal power transfer at the cold heat exchanger. Detailed modeling of a pulse tube system with an inertance tube confirms these advantages. Comparison between a laboratory cooler with an orifice and with an inertance tube will be presented and reasons wily it is difficult to realize all the expected gain will be given.

Roach, Pat R.↗
NASA NTRS1998

Using Decision Procedures to Build Domain-Specific Deductive Synthesis Systems

This paper describes a class of decision procedures that we have found useful for efficient, domain-specific deductive synthesis. These procedures are called closure-based ground literal satisfiability procedures. We argue that this is a large and interesting class of procedures and show how to interface these procedures to a theorem prover for efficient deductive synthesis. Finally, we describe some results we have observed from our implementation. Amphion/NAIF is a domain-specific, high-assurance software synthesis system. It takes an abstract specification of a problem in solar system mechanics, such as 'when will a signal sent from the Cassini spacecraft to Earth be blocked by the planet Saturn?', and automatically synthesizes a FORTRAN program to solve it.

VanBaalen, Jeffrey↗
NASA NTRS2002

The Hematopoietic Stem Cell Therapy for Exploration of Space

Astronauts experience severe/invasive disorders caused by space environments. These include hematological/cardiac abnormalities, bone and muscle losses, immunodeficiency, neurological disorders and cancer. While the cause of these symptoms are not yet fully delineated, one possible explanation could be the inhibition of hematopoietic stem cell (HSC) growth and hematopoiesis in space. HSCs differentiate into all types of blood cells, and growing evidence indicates that the HSCs also have the ability to transdifferentiate to various tissues, including muscle, skin, liver, neuronal cells and possibly bone. Therefore, a hypothesis was advanced in this laboratory that the hematopoietic stem cell-based therapy, herein called the hematopoietic stem cell therapy (HSCT), could mitigate some of the disorders described above. Due to the magnitude of this project our laboratory has subdivided it into 3 sections: a) HSCT for space anemia; b) HSCT for muscle and bone losses; and c) HSCT for immunodeficiency. Toward developing the HSCT protocol for space anemia, the HSC transplantation procedure was established using a mouse model of beta thalassemia. In addition, the NASA Rotating Wall Vessel (RWV) culture system was used to grow HSCs in space condition. To investigate the HSCT for muscle loss and bone loss, donor HSCs were genetically marked either by transfecting the beta-galactosidase-containing plasmid, pCMV.SPORT-beta-gal or by preparing from b-galactosidase transgenic mice. The transdifferentiation of HSCs to muscle is traced by the reporter gene expression in the hindlimb suspended mice with some positive outcome, as studied by the X-gal staining procedure. The possible structural contribution of HSCs against muscle loss is being investigated histochemically.

Roach, Allana Nicole↗
NASA NTRS2004

Cryocoolers for Space

Many planetary and Earth science missions require cooling to increase sensitivity and reduce thermal noise of detectors, for preserving high Isp propellants, or for protecting instruments from hostile environments. For space applications, such cooling requires reliable, efficient, long-life coolers that are relatively compact, lightweight, and have low vibration. We have developed and are developing coolers that meet these requirements over a wide range of temperatures. These include pulse tube coolers cooling from 300 K to below 6 K, a magnetic cooler cooling from 10 K to 2 K, a 3He sorption cooler cooling from 2 K to 0.3 K and a helium dilution cooler cooling from 0.3 K to 0.05 K. Details of these coolers and their advantages are presented.

Kittel, Peter↗
NASA NTRS2003

The Hematopoietic Stem Cell Therapy for Exploration of Deep Space

It is hypothesized that the hematopoietic stem cell therapy (HSCT) might countermeasure various space-caused disorders so as to maintain astronauts' homeostasis. If this were achievable, the HSCT could promote human exploration of deep space. Using animal models of disorders (hindlimb suspension unloading system and beta-thalassemia), the HSCT was tested for muscle loss, immunodeficiency and space anemia. The results indicate feasibility of HSCT for these disorders. To facilitate the HSCT in space, growth of HSCs were optimized in the NASA Rotating Wall Vessel (RWV) culture systems, including Hydrodynamic Focusing Bioreactor (HFB).

Ohi, Seigo↗
NASA NTRS1997

Ventilation during simulated altitude, normobaric hypoxia and normoxic hypobaria

To investigate the possible effect of hypobaria on ventilation (VE) at high altitude, we exposed nine men to three conditions for 10 h in a chamber on separate occasions at least 1 week apart. These three conditions were: altitude (PB = 432, FIO2 = 0.207), normobaric hypoxia (PB = 614, FIO2 = 0.142) and normoxic hypobaria (PB = 434, FIO2 = 0.296). In addition, post-test measurements were made 2 h after returning to ambient conditions at normobaric normoxia (PB = 636, FIO2 = 0.204). In the first hour of exposure VE was increased similarly by altitude and normobaric hypoxia. The was 38% above post-test values and end-tidal CO2 (PET(CO2) was lower by 4 mmHg. After 3, 6 and 9 h, the average VE in normobaric hypoxia was 26% higher than at altitude (p < 0.01), resulting primarily from a decline in VE at altitude. The difference between altitude and normobaric hypoxia was greatest at 3 h (+ 39%). In spite of the higher VE during normobaric hypoxia, the PET(CO2) was higher than at altitude. Changes in VE and PET(CO2) in normoxic hypobaria were minimal relative to normobaric normoxia post-test measurements. One possible explanation for the lower VE at altitude is that CO2 elimination is relatively less at altitude because of a reduction in inspired gas density compared to normobaric hypoxia; this may reduce the work of breathing or alveolar deadspace. The greater VE during the first hour at altitude, relative to subsequent measurements, may be related to the appearance of microbubbles in the pulmonary circulation acting to transiently worsen matching. Results indicate that hypobaria per se effects ventilation under altitude conditions.

NASA Discipline Environmental Health↗
NASA NTRS2004

Hematopoietic Stem Cell Therapy as a Counter-Measure for Human Exploration of Deep Space

Human exploration of deep space depends, in part, on our ability to counter severe/invasive disorders that astronauts experience in space environments. The known symptoms include hematological/cardiac abnormalities,bone and muscle losses, immunodeficiency, neurological disorders, and cancer. Exploiting the extraordinary plasticity of hematopoietic stem cells (HSCs), which differentiate not only to all types of blood cells, but also to various tissues, we have advanced a hypothesis that ome of the space-caused disorders maybe amenable to hematopoietis stem cell therapy(HSCT) so as to maintain promote human exploration of deep space. Using mouse models of human anemia beta-thaiassemia) as well as spaceflight (hindlimb unloading system), we have obtained feasibility results of HSCT for space anemia, muscle loss, and immunodeficiency. For example, in the case of HSCT for muscle loss, the beta-galactosidese marked HSCs were detected in the hindlimbs of unloaded mouse following transplantation by -X-gal wholemaunt staining procedure. Histochemicaland physical analyses indicated structural contribution of HSCs to the muscle. HSCT for immunodeficiency was investigated ising beta-galactosidese gene-tagged Escherichia coli as the infectious agent. Results of the X-gal staining procedure indicated the rapeutic role of the HSCT. To facilitate the HSCT in space, growth of HSCs were optimized in the NASA Rotating Wall Vessel (RWV) culture systems, including Hydrodynamic Focusing Bioreactor (HFB).

Ohi, S.↗
NASA NTRS2004

Hematopoietic Stem Cell Therapy to Countermeasure Cancer in Astronauts during Exploration of Deep Space

Exposure to cosmic radiation can cause chromosomal mutations, which may lead to cancer in astronauts engaged in space exploration. Therefore, our goals are to develop countermeasures to prevent space-induced cancer using hematopoietic stem cell therapy (HSCT) and gene therapy. This presentation focuses on HSCT for cancer. Our previous experiments on a simulated, space-induced immuno-deficiency model (mouse hind limb unloading ) indicated that transplanted hematopoietic stem cells (HSCs) could enhance the host's immunity by effectively eliminating bacterial infection (Ohi S, et. al. J Grav Physiol 10, P63-64, 2003; Ohi S, et. al. Proceedings of the Space Technology and Applications International Forum (STAIF) . American Institute of Physics, New York, pp. 938-950, 2004). Hence, we hypothesized that the HSCs might be effective in combating cancer as well. Studies of cocultured mouse HSCs with beta-galactosidase marked rat gliosarcoma spheroids (9L/lacZ), a cancer model, indicated antagonistic interactions , resulting in destruction of the spheroids by HSCs. Trypan Blue dye-exclusion assays were consistent with the conclusion. These results show potential usehlness of HSCT for cancer. Currently, the NASA Hydrodynamic Focusing Bioreactor (HFB), a space analog tissue/cell culture system, is being used to study invasion of the gliosarcoma (GS) spheroids into mouse brain with or without co-cultured HSCs. This may simulate the metastasis of gliosarcoma to brain. There is a tendency for the HSCs to inhibit invasion of GS spheroids into brain, as evidenced by the X-gal staining.

Ohi, S.↗
NASA NTRS2009

Propulsion Investigation for Zero and Near-Zero Emissions Aircraft

As world emissions are further scrutinized to identify areas for improvement, aviation s contribution to the problem can no longer be ignored. Previous studies for zero or near-zero emissions aircraft suggest aircraft and propulsion system sizes that would perform propulsion system and subsystems layout and propellant tankage analyses to verify the weight-scaling relationships. These efforts could be used to identify and guide subsequent work on systems and subsystems to achieve viable aircraft system emissions goals. Previous work quickly focused these efforts on propulsion systems for 70- and 100-passenger aircraft. Propulsion systems modeled included hydrogen-fueled gas turbines and fuel cells; some preliminary estimates combined these two systems. Hydrogen gas-turbine engines, with advanced combustor technology, could realize significant reductions in nitrogen emissions. Hydrogen fuel cell propulsion systems were further laid out, and more detailed analysis identified systems needed and weight goals for a viable overall system weight. Results show significant, necessary reductions in overall weight, predominantly on the fuel cell stack, and power management and distribution subsystems to achieve reasonable overall aircraft sizes and weights. Preliminary conceptual analyses for a combination of gas-turbine and fuel cell systems were also performed, and further studies were recommended. Using gas-turbine engines combined with fuel cell systems can reduce the fuel cell propulsion system weight, but at higher fuel usage than using the fuel cell only.

Snyder, Christopher A.↗
NASA NTRS2007

Simple, Compact, Safe Impact Tester

An apparatus has been designed and built for testing the effects, on moderate-sized objects, of cushioned decelerations having magnitudes ranging up to several hundred g [where g = normal Earth gravitational acceleration (approximately 9.8 m/s(exp 2))].

Roach, Pat R.↗
NASA NTRS2010

A Terminal Area Analysis of Continuous Ascent Departure Fuel Use at Dallas/Fort Worth International Airport

Aircraft departing from the Dallas/Fort Worth International Airport (DFW) encounter vertical restrictions that prevent continuous ascent operations. The result of these restrictions are temporary level-offs at 10,000 feet. A combination of flow direction, specific Area Navigation (RNAV) route geometry, and arrival streams have been found to be the biggest factors in the duration and frequency of a temporary level-offs. In total, 20% of DFW departures are affected by these level-offs, which have an average duration of just over 100 seconds. The use of continuous descent approaches at DFW are shown to lessen the impact arrivals have on the departures and allow more continuous ascents. The fuel used in a continuous ascent and an ascent with a temporary level-off have been calculated using a fuel burn rate model created from a combination of actual aircraft track data, aircraft manufacturer flight operations manuals, and Eurocontrol's Base of Aircraft Data (BADA) simulation tool. This model represents the average aggregate burn rates for the current fleet mix at DFW. Continuous ascents would save approximately seven gallons of fuel out of 450 gallons used to climb to a cruise altitude of 31,000ft per departure.

Roach, Keenan↗
NASA NTRS2006

Insulating Material for Next-Generation Spacecraft

A report discusses the development of a flexible thermal-insulation material for cryogenic tanks in next-generation spacecraft. This material is denoted Advanced Reusable All-temperature Multimode Insulation System (ARAMIS). The report begins by describing the need for ARAMIS and the technological challenges of developing a single material that is useable throughout the temperature range from storage of liquid hydrogen (20 K) to atmospheric-reentry heating (>2,000 K), has the requisite low thermal conductivity, resists condensation of moisture without need for a gas purge, and withstands reentry heating for a 400-mission lifetime. The report then discusses laboratory apparatuses for testing materials that have been and will be considered as candidates for the development of ARAMIS.

White, Susan↗