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At least 163 records · Page 9

The Star Formation History of Orion and its Environs

During the period of performance, we have obtained the following observations and carried out the analysis of the Orion associations itemized below: 1) Detailed analysis of newly discovered stars in strips at declinations +1 degree and -1 degree; 2) Disk evolution in the Ori OB1 association; 3) Spitzer proposal; 4) Multifiber echelle spectroscopy; 5) Slit spectroscopy of bright candidates; 6) Other multifiber spectroscopy; 7) UBVRI photometry; 8) Near and mid-IR photometry.

Calvert, Nuria↗

Enabling Model Organism and Commercial Astronaut Data Access Through the NASA Open Science Data Repository

NASA’s Open Science Data Repository (OSDR) brings together omics data from NASA’s GeneLab project and non-omics data, including physiological, phenotypic, imaging, and behavioral data from NASA’s Ames Life Sciences Data Archive (ALSDA) collected from decades of space biology research, providing open and FAIR (findable, accessible, interoperable, and reusable) access of these precious data to scientists world-wide. This rich source of meticulously curated metadata and data from spaceflight and analog studies has been mined by the scientific community resulting in dozens of high impact scientific publications that reveals a complex network of molecular and physiological effects of spaceflight across living systems, from microbes to plants, to mammals. Understanding how these effects translate to the human condition is critical as we move deeper into the era of commercial space travel. However, the integration of data, specifically omics data, from astronauts is particularly challenging due to their sensitive nature. OSDR has risen to this challenge by developing a mechanism to control access to identifiable levels of omics data, such as raw sequence data, while enabling public access to processed, unidentifiable, data and associated metadata that will allow the scientific community to interrogate human astronaut data alongside data from model organisms to begin answering these critical questions. The 2021 SpaceX Inspiration4 (I4) mission collected a comprehensive atlas of biological measurements from four civilian astronauts, providing a wealth of data to characterize the effects of spaceflight on the human body. These data include both non-omics and omics assays such as direct RNA sequencing (RNA-seq), single nuclei ATAC-seq and RNA-seq, metagenomics, proteomics, and comprehensive metabolic and cytokine panels, all of which have been integrated into the OSDR system across no less than 9 studies. Each study has been carefully curated using community-backed OSDR standards for sample and assay level metadata ensuring these data are findable and accessible. In addition to hosting both raw and processed data from the principal investigator team for each assay type, the GeneLab team plans to re-process the I4 omics data using GeneLab’s standard processing pipelines. The GeneLab processed data outputs will allow for comparisons across studies on OSDR and enable visualization of these data through the OSDR data visualization platform thereby enabling data reusability and interoperability. Here we describe the robust privacy and security protocols implemented by OSDR to safeguard sensitive health data from astronauts while facilitating metadata and processed data sharing for research purposes. We further provide a road map for navigating the vast amount of data provided for each I4 study on the OSDR, including experimental design, associated experiments, payloads, and missions, data generation and analysis protocols, and associated scientific articles. Additionally, we illustrate how to interrogate the standardized metadata provided in the sample and assay tables as well as various means to download and access the data including programmatically through the GeneLab Open API (GLOpenAPI). The open access of datasets in NASA’s OSDR provides a unique opportunity for the scientific community, as well as citizen scientists and students, to continue using OSDR resources to further unlock profound insights into the consequences of space travel on the human body. Through implementation of security measures to protect sensitive human data, the OSDR seeks to strengthen the science exchange between the Biological and Physical Sciences Program and the Human Research Program, per recommendation 4-1 of the 2023-2032 Decadal Survey, and encourage further sharing and dissemination of astronaut data to provide the scientific community with the resources needed to lay the groundwork for developing targeted mitigation strategies to help withstand the rigors of long-duration spaceflight.

Amanda Marie Saravia-butler↗

Enabling Model Organism and Commercial Astronaut Data Access Through the NASA Open Science Data Repository

NASA’s Open Science Data Repository (OSDR) brings together omics data from NASA’s GeneLab project and non-omics data, including physiological, phenotypic, imaging, and behavioral data from NASA’s Ames Life Sciences Data Archive (ALSDA) collected from decades of space biology research, providing open and FAIR (findable, accessible, interoperable, and reusable) access of these precious data to scientists world-wide. This rich source of meticulously curated metadata and data from spaceflight and analog studies has been mined by the scientific community resulting in dozens of high impact scientific publications that reveals a complex network of molecular and physiological effects of spaceflight across living systems, from microbes to plants, to mammals. Understanding how these effects translate to the human condition is critical as we move deeper into the era of commercial space travel. However, the integration of data, specifically omics data, from astronauts is particularly challenging due to their sensitive nature. OSDR has risen to this challenge by developing a mechanism to control access to identifiable levels of omics data, such as raw sequence data, while enabling public access to processed, unidentifiable, data and associated metadata that will allow the scientific community to interrogate human astronaut data alongside data from model organisms to begin answering these critical questions. The 2021 SpaceX Inspiration4 (I4) mission collected a comprehensive atlas of biological measurements from four civilian astronauts, providing a wealth of data to characterize the effects of spaceflight on the human body. These data include both non-omics and omics assays such as direct RNA sequencing (RNA-seq), single nuclei ATAC-seq and RNA-seq, metagenomics, proteomics, and comprehensive metabolic and cytokine panels, all of which have been integrated into the OSDR system across no less than 9 studies. Each study has been carefully curated using community-backed OSDR standards for sample and assay level metadata ensuring these data are findable and accessible. In addition to hosting both raw and processed data from the principal investigator team for each assay type, the GeneLab team plans to re-process the I4 omics data using GeneLab’s standard processing pipelines. The GeneLab processed data outputs will allow for comparisons across studies on OSDR and enable visualization of these data through the OSDR data visualization platform thereby enabling data reusability and interoperability. Here we describe the robust privacy and security protocols implemented by OSDR to safeguard sensitive health data from astronauts while facilitating metadata and processed data sharing for research purposes. We further provide a road map for navigating the vast amount of data provided for each I4 study on the OSDR, including experimental design, associated experiments, payloads, and missions, data generation and analysis protocols, and associated scientific articles. Additionally, we illustrate how to interrogate the standardized metadata provided in the sample and assay tables as well as instructions for how to download and access the data. The I4 datasets described here re present the first ever comprehensive collection of commercial astronaut data.

Amanda M Saravia-Butler↗

Magnetic field directional discontinuities. I - Minimum variance errors

The paper deals with a statistical analysis of the errors associated with a minimum variance analysis of directional discontinuities by use of an idealized model of these discontinuities and various simulations, and also by an examination of actual Mariner 10 interplanetary magnetic field data. An empirical expression is derived for the magnitude of the error in an estimated discontinuity normal component, relative to the total field across the directional discontinuity. The analysis was performed primarily to aid in differentiating between interplanetary tangential and rotational discontinuities observed by Mariner 10.

Lepping, R. P.↗

A dissimilatory nitrite reductase in Paracoccus halodenitrificans

Paracoccus halodenitrificans produced a membrane-associated nitrite reductase. Spectrophotometric analysis showed it to be associated with a cd-cytochrome and located on the inner side of the cytoplasmic membrane. When supplied with nitrite, membrane preparations produced nitrous oxide and nitric oxide in different ratios depending on the electron donor employed. The nitrite reductase was maximally active at relatively low concentrations of sodium chloride and remained attached to the membranes at 100 mM sodium chloride.

Grant, M. A.↗

Development, refinement, and testing of a short term solar flare prediction algorithm

Progress toward performance of the tasks and accomplishing the goals set forth in the two year Research Grant included primarily analysis of digital data sets and determination of methodology associated with the analysis of the very large, unique, and complex collection of digital solar magnetic field data. The treatment of each magnetogram as a unique set of data requiring special treatment was found to be necessary. It is determined that a person familiar with the data, the analysis system, and logical, coherent outcome of the analysis must conduct each analysis, and interact with the analysis program(s) significantly sometimes many iterations for successful calibration and analysis of the data set. With this interaction, the data sets yield valuable, coherent analyses. During this period, it was also decided that only data sets taken inside heliographic longitudes (Central Meridian Distance) East and West 30 degrees (within 30 degrees of the Central Meridian of the Sun). If the total data set is then found to be numerically inadequate for the final analysis, 30 - 45 degrees Central Meridian Distance data will then be analyzed. The Optical Data storage system (MSFC observatory) was found appropriate for use both in intermediate storage of the data (preliminary to analysis), and for storage of the analyzed data sets for later parametric extraction.

Smith, Jesse B., Jr.↗

A design for a new catalog manager and associated file management for the Land Analysis System (LAS)

Due to the larger number of different types of files used in an image processing system, a mechanism for file management beyond the bounds of typical operating systems is necessary. The Transportable Applications Executive (TAE) Catalog Manager was written to meet this need. Land Analysis System (LAS) users at the EROS Data Center (EDC) encountered some problems in using the TAE catalog manager, including catalog corruption, networking difficulties, and lack of a reliable tape storage and retrieval capability. These problems, coupled with the complexity of the TAE catalog manager, led to the decision to design a new file management system for LAS, tailored to the needs of the EDC user community. This design effort, which addressed catalog management, label services, associated data management, and enhancements to LAS applications, is described. The new file management design will provide many benefits including improved system integration, increased flexibility, enhanced reliability, enhanced portability, improved performance, and improved maintainability.

Greenhagen, Cheryl↗

A Rat Body Phantom for Radiation Analysis

To reduce the uncertainties associated with estimating the biological effects of ionizing radiation in tissue, researchers rely on laboratory experiments in which mono-energetic, single specie beams are applied to cell cultures, insects, and small animals. To estimate the radiation effects on astronauts in deep space or low Earth orbit, who are exposed to mixed field broad spectrum radiation, these experimental results are extrapolated and combined with other data to produce radiation quality factors, radiation weighting factors, and other risk related quantities for humans. One way to reduce the uncertainty associated with such extrapolations is to utilize analysis tools that are applicable to both laboratory and space environments. The use of physical and computational body phantoms to predict radiation exposure and its effects is well established and a wide range of human and non-human phantoms are in use today. In this paper, a computational rat phantom is presented, as well as a description of the process through which that phantom has been coupled to existing radiation analysis tools. Sample results are presented for two space radiation environments.

Qualls, Garry D.↗

Subscale and Full-Scale Testing of Buckling-Critical Launch Vehicle Shell Structures

New analysis-based shell buckling design factors (aka knockdown factors), along with associated design and analysis technologies, are being developed by NASA for the design of launch vehicle structures. Preliminary design studies indicate that implementation of these new knockdown factors can enable significant reductions in mass and mass-growth in these vehicles and can help mitigate some of NASA s launch vehicle development and performance risks by reducing the reliance on testing, providing high-fidelity estimates of structural performance, reliability, robustness, and enable increased payload capability. However, in order to validate any new analysis-based design data or methods, a series of carefully designed and executed structural tests are required at both the subscale and full-scale level. This paper describes recent buckling test efforts at NASA on two different orthogrid-stiffened metallic cylindrical shell test articles. One of the test articles was an 8-ft-diameter orthogrid-stiffened cylinder and was subjected to an axial compression load. The second test article was a 27.5-ft-diameter Space Shuttle External Tank-derived cylinder and was subjected to combined internal pressure and axial compression.

Hilburger, Mark W.↗

Analysis of Aviation Safety Reporting System Incident Data Associated With the Technical Challenges of the Vehicle Systems Safety Technology Project

This analysis was conducted to support the Vehicle Systems Safety Technology (VSST) Project of the Aviation Safety Program (AVsP) milestone VSST4.2.1.01, "Identification of VSST-Related Trends." In particular, this is a review of incident data from the NASA Aviation Safety Reporting System (ASRS). The following three VSST-related technical challenges (TCs) were the focus of the incidents searched in the ASRS database: (1) Vechicle health assurance, (2) Effective crew-system interactions and decisions in all conditions; and (3) Aircraft loss of control prevention, mitigation, and recovery.

Withrow, Colleen A.↗

Measurement and analysis of critical crack tip processes associated with variable amplitude fatigue crack growth

Crack growth retardation following overloads can result in overly conservative life predictions in structures subjected to variable amplitude fatigue loading when linear damage accumulation procedures are employed. Crack closure is believed to control the crack growth retardation, although the specific closure mechanism is debatable. Information on the relative contributions to crack closure from: (1) plasticity left in the wake of the advancing crack and (2) crack tip residual stresses is provided. The delay period and corresponding crack growth rate transients following overloads are systematically measured as a function of load ratio (R) and overload magnitude. These responses are correlated in terms of the local 'driving force' for crack growth as measured by crack tip opening loads and delta K sub eff. The latter measurements are obtained using a scanning electron microscope equipped with a cyclic loading stage; measurements are quantified using a relatively new stereoimaging technique. Combining experimental results with analytical predictions suggests that both plastic wake and residual stress mechanism are operative, the latter becoming predominate as R increases.

Hudak, S. J., Jr.↗

On computational schemes for global-local stress analysis

An overview is given of global-local stress analysis methods and associated difficulties and recommendations for future research. The phrase global-local analysis is understood to be an analysis in which some parts of the domain or structure are identified, for reasons of accurate determination of stresses and displacements or for more refined analysis than in the remaining parts. The parts of refined analysis are termed local and the remaining parts are called global. Typically local regions are small in size compared to global regions, while the computational effort can be larger in local regions than in global regions.

Reddy, J. N.↗

NASA Marshall Space Flight Center Human Factors Engineering Analysis of Various Hatch Sizes and Associated Safety Impacts

The NASA Docking System (NDS) is a 31.5-inch (800-millimeter)-diameter circular hatch for astronauts to pass through when docked to other pressurized elements in space or for surface egress. The NDS is utilized on the Orion Spacecraft and has been implemented as the International Docking System Standard (IDSS). The EV74 Human Factors Engineering (HFE) Team at NASA’s Marshall Space Flight Center (MSFC) conducted human factors analyses with various hatch shapes and sizes to accommodate for all astronaut anthropometries, task comfort, and task safety. The 32-inch hatch is too small and a bigger hatch size would better accommodate most astronauts and prove to be safer for daily pass-throughs. To conduct human factors analyses, four participants were gathered based on anthropometry: 1st female, 5th female, 95th male, and 99th male.

Andrews, Tanya C.↗

Sensitivity of wildlife habitat models to uncertainties in GIS data

Decision makers need to know the reliability of output products from GIS analysis. For many GIS applications, it is not possible to compare these products to an independent measure of 'truth'. Sensitivity analysis offers an alternative means of estimating reliability. In this paper, we present a CIS-based statistical procedure for estimating the sensitivity of wildlife habitat models to uncertainties in input data and model assumptions. The approach is demonstrated in an analysis of habitat associations derived from a GIS database for the endangered California condor. Alternative data sets were generated to compare results over a reasonable range of assumptions about several sources of uncertainty. Sensitivity analysis indicated that condor habitat associations are relatively robust, and the results have increased our confidence in our initial findings. Uncertainties and methods described in the paper have general relevance for many GIS applications.

Stoms, David M.↗

Development of a miniature mass analyzer and associated instrumentation for improved capabilities in the analysis of low energy plasmas from a rocket or satellite platform

The University of Texas at Dallas (UTD) Center for Space Sciences (CSS) has designed, developed, and fabricated three miniature mass spectrometers and their associated instrumentation in fulfillment of a NASA contract. The ion mass spectrometer analyzers furnished under this contract were modeled after a unit developed during a previous NASA grant. Three assemblies are described: (1) the magnetic sector; (2) the ion detector; and (3) the amplifier and power supply.

Hoffman, John H.↗

Finite element shell instability analysis

Formulation procedures and the associated computer program for finite element thin shell instability analysis are discussed. Data cover: (1) formulation of basic element relationships, (2) construction of solution algorithms on both the conceptual and algorithmic levels, and (3) conduction of numerical analyses to verify the accuracy and efficiency of the theory and related programs therein are described.

Source record↗

Spherical roller bearing analysis. SKF computer program SPHERBEAN. Volume 1: Analysis

The models and associated mathematics used within the SPHERBEAN computer program for prediction of the thermomechanical performance characteristics of high speed lubricated double row spherical roller bearings are presented. The analysis allows six degrees of freedom for each roller and three for each half of an optionally split cage. Roller skew, free lubricant, inertial loads, appropriate elastic and friction forces, and flexible outer ring are considered. Roller quasidynamic equilibrium is calculated for a bearing with up to 30 rollers per row, and distinct roller and flange geometries are specifiable. The user is referred to the material contained here for formulation assumptions and algorithm detail.

Kleckner, R. J.↗