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At least 163 records · Page 9

Early detection of disease program: Evaluation of the cellular immune response

The early cellular responses of specific components of the leukocyte and epithelial cell populations to foreign challenges of both an infectious and noninfectious character were evaluated. Procedures for screening potential flight crews were developed, documented, and tested on a control population. Methods for preparing suitable populations of lymphocytes, polymorphonuclear leukocytes, macrophages, and epithelial cells were first established and evaluated. Epithelial cells from viral infected individuals were screened with a number of anti-viral antisera. This procedure showed the earliest indication of disease as well as providing a specific diagnosis to the physicians. Both macrophages and polymorphonuclear leukocytes were studied from normal individuals, smokers, and patients with viral infections. Newer techniques enabling better definition of lymphocyte subpopulations were then developed, namely the E and EAC rosette procedures for recognition of T (thymus-derived) and B (bone-marrow-derived) lymphocyte subpopulations. Lymphocyte and lymphocyte subpopulation response to multiple mitogens have been evaluated.

Criswell, B. S.↗

Cellular immune response experiment MA-031

Significant changes in phytohemagglutinin (PHA) lymphocytic responsiveness occurred in the cellular immune response of three astronauts during the 9 day flight of the Apollo Soyuz Test Project. Parameters studied were white blood cell concentrations, lymphocyte numbers, B- and T-lymphocyte distributions in peripheral blood, and lymphocyte responsiveness to PHA, pokeweed mitogen, Concanavalin A, and influenza virus antigen.

Criswell, B. S.↗

Relative toxicity of pyrolysis products of some cellular polymers

Twelve samples of cellular polymers were evaluated in the course of developing test methods for toxic materials characterization. Six samples were flexible polyurethane foams, three were rigid polyurethane foams, two were high density rigid foams, and one was a modified polyimide foam. Some effects of formulation variables are discussed.

Hilado, C. J.↗

A model to determine open or closed cellular convection

A simple mechanism is proposed to explain the observed presence in the atmosphere of open or closed cellular convection. If convection is produced by cooling concentrated near the top of the cloud layer, as in radiative cooling of stratus clouds, it develops strong descending currents which are compensated by weak ascent over most of the horizontal area, and closed cells result. Conversely, heating concentrated near the bottom of a layer, as when an air mass is heated by warm water, results in strong ascending currents compensated by weak descent over most of the area, or open cells. This mechanism is similar to the one suggested by Stommel (1962) to explain the smallness of the oceans' sinking regions. The mechanism is studied numerically by means of a two-dimensional, nonlinear Boussinesq model.

Helfand, H. M.↗

Detection of strength limiting defects in cellular glasses by dielectric measurements

The foamed glasses that are being considered for structural support in solar thermal energy system silvered glass concentrator mirrors are assessed for strength-limiting defects by a nondestructive technique which measures the capacitance of well defined regions. The feasibility of locating large defects is demonstrated for the case of one type of cellular mass. Observed capacitance variations are believed to be due to small voids or other irregularities in the material. If the defects are equal to or greater than approximately 20 times the glass matrix pore size, they can be resolved with sufficient accuracy to delineate their spatial extent.

Gammell, P. M.↗

Cellular localization of Na(+), K(+)-ATPase in the mammalian vestibular system

Two different, but complementary, procedures for cellular localization of Na+, K+-ATPase in the guinea pig vestibular system were employed. One of these techniques, devised by Stirling, depends upon the well documented ability of the specific inhibitor ouabain to bind selectively to Na+,K+-ATPase, blocking catalytic activity. Microdisected vestibular tissues are incubated with tritium-labelled (3H-) ouabain, and regions with a high concentration of Na+,K+-ATPase are subsequently identified by light microscope autoradiography. A second method, originated by Ernst, detects inorganic phosphate released from an artificial substrate (nitrophenyl phosphate) by catalytic activity of the enzyme. In the presence of strontium ion, phosphate is precipitated near regions of high activity, then converted to a product which may finally be visualized in the electron microscope. This cytochemical enzymatic reaction is inhibited by ouabain.

Kerr, T. P.↗

Cellular and dendritic growth in a binary melt - A marginal stability approach

A simple model for the constrained growth of an array of cells or dendrites in a binary alloy in the presence of an imposed positive temperature gradient in the liquid is proposed, with the dendritic or cell tip radius calculated using the marginal stability criterion of Langer and Muller-Krumbhaar (1977). This approach, an approach adopting the ad hoc assumption of minimum undercooling at the cell or dendrite tip, and an approach based on the stability criterion of Trivedi (1980) all predict tip radii to within 30 percent of each other, and yield a simple relationship between the tip radius and the growth conditions. Good agreement is found between predictions and data obtained in a succinonitrile-acetone system, and under the present experimental conditions, the dendritic tip stability parameter value is found to be twice that obtained previously, possibly due to a transition in morphology from a cellular structure with just a few side branches, to a more fully developed dendritic structure.

Laxmanan, V.↗

New cellular automaton model for magnetohydrodynamics

A new type of two-dimensional cellular automation method is introduced for computation of magnetohydrodynamic fluid systems. Particle population is described by a 36-component tensor referred to a hexagonal lattice. By appropriate choice of the coefficients that control the modified streaming algorithm and the definition of the macroscopic fields, it is possible to compute both Lorentz-force and magnetic-induction effects. The method is local in the microscopic space and therefore suited to massively parallel computations.

Chen, Hudong↗

Cellular automaton formulation of passive scalar dynamics

Cellular automata modeling of the advection of a passive scalar in a two-dimensional flow is examined in the context of discrete lattice kinetic theory. It is shown that if the passive scalar is represented by tagging or 'coloring' automation particles a passive advection-diffusion equation emerges without use of perturbation expansions. For the specific case of the hydrodynamic lattice gas model of Frisch et al. (1986), the diffusion coefficient is calculated by perturbation.

Chen, Hudong↗

A study of the propagation, dynamics, and extinguishment of cellular flames using microgravity techniques

The characteristics of premixed gas flames in mixtures with low Lewis numbers, free of natural convection effects, were investigated and found to be dominated by diffusive-thermal instabilities. For sufficiently reactive mixtures, cellular structures resulting from these instabilities were observed and found to spawn new cells in regular patterns. For less reactive mixtures, cells formed shortly after ignition but did not spawn new cells; instead these cells evolved into a flame structure composed of stationary, apparently stable spherical flamelets. As a result of these phenomena, well-defined flammability limits were not observed. The experimental results are found to be in qualitative agreement with a simple analytical model based on the interaction of heat release due to chemical reaction, differential diffusion of thermal energy and mass, flame front curvature, and heat losses due to gas radiation.

Ronney, Paul D.↗

Theory of multicolor lattice gas - A cellular automaton Poisson solver

The present class of models for cellular automata involving a quiescent hydrodynamic lattice gas with multiple-valued passive labels termed 'colors', the lattice collisions change individual particle colors while preserving net color. The rigorous proofs of the multicolor lattice gases' essential features are rendered more tractable by an equivalent subparticle representation in which the color is represented by underlying two-state 'spins'. Schemes for the introduction of Dirichlet and Neumann boundary conditions are described, and two illustrative numerical test cases are used to verify the theory. The lattice gas model is equivalent to a Poisson equation solution.

Chen, H.↗

Early Archean (approximately 3.4 Ga) prokaryotic filaments from cherts of the apex basalt, Western Australia: The oldest cellularly preserved microfossils now known

In comparison with that known from later geologic time, the Archean fossil record is miniscule: although literally hundreds of Proterozoic formations, containing more that 2800 occurrences of bona fide microfossils are now known, fewer than 30 units containing some 43 categories of putative microfossils (the vast majority of which are of questionable authenticity) have been reported from the Archean. Among the oldest known fossils are Early Archean filaments reported from cherts of the Towers Formation and the Apex Basalt of the 3.3-3.6 Ga-old Warrawoona Group of Western Australia. The paleobiologic significance of the Towers Formation microstructures is open to question: thin aggregated filaments are properly regarded as dubiomicrofossils (perhaps biogenic, but perhaps not); therefore, they cannot be regarded as firm evidence of Archean life. Although authentic, filamentous microfossiles were reported from a second Towers Formation locality, because the precise layer containing the fossiliferous cherts was not relocated, this discovery can neither be reconfirmed by the original collector nor confirmed independently by other investigators. Discovery of microfossils in bedded cherts of the Apex Basalt, the stratigraphic unit immediately overlying the Towers Formation, obviates the difficulties stored above. The cellularly preserved filaments of the Apex Basalt meet all of the criteria required of a bona fide Archean microfossils. Recent studies indicate that the Apex assemblage includes at least six morphotypes of uniseriate filaments, composed of barrel-shaped, discoidal, or quadrate cells and exhibiting rounded or conical terminal cells and medial bifurcated and paired half-cells that reflect the occurrence of prokaryotic binary cell division. Interestingly, the majority of these morphotypes are morphologically more similar to extant cyanobacteria than to modern filamentous bacteria. Prokaryotes seem clearly to have been hypobradytelic, and the evidence suggests (but does not prove) that physiologically advanced oxygen-producing photosynthesizers may have been represented in the Early Archean biota.

Schopf, J. W.↗

Effects of fade distribution on a mobile satellite downlink and uplink performance in a frequency reuse cellular configuration

In a mobile satellite system with a frequency reuse cellular configuration, significant co-channel interference can be experienced due to the antenna sidelobe level. The signal will be subjected not only to its own fading, but also to the effect of the varying degree of fading on co-channel interferer, and this interference will behave differently in the up and in the down link. This paper presents a quantitative evaluation of the combined effects of fades and co-channel interference on a mobile satellite link.

Boutin, Karl↗

The Pan-European Digital Cellular (GSM) System

This paper presents an overview of the Pan-American Cellular System (GSM). Much of the information is generic to the GSM architecture and operation, as defined in ETSI Recommendations 1 to 12.

Lev, Valy↗

Issues for the integration of satellite and terrestrial cellular networks for mobile communications

Satellite and terrestrial cellular systems naturally complement each other for land mobile communications, even though present systems have been developed independently. The main advantages of the integrated system are a faster wide area coverage, a better management of overloading traffic conditions, an extension to geographical areas not covered by the terrestrial network and, in perspective, the provision of only one integrated system for all mobile communications (land, aeronautical, and maritime). To achieve these goals, as far as possible the same protocols of the terrestrial network should be used also for the satellite network. Discussed here are the main issues arising from the requirements of the main integrated system. Some results are illustrated, and possible future improvements due to technical solutions are presented.

Delre, Enrico↗

A scale-invariant cellular-automata model for distributed seismicity

In the standard cellular-automata model for a fault an element of stress is randomly added to a grid of boxes until a box has four elements, these are then redistributed to the adjacent boxes on the grid. The redistribution can result in one or more of these boxes having four or more elements in which case further redistributions are required. On the average added elements are lost from the edges of the grid. The model is modified so that the boxes have a scale-invariant distribution of sizes. The objective is to model a scale-invariant distribution of fault sizes. When a redistribution from a box occurs it is equivalent to a characteristic earthquake on the fault. A redistribution from a small box (a foreshock) can trigger an instability in a large box (the main shock). A redistribution from a large box always triggers many instabilities in the smaller boxes (aftershocks). The frequency-size statistics for both main shocks and aftershocks satisfy the Gutenberg-Richter relation with b = 0.835 for main shocks and b = 0.635 for aftershocks. Model foreshocks occur 28 percent of the time.

Barriere, Benoit↗

Cellular convection in the atmosphere of Venus

Among the most intriguing feature of the atmosphere of Venus is the presence of cellular structures near and downwind of the subpolar point. It has been suggested that the structures are atmospheric convection cells, but their breadth and thinness would pose a severe challenge to the dynamics of convection. It is proposed here that strongly penetrative convection into the stable regions above and below the neutrally stable cloud layer coupled with penetrative convection from the surface increases the vertical dimensions of the cells, thereby helping to explain their large horizontal extent.

Baker, R. D., II↗