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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 163 records · Page 9
All sourcesNASA NTRSDOE OSTI
NASA NTRS2014

Influential Factors for Liquid Acquisition Device Screen Selection for Cryogenic Propulsion Systems

This paper presents the influential factors which govern screen selection for liquid acquisition devices (LADs) operating in microgravity conditions for future in-space cryogenic propulsion engines and cryogenic propellant depots. Space flight requirements, which include mass flow rate, acceleration level and direction, and thermal environment, dictate screen selection for a particular mission. The five influential factors include bubble point pressure, flow-through-screen pressure drop, wicking rate, screen compliance, and material compatibility. Governing equations and analytical models for these parameters are developed from first principles. A comprehensive survey of the historical data on coarser LAD meshes over four decades of work is conducted, and liquid hydrogen data for finer Dutch Twill meshes (325 x 2300, 450 x 2750, 510 x 3600) from recently concluded experiments is also presented to validate analytical models. Each of these parameters is measurable from ground based tests, making it facile to predict flight system performance. Therefore analytical models in this paper will be valuable for future LAD designs for both cryogenic and storable propulsion systems. Additionally, analysis will be given on the impact of the factors on liquid hydrogen systems.

Fuel Depot↗
DOE OSTI2022

Impact of landscape design on the greenhouse gas emissions of shrub willow bioenergy buffers in a US Midwest corn-production landscape

Previous studies have evaluated the economics and ecosystem services of perennial bioenergy crops when replacing grain crops on marginal (environmentally critical and/or underproductive) lands. This study used life-cycle analysis (LCA) to investigate the greenhouse gas (GHG) emissions of perennial crops when grown in targeted landscape positions and their impact in reducing nitrogen leaching. Specifically, LCA was performed to evaluate the GHG emissions of growing shrub willow on marginal lands in the Indian Creek watershed in Illinois to assess the sustainability of strategically planted willow buffer strips. Willow was grown as a short-rotation woody crop with a 21-year rotation under three scenarios including a business-as-usual (BAU) field-scale production with nitrogen fertilizer application and two unfertilized subfield buffer scenarios – landscape single subfield (LSSF) or landscape multiple subfields (LMSF) – grown alongside cornfields to reduce nitrate leaching. Each scenario also considers three field sizes, 2.0, 10.1, and 40.5 ha. The average annual GHG emissions from willow production and depot transportation were 0.32–0.77 Mg-CO 2 e ha-1 with the lowest emissions for the LSSF scenario and highest for the BAU. The GHG emissions for the LSSF and BAU scenarios are independent of field size, whereas LMSF emissions increase with increasing field size, 0.41 Mg-CO 2 e ha-1 at 2.0 ha and 0.76 Mg-CO 2 e ha-1 at 40.5 ha. Emission results were most sensitive to the willow yield, followed by fertilizer application rate (BAU only), harvest fuel consumption, and transportation distance.

09 BIOMASS FUELS↗
DOE OSTI2020

A Ligand-Directed Nitrophenol Carbonate for Transient in situ Bioconjugation and Drug Delivery

Here we report the first use of ligand-directed proximity accelerated bioconjugation chemistry in the tandem delivery and release of a therapeutic payload. To do this, we designed a nitrophenol carbonate for ligand-directed in situ bioconjugation of a prodrug payload to a protein. The transient nature of our conjugation chemistry renders the protein a depot for timedependent release of active drug following hydrolysis and selfimmolation. In our model system, using an immunostimulant prodrug, biotin ligand, and avidin protein, we observe release of bioavailable immunostimulant both spectroscopically and with an immune cell line over 48 h. Avidin co-crystalized with the nitrophenolate directing group verified the binding pose of the ligand and offered insight into the mechanism of in situ bioconjugation. Overall, this scaffold warrants further investigation for the time-dependent delivery of therapeutics and use in protein ligand pairs beyond biotin and avidin used for this work.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2023

Scattered–light–sheet microscopy with sub–cellular resolving power

Since its first demonstration over 100 years ago, scattering-based light-sheet microscopy has recently re-emerged as a key modality in label-free tissue imaging and cellular morphometry; however, scattering-based light-sheet imaging with subcellular resolution remains an unmet target to date. This is because related approaches inevitably superimpose speckle or granular intensity modulation on to the native subcellular features. Here, we addressed this challenge by deploying a time-averaged pseudo-thermalized light-sheet illumination. While pseudo-thermalizing the illumination sheet increased its lateral dimensions, we achieved subcellular resolving power at ultralow irradiance levels after image deconvolution. We validated this approach by imaging cytosolic carbon depots in yeast and bacteria with increased specificity and no staining. Altogether, we expect this scattering-based light-sheet microscopy approach will advance live single-cell imaging investigations by conferring low-irradiance and label-free operation towards eradicating phototoxicity.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2023

Time-Dependent Electric Bus and Charging Station Deployment Problem

Battery electric buses (BEBs) have gained popularity due to their emission-free and energy-efficient features. Many transit authorities worldwide have set goals to gradually replace their bus fleets with BEBs. Considering the potential decline in BEB battery and charger prices, this study proposes a time-dependent bus fleet transition model to determine the optimal bus fleet transition plan, which includes selecting the bus lines to be electrified, determining the timing and type of BEBs to be purchased, and deploying on-route fast chargers and depot chargers. The model is a bi-objective integer linear program that considers the trade-off between electrified transit mileages and bus electrification costs. A normalized normal constraint method is applied to solve the bi-objective optimization model. The effectiveness of the proposed model is tested using a real-world bus network. Additionally, sensitivity analyses are conducted to better understand the impact of different parameter values on the optimal solutions. Our proposed model can provide transit authorities with a powerful tool to make informed decisions about their BEB fleet replacement plans.

ADVANCED PROPULSION SYSTEMS↗
DOE OSTI2024

Aerial drone fleet deployment optimization with endogenous battery replacements for direct delivery of time-sensitive products

Aerial drones offer a distinct potential to reduce the delivery time and energy consumption for the delivery of time-sensitive and small products. However, there is still a need in the relevant industry to understand the performance of drone-based delivery under different business needs and drone operating conditions. We studied a drone deployment optimization problem for direct delivery of time-sensitive products with release dates to customers maintaining a specified time window. This paper presents a new mixed-integer programming model, new valid inequalities, a new greedy heuristic algorithm, and a Genetic algorithm to help business owners optimally schedule and route their drone fleet minimizing the required fleet size, the required number of additional batteries, and total energy consumption. A realistic feature of the optimization method is that instead of replacing the drone battery after each return to the depot, it keeps track of the remaining energy in the drone battery and decides on battery replacements accounting for the drone routing and the user-specified minimum required battery energy. Numerical results based on real data from drone flight tests and prepared food delivery industry provide insights into the effect of different practical drone operating parameters on the required fleet size, the required number of battery replacements, and energy consumption. Here, results demonstrate that the proposed heuristic algorithm substantially outperforms the accelerated CPLEX in runtime while sacrificing the solution quality by a small amount. Additionally, results show that using a mixed fleet of hexacopter and quadcopter drones reduces the total energy consumption by 48.52% compared to using a homogeneous fleet of only hexacopters.

Drone energy consumption↗
DOE OSTI2023

Molecular homing and retention of muscle membrane stabilizing copolymers by non-invasive optical imaging in vivo

First-in-class membrane stabilizer Poloxamer 188 (P188) has been shown to confer membrane protection in an extensive range of clinical conditions; however, elements of the systemic distribution and localization of P188 at the organ, tissue, and muscle fiber levels in vivo have not yet been elucidated. Here we used non-invasive fluorescence imaging to directly visualize and track the distribution and localization of P188 in vivo. The results demonstrated that the Alx647 probe did not alter the fundamental properties of P188 to protect biological membranes. Distribution kinetics in mdx mice demonstrated that Alx647 did not interface with muscle membranes and had fast clearance kinetics. In contrast, the distribution kinetics for P188-Alx647 was significantly slower, indicating a dramatic depot and retention effect of P188. Results further demonstrated the significant retention of P188-Alx647 in the skeletal muscle of mdx mice, showing a significant genotype effect with a higher fluorescence signal in the mdx muscles over BL10 mice. High-resolution optical imaging provided direct evidence of P188 surrounding the sarcolemma of skeletal and cardiac muscle cells. Taken together, these findings provide direct evidence of muscle-disease-dependent molecular homing and retention of synthetic copolymers in striated muscles thereby facilitating advanced studies of copolymer-membrane association in health and disease.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2023

Transportation and electricity systems integration via electric vehicle charging-as-a-service: A review of techno-economic and societal benefits

Here, in support of global decarbonization efforts, the adoption of electric vehicles is proceeding rapidly across transportation sectors, population groups, and regions. However, access to electric vehicle charging infrastructure remains sparse and inequitable, and technical, economic, and procedural challenges have encumbered its expansion. Charging-as-a-service, which can mitigate cost and effort risks of charging equipment ownership, adds a means of meeting many of these challenges. As charging-as-a-service has not been analyzed or addressed in the scholarly literature, we synthesize media, marketing, and analogous scholarly publications to categorize and describe the functions asserted by existing charging-as-a-service vendors. We demonstrate and quantify the benefits of many of these functions via four example business cases, sited at a detached residence, a multi-unit dwelling, a consumer-facing business, and a commercial fleet depot. Outcomes show that savings and revenues realized via charging-as-a-service can reduce charging costs, beneficially shape grid loads, and make charging installation economical where it otherwise would not be. Discussion highlights the need to deploy charging-as-a-service in cooperation with initiatives promoting societal benefits, including charging access equity.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗
DOE OSTI2026

Extreme-scale EV charging infrastructure planning for last-mile delivery using high-performance parallel computing

Here, this paper addresses stochastic charger location and allocation problems under queue congestion for last-mile delivery using electric vehicles (EVs). The objective is to decide where to open charging stations and how many chargers of each type to install, subject to budgetary and waiting-time constraints. We formulate the problem as a mixed-integer non-linear program, where each station-charger pair is modeled as a multiserver queue with stochastic arrivals and service times to capture the notion of waiting in fleet operations. The model is extremely large, with billions of variables and constraints for a typical metropolitan area; even loading the model in solver memory is difficult, let alone solving it. To address this challenge, we develop a Lagrangian-based dual decomposition framework that decomposes the problem by station and leverages parallelization on high-performance computing systems, where the subproblems are solved by using a cutting plane method and their solutions are collected at the master level. We also develop a three-step rounding heuristic to transform the fractional subproblem solutions into feasible integral solutions. Computational experiments on data from the Chicago metropolitan area with hundreds of thousands of households and thousands of candidate stations show that our approach produces high-quality solutions in cases where existing exact methods cannot even load the model in memory. We also analyze various policy scenarios, demonstrating that combining existing depots with newly built stations under multiagency collaboration substantially reduces costs and congestion. These findings offer a scalable and efficient framework for developing sustainable large-scale EV charging networks.

Capacity allocation↗
DOE OSTI2021

Human adipose-derived mesenchymal stromal cells from face and abdomen undergo replicative senescence and loss of genetic integrity after long-term culture

Body fat depots are heterogeneous concerning their embryonic origin, structure, exposure to environmental stressors, and availability. Thus, investigating adipose-derived mesenchymal stromal cells (ASCs) from different sources is essential to standardization for future therapies. In vitro amplification is also critical because it may predispose cell senescence and mutations, reducing regenerative properties and safety. Here, we evaluated long-term culture of human facial ASCs (fASCs) and abdominal ASCs (aASCs) and showed that both met the criteria for MSCs characterization but presented differences in their immunophenotypic profile, and differentiation and clonogenic potentials. The abdominal tissue yielded more ASCs, and these had higher proliferative potential, but facial cells displayed fewer mitotic errors at higher passages. However, both cell types reduced clonal efficiency over time and entered replicative senescence around P12, as evaluated by progressive morphological alterations, reduced proliferative capacity, and SA-β-galactosidase expression. Loss of genetic integrity was detected by a higher proportion of cells showing nuclear alterations and γ-H2AX expression. Our findings indicate that the source of ASCs can substantially influence their phenotype and therefore should be carefully considered in future cell therapies, avoiding, however, long-term culture to ensure genetic stability.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2024

Packaging “vegetable oils”: Insights into plant lipid droplet proteins

Abstract Plant neutral lipids, also known as “vegetable oils”, are synthesized within the endoplasmic reticulum (ER) membrane and packaged into subcellular compartments called lipid droplets (LDs) for stable storage in the cytoplasm. The biogenesis, modulation, and degradation of cytoplasmic LDs in plant cells are orchestrated by a variety of proteins localized to the ER, LDs, and peroxisomes. Recent studies of these LD-related proteins have greatly advanced our understanding of LDs not only as steady oil depots in seeds but also as dynamic cell organelles involved in numerous physiological processes in different tissues and developmental stages of plants. In the past 2 decades, technology advances in proteomics, transcriptomics, genome sequencing, cellular imaging and protein structural modeling have markedly expanded the inventory of LD-related proteins, provided unprecedented structural and functional insights into the protein machinery modulating LDs in plant cells, and shed new light on the functions of LDs in nonseed plant tissues as well as in unicellular algae. Here, we review critical advances in revealing new LD proteins in various plant tissues, point out structural and mechanistic insights into key proteins in LD biogenesis and dynamic modulation, and discuss future perspectives on bridging our knowledge gaps in plant LD biology.

Cai, Yingqi (ORCID:0000000203575809)↗
DOE OSTI2022

EDD Basic Stats and Graphs Notebook analysis (EDD BSG Notebook) v1.0

This jupyter notebook calculates basic statistics (e.g., mean, standard deviation, coefficient of variation) and simple graphs (e.g., bar graphs, line plots) for data from the Experiment Data Depot (EDD) to provide rapid and reproducible assessment of data quality to aid research efforts across the JBEI and ABF projects. It rapidly and reproducibly calculates basic statistical values for data stored in the EDD which aids researchers and strengthens comparisons across different experiments and projects.

Petzold, ChristopherJ↗
DOE OSTI2026

FleetREDI Insight: Intrastate Coach Bus Dataset

Capturing real-world data is critical to improving efficiency and supporting technology advancements in commercial vehicles. FleetREDI’s insights provide detailed duty cycle information and highlight unique aspects of the given dataset. Each insight delivers a quick look at the collected data by summarizing the operation and identifying key findings of the initial analysis. This FleetREDI insight explores coach buses operating in Colorado. Coach buses are a primary mover for intrastate transit and are primarily used for longer trips with more comfortable seats and a restroom. All Aboard America! Holdings Inc. offers various fixed-service and charter routes across Colorado on its Bustang fleet out of its depot in Golden, Colorado. NLR installed logging devices and collected operational data on nine 40-foot Bustang motorcoaches operating on fixed routes from May through August 2022. Using NLR’s FleetREDI data platform, this dataset provides a summary of daily operation to help understand duty cycle characteristics. This includes daily distance, fuel use, and estimated engine-produced energy consumption for nine motorcoaches that operated more than 33,000 miles. These vehicles primarily operated on Interstate 25 and Interstate 70. ![FleetREDI interstate bus](FleetREDI-interstate-bus.jpg)

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
DOE OSTI2020

Deep Direct-Use Geothermal Feasibility Study for Hawthorne NV

The Hawthorne Nevada, deep direct-use geothermal study is a two-year effort funded by the U.S. Department of Energy to determine the techno-economic feasibility of implementing a large-scale, direct-use facility for the Hawthorne Army Depot (HAD) and the public facilities of the city of Hawthorne and Mineral County. The approach links a production side analysis (PSA) and a demand side analysis (DSA) into a whole-system analysis (WSA) to provide an integrated assessment of the resource and the probability of delivering economically viable direct-use energy to Hawthorne. Hawthorne, Nevada is in the western part of the Basin and Range province and has been the focus of geothermal investigations for over 40 years. Over the last 15 years, several studies completed by the U.S. Navy Geothermal Program Office (GPO) in conjunction with industry professionals quantified the existence of several low temperature geothermal prospects, the most promising of which is called Prospect A. The promise of Prospect A is based on drilling and flow testing that produced ~100 °C water at flow rates of up to 31 l/s (500 gallons per minute). Measured productivity indexes range from 40-85 l/s/MPa, suggesting a warm and productive heat source. Despite the promise of the resource, uncertainties in its spatial extent and long-term sustainability mean that techno-economic analyses must include probabilities of the sustainability of the resource under different operating scenarios. Here, the PSA is conducted by integrating a wide range of disparate data to estimate lognormal P90, P50, and P10 resource capacities. These capacities are used as input to a thermal-hydrologic (T-H) model to estimate thermal drawdown for each capacity estimate for several different DSA scenarios. Using a systems-based approach, the WSA links the dynamic T-H simulations of the PSA/DSA combinations with the techno-economic model GEOPHIRES to account for both the temporal dynamics and uncertainties in the system to produce probabilistic distributions of several performance metrics including the levelized cost of heat (LCOH) and the return on investment (ROI). This report is the final delivery for the project and documents the study's activities and results.

15 GEOTHERMAL ENERGY↗
DOE OSTI2021

The Highly Integrated Vehicle Ecosystem (HIVE): A Platform for Managing the Operations of On-Demand Vehicle Fleets

This paper introduces the Highly Integrated Vehicle Ecosystem (HIVE), a transportation modeling tool developed by within the Center for Integrated Mobility Sciences (CIMS) group at the National Renewable Energy Laboratory (NREL). HIVE is an agent-based supply/demand model for Mobility on Demand (MoD) which mixes agent-based modeling and centralized dispatch for automated and human-driven fleets and ride hail passengers. Research questions using HIVE span multiple categories, including intelligent fleet planning (assessing fleet, battery, and infrastructure investment decisions), intelligent fleet control (charge management, vehicle dispatching) and strategic business model decision-making (depot-based full-time drivers versus gig-based drivers, human-driven versus automated). The components of the HIVE model are explained and then HIVE is demonstrated in a case study using demand data from the New York City Taxi & Limousine Commission data set.

33 ADVANCED PROPULSION SYSTEMS↗
DOE OSTI2021

Next Generation Logistics Systems for Delivering Optimal Biomass Feedstocks to Biorefining Industries in the Southeastern U.S.

The diverse portfolio of biomass sources that is available in the Southeastern U.S., including a significant supply of pine “residue”, represents a valuable strategic position for the region. Through blends formulated based on critical properties, this project will take full advantage of the range in biomass properties afforded by the portfolio to produce a consistent, high-performance feedstock for the industry, while lowering cost. Key developments being targeted to enable this potential include whole-tree transport to a state-of-the-art merchandising depot that will further access biomass from ongoing, forest industry operations. The approach will more effectively utilize the tree and distribute cost, while minimizing in-woods contamination of the woody biomass component. To implement this vision, information on the chemical composition and changes that are induced during multiple preprocessing steps (size reduction, moisture removal, densification, etc.) is needed. New NIR sensor technology will be developed for online monitoring of important biomass properties. The data will be incorporated into a statistical process control platform to improve process efficiency and meet required specifications. Advanced process models are being developed to inform the techno-economic and life-cycle assessment of the program’s impact. The new system will ultimately reduce operational risks from supply chain disruptions, and allow operation of larger-scale biorefineries.

09 BIOMASS FUELS↗
DOE OSTI2023

Agilent AgileBioFoundry CRADA (Final Report)

The mission of this CRADA with Agilent was to couple powerful MS platforms (QQQ, IM-QTOF-MS) with Agilent’s novel Ultra-High-Performance Liquid Chromatography (UHPLC) fast metabolomic workflows and perform ABF Machine Learning (ML) to generated datasets. Agilent transferred UHPLC methods to PNNL and LBNL and methods were implemented and demonstrated in both labs, achieving total acquisition times of < 10 min. Metabolites analyzed using Agilent’s shared methods included metabolites from central carbon metabolism, common across hosts, and metabolites unique to engineered strains. Standards were acquired in an UHPLC-Drift Tube Ion Mobility Mass Spectrometer (DTIMS) system for the first time within the context of ABF and methods were optimized based on Agilent’s protocols. Samples from ABF hosts Pseudomonas putida, Aspergillus pseudoterreus, Aspergillus niger and Rhodosporidium toruloides were analyzed using the UHPLC-DTIMS platform for a total of 276 runs. A data analysis workflow compatible with the Experimental Data Depot (EDD) and completely shareable was developed for the acquired UHPLC-DTIMS data. Samples were analyzed using a Data Independent Acquisition Approach (DIA), which for most of the standards provided more transitions therefore increasing detection confidence. Using the data acquired by PNNL, LBNL, and Agilent’s specifications from previous ML projects, SNL applied an ensemble ML strategy to pick the best performing model for automated LC-method selection. Finally, with the contribution of the participant labs and Agilent, SNL developed an Automated Method Selection (AMS) software tool to predict the best liquid chromatography method for analysis of any new molecules of interest. Samples with novel pathways and new metabolite targets of interest are generated at a high pace in the ABF. Therefore, our accomplishment in this CRADA improved the efficiency and accuracy of strain testing by developing and implementing fast analytical methods, robust processing tools, and software for predicting the best methods for UHPLC analysis.

97 MATHEMATICS AND COMPUTING↗