Results for “early formulation” — Page 9

DOE OSTI2026

Exposing and Reducing Biases of Simulating Mixed-Phase Clouds in the Convection-Permitting E3SM Atmosphere Model: Lessons From an Arctic Cold-Air Outbreak

Mixed-phase clouds modulate the water and energy cycles of high-latitude regions, yet their liquid-ice phase partitioning has long been poorly simulated in climate models. Here, simulations of Arctic mixed-phase clouds by the Simple Cloud-Resolving E3SM Atmosphere Model (SCREAM) are assessed against large-eddy simulations, satellite data, and ground-based observations during the Cold-Air Outbreaks in the Marine Boundary Layer Experiment field campaign. SCREAM simulates nearly completely frozen clouds, which is attributed largely to the unreasonably strong Wegener–Bergeron–Findeisen (WBF) process that converts liquid to ice excessively and partly to the early over-abundant ice production at cold temperatures from a temperature-deterministic deposition ice nucleation scheme. Assuming no subgrid variation for the WBF process in the original formulation particularly conflicts with the instantaneous saturation adjustment assumption in the condensation scheme that assumes subgrid variability, leading to exaggerated WBF process rates. A proposed simple physically-based improvement on the treatment of subgrid cloud overlap substantially increases supercooled liquid water content and notably improves cloud-top phase partitioning, aligning better with observations. Improvement of supercooled liquid water content also converges with increasing horizontal resolution. The deposition ice nucleation scheme is found responsible for a falsely-produced ice cloud aloft that is not observed, biasing the simulated cloud radiative effects and top-of-atmosphere radiative fluxes. This study identifies key deficiencies in cloud parameterizations that continue to challenge convection-permitting models.

Geosciences↗

DOE OSTI2022

A simple model of COVID-19 explains disease severity and the effect of treatments

Abstract Considerable effort has been made to better understand why some people suffer from severe COVID-19 while others remain asymptomatic. This has led to important clinical findings; people with severe COVID-19 generally experience persistently high levels of inflammation, slower viral load decay, display a dysregulated type-I interferon response, have less active natural killer cells and increased levels of neutrophil extracellular traps. How these findings are connected to the pathogenesis of COVID-19 remains unclear. We propose a mathematical model that sheds light on this issue by focusing on cells that trigger inflammation through molecular patterns: infected cells carrying pathogen-associated molecular patterns (PAMPs) and damaged cells producing damage-associated molecular patterns (DAMPs). The former signals the presence of pathogens while the latter signals danger such as hypoxia or lack of nutrients. Analyses show that SARS-CoV-2 infections can lead to a self-perpetuating feedback loop between DAMP expressing cells and inflammation, identifying the inability to quickly clear PAMPs and DAMPs as the main contributor to hyperinflammation. The model explains clinical findings and reveal conditions that can increase the likelihood of desired clinical outcome from treatment administration. In particular, the analysis suggest that antivirals need to be administered early during infection to have an impact on disease severity. The simplicity of the model and its high level of consistency with clinical findings motivate its use for the formulation of new treatment strategies.

60 APPLIED LIFE SCIENCES↗

DOE OSTI2022

Effect of the Nuclear Equation of State on Relativistic Turbulence-induced Core-collapse Supernovae

Abstract The nuclear equation of state (EOS) is an important component in the evolution of core-collapse supernovae. In this paper we make a survey of various EOSs in the literature and analyze their effect on spherical core-collapse models in which the effects of three-dimensional turbulence is modeled by a general relativistic formulation of Supernova Turbulence In Reduced-dimensionality (STIR). We show that the viability of the explosion is quite EOS dependent and that it best correlates with the early-time interior entropy density of the proto–neutron star. We check that this result is not progenitor dependent, although the lowest-mass progenitors show different explosion properties, due to the different pre-collapse nuclear composition. Larger central entropies also induce more vigorous proto–neutron star convection in our one-dimensional turbulence model, as well as a wider convective layer.

79 ASTRONOMY AND ASTROPHYSICS↗

NASA NTRS1988

Objective detection and forecasting of Clear-Air Turbulence (CAT): A status report

Clear-air turbulence has become the largest single cause of weather-related injuries occurring in commercial carriers at cruising altitudes. A technique for objective operational CAT detection (the SCATR index) has been formulated. Its physical basis ties CAT to total energy dissipation as a response to meso- and synoptic-scale dynamical processes associated with upper-level jet stream/frontal zones. Early case studies using properly analyzed routine RAOB rawinsonde sounding data have shown promise.

Keller, John L.↗

NASA NTRS1986

Spaceborne Imaging Radar Project

In June of 1985 the Project Initiation Agreement was signed by the Jet Propulsion Laboratory and the NASA Office of Space Science and Applications for the Spaceborne Imaging Radar Project (SIR). The thrust of the Spaceborne Imaging Radar Project is to continue the evolution of synthetic aperture radar (SAR) science and technology developed during SEASAT, SIR-A and SIR-B missions to meet the needs of the Earth Observing System (EOS) in the mid 1990's. As originally formulated, the Project plans were for a reflight of the SIR-B in 1987, the development of a new SAR, SIR-C, for missions in mid 1989 and early 1990, and the upgrade of SIR-C to EOS configuration with a qualification flight aboard the shuttle in the 1993 time frame (SIR-D). However, the loss of the shuttle Challenger has delayed the first manifest for SIR to early 1990. This delay prompted the decision to drop SIR-B reflight plans and move ahead with SIR-C to more effectively utilize this first mission opportunity. The planning for this project is discussed.

Herman, Neil↗

NASA NTRS1983

Prebiotic organic syntheses and the origin of life

The outline of a modern paradigm for the origins of life on earth was first formulated by Oparin (1924). According to the considered hypothesis, living organisms arose naturally on the primitive earth through a lengthy process of chemical evolution of organic matter which began in the atmosphere and culminated in the primordial seas. Details regarding the chemical evolution paradigm are discussed, and chemical evolutionary processes formulated by principal contributors are reviewed in a historical context. Attention is given to the Oparin model of the prebiotic earth, the Urey model, the Rubey model, a multistage model for early atmospheric evolution, and other variations on the theme of prebiotic atmospheres. Evidence in support of the chemical evolution paradigm is considered along with modern models regarding the accretion of earth and the formation of its core, and problems and prospects for future studies.

Chang, S.↗

NASA NTRS2000

Comparative Study in Laboratory Rats to Validate Sperm Quality Methods and Endpoints

Abstract The Naval Health Research Center, Detachment (Toxicology) performs toxicity studies in laboratory animals to characterize the risk of exposure to chemicals of Navy interest. Research was conducted at the Toxicology Detachment at WPAFB, OH in collaboration with Wright State University, Department of Biological Sciences for the validation of new bioassay methods for evaluating reproductive toxicity. The Hamilton Thorne sperm analyzer was used to evaluate sperm damage produced by exposure to a known testicular toxic agent, methoxyacetic acid and by inhalation exposure to JP-8 and JP-5 in laboratory rats. Sperm quality parameters were evaluated (sperm concentration, motility, and morphology) to provide evidence of sperm damage. The Hamilton Thorne sperm analyzer utilizes a DNA specific fluorescent stain (similar to flow cytometry) and digitized optical computer analysis to detect sperm cell damage. The computer assisted sperm analysis (CASA) is a more rapid, robust, predictive and sensitive method for characterizing reproductive toxicity. The results presented in this poster report validation information showing exposure to methoxyacetic acid causes reproductive toxicity and inhalation exposure to JP-8 and JP-5 had no significant effects. The CASA method detects early changes that result in reproductive deficits and these data will be used in a continuing program to characterize the toxicity of chemicals, and combinations of chemicals, of military interest to formulate permissible exposure limits.

Price, W. A.↗

NASA NTRSDate not supplied

NASA CARA Prelaunch Analysis and Process

NASA implemented an official Procedural Requirement (NPR) 8079.1 in June 2023, establishing the minimum collision avoidance requirements and associated operational protocols for NASA space flight programs, projects, and spacecraft to protect the space environment by reducing the risk of collision to an acceptable level. Part of the requirement employs a two-fold approach to analyze the satellite design process with conjunction assessment and risk mitigation in mind, during the pre-launch process, led by the Conjunction Assessment Risk Analysis (CARA) Program for non-Human Space Flight (HSF) Missions. This presentation outlines CARA coordination with missions, informed by the NPR, that spans early mission development to operations. CARA is an Agency-level resource that provides support to all NASA non-HSF missions. CARA protects the orbital environment from collision between NASA non-HSF missions and other tracked on-orbit objects. During the pre-formulation and formulation phases, NASA missions undergo a series of conjunction assessment analyses captured in the Orbital Collision Avoidance Plan (OCAP) prior to transitioning to the implementation phase (typically at the Preliminary Design Review (PDR) or equivalent). The OCAP analyses consist of a thorough review of the spacecraft(s) orbit selection and placement, deployment, cataloguing performance, trackability, ephemeris generation, conjunction mitigation options, autonomous maneuvering, and risk assessment parameters which are performed by a dedicated CARA Analysis Team. The results of these analyses, CARA’s formal recommendations, and the mission’s methods for implementing them, are documented in the OCAP. The intent of engaging in this process so early in the mission design phase, is to ensure that conjunction assessment is considered from the outset, thus mitigating costly design changes and operational risks down the road. NASA missions are also required to coordinate their operational processes and conjunction mitigation procedures with CARA in a Conjunction Assessment Operations Implementation Agreement (CAOIA). The aim of this process is to document the conjunction assessment screening process, conjunction risk assessment parameters, conjunction mitigation steps, flight dynamics operations concepts and maneuvers, and the communication and coordination process between the mission’s project manager and CARA. The intent of the CAOIA document is for it to be completed iteratively, and as missions update these elements, corresponding changes are made in the CAOIA. With this process in place, the engagement and coordination between the missions and CARA from early in the design process into mission operations, helps to ensure that missions not only have a robust conjunction assessment concept of operations to reduce conjunction risk for space sustainability, but are also able to achieve their science goals and have a successful mission.

conjunction assessment↗

NASA NTRSDate not supplied

NASA CARA Prelaunch Analysis and Process

NASA implemented an official Procedural Requirement (NPR) 8079.1 in June 2023, establishing the minimum collision avoidance requirements and associated operational protocols for NASA space flight programs, projects, and spacecraft to protect the space environment by reducing the risk of collision to an acceptable level. Part of the requirement employs a two-fold approach to analyze the satellite design process with conjunction assessment and risk mitigation in mind, during the pre-launch process, led by the Conjunction Assessment Risk Analysis (CARA) Program for non-Human Space Flight (HSF) Missions. This presentation outlines CARA coordination with missions, informed by the NPR, that spans early mission development to operations. CARA is an Agency-level resource that provides support to all NASA non-HSF missions. CARA protects the orbital environment from collision between NASA non-HSF missions and other tracked on-orbit objects. During the pre-formulation and formulation phases, NASA missions undergo a series of conjunction assessment analyses captured in the Orbital Collision Avoidance Plan (OCAP) prior to transitioning to the implementation phase (typically at the Preliminary Design Review (PDR) or equivalent). The OCAP analyses consist of a thorough review of the spacecraft(s) orbit selection and placement, deployment, cataloguing performance, trackability, ephemeris generation, conjunction mitigation options, autonomous maneuvering, and risk assessment parameters which are performed by a dedicated CARA Analysis Team. The results of these analyses, CARA’s formal recommendations, and the mission’s methods for implementing them, are documented in the OCAP. The intent of engaging in this process so early in the mission design phase, is to ensure that conjunction assessment is considered from the outset, thus mitigating costly design changes and operational risks down the road. NASA missions are also required to coordinate their operational processes and conjunction mitigation procedures with CARA in a Conjunction Assessment Operations Implementation Agreement (CAOIA). The aim of this process is to document the conjunction assessment screening process, conjunction risk assessment parameters, conjunction mitigation steps, flight dynamics operations concepts and maneuvers, and the communication and coordination process between the mission’s project manager and CARA. The intent of the CAOIA document is for it to be completed iteratively, and as missions update these elements, corresponding changes are made in the CAOIA. With this process in place, the engagement and coordination between the missions and CARA from early in the design process into mission operations, helps to ensure that missions not only have a robust conjunction assessment concept of operations to reduce conjunction risk for space sustainability, but are also able to achieve their science goals and have a successful mission.

conjunction assessment↗

DOE OSTI2025

Predicting Si-Anode Calendar Life Using Machine Learning: Correlating Electrolyte Properties and Electrochemical Signals

This study evaluates novel electrolytes tailored for Si-containing anodes to promote calendar-life. Drawing inspiration from advancements in electrolytes for Li-metal cells, the work investigates correlations between predicted electrolyte properties and measured electrochemical performance using several machine-learning models. By leveraging machine learning and advanced modeling techniques, this study aims to establish predictive frameworks that accelerate calendar-aging experiments and inform rational electrolyte design for Si-containing cells. In the present study, fifteen different electrolytes are evaluated in a Si-containing cell using an accelerated calendar-life protocol. For each electrolyte considered, 87 properties (features) from the Advanced Electrolyte Model were produced to identify key property/performance relationships. In this study, the best performing electrolytes were generally those formulations that included non-coordinating fluoroether solvents, and the most predictive features for long-term calendar-life were features related to salt concentration and electrolyte viscosity as well as early capacity, ionic conductivity, and Coulombic efficiency measurements. The framework developed in this study correlating electrolyte properties to measured electrochemical performance is expected to accelerate electrolyte design for Si-containing anodes and ultimately enable high-energy-density, long-life Li-ion batteries.

25 - ENERGY STORAGE↗

NASA NTRS1997

Automation for Air Traffic Control: The Rise of a New Discipline

The current debate over the concept of Free Flight has renewed interest in automated conflict detection and resolution in the enroute airspace. An essential requirement for effective conflict detection is accurate prediction of trajectories. Trajectory prediction is, however, an inexact process which accumulates errors that grow in proportion to the length of the prediction time interval. Using a model of prediction errors for the trajectory predictor incorporated in the Center-TRACON Automation System (CTAS), a computationally fast algorithm for computing conflict probability has been derived. Furthermore, a method of conflict resolution has been formulated that minimizes the average cost of resolution, when cost is defined as the increment in airline operating costs incurred in flying the resolution maneuver. The method optimizes the trade off between early resolution at lower maneuver costs but higher prediction error on the one hand and late resolution with higher maneuver costs but lower prediction errors on the other. The method determines both the time to initiate the resolution maneuver as well as the characteristics of the resolution trajectory so as to minimize the cost of the resolution. Several computational examples relevant to the design of a conflict probe that can support user-preferred trajectories in the enroute airspace will be presented.

Erzberger, Heinz↗

NASA NTRS2003

Propulsion Ground Testing: Planning for the Future

Advanced planners are constantly being asked to plan for the provision of future test capability. Historically, this capability is provided either by substantial investment in new test facility capabilities, or in the substantial investment in the modification of pre-exiting test facilities. The key words in the previous sentence are 'substantial investment.' In the evolving environment of increasingly constrained resources, how is an advanced planner to plan for the provisions of such capabilities? Additionally, the conundrum exists that program formulation decisions are being made based on both life cycle cost decisions in an environment in which the more immediate challenge of front-end capital investment oftentimes is the linchpin upon which early decisions are made. In such an environment, how are plans and decisions made? This paper cites examples of decisions made in the past in the area of both major test facility upgrades, as well as major new test facility investment.

Bruce, Robert↗

NASA NTRS2008

The LISA Project at NASA

Although officially in early Phase A, LISA is currently classified as "under-study" at NASA. It has a very high recommendation from the 2000 decadal survey. and has received strong endorsements at all reviews. Mission formulation and technology development continue at modest levels. The Project is starting preparations for the next decadal survey, expected to commence in 2009.

Stebbins, Robin T.↗

NASA NTRS1978

Vector space methods of photometric analysis - Applications to O stars and interstellar reddening

A multivariate vector-space formulation of photometry is developed which accounts for error propagation. An analysis of uvby and H-beta photometry of O stars is presented, with attention given to observational errors, reddening, general uvby photometry, early stars, and models of O stars. The number of observable parameters in O-star continua is investigated, the way these quantities compare with model-atmosphere predictions is considered, and an interstellar reddening law is derived. It is suggested that photospheric expansion affects the formation of the continuum in at least some O stars.

Massa, D.↗

NASA NTRS1987

LEO and GEO missions

The occurrence of the Challenger disaster in early 1986 caused a severe reevaluation of the space program. Plans already established had to be drastically revised and new plans had to be made. NASA created the Space Leadership Planning Group (SLPG) to formulate space mission plans covering a 50 year period based on Agency goals and objectives responsive to the National Commission on Space recommendations. An interim view of the status of SLPG plans for low altitude and geosynchronous missions is presented.

Mercanti, Enrico↗

NASA NTRS1993

A hybrid finite element-boundary integral for the analysis of cavity-backed antennas of arbitrary shape

This is the final report on this project which was concerned with the analysis of cavity-backed antennas and more specifically spiral antennas. The project was a continuation of a previous analysis, which employed rectangular brick elements, and was, thus, restricted to planar rectangular patch antennas. A total of five reports were submitted under this project and we expect that at least four journal papers will result from the research described in these reports. The abstracts of the four previous reports are included. The first of the reports (028918-1-T) is over 75 pages and describes the general formulation using tetrahedral elements and the computer program. Report 028918-2-T was written after the completion of the computer program and reviews the capability of the analysis and associated software for planar circular rectangular patches and for a rectangular planar spiral. Measurements were also done at the University of Michigan and at Mission Research Corp. for the purpose of validating the software. We are pleased to acknowledge a partial support from Mission Research Corp. in carrying out the work described in this report. The third report (028918-3-T) describes the formulation and partial validation (using 2D data) for patch antennas on a circular platform. The 3D validation and development of the formulation for patch antennas on circular platforms is still in progress. The fourth report (028918-4-T) is basically an invited journal paper which will appear in the 'J. Electromagnetic Waves and Applications' in early 1994. It describes the application of the finite element method in electromagnetics and is primarily based on our work here at U-M. This final report describes the culmination of our efforts in characterizing complex cavity-backed antennas on planar platforms. The report describes for the first time the analysis of non-planar spirals and non-rectangular slot antennas as well as traditional planar patch antennas. The comparisons between measurements and calculations are truly impressive. Another unique aspect of this work is the incorporation of the FFT as part of the BiCG solver by overlaying a structured triangular mesh over the unstructured mesh. The implementation of this BiCG-FFT solution algorithm is important in minimizing the CPU and storage requirements. This final report will be submitted for publication in a refereed journal.

Gong, Jian↗

NASA NTRS2005

Bayesian Analysis of the Power Spectrum of the Cosmic Microwave Background

There is a wealth of cosmological information encoded in the spatial power spectrum of temperature anisotropies of the cosmic microwave background. The sky, when viewed in the microwave, is very uniform, with a nearly perfect blackbody spectrum at 2.7 degrees. Very small amplitude brightness fluctuations (to one part in a million!!) trace small density perturbations in the early universe (roughly 300,000 years after the Big Bang), which later grow through gravitational instability to the large-scale structure seen in redshift surveys... In this talk, I will discuss a Bayesian formulation of this problem; discuss a Gibbs sampling approach to numerically sampling from the Bayesian posterior, and the application of this approach to the first-year data from the Wilkinson Microwave Anisotropy Probe. I will also comment on recent algorithmic developments for this approach to be tractable for the even more massive data set to be returned from the Planck satellite.

Bayesian inference↗

DOE OSTI2025

Fluid modeling of low-temperature plasmas

Fluid models are essential for understanding and predicting low-temperature plasma (LTP) behavior in various scientific and industrial settings. This paper provides an introductory tutorial on fluid modeling of LTPs, covering model formulation, implementation, and computational simulations. The tutorial focuses on five main components of the formulation of LTP fluid models: fluid flow, energy, chemistry, electromagnetism, and material properties, as well as in essential aspects of model implementations, including multiscale phenomena, multiphysics coupling, and numerical convergence. Designed for students and early-career researchers, this work offers a practical foundation for developing and using fluid models, from in-house computational codes to commercial software, bridging fundamental theory with real-world applications.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗