Contributions of the space program to our knowledge of motion sickness.
A slow rotation room (SRR) was used in a laboratory setting to study experimental motion sickness. This SRR simulates, to some degree, the conditions on a rotating spacecraft. Habitability of the chamber was ascertained by subjects who remained in the room for over a month with experimenters in attendance. Control over stressful accelerations involved regulation of the room's angular velocity and the subject's head rotations. By standardizing the head rotations, the strength of the disturbing stimulus became a function of the room's angular velocity. Mild acute episodes of motion sickness were readily kept under control. Certain techniques demonstrated that a subject's susceptibility may be expressed in terms of the number of head motions at a particular angular velocity to reach a chosen endpoint. Investigations using prolonged exposure used rapid increase in rpm to terminal velocity to evoke symptoms, or incremental increase to terminal velocity to prevent them. The effectiveness of 16 representative antimotion sickness drugs is discussed.