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At least 1,621 records · Page 90

Acoustic waveguiding in a silicon carbide phononic crystals at microwave frequencies

Two dimensional SiC–air phononic crystals have been modeled, fabricated, and tested with a measured bandgap ranging from 665 to 693 MHz. Snowflake air inclusions on a hexagonal lattice were used for the phononic crystal. By manipulating the phononic crystal lattice and inserting circular inclusions, a waveguide was created at 680 MHz. The combined insertion loss and propagation loss for the waveguide is 8.2 dB, i.e., 39% of the energy is guided due to the high level of the confinement afforded by the phononic crystal. In conclusion, the SiC–air phononic crystals and waveguides were fabricated using a CMOS-compatible process, which allows for seamless integration of these devices into wireless communication systems operating at microwave frequencies.

42 ENGINEERING↗

Inhomogeneous barrier heights at dipole-controlled SrRuO 3 /Nb:SrTiO 3 Schottky junctions

It has recently been shown that the Schottky barrier height (SBH) formed at metal-semiconductor perovskite oxide heterojunctions can be dramatically tuned by the insertion of atomic-scale dipole layers at the interface. However, in idealized form, this would only allow for specific values of the SBH, discretized by the dipole layer thickness. We examine the effect of fractional unit cell LaAlO 3 dipoles inserted between SrRuO 3 and Nb:SrTiO 3 in (001) Schottky junctions, as a function of their in-plane lateral distribution. When the LaAlO 3 dipoles are finely dispersed, we observe uniformly rectifying junctions, with SBHs reflecting the fractional LaAlO 3 coverage. For larger length-scale distributions, the junction characteristics reflect the inhomogeneous combination of regions with and without the interface dipole. The characteristic length scale dividing the two regimes corresponds to the semiconductor depletion width scaled by the dipole potential, determining the effective scale for which the SBH can be continuously tuned.

36 MATERIALS SCIENCE↗

Overlap junctions for superconducting quantum electronics and amplifiers

Due to their unique properties as lossless, nonlinear circuit elements, Josephson junctions lie at the heart of superconducting quantum information processing. Previously, we demonstrated a two-layer, submicrometer-scale overlap junction fabrication process suitable for qubits with long coherence times. Here, we extend the overlap junction fabrication process to micrometer-scale junctions. This allows us to fabricate other superconducting quantum devices. For example, we demonstrate an overlap junction-based Josephson parametric amplifier that uses only two layers. This efficient fabrication process yields frequency-tunable devices with negligible insertion loss, a gain of ∼30 dB, and quantum limited noise performance. Compared to other processes, the overlap junction allows for fabrication with minimal infrastructure, high yield, and state-of-the-art device performance.

Bal, Mustafa (ORCID:0000000307516774)↗

Dark matter axion search using a Josephson Traveling wave parametric amplifier

Here, we describe the first implementation of a Josephson Traveling Wave Parametric Amplifier (JTWPA) in an axion dark matter search. The operation of the JTWPA for a period of about two weeks achieved sensitivity to axion-like particle dark matter with axion–photon couplings above 10 -13 Ge V -1 over a narrow range of axion masses centered around 19.84 µeV by tuning the resonant frequency of the cavity over the frequency range of 4796.7–4799.5 MHz. The JTWPA was operated in the insert of the axion dark matter experiment as part of an independent receiver chain that was attached to a 0.56-l cavity. The ability of the JTWPA to deliver high gain over a wide (3 GHz) bandwidth has engendered interest from those aiming to perform broadband axion searches, a longstanding goal in this field.

47 OTHER INSTRUMENTATION↗

Design of AlGaN-Zn(Si,Ge)N2 quantum wells for high-efficiency ultraviolet light emitters

The effect of inserting a nm-scale layer of Zn(Si,Ge)N2 into an AlGaN quantum well structure designed for light emission in the wavelength range from 255 to 305 nm is investigated here. The enhanced confinement of the hole within the quantum well results in an enhancement of the overlap of the hole and electron wave functions, resulting in an enhancement of the radiative recombination rate. In this theoretical calculation, for emission at a 270 nm wavelength, the enhancement in the wavefunction overlap can reach a factor of 7 when compared to an AlGaN quantum well device specifically engineered for optimal emission at the identical wavelength. Increases of almost an order of magnitude in both the peak spontaneous emission intensity and the radiative recombination rate are predicted. The peak emission wavelength can be tuned from 255 to 305 nm by adjusting the width and/or the composition of the inserted layer. The proposed structures provide a route to higher efficiency ultraviolet practical light emitting diodes and lasers.

Physics↗

Transmission spectra of a double-clad fibre structure under bending

We have studied a fibre-optic structure whose operation relies on conversion of core and cladding modes that are coupled across the interface between two fibres differing in refractive index profile. The structure contains a section of an SM630 double-clad, small-core, single-mode fibre inserted between two SMF-28 standard fibres. We have measured the transmission spectrum of the structure when the SM630 fibre was bent and analysed the mode structure of the double-clad fibre and the origin of dips in its transmission spectrum. The resonance dips have been found to shift to longer wavelengths with increasing fibre curvature. We have evaluated the shift as a function of the length of the inserted fibre, its bend direction and the nature of the input fibre. (fiber optics)

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Cas9-mediated genome editing in the methanogenic archaeon Methanosarcina acetivorans

Although Cas9-mediated genome editing has proven to be a powerful genetic tool in eukaryotes, its application in Bacteria has been limited because of inefficient targeting or repair; and its application to Archaea has yet to be reported. Here we describe the development of a Cas9-mediated genome-editing tool that allows facile genetic manipulation of the slow-growing methanogenic archaeon Methanosarcina acetivorans . Introduction of both insertions and deletions by homology-directed repair was remarkably efficient and precise, occurring at a frequency of approximately 20% relative to the transformation efficiency, with the desired mutation being found in essentially all transformants examined. Off-target activity was not observed. We also observed that multiple single-guide RNAs could be expressed in the same transcript, reducing the size of mutagenic plasmids and simultaneously simplifying their design. Cas9-mediated genome editing reduces the time needed to construct mutants by more than half (3 vs. 8 wk) and allows simultaneous construction of double mutants with high efficiency, exponentially decreasing the time needed for complex strain constructions. Furthermore, coexpression the nonhomologous end-joining (NHEJ) machinery from the closely related archaeon, Methanocella paludicola , allowed efficient Cas9-mediated genome editing without the need for a repair template. The NHEJ-dependent mutations included deletions ranging from 75 to 2.7 kb in length, most of which appear to have occurred at regions of naturally occurring microhomology. The combination of homology-directed repair-dependent and NHEJ-dependent genome-editing tools comprises a powerful genetic system that enables facile insertion and deletion of genes, rational modification of gene expression, and testing of gene essentiality.

59 BASIC BIOLOGICAL SCIENCES↗

Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X

USP9X is a conserved deubiquitinase (DUB) that regulates multiple cellular processes. Dysregulation of USP9X has been linked to cancers and X-linked intellectual disability. Here, we report the crystal structure of the USP9X catalytic domain at 2.5-Å resolution. The structure reveals a canonical USP-fold comprised of fingers, palm, and thumb subdomains, as well as an unusual β-hairpin insertion. The catalytic triad of USP9X is aligned in an active configuration. USP9X is exclusively active against ubiquitin (Ub) but not Ub-like modifiers. Cleavage assays with di-, tri-, and tetraUb chains show that the USP9X catalytic domain has a clear preference for K11-, followed by K63-, K48-, and K6-linked polyUb chains. Using a set of activity-based diUb and triUb probes (ABPs), we demonstrate that the USP9X catalytic domain has an exo-cleavage preference for K48- and endo-cleavage preference for K11-linked polyUb chains. The structure model and biochemical data suggest that the USP9X catalytic domain harbors three Ub binding sites, and a zinc finger in the fingers subdomain and the β-hairpin insertion both play important roles in polyUb chain processing and linkage specificity. Furthermore, unexpected labeling of a secondary, noncatalytic cysteine located on a blocking loop adjacent to the catalytic site by K11-diUb ABP implicates a previously unreported mechanism of polyUb chain recognition. The structural features of USP9X revealed in our study are critical for understanding its DUB activity. The new Ub-based ABPs form a set of valuable tools to understand polyUb chain processing by the cysteine protease class of DUBs.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

A comprehensive genomic scan reveals gene dosage balance impacts on quantitative traits in Populus trees

Gene dosage variation and the associated changes in gene expression influence a wide variety of traits, ranging from cancer in humans to yield in plants. It is also expected to affect important traits of ecological and agronomic importance in forest trees, but this variation has not been systematically characterized or exploited. Here we performed a comprehensive scan of the Populus genome for dosage-sensitive loci affecting quantitative trait variation for spring and fall phenology and biomass production. The study population was a large collection of clonally propagated F1 hybrid lines of Populus that saturate the genome 10-fold with deletions and insertions (indels) of known sizes and positions. As a group, the phenotypic means of the indel lines consistently differed from control nonindel lines, with an overall negative effect of both insertions and deletions on all biomass-related traits but more diverse effects and an overall wider phenotypic distribution of the indel lines for the phenology-related traits. We also investigated the correlation between gene dosage at specific chromosomal locations and phenotype, to identify dosage quantitative trait loci (dQTL). Such dQTL were detected for most phenotypes examined, but stronger effect dQTL were identified for the phenology-related traits than for the biomass traits. Furthermore our genome-wide screen for dosage sensitivity in a higher eukaryote demonstrates the importance of global genomic balance and the impact of dosage on life history traits.

09 BIOMASS FUELS↗

Pseudouridine synthase 7 is an opportunistic enzyme that binds and modifies substrates with diverse sequences and structures

Pseudouridine (Ψ) is a ubiquitous RNA modification incorporated by pseudouridine synthase (Pus) enzymes into hundreds of noncoding and protein-coding RNA substrates. Here, in this study, we determined the contributions of substrate structure and protein sequence to binding and catalysis by pseudouridine synthase 7 (Pus7), one of the principal messenger RNA (mRNA) modifying enzymes. Pus7 is distinct among the eukaryotic Pus proteins because it modifies a wider variety of substrates and shares limited homology with other Pus family members. We solved the crystal structure of Saccharomyces cerevisiae Pus7, detailing the architecture of the eukaryotic-specific insertions thought to be responsible for the expanded substrate scope of Pus7. Additionally, we identified an insertion domain in the protein that fine-tunes Pus7 activity both in vitro and in cells. These data demonstrate that Pus7 preferentially binds substrates possessing the previously identified UGUAR (R = purine) consensus sequence and that RNA secondary structure is not a strong requirement for Pus7-binding. In contrast, the rate constants and extent of Ψ incorporation are more influenced by RNA structure, with Pus7 modifying UGUAR sequences in less-structured contexts more efficiently both in vitro and in cells. Although less-structured substrates were preferred, Pus7 fully modified every transfer RNA, mRNA, and nonnatural RNA containing the consensus recognition sequence that we tested. Our findings suggest that Pus7 is a promiscuous enzyme and lead us to propose that factors beyond inherent enzyme properties (e.g., enzyme localization, RNA structure, and competition with other RNA-binding proteins) largely dictate Pus7 substrate selection.

59 BASIC BIOLOGICAL SCIENCES↗

Computational Thermal Hydraulics of a High-Performance Low-Enriched-Uranium Annular Target for HFIR Irradiation

Molybdenum-99 has historically been generated via isolation from fissioned highly enriched uranium (HEU) targets. Here, this isotope is in high demand due to its daily use across the world in radiopharmaceutical medical procedures. The primary objective of this work was to design and analyze an experimental target assembly containing one low-enriched-uranium (LEU) annular target for irradiation at the High Flux Isotope Reactor (HFIR). Efforts included incorporating spatially dependent energy sources from neutron and gamma interactions, quantifying thermal contact conductance at material interfaces, performing grid-independent studies, comparing turbulence models, and simulating various steady-state and transient scenarios relevant for irradiation qualification and eventual insertion. These models provide velocity, pressure, and temperature distributions in both space and time. Such results enable the selection of an appropriate irradiation location, fission rate density, and flow-limiting orifice size and demonstrate compliance with HFIR safety requirements such that insertion into the reactor can be approved. This analysis shows that across all scenarios, wetted surface temperatures remain below the coolant saturation temperature with no net vapor formation in the coolant. In every scenario, all components stay below 30% of the aluminum 6061 melting temperature. Computational fluid dynamics and system-level models predict peak target temperatures that agree within 4%, though the predicted axial location of the peak differs by about 10% of the heated length due to differences in flow development length. These results de-risk the irradiation of LEU (annular targets) and strengthen a domestic, HEU-independent 99 Mo supply by providing important fuel performance data to form the foundation for a robust licensing basis.

Molybdenum-99↗

Concept Descriptions for the VTR Rabbit System and Driver Fuel Test Assemblies

Two of the experiment vehicles being developed for the Versatile Test Reactor (VTR) are presented here. The first is a rabbit system that will enable rapid insertion of small test capsules into the high fast flux of the VTR core for relatively short durations. The rabbit concept development includes the construction/demonstration of a near-full-scale system in a deep-water pool to demonstrate functionality, development of a concept of operations and initial procedures, and validation of thermal-hydraulic modeling. In addition, modeling efforts are underway to simulate the thermal and neutronic environment of a rabbit capsule. The second type of experiment vehicle presented here is a driver fuel test assembly for inserting fuel and materials tests into the core by replacing a driver fuel assembly. Here, a novel design for dismountable test assemblies is proposed for the VTR.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Evaluation of Direct Drive Capsule Fill-Tube Assembly Survivability in Support of the 100 GBar Campaign

Capsule fill-tube target assemblies (CFTAs) for direct-drive have been demonstrated in the past for Laser for Laboratory Energetics (LLE) cryogenic layering studies, evolving and building upon successful deliveries for NIF. The current 100 GigaBar (GBar) campaign requires increased tolerances over prior CFTA work in terms of robustness, cleanliness, reduced fill tube diameter and glue size. To tackle these challenges, GA and LLE are developing a direct drive CFTA that survives all fabrication activities, from assembly, qualification testing and transport to cryogenic layering and target chamber insertion at the OMEGA laser facility. Approximately 55 CFTAs of two main designs have been constructed and tested to date, building off the current LLE cryogenic layering study CFTA design (typically 870 µm diameter x 25 µm thick wall capsule). Variations of glass fill tubes sizes from 30, 20 and 10 µm diameter, which are inserted and glued into the capsule. Testing protocols were developed to enable comparison of different designs against one another and evaluate their robustness at room temperature. The testing protocols include pressure checks, resonant vibration mode sweeps, runout and vibration testing to a power spectral density (PSD) input. In this paper we will compare the different design tradeoffs, measurements and results including glue fillets, sag of the fill tubes under gravity, runout and hysteresis, ringdown response, X-ray imaging of the pipette wall thicknesses, and scanning electron microscope (SEM) images taken of failed fill tubes and glue joints. Assessment of the modal vibration modeling for the designs will be compared against the vibration data. Lastly, a design recommendation is put forth meeting the design constraints, which consists of a polymicro composite tube and 10 µm fill tube, ensuring survivability at cryogenic temperatue, a higher first mode resonance and smaller fuel volume.

100 GBar↗

Soft particles and infinite-dimensional geometry

Abstract In the sigma model, soft insertions of moduli scalars enact parallel transport ofS-matrix elements about the finite-dimensional moduli space of vacua, and the antisymmetric double-soft theorem calculates the curvature of the vacuum manifold. We explore the analogs of these statements in gauge theory and gravity in asymptotically flat spacetimes, where the relevant moduli spaces are infinite-dimensional. These models have spaces of vacua parameterized by (trivial) flat connections on the celestial sphere, and soft insertions of photons, gluons, and gravitons parallel transportS-matrix elements about these infinite-dimensional manifolds. We argue that the antisymmetric double-soft gluon theorem ind + 2 bulk dimensions computes the curvature of a connection on the infinite-dimensional space Map ( S d , G ) / G , whereGis the global part of the gauge group. The analogous metrics in abelian gauge theory and gravity are flat, as indicated by the vanishing of the antisymmetric double-soft theorems in those models. In other words, Feynman diagram calculations not only know about the vacuum manifold of Yang–Mills theory, they can also be used to compute its curvature. The results have interesting implications for flat space holography.

Astronomy & Astrophysics↗

Magnetic and Mechanical Analysis of Bi-2212 Rutherford Cable in a Cos-Theta Sub-Scale Dipole Coil

The U.S. Magnet Development Program (US-MDP) explores high-field accelerator magnets compatible with operational conditions beyond the limits of Nb$_3$Sn technology. The ongoing R&D High-Temperature Superconductors (HTS) suggests using Bi$_2$Sr$_2$CaCu$_2$O$_{8-x}$ (Bi-2212) as superconducting element. Bi-2212 Rutherford cables maintain a high critical current (I$_C$) when exposed to a large external magnetic field. However, Bi-2212 exhibits an oversensitive stress-strain response when subject to large Lorentz forces. This paper reports on the magnetic and mechanical analysis of the Bi-2212 cosine-theta insert being developed at Fermilab for a hybrid magnet composed of two external layers of Nb$_3$Sn and two internal layers of Bi-2212. We performed a FEM analysis of the insert to estimate the HTS stress state in the coil's strands under magnetic and mechanical loads.

43 PARTICLE ACCELERATORS↗

Tungsten erosion by unipolar arcing in DIII-D

Here, unipolar arcing was an important mechanism of metal surface erosion during the recently conducted Metal Rings Campaign in DIII-D when two toroidally continuous tile rings with 5 cm wide W-coated TZM inserts were installed in graphite tiles in the lower divertor, one on the floor and one on the shelf. Most of the arc damage occurred on the shelf ring. The total amount of W removed by arcing from the affected ~4% of the shelf ring area was estimated ~0.8 × 10 21 at., about half of the total amount of W eroded and redeposited outside the inserts (1.8 ± 0.9)×10 21 at. The rings were exposed for a total of ~480 discharges, an equivalent of plasma time on W surfaces (with ${{I}}_{{\rm{p}}}\gt 0.5$ MA) ~10 3 s. Arcing was monitored in situ with WI (400.9 nm) filtered camera and photomultipliers and showed that: (i) arcing only occurred during ELMs and disruptions, (ii) arcing rate was much lower on the floor than on the shelf ring, and (iii) arcing had a low cut off power flux density about 2 MW m –2 . About half of arc tracks had large ${10}^{\circ }$ pitch angle and probably were produced during disruptions. Such tracks were only found on the shelf. Moderate toroidal variation of the arc track density and W erosion with nearly n = 1 pattern has been measured.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Standard Model thermodynamics across the electroweak crossover

Even though the Standard Model with a Higgs mass m{sub \tiny H}=125 GeV possesses no bulk phase transition, its thermodynamics still experiences a “soft point” at temperatures around T=160 GeV, with a deviation from ideal gas thermodynamics. Such a deviation may have an effect on precision computations of weakly interacting dark matter relic abundances if their mass is in the few TeV range, or on leptogenesis scenarios operating in this temperature range. By making use of results from lattice simulations based on a dimensionally reduced effective field theory, we estimate the relevant thermodynamic functions across the crossover. The results are tabulated in a numerical form permitting for their insertion as a background equation of state into cosmological particle production/decoupling codes. We find that Higgs dynamics induces a non-trivial “structure” visible e.g. in the heat capacity, but that in general the largest radiative corrections originate from QCD effects, reducing the energy density by a couple of percent from the free value even at T>160 GeV.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Results from an improved flowing liquid lithium limiter with increased flow uniformity in high power plasmas in EAST

Significant engineering and physic progress was made by the upgrade of a flowing liquid lithium limiter (FLiLi) inserted into EAST H-mode discharges in 2016. The progress includes an improvement of liquid Li coverage uniformity, no macroscopic surface erosion by plasma materials interaction, effective removal of 55% of the discharge heat flux using high pressure He cooling during ohmic discharges, and the demonstrated ability to restart Li flow for a second experiment performed a week after the first. With increasing Li flow rate, fuel particle recycling and Fe impurity radiation gradually decreased, and plasma performance slightly improved, but there was no impact on the edge tungsten influx. No obvious Li bursts appeared during operation with up to about 4.5 MW auxiliary heating power with peak heat flux reaching ~4 MW m –2 on FLiLi. In addition, a gradual mitigation of edge localized mode (ELM) activity was observed with FLiLi operation. Lastly, short-lived ELM-free phases were observed for the first time in EAST during FLiLi insertion, with increasing τ E and transient H 98(y, 2) < 2.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗