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MIRO Computational Model

A computational model calculates the excitation of water rotational levels and emission-line spectra in a cometary coma with applications for the Micro-wave Instrument for Rosetta Orbiter (MIRO). MIRO is a millimeter-submillimeter spectrometer that will be used to study the nature of cometary nuclei, the physical processes of outgassing, and the formation of the head region of a comet (coma). The computational model is a means to interpret the data measured by MIRO. The model is based on the accelerated Monte Carlo method, which performs a random angular, spatial, and frequency sampling of the radiation field to calculate the local average intensity of the field. With the model, the water rotational level populations in the cometary coma and the line profiles for the emission from the water molecules as a function of cometary parameters (such as outgassing rate, gas temperature, and gas and electron density) and observation parameters (such as distance to the comet and beam width) are calculated.

Broderick, Daniel↗

Correlation of Space Shuttle Landing Performance with Post-Flight Cardiovascular Dysfunction

Introduction: Microgravity induces cardiovascular adaptations resulting in orthostatic intolerance on re-exposure to normal gravity. Orthostasis could interfere with performance of complex tasks during the re-entry phase of Shuttle landings. This study correlated measures of Shuttle landing performance with post-flight indicators of orthostatic intolerance. Methods: Relevant Shuttle landing performance parameters routinely recorded at touchdown by NASA included downrange and crossrange distances, airspeed, and vertical speed. Measures of cardiovascular changes were calculated from operational stand tests performed in the immediate post-flight period on mission commanders from STS-41 to STS-66. Stand test data analyzed included maximum standing heart rate, mean increase in maximum heart rate, minimum standing systolic blood pressure, and mean decrease in standing systolic blood pressure. Pearson correlation coefficients were calculated with the null hypothesis that there was no statistically significant linear correlation between stand test results and Shuttle landing performance. A correlation coefficient? 0.5 with a p<0.05 was considered significant. Results: There were no significant linear correlations between landing performance and measures of post-flight cardiovascular dysfunction. Discussion: There was no evidence that post-flight cardiovascular stand test data correlated with Shuttle landing performance. This implies that variations in landing performance were not due to space flight-induced orthostatic intolerance.

McCluskey, R.↗

Cloud Detection over Snow and Ice with Oxygen A- and B-band Observations from the Earth Polychromatic Imaging Camera (EPIC)

Satellite cloud detection over snow and ice has been difficult for passive remote sensing instruments due to the lack of contrast between clouds and cold/bright surfaces; cloud mask algorithms often heavily rely on shortwave infrared (IR) channels over such surfaces. The Earth Polychromatic Imaging Camera (EPIC) on board the Deep Space Climate Observatory (DSCOVR) does not have infrared channels, which makes cloud detection over snow and ice surfaces even more challenging. This study investigates the methodology of applying EPIC's two oxygen absorption band pair ratios in the A band (764, 780 nm) and B band (688, 680 nm) for cloud detection over the snow and ice surfaces. We develop a novel elevation and zenith-angle-dependent threshold scheme based on radiative transfer model simulations that achieves significant improvements over the existing algorithm. When compared against a composite cloud mask based on geosynchronous Earth orbit (GEO) and low Earth orbit (LEO) sensors, the positive detection rate over snow and ice surfaces increased from around 36 % to 65 % while the false detection rate dropped from 50 % to 10 % for observations of January 2016 and 2017. The improvement in July is less substantial due to relatively better performance in the current algorithm. The new algorithm is applicable for all snow and ice surfaces including Antarctic, sea ice, high-latitude snow, and high-altitude glacier regions. This method is less reliable when clouds are optically thin or below 3 km because the sensitivity is low in oxygen band ratios for these cases.

EPIC↗

Somatic Mutation in Space/NASA Ames

We study the rate of somatic mutation accumulation in space, compared to Earth, with a view toward developing a new tool for cancer risk assessment. We believe that somatic mutation analysis may serve as a new tool for cancer risk assessment that may complement other cancer risk prediction methods currently in use. We propose to use high-performance computing power of the NASA Ames Supercomputer (NAS) to advance clinically relevant data mining in collaboration with the UCSF Cancer Moonshot Initiative. Somatic mutation analysis may have an important role to play in longitudinal studies of cancer development in selected populations and in astronauts.

somatic mutation↗

2.2.2.405 - Verdant/NREL Research Measurement Campaign

The marine renewable energy industry primarily uses thermoset composite materials for blades and other hydrodynamic components, which can have up to 50% reduction in strength when exposed to seawater and are not recyclable. Thermoplastic composite materials have been shown at a coupon-scale to have improved seawater saturated properties but have not been validated at full scale. The primary goal of the project is to demonstrate the structural properties of thermoplastic-fiberglass composite blades compared to epoxy-fiberglass composite blades in seawater at a tidal energy site on an operational turbine. Through this work, NREL manufactured, tested and deployed thermoplastic blades and a data acquisition system on Verdant Power's turbine TriFrame in the East River, NYC. The thermoplastic blades and DAQ were retrieved after a 6-month deployment with no signs of degradation and all cable connections, structural supports and strain gages had a 100% survival rate. The blades are currently undergoing post-deployment structural validation to compare their performance to traditional epoxy blades that were deployed for the same amount of time. This will increase confidence in thermoplastic materials and move it closer to commercial adoption, as well as increase confidence in the design of a DAQ and instrumentation method for a tidal turbine. However, due to an error in the DAQ software that was introduced after the DAQ and software were validated, there was no loads data collected during the deployment.

blade testing↗

Shielding and Activation Analyses for Beam Test Facility at SNS

The beam test facility (BTF) will be a copy of the accelerator front end of the Spallation Neutron Source (SNS) facility and will be used for test and development of new front-end equipment, for conducting research in accelerator physics (in a further build-out) for the SNS second target station moderator development (tests). The BTF is assembled and will be operating in the radio frequency (RF) on-site annex building. Negatively charged hydrogen ions (H{sup -}), generated at the ion source, will be accelerated to 2.5 MeV. The facility is capable of producing one-ms-long pulses at 60 Hz repetition rate with up to 50 mA peak current. This beam will be safely terminated in the beam stop. In order to support the BTF project from a radiation protection point of view, neutronics simulations and activation analyses were performed to develop shielding around the beam stop, evaluate dose rates in case of an accident and to evaluate the radionuclide inventory at the facility end-of-life for decommissioning. The challenge of the analyses was to consider low energy charges particles reaction physics to fit the calculations into our routine transport and activation methods as practiced for the much higher energy spallation environment. (authors)

43 PARTICLE ACCELERATORS↗

Stirred-Reactor Coupon Analysis: An International Round Robin Study

The objective of this task was to determine the precision of the SRCA technique when used to determine the dilute condition corrosion rate. To this end, an interlaboratory round robin study was conducted per the instructions in ASTM Practice E691 to measure the precision with which the SRCA test method can be conducted. Twelve independent labs from eleven different institutions each evaluated four glass compositions in three different conditions. The ASTM procedures recommend at least 6 labs participate in a round robin testing the same 3 materials in the same conditions to determine precision. In this case, 12 labs each performed 12 independent tests. This was only possible thanks to the multi-glass testing capability of the SRCA test. A total of 108 duplicate pairs were used to calculate the repeatability of the tests, with the same glass tested in the same vessel, producing as identical conditions as possible for the replicates. These test results were quite tightly clustered, with a median difference from the average value of the pair of only 2.9%. Based on the calculations outlined in ASTM E177-20 and a measured standard deviation of 4.74%, the intralaboratory repeatability limit (r) was calculated to be within 13.3% of the expected value with 95% confidence level. The reproducibility limit (R) of the test was examined using all 277 data points from the round robin. Because of the differences in dissolution rates due to pH variability and intrinsically for the 12 conditions tested, the reproducibility limits for each condition and overall were calculated from the percent relative residual value for each test. The SRCA test is expected to be reproducible within 64% of the expected value with a 95% confidence level.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

The utility of ultrasound guidance in transjugular liver biopsy: our experience

Purpose: To demonstrate the utility of ultrasound (US) guidance in improving the safety and efficacy of transjugular liver biopsy (TJLB) by analyzing all the TJLBs performed by us in the last 4 years. Materials and methods: Forty-seven patients who underwent TJLB in the last 4 years in our two centers were retrospectively analyzed. US guidance was used for all but for one patient during the two crucial steps of the procedure—for internal jugular vein (IJV) access and during the parenchymal biopsy. Biopsies were obtained under real-time sonographic guidance from the right lobe after confirming an adequate room for needle throw without breaching the liver capsule or any major hilar structures. Post-procedure complications, tissue yield, and histopathological adequacy of samples were analyzed. Results: Overall technical success rate was 100%. No major complications were found where ultrasound-assisted TJLB (uTJLB) was performed. One patient who underwent non-US guided TJLB had an event of a capsular breach and intra-peritoneal hemorrhage requiring coil embolization. Samples were of adequate dimension. Histopathological positivity was 100%. The overall complication rate for uTJLB was 4.7% which was due to minor complications in two patients. Conclusions: Addition of US unit to the angiographic suite is effortless and Interventional Radiologists being already skilled in US can easily implement this simple yet valuable modification to conventional TJLB procedures. Our experience on uTJLB further emphasizes the role of US guidance in improving the procedural success rate, safety profile, and efficacy in the histopathological outcome of TJLB in all patients irrespective of age and disease burden.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

WE-DE-201-03: Combined Use of 192Ir, 60Co, and 169Yb Sources with the Novel Direction Modulated Brachytherapy Tandem Applicator for High Dose Rate Brachytherapy Planning of Cervical Cancer

Purpose: To evaluate the improvement in plan quality when various combinations of 192Ir, 60Co, and 169Yb sources are used in combination with a novel direction modulated brachytherapy (DMBT) tandem applicator for high dose rate brachytherapy of cervical cancer. Methods: The proposed DMBT tandem applicator is designed for image-guided adaptive brachytherapy (IGABT), especially MRI, of cervical cancer. It has 6 peripheral holes of 1.3-mm width, grooved along a 5.4-mm diameter nonmagnetic tungsten alloy rod of density 18.0 g/cc, capable of generating directional dose profiles - leading to enhanced dose sculpting capacity through inverse planning. Monte Carlo simulations of the three HDR sources individually inside the DMBT applicator were performed and imported into an in-house developed inverse optimization code. We then performed inverse planning with 14 cervical cancer patients enrolled in EMBRACE study. In all patients, 3D MRI-based planning was performed while utilizing 1) tandem-ring and needles attached-to-ring (7 patients) and 2) tandem-ring and needles both attached-to-ring and free-hand-loaded (7 patients), in accordance with the GEC-ESTRO recommendations. All plans were normalized to receive the same HRCTV D90 and DVH parameters were evaluated. Results: The DMBT tandem was used in all cases. Overall, the combined use of two sources (192Ir-60Co and 192Ir-169Yb, but not 60Co-169Yb) generally produced better quality plans than with the 192Ir source alone in terms of sparing OARs. For example, up to 3.5, 4.4, and 3.9% individual reductions in D2cc were observed for the bladder, rectum, and sigmoid, respectively, between 192Ir-60Co and 192Ir-only plans for patient cases in #1. While up to 5.5, 2.0, and 5.7% individual reductions were observed for patient cases in #2. Conclusion: We have demonstrated that, in addition to “directional modulation” of DMBT, use of multiple sources with sufficient differences in energy can be utilized to achieve additional improvement in plan quality for IGABT of cervical cancer.

60 APPLIED LIFE SCIENCES↗

Techno-Economic Evaluation of Electrified Vehicle Options in Drayage Fleets

The electrification of drayage fleets offers potential economic and operational benefits, but the financial viability of electrified vehicles remains sensitive to battery cost, energy price, and fleet usage patterns. While total cost of ownership (TCO) is a useful benchmark, fleet operators and investors are equally concerned with investment performance metrics such as payback period (PB) and Internal Rate of Return (IRR), which better reflect financial risks and investment return timelines. This study develops a unified techno-economic framework that jointly evaluates TCO, PB, and IRR to determine when electrified trucks become cost-effective alternatives to diesel trucks. Building on a previously developed cost modeling tool and using real-world telematics data from a Class 8 drayage fleet at the Port of Savannah, the analysis incorporates projected battery cost trajectories, electricity and diesel price trends, vehicle efficiency improvements, and multiple battery capacities. Parameter ranges reflect widely cited projections and observed drayage-duty-cycle variability. A surrogate-modeling method approximates economic performance across thousands of battery cost–electricity price combinations, enabling high-resolution identification of conditions that achieve TCO parity, acceptable PB thresholds, and target IRR levels. Additionally, the study estimates the evolving share of the fleet that can feasibly electrify over time under multiple economic metrics. This integrated framework offers a novel, data-driven approach to inform risk-aware decision-making for fleet electrification and supports investment planning under evolving cost and operational conditions.

Sun, Ruixiao [ORNL] (ORCID:0000000341768676)↗

Developing the S 32 ( p , d ) S * 31 ( p ) ( γ ) reaction to probe the P 30 ( p , γ ) S 31 reaction rate in classical novae

Background: The 30 P(p,γ) 31 S reaction rate is one of the largest remaining sources of uncertainty in the final abundances of nuclei created in a classical nova involving a ONe white dwarf. The reaction rate directly influences silicon isotopic ratios, which are used as identifiers of presolar grains with nova origins. Additionally, the uncertainty in the 30 P(p,γ) 31 S reaction rate has been found to limit the use of nova nuclear thermometers based on observations of elemental ratios in nova ejecta. Purpose: Reduce uncertainties in the nuclear data for proton-unbound states in 31 S, which act as resonances for the 30 P(p,γ) 31 S reaction at classical nova temperatures, and develop a technique for high efficiency, high-resolution reaction-decay coincidence measurements. Methods: Here, the 32 S(p,d) 31 S reaction was used to populate the states of interest in 31 S. The experiment was performed at the Texas A&M Cyclotron Institute using the LLNL Hyperion array for the detection of charged particles and γ rays. A downstream silicon telescope was used to select reaction deuterons, and a single upstream silicon detector was used to measure protons emitted in the decay of unbound 31 S levels. Results: Several states in 31 S above the proton separation energy were observed to have been populated. Decay protons from the resonant states in 31 S were identified as events in the upstream silicon detectors that came in coincidence with deuterons in the downstream telescope. Protons emitted from these states were measured and branching ratios extracted. Conclusions: While no new reaction rate is derived, spin-parity assignments for several higher-lying proton unbound states have been confirmed. Measured p 0 branching ratios for these levels have been compared to previous measurements with good agreement, and in some cases provided a reduction in uncertainty. The previously identified T = 3/2 state may have been incorrectly assigned a large p 0 branching ratio in a previous measurement. The technique of measuring reaction-decay coincidences with a particle-gamma setup appears promising.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Machine learning-based optimization of air-cooled heat sinks

Machine learning-based models using Artificial Neural Network (ANN) and greedy search algorithm are used to optimize air-cooled parallel plate-finned heat sinks (PPFHSs) subjected to laminar flow over an extensive range of design parameters. Here, the thermal and hydraulic performances of PPFHSs are represented by heat transfer coefficient (h) and pressure drop (ΔP), respectively. Optimization objectives for PPFHS designs can vary from industry to industry depending on their design priorities. The present study proposes a novel and generalized optimization method that defines practical optimization objectives and provides an accurate optimization process to design effective PPFHSs for a wide range of industrial applications with different design requirements. Three optimization objectives are presented in this study: (i) the largest h PΔ, (ii) the largest h within a specified maximum allowed flow rate, and (iii) the lowest weight that maximizes h for operation within the maximum allowed flow rate. While the shortcoming of the first objective is demonstrated, the other two objectives are found to be suitable for designing effective heat sinks (HSs) across different applications. Results suggest a promising trend from the third objective to develop HSs with ~ 37-68% lower weight, 80-85% reduced ΔP, and negligible penalty in h compared with optimized HSs obtained from the second objective. However, since the third objective leads to HSs with thinner fins, structural analysis should be performed to ensure reliable operation of the HSs.

42 ENGINEERING↗

Real Time Data Analysis With the ATLAS Trigger at the LHC in Run-2

The trigger selection capabilities of the ATLAS detector have been significantly enhanced for the LHC Run- 2 in order to cope with the higher event rates and with the large number of simultaneous interactions (pile-up) per protonproton bunch crossing. A new hardware system, designed to analyse real time event-topologies at Level-1 came to full use in 2017. A hardware-based track reconstruction system, expected to be used real-time in 2018, is designed to provide track information to the high-level software trigger at its full input rate. The high-level trigger selections are largely relying on offline-like reconstruction techniques, and in some cases multivariate analysis methods. Despite the sudden change in LHC operations during the second half of 2017, which caused an increase in pile-up and therefore also in CPU usage of the trigger algorithms, the set of triggers (so called trigger menu) running online has undergone only minor modifications thanks to the robustness and redundancy of the trigger system, and the use of a levelling luminosity scheme in agreement with LHC and other experiments. Here, this presentation gives a brief yet comprehensive review of the real-time performance of the ATLAS trigger system in 2017. Considerations will be presented on the most relevant parameters of the trigger (efficiency to collect signal and output data rate) as well as details on some aspects of the algorithms which are run real-time on the High Level Trigger CPU farm.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Impact of installation faults in air conditioners and heat pumps in single-family homes on U.S. energy usage

To ensure that new residential air conditioners and heat pumps operate optimally, care must be taken during the initial system design and installation to avoid missteps that immediately degrade a system’s performance. Laboratory and simulation studies have quantified the impact that faults can have on capacity and efficiency. Field studies have demonstrated that installation-related faults are commonplace. However, the national impact of installation-related faults cannot be accurately estimated by only simulating a limited number of homes at several fault levels because of the variety of home characteristics and climates involved. In our analysis, we use an improved residential building stock simulation tool to predict the annual energy increase and additional utility costs resulting from two common installation faults: indoor airflow rate and refrigerant charge level. Our method considers the wide range of building characteristics and climate zones of the U.S. housing stock. We use existing field data to develop fault intensity probability distributions to inform our analysis. The study shows that these two faults result in approximately 20.7 TWh/y of additional energy use for central air conditioners and air-source heat pumps in U.S. single-family detached homes, which is a 9% increase over baseline (no-fault) usage, costing homeowners approximately $2.5 billion annually on utility bills. Air-source heat pumps are responsible for a disproportionate fraction of this energy use increase because of the larger number of operating hours compared to central air conditioners and the sensitivity of heating mode performance to the faults analyzed compared to cooling mode.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Investigation of ion-beam machining methods for replicated x-ray optics

The final figuring step in the fabrication of an optical component involves imparting a specified contour onto the surface. This can be expensive and time consuming step. The recent development of ion beam figuring provides a method for performing the figuring process with advantages over standard mechanical methods. Ion figuring has proven effective in figuring large optical components. The process of ion beam figuring removes material by transferring kinetic energy from impinging neutral particles. The process utilizes a Kaufman type ion source, where a plasma is generated in a discharge chamber by controlled electric potentials. Charged grids extract and accelerate ions from the chamber. The accelerated ions form a directional beam. A neutralizer outside the accelerator grids supplies electrons to the positive ion beam. It is necessary to neutralize the beam to prevent charging workpieces and to avoid bending the beam with extraneous electro-magnetic fields. When the directed beam strikes the workpiece, material sputters in a predicable manner. The amount and distribution of material sputtered is a function of the energy of the beam, material of the component, distance from the workpiece, and angle of incidence of the beam. The figuring method described here assumes a constant beam removal, so that the process can be represented by a convolution operation. A fixed beam energy maintains a constant sputtering rate. This temporally and spatially stable beam is held perpendicular to the workpiece at a fixed distance. For non-constant removal, corrections would be required to model the process as a convolution operation. Specific figures (contours) are achieved by rastering the beam over the workpiece at varying velocities. A unique deconvolution is performed, using series-derivative solution developed for the system, to determine these velocities.

Drueding, Thomas W.↗

Early therapeutic effects of adaptive servo-ventilation on cardiac sympathetic nervous function in patients with heart failure evaluated using a combination of {sup 11}C-HED PET and {sup 123}I-MIBG SPECT

Rationale: Adaptive servo-ventilation (ASV), a novel respiratory support therapy for sleep disorders, may improve cardiac function in heart failure (HF). However, the reasons that ASV improves cardiac function have not been fully studied especially in sympathetic nervous function (SNF). The purpose of the present study was to investigate the effects of ASV therapy on cardiac SNF in patients with HF. Methods: We evaluated ASV therapeutic effects before and 6 months after ASV therapy in 9 HF patients [57.3 ± 17.3 years old, left ventricular ejection fraction (LVEF) 36.1 ± 16.7%]. We performed echocardiography, polysomnography, biomarkers, {sup 11}C-hydroxyephedrine (HED) PET as a presynaptic function marker and planar {sup 123}I-metaiodobenzylguanidine (MIBG) to evaluate washout rate. Results: ASV therapy reduced apnea-hypopnea index (AHI) and improved plasma brain natriuretic peptide (BNP) concentration. In {sup 123}I-MIBG imaging, the early heart/mediastinum (H/M) ratio increased after ASV therapy (2.19 ± 0.58 to 2.40 ± 0.67; P = 0.045). Washout rate did not change (23.8 ± 7.3% to 23.8 ± 8.8%; P = 0.122). Global {sup 11}C-HED retention index (RI) improved from 0.068 ± 0.033/s to 0.075 ± 0.034/s (P = 0.029). Conclusions: ASV reduced AHI and improved BNP. ASV might initially improve presynaptic cardiac sympathetic nervous function in HF patients after 6 months of treatment.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Efficient data-driven models for prediction and optimization of geothermal power plant operations

Increasing the capacity of geothermal energy as a renewable resource calls for development and deployment of efficient control and optimization technologies for geothermal power plants. A data-driven prediction and optimization model is presented as a cost-effective and efficient alternative to physics-based approach. The model predicts power output and operational cost by propagating the influence of control and disturbance variables within an artificial neural network (ANN). Numerical experiments with simulated and field data from a real geothermal power plant are first used to demonstrate the prediction performance of the ANN model. The model is then adopted to maximize the net predicted power production by automatically adjusting the working fluid circulation rate. The optimization performance of the model in evaluated using a thermodynamic flowsheet simulation model. The workflow is applied to model and control the effect of ambient temperature on an air-cooled binary cycle power plant, which is complex and costly to perform using a physics-based predictive model. As a result, the performance of the method is demonstrated by applying it to both simulated and field datasets from a binary cycle geothermal power plant.

15 GEOTHERMAL ENERGY↗

First application of a liquid argon time projection chamber for the search for intranuclear neutron-antineutron transitions and annihilation in 40 Ar using the MicroBooNE detector

We present a novel methodology to search for intranuclear neutron-antineutron transition (n→n̅) followed by n̅-nucleon annihilation within an 40 Ar nucleus, using the MicroBooNE liquid argon time projection chamber (LArTPC) detector. A discovery of n→n̅ transition or a new best limit on the lifetime of this process would either constitute physics beyond the Standard Model or greatly constrain theories of baryogenesis, respectively. The approach presented in this paper makes use of deep learning methods to select n→n̅ events based on their unique features and differentiate them from cosmogenic backgrounds. The achieved signal and background efficiencies are (70.22 ± 6.04)% and (0.0020 ± 0.0003)%, respectively. A demonstration of a search is performed with a data set corresponding to an exposure of 3.32 ×10 26 neutron-years, and where the background rate is constrained through direct measurement, assuming the presence of a negligible signal. With this approach, no excess of events over the background prediction is observed, setting a demonstrative lower bound on the n→n̅ lifetime in 40 Ar of τ m ≳ 1.1×10 26 years, and on the free n→n̅ transition time of τ n→n̅ ≳ 2.6×10 5 s, each at the 90% confidence level. This analysis represents a first-ever proof-of-principle demonstration of the ability to search for this rare process in LArTPCs with high efficiency and low background.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗