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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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DOE OSTI2025

Cybersecurity and Infrastructure Security Agency (CISA) Infrastructure Security Division (ISD) Assessment Prioritization Project

The Cybersecurity and Infrastructure Security Agency’s Infrastructure Security Division (CISA ISD) manages a diverse portfolio of assessments across the nation’s critical infrastructure sectors. These assessments—ranging in type, scope, and complexity—are essential for identifying vulnerabilities and strengthening national security. However, the wide variation in assessment offerings and the increasing demand for limited resources have highlighted the need for a transparent, structured approach to prioritizing assessment activities. To address this challenge, CISA ISD partnered with Lawrence Livermore National Laboratory (LLNL) to review current assessment methodologies, analyze existing prioritization practices, and develop a comprehensive, national-security-focused prioritization framework. This report summarizes the project’s approach, key findings, and actionable recommendations for enhancing ISD’s assessment program.

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEF↗

DOE OSTI2026

Shaping the FutureWorkforce: Challenges and Lessons Learned in HPC Education from National Labs and Computing Centers

Workforce training at national laboratories and computing centers is essential and typically falls into two categories: foundational training for newcomers and advanced training for experienced users. Foundational topics—such as version control, build systems, and basic HPC usage—are largely transferable across institutions, while cluster-specific training varies due to differences in hardware, job schedulers, and local workflows. Training on emerging technologies is split between hardware-specific content and broadly applicable programming paradigms. Here, to reduce redundancy and increase impact, national labs, computing centers, and vendors are collaborating through initiatives like the HPC Training Working Group to share best practices, co-develop materials, and broaden outreach. These coordinated efforts aim to make HPC training more accessible, scalable, and consistent across the community.

HPC↗

DOE OSTI2024

Leveraging Artificial Intelligence to Expedite Antibody Design and Enhance Antibody–Antigen Interactions

This perspective sheds light on the transformative impact of recent computational advancements in the field of protein therapeutics, with a particular focus on the design and development of antibodies. Cutting-edge computational methods have revolutionized our understanding of protein–protein interactions (PPIs), enhancing the efficacy of protein therapeutics in preclinical and clinical settings. Central to these advancements is the application of machine learning and deep learning, which offers unprecedented insights into the intricate mechanisms of PPIs and facilitates precise control over protein functions. Despite these advancements, the complex structural nuances of antibodies pose ongoing challenges in their design and optimization. Our review provides a comprehensive exploration of the latest deep learning approaches, including language models and diffusion techniques, and their role in surmounting these challenges. We also present a critical analysis of these methods, offering insights to drive further progress in this rapidly evolving field. The paper includes practical recommendations for the application of these computational techniques, supplemented with independent benchmark studies. These studies focus on key performance metrics such as accuracy and the ease of program execution, providing a valuable resource for researchers engaged in antibody design and development. Through this detailed perspective, we aim to contribute to the advancement of antibody design, equipping researchers with the tools and knowledge to navigate the complexities of this field.

59 BASIC BIOLOGICAL SCIENCES↗

DOE OSTI2025

BOPTEST as a Platform for Building Controls and Grid-Interactive Buildings Workforce Training

Building automation and controls are becoming increasingly complex with the emergence of Grid Integrated Efficient Buildings (GEBs) as well as new highly efficient sequences of operation and data-driven control schemes. However, there remains a significant gap in hands-on training opportunities for building operators and technicians to gain practical experience with advanced control systems in a low-risk environment. This paper presents BOPTEST (Building Optimization Performance Test) as a suitable platform for workforce training in building controls and GEB technologies. BOPTEST provides a suite of standardized building simulation test cases with a REST API, real-time control interfaces through BACnet, semantic models connecting users to building data, and built-in calculation of control metrics and performance indicators. The platform enables trainees to interact with virtual buildings using industry-standard protocols while learning how to implement and innovate control strategies. The training platform is designed to offer a structured and interactive learning experience for building engineers, helping them effectively develop, learn, and retain skills in fault identification, troubleshooting, and correction. The workflow is divided into three main phases: 1) Setup, 2) Exercise, and 3) Review, each comprising specific activities performed by either the instructor or the student. Initial pilot training sessions have yielded positive feedback from instructors and participants and demonstrates that BOPTEST effectively fills an industry need for a low-risk training resource via simulation of real building control systems, allowing trainees to gain practical experience before working in the field. The platform's ability to provide immediate performance feedback while maintaining familiar industry interfaces makes it particularly suitable for workforce development programs. This work provides a replicable model for leveraging building simulation in control education and training.

Paul, Lazlo↗

NASA NTRS1972

Design criteria monograph for high-load high-speed rolling-contact bearings

Monograph was published which summarizes and systematically orders large body of successful techniques and practices developed for design of liquid rocket engine turbopump bearings. Document was written to organize and present significant experience and knowledge accumulated by NASA in development and operational programs.

Source record↗

NASA NTRS1975

A study of application of remote sensing to river forecasting. Volume 1: Executive summary

A project is described whose goal was to define, implement and evaluate a pilot demonstration test to show the practicability of applying remotely sensed data to operational river forecasting in gaged or previously ungaged watersheds. A secondary objective was to provide NASA with documentation describing the computer programs that comprise the streamflow forecasting simulation model used. A computer-based simulation model was adapted to a streamflow forecasting application and implemented in an IBM System/360 Model 44 computer, operating in a dedicated mode, with operator interactive control through a Model 2250 keyboard/graphic CRT terminal. The test site whose hydrologic behavior was simulated is a small basin (365 square kilometers) designated Town Creek near Geraldine, Alabama.

Source record↗

NASA NTRS1975

Identification and promulgation of objectives for OAST R and T programs, Task 2

Overall perspectives and guidelines are discussed for defining and promulgating NASA's Office of Aeronautics and Space Technology (OAST) objectives to meet national needs and goals in aeronautical, space, and nuclear technology. Emphasis is placed on the practicality of ultimately instituting objective-setting processes within the normal OAST operation, and of establishing quantitative measures to be used as a working management tool in determining the degree to which the objectives have been or are being met.

Source record↗

NASA NTRS1983

Practical guidance for the design of controls and displays for single pilot IFR

This paper represents a first step in developing the criteria for pilot interaction with advanced controls and displays in a single pilot IFR (SPIFR) environment. The research program presented is comprised of an analytical phase and an experimental phase. The analytical phase consisted of a review of fundamental considerations for pilot workload taking into account existing data, and using that data to develop a SPIFR pilot workload model. The rationale behind developing such a model was based on the concept that it is necessary to identify and quantify the most important components of pilot workload to guide the experimental phase of the research which consisted of an abbreviated flight test program. The purpose of the flight tests was to evaluate the workload associated with certain combinations of controls and displays in a flight environment. This was accommplished as a first step in building a data base for single pilot IFR controls and displays.

Hoh, R. H.↗

NASA NTRS1985

Remarks on rotor stability (A contribution to discussion during symposium on instability in rotating machinery)

Influence of nonlinear factors in fluid lubricated bearings on rotor vibrations is discussed as are computation of threshold of stability for systems with multiple degrees of freedom. The reason for this investigation was to learn more about the influence of tilting pad bearings on vertical rotors. The eigenvalues, the stability threshold, the response on the Heaviside-function and the unbalance response were calculated for a rigid rotor, a Jeffcott rotor and for the finite element model of a real rotor. The comparison of the linear and nonlinear calculations shows the limit of the linear calculations. The computation is supposed to show, that the model of the Jeffcott rotor is not sufficient in most practical cases to determine the stability threshold. This was known for some years, when computed results were compared with the behavior of real machines. That's why a program was developed, which is roughly described.

Kraemer, E.↗

NASA NTRS1991

On the theory of the synthesis of offset dual-shaped reflectors - Case examples

In an earlier paper by Galindo-Israel et al. (1987), the geometrical optics (GO) principles, constraints, and requirements of the dual- and single-offset-shaped reflector synthesis problem were collected and developed into a set of nonlinear first-order PDEs. An extension of the methods by which solutions to the PDEs can be obtained is presented, together with several case examples. These examples are independently analyzed by GO and physical optics diffraction methods. The starting point for the integration over each reflector can be taken on the outer rim, at the center, or at an intermediate point-the intermediate starting point being the more general case. The utility of the speed of this synthesis method is demonstrated. For example, the program utilized completes a synthesis in less than 45 s on a 386/20 personal computer and within a fraction of a second on a mainframe Cray. This makes practical the incorporation of the synthesis into a search algorithm that can optimize one or more parameters of the reflector system. As an example, the optimization of the mapping equations for low cross polarization is discussed.

Galindo-Israel, Victor↗

NASA NTRS1991

Computer modeling of a hot filament diamond deposition reactor

A commercial fluid mechanics program, FLUENT, has been applied to the modeling of a hot-filament diamond deposition reactor. Streamlines and contours of constant temperature and species concentrations are obtained for practical reactor geometries and conditions. The modeling is presently restricted to two-dimensional simulations and to a chemical mechanism of ten independent homogeneous and surface reactions. Comparisons are made between predicted power consumption, substrate temperature, and concentrations of atomic hydrogen and methyl-radical with values taken from the literature. The results to date indicate that the modeling can aid in the rational design and analysis of practical reactor configurations.

Kuczmarski, Maria A.↗

NASA NTRS1988

Probabilistic system identification in the time domain

The objective of system identification is to determine reliable dynamical models of a structure by systematically using its measured excitation and response. It brings together in an integrated fashion, experimental, analytical, and computational techniques in structural dynamics. Areas of application for system identification include the following: (1) Model Evaluation--assessing assumptions (linearity and equivalent viscous damping) and techniques (finite-element modeling) used to construct theoretical models of a structure; (2) Model Improvement--updating of a theoretical model to enable more accurate response predictions for possible future loads on the structure, or for control of the structure; (3) Empirical Modelling--developing empirical relationships (nonlinear models) or empirical parameter values (modal damping) because the present state of the art does not provide theoretical results; and (4) Damage Detection and Assessment--continual or episodic updating of a structural model through vibration monitoring to detect and locate any structural damage. It can be argued that since the construction or modification of models using test data is subject to inherent uncertainties, the above problems should be properly treated within a Bayesian probabilistic framework. Such a methodology is presented which allows the precision of the estimates of the model parameters to be computed. It also leads to a guiding principle in applications. Namely, when selecting a single model from a given class of models, one should take the most probable model in the class based on the experimental data. Practical applications of this principle are given which are based on the utilization of measured seismic motions in large civil structures. Examples include the application of a computer program MODE-ID to identify modal properties directly from seismic excitation and response time histories from a nine-story steel-frame building at JPL and from a freeway overpass bridge.

Beck, James L.↗

NASA NTRS1996

Thermohydrodynamic Analysis of Cryogenic Liquid Turbulent Flow Fluid Film Bearings

This report describes a thermohydrodynamic analysis and computer programs for the prediction of the static and dynamic force response of fluid film bearings for cryogenic applications. The research performed addressed effectively the most important theoretical and practical issues related to the operation and performance of cryogenic fluid film bearings. Five computer codes have been licensed by the Texas A&M University to NASA centers and contractors and a total of 14 technical papers have been published.

San Andres, Luis↗

NASA NTRS1999

Reliability/Risk Methods and Design Tools for Application in Space Programs

Since 1984 NASA has funded several major programs to develop Reliability/Risk Methods and tools for engineers to apply in the design and assessment of aerospace hardware. Two probabilistic software tools that show great promise for practical application are the finite element code NESSUS and the system risk analysis code QRAS. This paper examines NASA's past, present, and future directions in reliability and risk engineering applications, Both the NESSUS and QRAS software tools are detailed.

Townsend, John S.↗

NASA NTRS2003

Monitoring Outpatient Care

Each year, health care costs for managing chronically ill patients increase as the life expectancy of Americans continues to grow. To handle this situation, many hospitals, doctors practices, and home care providers are turning to disease management, a system of coordinated health care interventions and communications, to improve outpatient care. By participating in daily monitoring programs, patients with congestive heart failure, chronic obstructive pulmonary disease, diabetes, and other chronic conditions requiring significant self-care are facing fewer emergency situations and hospitalizations. Cybernet Medical, a division of Ann Arbor, Michigan-based Cybernet Systems Corporation, is using the latest communications technology to augment the ways health care professionals monitor and assess patients with chronic diseases, while at the same time simplifying the patients interaction with technology. Cybernet s newest commercial product for this purpose evolved from research funded by NASA, the National Institute of Mental Health, and the Advanced Research Projects Agency. The research focused on the physiological assessment of astronauts and soldiers, human performance evaluation, and human-computer interaction. Cybernet Medical's MedStar Disease Management Data Collection System is an affordable, widely deployable solution for improving in-home-patient chronic disease management. The system's battery-powered and portable interface device collects physiological data from off-the-shelf instruments.

Source record↗

NASA NTRS2003

Evolution of the Systems Engineering Education Development (SEED) Program at NASA Goddard Space Flight Center

The Systems Engineering Education Development (SEED) Program at NASA Goddard Space Flight Center develops systems engineers from existing discipline engineers. The program has evolved significantly since the report to INCOSE in 2003. This paper describes the SEED Program as it is now, outlines the changes over the last year, discusses current status and results, and shows the value of human systems and leadership skills for practicing systems engineers.

Bagg, Thomas C., III↗

NASA NTRS2004

Practical Pocket PC Application w/Biometric Security

I work in the Flight Software Engineering Branch, where we provide design and development of embedded real-time software applications for flight and supporting ground systems to support the NASA Aeronautics and Space Programs. In addition, this branch evaluates, develops and implements new technologies for embedded real-time systems, and maintains a laboratory for applications of embedded technology. The majority of microchips that are used in modern society have been programmed using embedded technology. These small chips can be found in microwaves, calculators, home security systems, cell phones and more. My assignment this summer entails working with an iPAQ HP 5500 Pocket PC. This top-of-the-line hand-held device is one of the first mobile PC's to introduce biometric security capabilities. Biometric security, in this case a fingerprint authentication system, is on the edge of technology as far as securing information. The benefits of fingerprint authentication are enormous. The most significant of them are that it is extremely difficult to reproduce someone else's fingerprint, and it is equally difficult to lose or forget your own fingerprint as opposed to a password or pin number. One of my goals for this summer is to integrate this technology with another Pocket PC application. The second task for the summer is to develop a simple application that provides an Astronaut EVA (Extravehicular Activity) Log Book capability. The Astronaut EVA Log Book is what an astronaut would use to report the status of field missions, crew physical health, successes, future plans, etc. My goal is to develop a user interface into which these data fields can be entered and stored. The applications that I am developing are created using eMbedded Visual C++ 4.0 with the Pocket PC 2003 Software Development Kit provided by Microsoft.

Logan, Julian↗

NASA NTRS2010

Final Report for the Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2030 to 2035 Period, N+3 Supersonic Program

The N+3 Final Report documents the work and progress made by Lockheed Martin Aeronautics in response to the NASA sponsored program "N+3 NRA Advanced Concept Studies for Supersonic Commercial Transports Entering Service in the 2030 to 2035 Period." The key technical objective of this effort was to generate promising supersonic concepts for the 2030 to 2035 timeframe and to develop plans for maturing the technologies required to make those concepts a reality. The N+3 program is aligned with NASA's Supersonic Project and is focused on providing alternative system-level solutions capable of overcoming the efficiency, environmental, and performance barriers to practical supersonic flight

Morgenstern, John↗