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Human otolith function, experiment M009

The experiments that were performed during the Gemini 5 and 7 missions resulted in quantitative information concerning otolithic function and orientation of four subjects exposed to an orbiting spacecraft environment for prolonged periods of time. Preflight counterrolling measurements revealed significant differences between crewmembers with regard to the basic magnitude of otolith response. However, after the flight, each crewmember maintained his respective preflight level of response. This was indicative that no significant change in otolithic sensitivity occurred as a result of the flight, or at least no change persisted long enough to be recorded several hours after recovery. The EVLH data recorded for each subject confirmed the observation that a coordinate space sense exists even in a weightless environment if contact cues are adequate. However, it was noted that the apparent location of the horizontal within the spacecraft may not agree necessarily with its physical correlate in the spacecraft.

Graybiel, A.↗

Human performance and physiological function during a 24-hr exposure to 1 percent bromotrifluoromethane (Halon 1301)

Performance and physiological measurements were obtained from four pairs of men exposed for 24 hr to 1 percent (10,000 ppm) Halon 1301 (CBrF3) and to air with order counterbalanced using a double-blind protocol. Cognitive and motor performance was assessed before, during, and after the exposures, using seven scales of the Automated Portable Testing System, which produced 13 measures of performance. Halon inhalation induced decrements in 2 of the 13 measures, but actual and estimated magnitudes of the decrements were no greater than 5 percent of baseline values. Physiological data obtained before, during, and after the exposures revealed significant changes during Halon inhalation for 6 of the 52 variables assessed; however, all physiological values remained within clinically acceptable limits. No cardiovascular effects were noted. This study demonstrated that exposure to 1 percent Halon 1301 for 24 hr can produce minor disturbance of central nervous system function as assessed by cognitive tasks.

Calkins, D. S.↗

Cognitive engineering models in space systems

NASA space systems, including mission operations on the ground and in space, are complex, dynamic, predominantly automated systems in which the human operator is a supervisory controller. Models of cognitive functions in complex systems are needed to describe human performance and form the theoretical basis of operator workstation design, including displays, controls, and decision aids. Currently, there several candidate modeling methodologies. They include the Rasmussen abstraction/aggregation hierarchy and decision ladder, the goal-means network, the problem behavior graph, and the operator function model. The research conducted under the sponsorship of this grant focuses on the extension of the theoretical structure of the operator function model and its application to NASA Johnson mission operations and space station applications. The initial portion of this research consists of two parts. The first is a series of technical exchanges between NASA Johnson and Georgia Tech researchers. The purpose is to identify candidate applications for the current operator function model; prospects include mission operations and the Data Management System Testbed. The second portion will address extensions of the operator function model to tailor it to the specific needs of Johnson applications. At this point, we have accomplished two things. During a series of conversations with JSC researchers, we have defined the technical goal of the research supported by this grant to be the structural definition of the operator function model and its computer implementation, OFMspert. Both the OFM and OFMspert have matured to the point that they require infrastructure to facilitate use by researchers not involved in the evolution of the tools. The second accomplishment this year was the identification of the Payload Deployment and Retrieval System (PDRS) as a candidate system for the case study. In conjunction with government and contractor personnel in the Human-Computer Interaction Lab, the PDRS was identified as the most accessible system for the demonstration. Pursuant to this a PDRS simulation was obtained from the HCIL and an initial knowledge engineering effort was conducted to understand the operator's tasks in the PDRS application. The preliminary results of the knowledge engineering effort and an initial formulation of an operator function model (OFM) are contained in the appendices.

Mitchell, Christine M.↗

Low-Dose Hyper-Radiosensitivity Is Not a Common Effect in Normal Asynchronous and G2-Phase Fibroblasts of Cancer Patients

Purpose: In our previous study, using the micronucleus assay, a low-dose hyper-radiosensitivity (HRS)-like phenomenon was observed for normal fibroblasts of 2 of the 40 cancer patients investigated. In this article we report, for the first time, the survival response of primary fibroblasts from 25 of these patients to low-dose irradiation and answer the question regarding the effect of G2-phase enrichment on HRS elicitation. Methods and Materials: The clonogenic survival of asynchronous as well as G2-phase enriched fibroblast populations was measured. Separation of G2-phase cells and precise cell counting was performed using a fluorescence-activated cell sorter. Sorted and plated cells were irradiated with single doses (0.1-4 Gy) of 6-MV x-rays. For each patient, at least 4 independent experiments were performed, and the induced-repair model was fitted over the whole data set to confirm the presence of HRS effect. Results: The HRS response was demonstrated for the asynchronous and G2-phase enriched cell populations of 4 patients. For the rest of patients, HRS was not defined in either of the 2 fibroblast populations. Thus, G2-phase enrichment had no effect on HRS elicitation. Conclusions: The fact that low-dose hyper-radiosensitivity is not a common effect in normal human fibroblasts implies that HRS may be of little consequence in late-responding connective tissues with regard to radiation fibrosis.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Clinical Natural Language Processing for Radiation Oncology: A Review and Practical Primer

Natural language processing (NLP), which aims to convert human language into expressions that can be analyzed by computers, is one of the most rapidly developing and widely used technologies in the field of artificial intelligence. Natural language processing algorithms convert unstructured free text data into structured data that can be extracted and analyzed at scale. In medicine, this unlocking of the rich, expressive data within clinical free text in electronic medical records will help untap the full potential of big data for research and clinical purposes. Recent major NLP algorithmic advances have significantly improved the performance of these algorithms, leading to a surge in academic and industry interest in developing tools to automate information extraction and phenotyping from clinical texts. Thus, these technologies are poised to transform medical research and alter clinical practices in the future. Radiation oncology stands to benefit from NLP algorithms if they are appropriately developed and deployed, as they may enable advances such as automated inclusion of radiation therapy details into cancer registries, discovery of novel insights about cancer care, and improved patient data curation and presentation at the point of care. However, challenges remain before the full value of NLP is realized, such as the plethora of jargon specific to radiation oncology, nonstandard nomenclature, a lack of publicly available labeled data for model development, and interoperability limitations between radiation oncology data silos. Successful development and implementation of high quality and high value NLP models for radiation oncology will require close collaboration between computer scientists and the radiation oncology community. Here, we present a primer on artificial intelligence algorithms in general and NLP algorithms in particular; provide guidance on how to assess the performance of such algorithms; review prior research on NLP algorithms for oncology; and describe future avenues for NLP in radiation oncology research and clinics.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

A data engineering approach for sustainable chemical end-of-life management

The presence of chemicals causing significant adverse human health and environmental effects during end-of-life (EoL) stages is a challenge for implementing sustainable management efforts and transitioning towards a safer circular life cycle. Conducting chemical risk evaluation and exposure assessment of potential EoL scenarios can help understand the chemical EoL management chain for its safer utilization in a circular life-cycle environment. However, the first step is to track the chemical flows, estimate releases, and potential exposure pathways. Hence, this work proposes an EoL data engineering approach to perform chemical flow analysis and screening to support risk evaluation and exposure assessment for designing a safer circular life cycle of chemicals. This work uses publicly-available data to identify potential post-recycling scenarios (e.g., industrial processing/use operations), estimate inter-industry chemical transfers, and exposure pathways to chemicals of interest. Furthermore, a case study demonstration shows how the data engineering framework identifies, estimates, and tracks chemical flow transfers from EoL stage facilities (e.g., recycling and recovery) to upstream chemical life cycle stage facilities (e.g., manufacturing). Also, the proposed framework considers current regulatory constraints on closing the recycling loop operations and provides a range of values for the flow allocated to post-recycling uses associated with occupational exposure and fugitive air releases from EoL operations.

54 ENVIRONMENTAL SCIENCES↗

Improved Throughput and Analysis of Scratch Test Results via Automation and Machine Learning

A data analysis automation interface that incorporates machine learning (ML) has been developed to improve productivity, efficiency, and consistency in identifying and defining critical load values (or other values associated with optically identifiable characteristics) of a coating when a scratch test is performed. In this specific program, the machine learning component of the program has been trained to identify the Critical Load 2 (L C2 ) value by analyzing images of the scratch tracks created in each test. An optical examination of the scratch by a human operator is currently used to determine where this value occurs. However, the vagueness of the standard has led to varying interpretations and nonuniform usage by different operators at different laboratories where the test is implemented, resulting in multiple definitions of the desired parameter. Using a standard set of training and validation images to create the dataset, the critical load can be identified consistently amongst different laboratories using the automation interface without requiring the training of human operators. When the model was used in conjunction with an instrument manufacturer's scratch test software, the model produced accurate and repeatable results and defined L C2 values in as little as half of the time compared to a human operator. When combined with a program that automates other aspects of the scratch testing process usually conducted by a human operator, scratch testing and analysis can occur with little to no intervention from a human beyond initial setup and frees them to complete other work in the lab.

36 MATERIALS SCIENCE↗

Talent Acquisition in Scientific and Engineering Disciplines: A Case Study of National Laboratory (TASED) [Thesis]

Identifying the hindrances to performing effective talent acquisition within the science, technology, engineering, and mathematics field is an important topic for technical hiring managers. Top candidates have multiple options during highly competitive market conditions requiring managers to look for unique solutions which diverge from competition. Prior to this study there has been very little research considering national laboratory research and development challenges from a technical hiring manager’s talent acquisition perspective. Utilizing a unique combination of national laboratory multi-organization survey, pilot study, Human Resource (HR) tracking data and trust based business strategy to enhance partnering this research finds hiring managers can leverage out of the box techniques to improve internal processes while developing industry support to target highly qualified individuals. This methodology could be utilized by technical hiring managers across federal national laboratory enterprise to effectively capture next generation staff and leadership talent who align with their organization professionally as well as social culture.

99 GENERAL AND MISCELLANEOUS↗

Downsizing Visualization Platforms: From Crays to Indigos and Beyond

Despite its increasingly negative connotation in other domains, "downsizing" is a positive trend as it applies to the computer hardware necessary to perform scientific visualization. In this talk, we will consider how the visualization of a particular data set, the Digital Terrain Model (DTM) derived from the Viking Orbiter imagery, has been realized in three distinct projects over the past decade. These examples serve to demonstrate how the vast improvements in computational performance both decrease the cost of such visualization efforts, and permit an increasing level of interactivity. We then consider how even today's graphical systems require the visualization designer to make intelligent choices and trade-offs in database rendering. Finally, we discuss how insights from an understanding of human visual perception can guide these design decisions, and suggest new options for visualization hardware and software.

Kaiser, Mary K.↗

Are You Talking to Me? Dialogue Systems Supporting Mixed Teams of Humans and Robots

This position paper describes an approach to building spoken dialogue systems for environments containing multiple human speakers and hearers, and multiple robotic speakers and hearers. We address the issue, for robotic hearers, of whether the speech they hear is intended for them, or more likely to be intended for some other hearer. We will describe data collected during a series of experiments involving teams of multiple human and robots (and other software participants), and some preliminary results for distinguishing robot-directed speech from human-directed speech. The domain of these experiments is Mars-analogue planetary exploration. These Mars-analogue field studies involve two subjects in simulated planetary space suits doing geological exploration with the help of 1-2 robots, supporting software agents, a habitat communicator and links to a remote science team. The two subjects are performing a task (geological exploration) which requires them to speak with each other while also speaking with their assistants. The technique used here is to use a probabilistic context-free grammar language model in the speech recognizer that is trained on prior robot-directed speech. Intuitively, the recognizer will give higher confidence to an utterance if it is similar to utterances that have been directed to the robot in the past.

Dowding, John↗

Context-dependent arm pointing adaptation

We sought to determine the effectiveness of head posture as a contextual cue to facilitate adaptive transitions in manual control during visuomotor distortions. Subjects performed arm pointing movements by drawing on a digitizing tablet, with targets and movement trajectories displayed in real time on a computer monitor. Adaptation was induced by presenting the trajectories in an altered gain format on the monitor. The subjects were shown visual displays of their movements that corresponded to either 0.5 or 1.5 scaling of the movements made. Subjects were assigned to three groups: the head orientation group tilted the head towards the right shoulder when drawing under a 0.5 gain of display and towards the left shoulder when drawing under a 1.5 gain of display; the target orientation group had the home and target positions rotated counterclockwise when drawing under the 0.5 gain and clockwise for the 1.5 gain; the arm posture group changed the elbow angle of the arm they were not drawing with from full flexion to full extension with 0.5 and 1.5 gain display changes. To determine if contextual cues were associated with display alternations, the gain changes were returned to the standard (1.0) display. Aftereffects were assessed to determine the efficacy of the head orientation contextual cue compared to the two control cues. The head orientation cue was effectively associated with the multiple gains. The target orientation cue also demonstrated some effectiveness while the arm posture cue did not. The results demonstrate that contextual cues can be used to switch between multiple adaptive states. These data provide support for the idea that static head orientation information is a crucial component to the arm adaptation process. These data further define the functional linkage between head posture and arm pointing movements.

Clinical Trial↗

Jiangsu Nanjing – Lawrence Berkeley Life Sciences Center for Translational Medicine (CRADA AWD00000392)

Project 1: Our previous work demonstrated that the CES biomarker can be an approximate measure for the levels of chromosomal instability (CIN) in cancer, and that the CES (for Centromere and kinetochore gene Expression Score) biomarker effectively predicts which cancer patients benefit from adjuvant chemotherapies in lung and other cancer types. Such a utility can potentially reduce overtreatment that is common in lung cancer treatment. We determined performance of the multiplex Quantigene RNA assay platform for measuring mRNA levels of CES genes using clinical tumor samples. These experiments determined sensitivity, specificity and detection limit of 12 CES genes and 5 control genes using clinical tumor samples with paired normal tissue samples. We determined how sample concentration and storage conditions affect measurement sensitivity and specificity, and whether sample storage over time affects result reproducibility. Importantly, we confirmed that early stage lung cancer CES values are significantly higher than those of paired normal tissues in all cases. This result greatly extended our bioinformatic data mining by confirming that we can measure CES values directly from patient tumor tissue, and that tumors have higher CES values than normal tissues. Unfortunately, our CRADA partner in China did not finish measuring CES expression levels for a larger group of ~100 tumor samples, due to the long period time required for human subject review in China. This delay prevented us from generating enough additional data to generate a significant statistical model. We finished analyzing all the data acquired during the CRADA, and are trying to work collaboratively with the Shanghai University Lung Cancer Hospital to complete the analysis of more tumor samples. Although no publications have resulted from this research, the findings are crucial for ongoing efforts to obtain funding to develop the technology to address problems in deciding on appropriate treatment regimens for individual patients, in clinical settings. Project 2: The overarching milestones of CRADA Project 2 were to investigate the role of FAM83 family members in cancer progression. Two publications resulted from this work which are highlighted below. The first major goal of the CRADA was to broadly assess the role of FAM83 family oncogenes in human cancer using a multi-omic bioinformatic approach (Snijders et al 2017 Mol. Oncol 11). The second major goal was to specifically assess the role of FAM83D in a cancer progression and metastasis (Yin et al 2019 Cell Oncol; in revision). Role of FAM83 family oncogenes in human cancers Recent studies from our laboratory as well as other groups have demonstrated that FAM83 family members have oncogenic properties and have significantly elevated expression levels in multiple human tumor types, including breast cancers (BC). We performed an integrative multi-omics bio-informatic analysis of the role of FAM83 family oncogenes in human cancers. Our findings were published in the journal Molecular Oncology (Snijders et al; Mol Oncol. 2017 Feb;11(2):167-179). Highlights from this manuscript are: • Transcriptional levels of FAM83 family members are frequently and dramatically elevated across tumor types in human • DNA copy number increase appears to be a potential mechanism for increased expression of FAM83 genes • FAM83 family gene signature is associated with poor survival across human tumor types • FAM83 gene alterations are significantly correlated with TP53, PIK3CA and Ecadherin mutations. In conclusion, this analysis of FAM83 family members opened up a new horizon for further understanding the significance of FAM83 genes in cancer and clinical applications in diagnosis, prognosis and therapy. Role of FAM83D in human non-small cell lung cancer (NSCLC) metastasis and its impact on chemotherapy. Lung cancer is one of the most common malignant tumors in the world and non-small cell lung cancer (NSCLC) accounts for 80~85% of all diagnosed lung cancer cases, one of the deadliest cancers worldwide. FAM83D has been proposed as an oncoprotein in several types of human cancer, yet its role and molecular mechanism in human non-small cell lung cancer (NSCLC) metastasis and its impact on chemotherapy are poorly understood. We evaluated the expression of FAM83D in NSCLC cells and cancerous tissues and its prognostic significance, then investigated the effect of FAM83D on tumorigenic phenotypes such as cell proliferation, EMT and invasive capability, and finally assessed impact of FAM83D on NSCLC chemo-drug resistance. The results of this study are currently in revision at the journal Cellular Oncology. Highlights from this manuscript are: • FAM83D expression is elevated in NSCLC cells and tissues and associated with poor prognosis • FAM83D promotes NSCLC cell proliferation • FAM83D induces EMT in NSCLC cells • FAM83D promotes NSCLC cell migration and invasion • FAM83D promotes EMT and invasive capability of NSCLC cells by regulating AKT/mTOR pathway • FAM83D silencing increases cisplatin sensitivity of NSCLC cells In summary, this second study demonstrated for the first time that FAM83D promoted EMT and metastasis of NSCLC cells through AKT/mTOR signal pathway as well as increased the sensitivity of NSCLC to cisplatin. This study may provide potential targets for advanced NSCLC treatment and personalized therapy.

59 BASIC BIOLOGICAL SCIENCES↗

Enhanced Oblique Decision Tree Enabled Policy Extraction for Deep Reinforcement Learning in Power System Emergency Control

Deep reinforcement learning (DRL) algorithms have successfully solved many challenging problems in various power system control scenarios. However, their decision-making process is usually regarded as black-boxes. Furthermore, how DRL models interact with human intelligence remains an open problem. Thus, this paper proposes a policy extraction framework to extract a complex DRL model into an explainable policy. This framework includes three parts: 1) DRL training and data generation. We train an agent for a specific control task and generate data, which contains the control policy of the agent. 2) Policy extraction. We propose an information gain rate based weighted oblique decision tree (IGR-WODT) for DRL policy extraction. 3) Policy evaluation. We define three metrics to evaluate the performance of the proposed approach. A case study for the under-voltage load shedding problem shows that the IGR-WODT presents a performance enhancement compared with DRL, weighted oblique decision tree, and univariate decision tree. The proposed policy extraction method could provide an intuitive explanation of the neural network decision-making process to the dispatchers when making final decisions on power grid operation. Also, the resulted rule-based controller could replace the deep neural network-based controller in many field edge devices with limited computing resources, providing comparable performance.

deep reinforcement learning↗

Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS)

The capabilities of current computer simulations provide a unique opportunity to model small-angle scattering (SAS) data at the atomistic level, and to include other structural constraints ranging from molecular and atomistic energetics to crystallography, electron microscopy and NMR. This extends the capabilities of solution scattering and provides deeper insights into the physics and chemistry of the systems studied. Realizing this potential, however, requires integrating the experimental data with a new generation of modelling software. To achieve this, the CCP-SAS collaboration (http://www.ccpsas.org/) is developing open-source, high-throughput and user-friendly software for the atomistic and coarse-grained molecular modelling of scattering data. Robust state-of-the-art molecular simulation engines and molecular dynamics and Monte Carlo force fields provide constraints to the solution structure inferred from the small-angle scattering data, which incorporates the known physical chemistry of the system. The implementation of this software suite involves a tiered approach in which GenApp provides the deployment infrastructure for running applications on both standard and high-performance computing hardware, and SASSIE provides a workflow framework into which modules can be plugged to prepare structures, carry out simulations, calculate theoretical scattering data and compare results with experimental data. GenApp produces the accessible web-based front end termed SASSIE-web , and GenApp and SASSIE also make community SAS codes available. Applications are illustrated by case studies: (i) inter-domain flexibility in two- to six-domain proteins as exemplified by HIV-1 Gag, MASP and ubiquitin; (ii) the hinge conformation in human IgG2 and IgA1 antibodies; (iii) the complex formed between a hexameric protein Hfq and mRNA; and (iv) synthetic `bottlebrush' polymers.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

C3F: Collaborative Container-based Model Coupling Framework

Solving complex real-world grand challenge problems requires in-depth collaboration of researchers from multiple disciplines. Such collaboration often involves harnessing multiscale and multi-dimensional data and combining models from different fields to simulate systems. However, the progress on this front has been limited mainly due to significant gaps in domain knowledge and tools that are typically employed in silos of the domains. Researchers from different fields face considerable barriers to understanding and reusing each other’s data/models in order to collaborate effectively. For example, in solving the global sustainability problems, researchers from hydrology, climate science, agriculture, and economics need to run their respective models to study different components of the global and local food, energy and water systems while, at the same time, need to interact with other researchers and integrate the results of one model with another. Developing this kind of model coupling workflow calls for (1) a large amount of data being processed and exchanged across domains and organizations, (2) identifying and processing the output of one model to make it ready for integration into another model, (3) controlling the workflow dynamically so that it runs until a certain convergence condition or other criteria is met, and (4) close collaboration among the modelers to explore, tune, and test the configuration and data transformation needed to link the models. We have developed C3F, a flexible collaborative model coupling framework to help researchers accelerate their model integration and linking efforts by leveraging advanced cyberinfrastructure such as high-performance computing and virtual containers. In this paper, we describe our experience and lessons learned in developing this cyberinfrastructure solution to support the linking of Water Balance Model (WBM) and SIMPLE-G agricultural economic model in an NSF funded INFEWS project and a DOE-funded Program on Coupled Human and Earth Systems (PCHES) to study the implications of groundwater scarcity for food-energy-water systems. The C3F model coupling framework can be extended to facilitate other model linkages as well.

containerization↗

Data-Enabled Fusion Technology (Final Scientific/Technical Report)

Advancing Scientific Understanding in Fusion Energy and Machine Learning This research represented a significant step forward in machine learning (ML) applications for fusion energy experiments. The project integrated advanced data-driven modeling, optimization techniques, and artificial intelligence to enhance the predictive capabilities and operational efficiency of plasma-based fusion systems. Specifically, tasks focused on ML-enhanced diagnostics, operator guidance tools, and predictive modeling helped improve the ability to interpret complex fusion experiments. Key areas of advancement included: 1) data-driven plasma control, i.e., using ML algorithms to optimize experimental conditions and classify plasma behaviors based on historical data; 2) spectroscopy and diagnostics, i.e., applying AI models to extract previously inaccessible insights from experimental spectroscopy data; and 3) configuration mapping and operator guidance, i.e., developing a predictive framework to assist scientists in identifying the most effective experimental parameters, reducing reliance on manual adjustments. By refining these ML-driven techniques, the project contributed to the broader scientific community’s understanding of plasma dynamics and fusion energy viability. Technical Effectiveness and Economic Feasibility The methods investigated demonstrated high technical effectiveness, as reflected in milestones assessing the predictive accuracy, performance, and optimization of fusion configurations. The development of an Operator Guidance Tool (OGT), for example, led to more precise control of plasma conditions by learning from experimental data and offering real-time adjustments. From an economic standpoint, DeFT provided: 1) the ability to reduce trial-and-error experimentation, which lowered operational costs; 2) improved data interpretation methods, which enabled more efficient resource allocation in large-scale fusion research projects; and 3) the automation of key diagnostic tasks, which reduced manual labor and human error, increasing overall efficiency. 13 The final assessments of predictive models and optimization strategies demonstrated that these approaches were scalable and could be implemented across multiple fusion energy research programs. Public Benefit and Societal Impact This project contributed directly to the broader goal of achieving sustainable and commercially viable fusion energy, which had profound implications for clean energy production and climate change mitigation. The integration of AI-driven solutions into fusion research: 1) sped up scientific discovery, accelerating progress towards achieving energy breakthroughs; 2) reduced the cost of experimentation, making fusion research more accessible; and 3) provided a framework for future AI applications in high-energy physics, benefiting adjacent fields like space exploration, material science, and renewable energy. Additionally, by fostering collaborations between AI researchers and plasma physicists, this project promoted interdisciplinary innovation that could lead to broader applications beyond fusion research.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

The Computerized Anatomical Man (CAM) model

A computerized anatomical man (CAM) model, representing the most detailed and anatomically correct geometrical model of the human body yet prepared, has been developed for use in analyzing radiation dose distribution in man. This model of a 50-percentile standing USAF man comprises some 1100 unique geometric surfaces and some 2450 solid regions. Internal body geometry such as organs, voids, bones, and bone marrow are explicitly modeled. A computer program called CAMERA has also been developed for performing analyses with the model. Such analyses include tracing rays through the CAM geometry, placing results on magnetic tape in various forms, collapsing areal density data from ray tracing information to areal density distributions, preparing cross section views, etc. Numerous computer drawn cross sections through the CAM model are presented.

Billings, M. P.↗