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All sourcesNASA NTRSDOE OSTI
DOE OSTI2015

TU-G-201-01: What Therapy Physicists Need to Know About CT and PET/CT: Terminology and Latest Developments

This session will update therapeutic physicists on technological advancements and radiation oncology features of commercial CT, MRI, and PET/CT imaging systems. Also described are physicists’ roles in every stage of equipment selection, purchasing, and operation, including defining specifications, evaluating vendors, making recommendations, and optimal and safe use of imaging equipment in radiation oncology environment. The first presentation defines important terminology of CT and PET/CT followed by a review of latest innovations, such as metal artifact reduction, statistical iterative reconstruction, radiation dose management, tissue classification by dual energy CT and spectral CT, improvement in spatial resolution and sensitivity in PET, and potentials of PET/MR. We will also discuss important technical specifications and items in CT and PET/CT purchasing quotes and their impacts. The second presentation will focus on key components in the request for proposal for a MRI simulator and how to evaluate vendor proposals. MRI safety issues in radiation Oncology, including MRI scanner Zones (4-zone design), will be discussed. Basic MR terminologies, important functionalities, and advanced features, which are relevant to radiation therapy, will be discussed. In the third presentation, justification of imaging systems for radiation oncology, considerations in room design and construction in a RO department, shared use with diagnostic radiology, staffing needs and training, clinical/research use cases and implementation, will be discussed. The emphasis will be on understanding and bridging the differences between diagnostic and radiation oncology installations, building consensus amongst stakeholders for purchase and use, and integrating imaging technologies into the radiation oncology environment. Learning Objectives: Learn the latest innovations of major imaging systems relevant to radiation therapy Be able to describe important technical specifications of CT, MRI, and PET/CT Understand the process of budget request, equipment justification, comparisons of technical specifications, site visits, vendor selection, and contract development.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2015

TU-G-201-02: An MRI Simulator From Proposal to Operation

This session will update therapeutic physicists on technological advancements and radiation oncology features of commercial CT, MRI, and PET/CT imaging systems. Also described are physicists’ roles in every stage of equipment selection, purchasing, and operation, including defining specifications, evaluating vendors, making recommendations, and optimal and safe use of imaging equipment in radiation oncology environment. The first presentation defines important terminology of CT and PET/CT followed by a review of latest innovations, such as metal artifact reduction, statistical iterative reconstruction, radiation dose management, tissue classification by dual energy CT and spectral CT, improvement in spatial resolution and sensitivity in PET, and potentials of PET/MR. We will also discuss important technical specifications and items in CT and PET/CT purchasing quotes and their impacts. The second presentation will focus on key components in the request for proposal for a MRI simulator and how to evaluate vendor proposals. MRI safety issues in radiation Oncology, including MRI scanner Zones (4-zone design), will be discussed. Basic MR terminologies, important functionalities, and advanced features, which are relevant to radiation therapy, will be discussed. In the third presentation, justification of imaging systems for radiation oncology, considerations in room design and construction in a RO department, shared use with diagnostic radiology, staffing needs and training, clinical/research use cases and implementation, will be discussed. The emphasis will be on understanding and bridging the differences between diagnostic and radiation oncology installations, building consensus amongst stakeholders for purchase and use, and integrating imaging technologies into the radiation oncology environment. Learning Objectives: Learn the latest innovations of major imaging systems relevant to radiation therapy Be able to describe important technical specifications of CT, MRI, and PET/CT Understand the process of budget request, equipment justification, comparisons of technical specifications, site visits, vendor selection, and contract development.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2015

TU-G-201-03: Imaging Systems in Radiotherapy: Buying, Installing, and Using

This session will update therapeutic physicists on technological advancements and radiation oncology features of commercial CT, MRI, and PET/CT imaging systems. Also described are physicists’ roles in every stage of equipment selection, purchasing, and operation, including defining specifications, evaluating vendors, making recommendations, and optimal and safe use of imaging equipment in radiation oncology environment. The first presentation defines important terminology of CT and PET/CT followed by a review of latest innovations, such as metal artifact reduction, statistical iterative reconstruction, radiation dose management, tissue classification by dual energy CT and spectral CT, improvement in spatial resolution and sensitivity in PET, and potentials of PET/MR. We will also discuss important technical specifications and items in CT and PET/CT purchasing quotes and their impacts. The second presentation will focus on key components in the request for proposal for a MRI simulator and how to evaluate vendor proposals. MRI safety issues in radiation Oncology, including MRI scanner Zones (4-zone design), will be discussed. Basic MR terminologies, important functionalities, and advanced features, which are relevant to radiation therapy, will be discussed. In the third presentation, justification of imaging systems for radiation oncology, considerations in room design and construction in a RO department, shared use with diagnostic radiology, staffing needs and training, clinical/research use cases and implementation, will be discussed. The emphasis will be on understanding and bridging the differences between diagnostic and radiation oncology installations, building consensus amongst stakeholders for purchase and use, and integrating imaging technologies into the radiation oncology environment. Learning Objectives: Learn the latest innovations of major imaging systems relevant to radiation therapy Be able to describe important technical specifications of CT, MRI, and PET/CT Understand the process of budget request, equipment justification, comparisons of technical specifications, site visits, vendor selection, and contract development.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2021

Energy Efficiency and Performance Evaluation of Self-Contained, Medium Temperature, Reach-In Refrigerated Display Cases

This project was part of an effort by Commonwealth Edison Company (ComEd) to evaluate the energy and peak demand saving potential of emerging technologies in the Chicago area. This document focuses on the assessment of energy-efficient, medium-temperature, self-contained refrigerated display cases utilizing environmentally friendly refrigerants. The results of this evaluation will be considered by CLEAResult to develop a new energy efficiency rebate measure for ComEd's incentive programs. This rebate measure will become an addition to the Technical Reference Manual (TRM). In 2016, the United Nations passed the Kigali Montreal Protocol Amendment which placed restrictions on certain types of refrigerants. In compliance with this amendment, the US Environmental Protection Agency (EPA) placed a ban on the manufacture of refrigeration systems using hydrofluorocarbons including R134a starting in January 2020. Although the ban has halted manufacture, the EPA continues to allow the use of these refrigerants. Therefore, it is critical to provide incentives for replacing these refrigerants with other environmentally friendly and energy-efficient alternatives. The energy-efficient refrigerator cases evaluated here (referred to as EE Case A and B) contain environmentally-friendly refrigerants in compliance with the EPA hydrofluorocarbon ban. These consist of natural refrigerant propane (R290), and HFC drop-in hydrofluoroolefin R513a, respectively. These cases also contain other energy-efficient components including efficient lighting, more robust evaporator and condenser fans and different-sized heat exchangers. EE Case A is also built with materials that better insulate the case, which improves energy efficiency. To ascertain the energy efficiency contribution of these design components, the consumption of the evaporator and condenser fan motors, compressor, and lighting/controller were evaluated individually. The medium-temperature, self-contained reach-in refrigerated display case was selected due to its widespread use in convenience stores and small supermarkets. Self-contained refrigeration has also seen increased use in restaurants due to curbside pickup during the COVID-19 pandemic. For this study, the refrigerated display cases' performance was evaluated in a controlled environmental chamber at representative indoor dry-bulb and humidity conditions found in supermarkets within ComEd's service territory climate zone. The test method used in this project was foundationally inspired by the ANSI/ASHRAE 72-2018 method of testing. However, modifications to the ANSI/ASHRAE test methodology were implemented to better represent customer operation of the units. In addition to the indoor supermarket conditions, the cases were also evaluated at the "upper target," or environmental conditions used in ANSI/ASHRAE 72-2018. The case total power and case components were metered to obtain their daily power (kW) and energy consumption(kWh). The cases were filled with thermal filler mass to replicate thermal mass of product loading. Additionally, product simulators were used to provide product temperature information. Door actuators were mounted to each of the cases' three doors to replicate regular door openings and effects of shopper traffic.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
DOE OSTI2020

Multilateral Testing Workshop on Relocatable Portal Monitors

The procurement and deployment of radiation detection equipment is a multi-faceted challenge across the globe. Knowledge sharing of the testing methods used to evaluate equipment for deployment scenarios helps improve the understanding of deployed systems by the global community. The United States Department of Energy’s Nuclear Smuggling Detection and Deterrence Office (NSDD) performed a series of characterization measurements in 2019, focused on radiation detection systems that could function as relocatable portal monitors. The capstone activity for this project was a multilateral and cross-disciplinary workshop demonstrating, performing, and refining the techniques used in the characterization measurements with International Atomic Energy Agency (IAEA) and global partners. A group of technical experts including representatives from nine countries, the IAEA, and NSDD gathered at Sandia National Laboratories in Albuquerque, NM during September of 2019 for the Operational and Performance Testing and Evaluation of Relocatable Portals Workshop. Over the course of a week, the group discussed the necessity for and process of developing operational and performance requirements, challenges related to deploying radiation detection systems for the countries in attendance, use cases for deploying relocatable radiation detection equipment, and considerations related to testing equipment for appropriate deployment scenarios. All participants were given the opportunity to have hands-on experience with eleven relocatable systems in executing a limited scope characterization test comprised of six test scenarios. At the conclusion of testing, participants reviewed and presented their findings, and the group as a whole compared and contrasted their experiences. Suggested revisions to the test methods and ideas for further collaborations were discussed. This report discusses the logistical and planning considerations for bringing together experts across disciplines in a multilateral workshop on testing of radiation detectors, as well as presenting the testing methods performed, results, and paths forward. Success of workshops related to technical knowledge transfer and improvement of test methods is key to global technical and scientific support of radiation detection deployments.

Erchinger, Jennifer L.↗
NASA NTRS1977

Solar heating and cooling technical data and systems analysis

The research activities described herein were concentrated on the areas of economics, heating and cooling systems, architectural design, materials characteristics, climatic conditions, educational information packages, and evaluation of solar energy systems and components.

Christensen, D. L.↗
NASA NTRS2016

NASA Collaborative Approach Mitigates Environmentally-Driven Obsolescence

National Aeronautics and Space Administration (NASA) missions, like Department of Defense (DoD) organizations, require the rigorous testing and qualification of critical materials. Obsolescence supply risks created by environmental requirements can affect the cost, schedule and performance of NASA missions and the resilience of critical infrastructure. The NASA Technology Evaluation for Environmental Risk Mitigation (TEERM) Principal Center helps to identify obsolescence supply risks driven by environmental requirements and works proactively with NASA Centers and Programs, the DoD, the European Space Agency (ESA) and other agencies and partners to identify and evaluate environmentally friendly alternatives. TEERM tracks environmental regulations, identifies the potential loss of material availability and works with NASA programs and Centers to evaluate potential impacts through a risk assessment approach. TEERM collaborative projects identify, demonstrate and evaluate commercially viable alternative technologies and materials. A major focus during the Space Shuttle Program was the need to replace ozone depleting substances that were used in spray foam and cleaning applications. The potential obsolescence of coatings containing hexavalent chromium and the risks associated with lead free solder were also of concern for the Space Shuttle and present ongoing risks to new programs such as the Space Launch System. One current project teams NASA and ESA in the evaluation and testing of individual coatings and coating systems as replacements for hexavalent chromium coatings in aerospace applications. The proactive, collaborative approach used by TEERM helps reduce the cost burden on any one team partner, reduces duplication of effort, and enhances the technical quality and overall applicability of the testing and analysis.

environmentall-driven obsolescence↗
NASA NTRS1980

Solar energy system economic evaluation: IBM System 2, Togus, Maine

The economic analysis of the solar energy system, is developed for Torgus and four other sites typical of a wide range of environmental and economic conditions in the continental United States. This analysis is accomplished based on the technical and economic models in the f-chart design procedure with inputs taken on the characteristics of the installed system and local conditions. The results are expressed in terms of the economic parameters of present worth of system cost over a projected twenty year life, life cycle savings, year of positive savings and year of payback for the optimized solar energy system at each of the analysis sites. The sensitivity of the economic evaluation to uncertainties in constituent system and economic variables is also investigated. Results demonstrate that the solar energy system is economically viable at all of the five sites for which the analysis was conducted.

Source record↗
NASA NTRS2004

Fuel Cell/Reformers Technology Development

NASA Glenn Research Center is interested in developing Solid Oxide Fuel Cell for use in aerospace applications. Solid oxide fuel cell requires hydrogen rich feed stream by converting commercial aviation jet fuel in a fuel processing process. The grantee's primary research activities center on designing and constructing a test facility for evaluating injector concepts to provide optimum feeds to fuel processor; collecting and analyzing literature information on fuel processing and desulfurization technologies; establishing industry and academic contacts in related areas; providing technical support to in-house SOFC-based system studies. Fuel processing is a chemical reaction process that requires efficient delivery of reactants to reactor beds for optimum performance, i.e., high conversion efficiency and maximum hydrogen production, and reliable continuous operation. Feed delivery and vaporization quality can be improved by applying NASA's expertise in combustor injector design. A 10 KWe injector rig has been designed, procured, and constructed to provide a tool to employ laser diagnostic capability to evaluate various injector concepts for fuel processing reactor feed delivery application. This injector rig facility is now undergoing mechanical and system check-out with an anticipated actual operation in July 2004. Multiple injector concepts including impinging jet, venturi mixing, discrete jet, will be tested and evaluated with actual fuel mixture compatible with reforming catalyst requirement. Research activities from September 2002 to the closing of this collaborative agreement have been in the following areas: compiling literature information on jet fuel reforming; conducting autothermal reforming catalyst screening; establishing contacts with other government agencies for collaborative research in jet fuel reforming and desulfurization; providing process design basis for the build-up of injector rig facility and individual injector design.

Source record↗
DOE OSTI2023

A Comprehensive Assessment Tool for Low-TRL Current Energy Converters: Preprint

Along with a market-competitive levelized cost of energy, a current energy converter technology strongly benefits from an extensive consideration of socioeconomic, environmental, and regulatory factors early in the design process. As part of a technology performance level assessment, a series of assessment questions and guidance are developed and presented to evaluate an early-stage current energy technology on holistic criteria considering the entire device lifecycle. The assessment represents an accumulation of industry and research experience to date and relies on regular updates to ensure alignment with industry best-practices, regulatory requirements, and up-to-date technical understanding. A cradle-to-grave (materials, manufacturing, installation and deployment, operations and maintenance, and end-of-life) assessment of capabilities and functional requirements for tidal, river, and ocean current technologies has been completed. This work presents the evaluation questions and qualitative performance criteria for current energy converters deployed in tidal, ocean current, and/or river applications. Key considerations related to manufacturing and installation include supply chain robustness, manufacturability and related job creation in the end-user and/or adjacent communities, and the time-to-repayment of the embodied energy debt. During deployment and maintenance operations, the safety of the device and subsystems during disconnect or grid failure, the difficulty and frequency of offshore heavy-lift activities, the avoidance or mitigation of area use conflicts, the sea-states and weather conditions that permit maintenance access, and the availability of contingency plans (should conditions change unexpectedly) are a portion of the considered assessment criteria. Results include the potential impact of early-stage design decisions on the socioeconomic, environmental, and regulatory performance of a technology that allows developers to increase the product value and probability of success, and minimize costly late-stage design iterations through early and broad consideration of factors affecting overall performance and acceptability.

industry support↗
DOE OSTI2023

A Comprehensive Assessment Tool for Low-TRL Current Energy Converters

Along with a market-competitive levelized cost of energy, a current energy converter technology strongly benefits from an extensive consideration of socioeconomic, environmental, and regulatory factors early in the design process. As part of a technology performance level assessment, a series of assessment questions and guidance are developed and presented to evaluate an early-stage current energy technology on holistic criteria considering the entire device lifecycle. The assessment represents an accumulation of industry and research experience to date and relies on regular updates to ensure alignment with industry best-practices, regulatory requirements, and up-to-date technical understanding. A cradle-to-grave (materials, manufacturing, installation and deployment, operations and maintenance, and end-of-life) assessment of capabilities and functional requirements for tidal, river, and ocean current technologies has been completed. This work presents the evaluation questions and qualitative performance criteria for current energy converters deployed in tidal, ocean current, and/or river applications. Key considerations related to manufacturing and installation include supply chain robustness, manufacturability and related job creation in the end-user and/or adjacent communities, and the time-to-repayment of the embodied energy debt. During deployment and maintenance operations, the safety of the device and subsystems during disconnect or grid failure, the difficulty and frequency of offshore heavy-lift activities, the avoidance or mitigation of area use conflicts, the sea-states and weather conditions that permit maintenance access, and the availability of contingency plans (should conditions change unexpectedly) are a portion of the considered assessment criteria. Results include the potential impact of early-stage design decisions on the socioeconomic, environmental, and regulatory performance of a technology that allows developers to increase the product value and probability of success, and minimize costly late-stage design iterations through early and broad consideration of factors affecting overall performance and acceptability.

converter↗
DOE OSTI2022

When Do Efficiency and Demand Flexibility Go Hand-in-hand?

Utilities have been experimenting with integrated demand side management (IDSM) programs since the 2000s. The potential benefits of improved program cost-effectiveness and customer engagement from combining energy efficiency (EE), demand flexibility (DF), and other distributed energy resources into an integrated customer offering have been recognized although there are several known regulatory and program administrative challenges. In addition, as buildings adopt EE measures, the baseline load profile change generally reduces the potential load that can be shed or shifted. This has been a significant technical barrier for customers and program implementers. However, it is a myth that EE always reduces DF. Load change from EE can be time-varying. Therefore, whether EE improves or reduces DF should be evaluated on an individual measure basis accounting for weather dependencies and interactions. For IDSM program design purpose, it is useful to understand how common EE features influence DF and the underlying building physics. In this paper, we use parametric simulations of a prototype medium office building to evaluate how various EE features influence DF, measured by a “demand decrease intensity” (W/ft2) metric. These EE features cover envelope characteristics, internal loads, and airside HVAC system. The parametric analysis shows that some efficient HVAC control measures will increase DF but not the traditional building envelope, lighting, and ventilation-related efficiency measures. These findings contribute to the technical basis for achieving enhanced energy benefits by packaging appropriate HVAC control measures in IDSM program design. Program developers should further validate these results in targeted pilot projects.

Yu, Lili↗
DOE OSTI2015

Enhancing performance assessments using the ASCEM tool-set - 15222

The Office of Soil and Groundwater Remediation within the U.S. Department of Energy's Office of Environmental Management (EM) is supporting development of the Advanced Simulation Capability for Environmental Management (ASCEM). ASCEM is an open source and modular computing framework that incorporates new advances and tools for predicting contaminant fate and transport in natural and engineered systems. ASCEM integrates modeling tools into a common work-flow that facilitates integrated approaches to modeling and site characterization, and enables robust and standardized assessments of performance and risk for EM cleanup and closure activities. The ASCEM project includes collaboration with end users engaged in performance assessments and subsurface simulation. Two working groups are engaged in performance assessment activities at the Hanford Site and Savannah River Site (SRS). The Hanford Site working group is focused on evaluating an alternative conceptual model that includes fine-scale heterogeneities. The baseline conceptual model for the performance assessment includes the large-scale stratigraphy at the site. The working group is applying the ASCEM tool-set to develop and evaluate alternative conceptual models and evaluate the effect of heterogeneities on long-term transport under rainfall-driven conditions. Because the heterogeneous models require long compute times due to increased model complexity, the simulations are implemented on a high-performance computing platform to reduce simulation times. The ASCEM Akuna work-flow enables efficient organization, simulation execution, and processing and visualization of results. Current performance assessments for waste tank closure at the SRS are limited to two-dimensional axi-symmetric representations. The SRS working group is collaborating with the site contractor to address technical review issues by resolving fine-scale tank features and simulating three-dimensional flow with Richards equation for selected closure scenarios using the ASCEM simulator, Amanzi. The Akuna tool-set is being applied to support model setup, sensitivity analysis, uncertainty quantification, and visualization. Both of the ASCEM working groups are addressing issues that cannot readily be evaluated with the existing tools. In these efforts, ASCEM is being used to provide technical underpinnings for ongoing performance assessments. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
NASA NTRS1975

ERTS-1 DCS technical support provided by Wallops Station

Wallops Station accepted the tasks of providing ground truth to several ERTS investigators, operating a DCP repair depot, designing and building an airborne DCP Data Acquisition System, and providing aircraft underflight support for several other investigators. Additionally, the data bank is generally available for use by ERTS and other investigators that have a scientific interest in data pertaining to the Chesapeake Bay area. Working with DCS has provided a means of evaluating the system as a data collection device possibly applicable to ongoing Earth Resources Program activities in the Chesapeake Bay area as well as providing useful data and services to other ERTS investigators. The two areas of technical support provided by Wallops, ground truth stations and repair for DCPs, are briefly discussed.

Smith, R.↗
DOE OSTI2018

E1 Illumination of a Substation Protection System

Sandia’s CRADA partnership with EPRI for calendar year 2017 helped further the technical basis of understanding on the effects to the electric power distribution system infrastructure (i.e., the grid), from a high altitude electromagnetic pulse (HEMP) event. This joint effort yielded evaluation of multiple SCADA relays to very high transient electric fields that were comparable in frequency content to a HEMP event, in multiple equipment configurations that are representative to how the units are fielded and utilized. Both Sandia and EPRI benefit from the data collected. Sandia directly benefits the LDRD effort to address EMP on electrical system infrastructures. EPRI direct benefits the stakeholders they are representing in the power industry. Stakeholders are power generation and distribution companies and equipment manufactures. The results would be used for product improvement and EMP hardening as well as informing the customer base of potential shortfalls of the product to a HEMP event.To better understand the impacts of HEMP on supervisory control and data acquisition (SCADA) systems in typical use at bulk power facilities, Sandia and EPRI has brought together their unique skills and equipment/facilities. EPRI, representing the stakeholders of the power industry, brings technical experience of how supervisory control and data acquisition (SCADA) systems are typically fielded and utilized in real-world applications. With this, EPRI will provides field hardware relating to the SCADA systems. Sandia National Laboratories (Sandia) provides unique test facilities (Sandia’s Electromagnetic Environment Simulator (EMES) and Large Gigahertz Transverse Electromagnetic (GTEM)) and test equipment capabilities to evaluate the SCADA systems to a simulated HEMP event. Sandia brings hands on experience of conducting susceptibility and vulnerability assessments for critical components and systems to high power incident HEMP illumination.

Molina, Luis↗
NASA NTRS2002

TIES for Dummies 3rd Edition (Technology Identification, Evaluation, and Selection) Basic how to's to implement the TIES method

The TIES method is a forecasting environment whereby the decision-maker has the ability to easily assess and trade-off the impact of various technologies without sophisticated and time-consuming mathematical formulations. TIES provides a methodical approach where technically feasible alternatives can be identified with accuracy and speed to reduce design cycle time, and subsequently, life cycle costs, and was achieved through the use of various probabilistic methods, such as Response Surface Methodology and Monte Carlo Simulations. Furthermore, structured and systematic techniques are utilized from other fields to identify possible concepts and evaluation criteria by which comparisons can be made. This objective is achieved by employing the use of Morphological Matrices and Multi-Attribute Decision Making techniques. Through the execution of each step, a family of design alternatives for a given set of customer requirements can be identified and assessed subjectively or objectively. This methodology allows for more information (knowledge) to be brought into the earlier phases of the design process and will have direct implications on the affordability of the system. The increased knowledge allows for optimum allocation of company resources and quantitative justification for program decisions. Finally, the TIES method provided novel results and quantitative justification to facilitate decision making in the early stages of design so as to produce affordable and quality products.

Kirby, Michelle R.↗
DOE OSTI2017

Online Adaptive Hyperthermia Treatment Planning During Locoregional Heating to Suppress Treatment-Limiting Hot Spots

Background: Adequate tumor temperatures during hyperthermia are essential for good clinical response, but excessive heating of normal tissue should be avoided. This makes locoregional heating using phased array systems technically challenging. Online application of hyperthermia treatment planning could help to improve the heating quality. The aim of this study was to evaluate the clinical benefit of online treatment planning during treatment of pelvic tumors heated with the AMC-8 locoregional hyperthermia system. Methods: For online adaptive hyperthermia treatment planning, a graphical user interface was developed. Electric fields were calculated in a preprocessing step using our in-house–developed finite-difference–based treatment planning system. This allows instant calculation of the temperature distribution for user-selected phase-amplitude settings during treatment and projection onto the patient's computed tomographic scan for online visualization. Online treatment planning was used for 14 treatment sessions in 8 patients to reduce the patients' reports of hot spots while maintaining the same level of tumor heating. The predicted decrease in hot spot temperature should be at least 0.5°C, and the tumor temperature should decrease less than 0.2°C. These predictions were compared with clinical data: patient feedback about the hot spot and temperature measurements in the tumor region. Results: In total, 17 hot spot reports occurred during the 14 sessions, and the alternative settings predicted the hot spot temperature to decrease by at least 0.5°C, which was confirmed by the disappearance of all 17 hot spot reports. At the same time, the average tumor temperature was predicted to change on average −0.01°C (range, −0.19°C to 0.34°C). The measured tumor temperature change was on average only −0.02°C (range, −0.26°C to 0.31°C). In only 2 cases the temperature decrease was slightly larger than 0.2°C, but at most it was 0.26°C. Conclusions: Online application of hyperthermia treatment planning is reliable and very useful to reduce hot spots without affecting tumor temperatures.

62 RADIOLOGY AND NUCLEAR MEDICINE↗