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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 19 records
All sourcesNASA NTRSDOE OSTI
NASA NTRS2002

Neural substrates linking balance control and anxiety

This communication provides an update of our understanding of the neurological bases for the close association between balance control and anxiety. New data suggest that a vestibulo-recipient region of the parabrachial nucleus (PBN) contains cells that respond to body rotation and position relative to gravity. The PBN, with its reciprocal relationships with the extended central amygdaloid nucleus, infralimbic cortex, and hypothalamus, appears to be an important node in a primary network that processes convergent vestibular, somatic, and visceral information processing to mediate avoidance conditioning, anxiety, and conditioned fear responses. Noradrenergic and serotonergic projections to the vestibular nuclei also have parallel connections with anxiety pathways. The coeruleo-vestibular pathway originates in caudal locus coeruleus (LC) and provides regionally specialized noradrenergic input to the vestibular nuclei, which likely mediate effects of alerting and vigilance on the sensitivity of vestibulo-motor circuits. Both serotonergic and nonserotonergic pathways from the dorsal raphe nucleus and the nucleus raphe obscurus also project differentially to the vestibular nuclei, and 5-HT(2A) receptors are expressed in amygdaloid and cortical targets of the PBN. It is proposed that the dorsal raphe nucleus pathway contributes to both (a) a tradeoff between motor and sensory (information gathering) aspects of responses to self-motion and (b) a calibration of the sensitivity of affective responses to aversive aspects of motion. This updated neurologic model continues to be a synthetic schema for investigating the neurological and neurochemical bases for comorbidity of balance disorders and anxiety disorders.

Review↗
NASA NTRS2010

Sensory Bias Predicts Postural Stability, Anxiety, and Cognitive Performance in Healthy Adults Walking in Novel Discordant Conditions

We designed a gait training study that presented combinations of visual flow and support surface manipulations to investigate the response of healthy adults to novel discordant sensorimotor conditions. We aimed to determine whether a relationship existed between subjects visual dependence and their scores on a collective measure of anxiety, cognition, and postural stability in a new discordant environment presented at the conclusion of training (Transfer Test). A treadmill was mounted to a motion base platform positioned 2 m behind a large visual screen. Training consisted of three walking sessions, each within a week of the previous visit, that presented four 5-minute exposures to various combinations of support surface and visual scene manipulations, all lateral sinusoids. The conditions were scene translation only, support surface translation only, simultaneous scene and support surface translations in-phase, and simultaneous scene and support surface translations 180 out-of-phase. During the Transfer Test, the trained participants received a 2-minute novel exposure. A visual sinusoidal roll perturbation, with twice the original flow rate, was superimposed on a sinusoidal support surface roll perturbation that was 90 out of phase with the scene. A high correlation existed between normalized torso translation, measured in the scene-only condition at the first visit, and a combined measure of normalized heart rate, stride frequency, and reaction time at the transfer test. Results suggest that visually dependent participants experience decreased postural stability, increased anxiety, and increased reaction times compared to their less visually dependent counterparts when negotiating novel discordant conditions.

Brady, Rachel A.↗
NASA NTRSDate not supplied

Results of the 2022 Mental Health Survey of the Planetary Science Community

The mental health struggles within academia and research are well recognized in the science community and have been further illustrated by the numerous cultural memes and comics (e.g., PhD Comics). With the recent COVID-19 pandemic, mental health has become a topic of concern more so than ever before, as depression and anxiety have become an invisible consequence of social isolation and distancing. In addition, recent social events in the United States have reignited attention towards important social injustices surrounding people of color, women, and LGBTQ+ in academia. If diversity, equity, inclusion, and accessibility are to become major components of improving planetary science, it is also important to understand the mental health status of the community, as it could expose deeply embedded policies, rules, and culture that may hinder any work in sustaining and advancing people belonging to marginalized groups. Studies have been conducted to further understand the mental health of those in academia. These studies have shown that before the pandemic, there was a mental health crisis among graduate students, which became a larger problem with increasing anxiety and depression due to the pandemic. Soon after, the planetary science community recognized this concern in the recent 2023 Planetary Science Decadal White Paper, which proposed that NASA should invest in understanding the scope and impact of mental health problems within the planetary science community and how to address the issue. In this study, we conducted a mental health survey to examine the mental health of the planetary science community. We examined the overall anxiety, depression, and stress severity of the community, rather than diagnosing the community’s condition or determining the proportion of the population having a clinical anxiety, depressive, stress, or trauma-related diagnosis. To emphasize, the results are not intended to make clinical diagnoses, nor are they being used to do so for the purpose of this study.

D Trang↗
NASA NTRS2024

A Survey of the Severity of Mental Health Symptoms in the Planetary Science Community

There is a growing recognition of a mental health crisis within the academic and research communities. Members of the planetary science community have called for healthier work environments to improve mental well-being. As a preliminary step towards improving workplace culture, we sought to determine if the broader mental health crisis extends to planetary science and assess the severity of anxiety, depressive, and stress symptoms. Our 2022 mental health survey of the planetary science community suggests that the severity of anxiety and depressive symptoms in the community is greater than in the general US population. Further, the anxiety and depressive symptoms are more severe for graduate students and postdoctoral researchers than any other career stage. Comparing groups within planetary science, we found that anxiety, depressive, and/or stress symptoms appear greater among marginalized groups, such as women, people of color, and members of the LGBTQ+ community. A mental health problem is impacting the planetary science community. Improving well-being will promote enhanced research quality and productivity.

David Trang↗
NASA NTRS2024

Results of the 2023 Mental Health Survey of the Planetary Science Community

Several recent studies have recognized mental health concerns in academia and in the research field more broadly [e.g., 1,2]. In planetary science, a 2022 survey found that the prevalence of clinically significant anxiety and depressive symptoms among our community is higher than in the general United States public, especially among graduate students, postdoctoral researchers, soft money researchers, and tenure-track faculty. Further, 76% of planetary science participants in the 2022 survey noted that their anxiety and/or depressive symptoms impacted their work, their ability to take care of things at home, and interpersonal relationships. Thus, these symptoms may play a role in decreased research quality and productivity. Interpretations of the 2022 mental health survey of planetary science also noted potential diversity, equity, and inclusion concerns. There were indications of statistically significant greater severities of anxiety, depression, and stress among women, people of color, and those who identify as LGBTQ+ compared to the dominant groups in planetary science. Furthermore, survey participants who identify as LGBTQ+ reported a greater likelihood of considering leaving the planetary science field. With the growing recognition of these mental health concerns, including evidence from the 2022 mental health survey of planetary science, the planetary science community advocated that NASA should further recognize the impact of mental health on science products and composition and work to address these issues including regular monitoring of the health of the community. With the 2023 survey, we shed light on the factors that may contribute to these mental health concerns, which may help the planetary science community and NASA on how to address the issue.

D Trang↗
NASA NTRS2010

Training Enhances Both Locomotor and Cognitive Adaptability to a Novel Sensory Environment

During adaptation to novel gravitational environments, sensorimotor disturbances have the potential to disrupt the ability of astronauts to perform required mission tasks. The goal of this project is to develop a sensorimotor adaptability (SA) training program to facilitate rapid adaptation. We have developed a unique training system comprised of a treadmill placed on a motion-base facing a virtual visual scene that provides an unstable walking surface combined with incongruent visual flow designed to enhance sensorimotor adaptability. The goal of our present study was to determine if SA training improved both the locomotor and cognitive responses to a novel sensory environment and to quantify the extent to which training would be retained. Methods: Twenty subjects (10 training, 10 control) completed three, 30-minute training sessions during which they walked on the treadmill while receiving discordant support surface and visual input. Control subjects walked on the treadmill but did not receive any support surface or visual alterations. To determine the efficacy of training all subjects performed the Transfer Test upon completion of training. For this test, subjects were exposed to novel visual flow and support surface movement, not previously experienced during training. The Transfer Test was performed 20 minutes, 1 week, 1, 3 and 6 months after the final training session. Stride frequency, auditory reaction time, and heart rate data were collected as measures of postural stability, cognitive effort and anxiety, respectively. Results: Using mixed effects regression methods we determined that subjects who received SA training showed less alterations in stride frequency, auditory reaction time and heart rate compared to controls. Conclusion: Subjects who received SA training improved performance across a number of modalities including enhanced locomotor function, increased multi-tasking capability and reduced anxiety during adaptation to novel discordant sensory information. Trained subjects maintained their level of performance over six months.

Bloomberg, J. J.↗
NASA NTRS2011

Cognitive Behavioral Training and Education for Spaceflight Operations

Cognitive behavioral-training (CBT) is an evidence-based practice commonly used to help treat insomnia, and is part of NASA's countermeasure regimen for Fatigue Management. CBT addresses the life style and habits of individuals that are maladaptive to managing stress and fatigue. This includes addressing learned behavioral responses that may cause stress and lead to an increased sense of fatigue. While the initial cause of onset of fatigue in the individual may be no longer present, the perception and engrained anticipation of fatigue persist and cause an exaggerated state of tension. CBT combined with relaxation training allows the individual to unlearn the maladaptive beliefs and behaviors and replace them with routines and techniques that allow cognitive restructuring and resultant relief from stress. CBT allows for elimination in individuals of unwanted ruminating thoughts and anticipatory anxiety by, for example, training the individuals to practice stressful situations in a relaxed state. As a result of CBT, relaxation can be accomplished in many ways, such as progressive muscle relaxation, meditation and guided imagery. CBT is not therapy, but rather the synthesis of behavioral countermeasures. CBT utilizes progressive relaxation as a means of reinforcing educational and cognitive countermeasures. These countermeasures include: masking, elimination of distracting thoughts, anxiety control, split attention, cognitive restructuring and other advanced psychological techniques.

Moonmaw, Ronald↗
NASA NTRS2014

Statistics Clinic

Do you have elevated p‐values? Is the data analysis process getting you down? Do you experience anxiety when you need to respond to criticism of statistical methods in your manuscript? You may be suffering from Insufficient Statistical Support Syndrome (ISSS). For symptomatic relief of ISSS, come for a free consultation with JSC biostatisticians at our help desk during the poster sessions at the HRP Investigators Workshop. Get answers to common questions about sample size, missing data, multiple testing, when to trust the results of your analyses and more. Side effects may include sudden loss of statistics anxiety, improved interpretation of your data, and increased confidence in your results.

Feiveson, Alan H.↗
NASA NTRS2017

Informing Rodent Behavior in Space: Gene Expression and Hyper-Emotionality Following Prenatal Stress

As space exploration pushes our boundaries further away from Earth and for longer durations, we will inevitably require the use of multi-generational studies to continue our expansion. Space is a stressful environment not only due to the deleterious effect of spaceflight on physiology, but also due to confinement, limited social interactions, inherently dangerous circumstances, and many other stresses of an unknown environment. Stress can alter the brain chemistry, and these alterations can affect behavior at all stages of development, but it is especially pronounced during the perinatal period and can have longstanding effects, even into adulthood, which manifest through augmented brain function and psychopathology. This study investigated the nexus of brain chemistry and brain function by observing behavior of adult rats whose mothers were exposed to unpredictable variable prenatal stress (UVPS) while they were in the womb. The UVPS consisted of strobe light, tube restraint, and white noise, and was administered at unpredictable times of the day and also varied in length, both of which were measures taken to prevent habituation to the stressor. The offspring rats were then allowed to reach adulthood and at 90 days were subjected to a series of behavioral tests including novel object, startle response, and an unknown intruder to quantify the adult rats stress response and anxiety. Here we report these results of the behavioral analysis and correlate adult behavioral measures with the expression of genes involved in the hypothalamic-pituitary-adrenal axis, which modulates the animals stress response. We hypothesized that hyper-expression of genes involved in the HPA axis would correlate with the observed anxiety-like behaviors associated with early stress.

Moyer, E. L.↗
NASA NTRS2023

A Review of the Safety of Selective Serotonin Reuptake Inhibitors for Long Duration Spaceflight

Introduction: As humankind ventures further into the depths of space, planning is already underway for long-duration exploration missions that will test the bounds of human performance. Deep space travel will include added risk related to stressors from the isolated, confined, and extreme (ICE) environment that lies outside the boundaries of low-earth orbit. Currently, selective serotonin reuptake inhibitors (SSRIs) are considered the gold standard treatment for many mental health diagnoses including anxiety and depression; however, SSRIs are also associated with several undesired side effects. The utility of non-pharmacologic therapies for the management of behavioral health conditions has not yet been fully explored. Methods: A comprehensive literature search was performed using PubMed and relevant articles pertaining to the psychological impacts of ICE environments, use of SSRIs in spaceflight, side effects associated with SSRIs, and non-pharmacologic treatments for anxiety and depression were reviewed. Over 100 studies were reviewed in total. Results: Reduced bone mineral density, impaired hemostatic function, significant individual variability resulting from gene polymorphisms, and drug-drug interactions are well described adverse effects of SSRIs that may complicate their operational use in the deep space environment. Many non-pharmacologic therapies have been utilized with success for the management of behavioral health conditions in the terrestrial environment that may show promise for long duration missions. Discussion: Although SSRIs have long been considered standard of care treatment for many behavioral health conditions, we cannot trivialize the risk that prolonged pharmacologic therapy may pose. The need to mitigate these risks by exploring alternative non-pharmacologic therapies has never been more relevant.

Charles H Dukes↗
NASA NTRSDate not supplied

The Examination of Individual Factors and AFTE Training Outcomes

Introduction: Motion sickness is common among military aviators. It describes a specific group of symptoms that include epigastric awareness, nausea, pallor, sweating, salivation, and fatigue. Occurrences of these symptoms can pose a significant risk to safety and adversely impact mission success. Accordingly, researchers have developed specific interventions to act as countermeasures. For example, Autogenic Feedback Training Exercise has been empirically validated as a training method that mitigates the impact of motion sickness. However, it remains unclear the extent to which individual factors moderate (or mediate) the effects of this intervention. The examination of individual factors such as interoceptive accuracy (IA) and specific personality traits might provide insight into whom may benefit most from AFTE. Methods: Participants were administered the Big Five Inventory (BFI) and State Trait Anxiety Inventory (STAI). In addition, they were given an interoceptive accuracy task (i.e., heartbeat counting task). The participants’ reported value was then compared to the actual number of heart beats obtained via ECG. Completion of the IA task was followed by pre- AFTE and Post-AFTE rotating chair tests to evaluate motion sickness and the effects of AFTE training. Results: Participants (n=16) were evaluated on IA, personality factors (i.e., BFI & STAI) and performance on the rotating chair. IA was unrelated to personality traits (p > .05), but inversely related to state anxiety post training (p < .05). Finally, IA did not predict performance (i.e., rotations or minutes tolerated ?) on rotating chair F (1, 14) = 1.18, p> .05). Discussion:(1) IA is unrelated to personality traits as measured by BFI and STAI. (2) Individual factors are unrelated to AFTE training outcome. (3) AFTE training can be beneficial for all.

motion sickness↗
NASA NTRS1975

Demographic and psychological variables affecting test subject evaluations of ride quality

Ride-quality experiments similar in objectives, design, and procedure were conducted, one using the U.S. Air Force Total In-Flight Simulator and the other using the Langley Passenger Ride Quality Apparatus to provide the motion environments. Large samples (80 or more per experiment) of test subjects were recruited from the Tidewater Virginia area and asked to rate the comfort (on a 7-point scale) of random aircraft motion typical of that encountered during STOL flights. Test subject characteristics of age, sex, and previous flying history (number of previous airplane flights) were studied in a two by three by three factorial design. Correlations were computed between one dependent measure, the subject's mean comfort rating, and various demographic characteristics, attitudinal variables, and the scores on Spielberger's State-Trait Anxiety Inventory. An effect of sex was found in one of the studies. Males made higher (more uncomfortable) ratings of the ride than females. Age and number of previous flights were not significantly related to comfort ratings. No significant interactions between the variables of age, sex, or previous number of flights were observed.

Duncan, N. C.↗
NASA NTRS1987

Human Adaptation to Isolated and Confined Environments

A study was conducted over seven months in a winter Antarctic isolated and confined environment (ICE). Physiological and psychological data was collected several times a week. Information was collected on a monthly basis on behavior and the use of physical facilities. Adaptation and information indicated that there was a significant decrease in epinephrine and norepinephrine during the middle trimester of the winter. No vital changes were found for blood pressure. Self reports of hostility and anxiety show a linear increase. There were no significant changes in depression during ICE. The physiological and psychological data do not move in a synchronous fashion over time. The data also suggest that both ambient qualities of an ICE and discrete social environmental events, such as the arrival of the summer crew, have an impact on the outcome measures used. It may be most appropiate to develop a model for ICE's that incorporates not only global chronic stressors common to all ICE's but also the role of discrete environmental effects which can minimize or enhance the influence of more chronic stressors. Behavioral adjustment information highlight the importance of developing schedules which balance work and recreational activities.

Evans, Gary W.↗
NASA NTRS1987

Psychiatric Components of a Health Maintenance Facility (HMF) on Space Station

The operational psychiatric requirements for a comprehensive Health Maintenance Facility (HMF) on a permanently manned Space Station are examined. Consideration is given to the psychological health maintenance program designed for the diagnosis of mental distress in astronauts during flight and for prevention of mental breakdown. The types of mental disorders that can possibly affect the astronauts in flight are discussed, including various organic, psychotic, and affective mental disorders, as well as anxiety, adjustment, and somatoform/dissociative disorders. Special attention is given to therapeutic considerations for psychiatric operations on Space Station, such as restraints, psychopharmacology, psychotherapy, and psychosocial support.

Patricia A Santy↗
NASA NTRS1990

Summary of presentation for research on social structure, agreement, and conflict in groups in extreme and isolated environments

Despite a vast amount of research, little is known concerning the effect of group structure, and individuals' understanding of that structure, on conflict in Antarctic groups. The overall objective of the research discussed is to determine the interrelationships of group structure, social cognition, and group function and conflict in isolated and extreme environments. In the two decades following WWII, a large body of research focused on the physiological, psychological, and social psychological factors affecting the functioning of individuals and groups in a variety of extreme and isolated environments in both the Arctic and Antarctic. There are two primary reasons for further research of this type. First, Antarctic polar stations are considered to be natural laboratories for the social and behavioral sciences and provide an opportunity to address certain theoretical and empirical questions concerned with agreement and conflict in social groups in general and group behavior in extreme, isolated environments in particular. Recent advances in the analysis of social networks and intracultural variation have improved the methods and have shifted the theoretical questions. The research is motivated by three classes of questions: (1) What are the characteristics of the social relations among individuals working and living together in extreme and isolated environments?; (2) What do individuals understand about their group, how does that understanding develop, and how is it socially distributed?; and (3) What is the relationship between that understanding and the functioning of the social group? Answers to these questions are important if we are to advance our knowledge of how individuals and groups adapt to extreme environments. Second, although Antarctic winter-over candidates may be evaluated as qualified on the basis of individual characteristics, they may fail to adapt because of certain characteristics of the social group. Consequently, the ability of winter-over-groups to adapt to these extreme conditions has varied dramatically from year to year. In the past, differences in personality, background, and social status have led to conflicts between individuals or cliques precipitating, in turn, an overall decline in morale, failure to accomplish work tasks, and increases in insomnia, depression, anxiety, and alcohol abuse. A better understanding of the role of group structure and social cognition in processes of group adaptation and conflict in Antarctica would contribute towards the revision of existing screening methods, potentially leading to a reduction of group conflict and improved performance of scientific research and support activities. An improved screening protocol for the Antarctic would also have applications for other isolated environments such as scientific outposts and the proposed NASA space station. In sum, this research will (1) contribute significantly to our theoretical understanding of the role of social structure and cognition in the functioning of groups in isolation; (2) complement current work on health and adaptation in polar environments; and (3) provide for models of the formation of group structure that will aid in the development of improved procedures for assembling groups for the Antarctic and other isolated environments (e.g., space stations).

Source record↗