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At least 19 records

Obesity-related cardiovascular risk factors: intervention recommendations to decrease adolescent obesity

The incidence of adolescent obesity is increasing dramatically in the United States with associated risks of hypertension, adverse lipid profiles, and Type II diabetes. Unless reversed, this trend predicts an epidemic of adult cardiovascular disease. Interventions at home, at school, and in the community are required to empower teens to increase physical activity and to modify eating habits. This article describes assessment for obesity-related health problems as well as scientific guidelines and research-based intervention strategies to decrease obesity in adolescents.

Review

Correspondence between theoretical models and dual energy x-ray absorptiometry measurements of femoral cross-sectional growth during adolescence

We have developed an analytical model of long bone cross-sectional ontogeny in which appositional growth of the diaphysis is primarily driven by mechanical stimuli associated with increasing body mass during growth and development. In this study, our goal was to compare theoretical predictions of femoral diaphyseal structure from this model with measurements of femoral bone mineral and geometry by dual energy x-ray absorptiometry. Measurements of mid-diaphyseal femoral geometry and structure were made previously in 101 Caucasian adolescents and young adults 9-26 years of age. The data on measured bone mineral content and calculated section modulus were compared with the results of our analytical model of cross-sectional development of the human femur over the same age range. Both bone mineral content and section modulus showed good correspondence with experimental measurements when the relationships with age and body mass were examined. Strong linear relationships were evident for both parameters when examined as a function of body mass.

NASA Discipline Musculoskeletal

The Role of Game Based Learning in the Health Literacy of African American Adolescent Males

Twenty-first century literacy is more than being able to encode for spelling ability, decode for reading comprehension, and calculate for numeric reasoning. It demands the skills to negotiate the world of technology. Health literacy is lower than general literacy, and general literacy is lower among African American males than the overall population. The authors discuss the prospects of incorporating Game Based Learning approaches into strategies for teaching health literacy. Results of a survey administered to youth to determine their level of involvement in video game playing indicate that key elements must be in place to ensure that a game will be played. These include action, strategy, and entertainment. Future investigation will examine the knowledge level of African American adolescent males of the nexus of certain concepts of climate change and health literacy. Climate change has significant implications for human health. This understanding will produce a scientifically based foundation for curricular and instructional decisions that include GBL. Results of this study will be used to design a video game concept and will contribute to the body of knowledge concerning environmental justice and empower individuals to make informed decisions about their own health and those they influence.

Connell, Judith

P/M superalloys: A troubled adolescent?

The history of powder metallurgy P/M superalloy technology is reviewed with a comment on the state of the art, and speculates on the technology's future potential growth and maturity.

Dreshfield, R. L.

PM superalloys - A troubled adolescent?

The history of powder metallurgy P/M superalloy technology is reviewed with a comment on the state of the art, and speculates on the technology's future potential growth and maturity.

Dreshfield, R. L.

The calcium endocrine system of adolescent rhesus monkeys and controls before and after spaceflight

The calcium endocrine system of nonhuman primates can be influenced by chairing for safety and the weightless environment of spaceflight. The serum of two rhesus monkeys flown on the Bion 11 mission was assayed pre- and postflight for vitamin D metabolites, parathyroid hormone, calcitonin, parameters of calcium homeostasis, cortisol, and indexes of renal function. Results were compared with the same measures from five monkeys before and after chairing for a flight simulation study. Concentrations of 1,25-dihydroxyvitamin D were 72% lower after the flight than before, and more than after chairing on the ground (57%, P < 0.05). Decreases in parathyroid hormone did not reach significance. Calcitonin showed modest decreases postflight (P < 0.02). Overall, effects of spaceflight on the calcium endocrine system were similar to the effects of chairing on the ground, but were more pronounced. Reduced intestinal calcium absorption, losses in body weight, increases in cortisol, and higher postflight blood urea nitrogen were the changes in flight monkeys that distinguished them from the flight simulation study animals.

NASA Center ARC

TOI-712 A System of Adolescent Mini-Neptunes Extending to the Habitable Zone

As an all-sky survey, NASA’s Transiting Exoplanet Survey Satellite (TESS) mission is able to detect the brightest and rarest types of transiting planetary systems, including young planets that enable study of the evolutionary processes that occur within the first billion years. Here we report the discovery of a young, multiplanet system orbiting the bright K4.5V star, TOI-712 ( V = 10.838, M * = 0.733 +0.026 -0.025 M ⨀ , R * = 0.674 ± 0.016 R ⨀ , T eff = 4622 +61 -60 K). From the TESS light curve, we measure a rotation period of 12.48 days and derive an age between about 500 Myr and 1.1 Gyr. The photometric observations reveal three transiting mini-Neptunes ( R b = 2.049 +0.120 -0.080 R ⊕ , R c = 2.701 +0.092 -0.082 R ⊕ , R d = 2.474 +0.090 -0.082 R ⊕ ), with orbital periods of P b = 9.531 days, P c = 51.699 days, and P d = 84.839 days. After modeling the three-planet system, an additional Earth-sized candidate is identified, TOI-712.05 ( P = 4.32 days, R P = 0.81 ± 0.11 R ⊕ ). We calculate that the habitable zone falls between 0.339 and 0.844 au (82.7 and 325.3 days), placing TOI-712 d near its inner edge. Among planetary systems harboring temperate planets, TOI-712 ( T = 9.9) stands out as a relatively young star bright enough to motivate further characterization.

Exoplanets

Building on the foundation for an engineering career

A predictable and preventable hurdle stops a majority of young women from entering the scientific and technical fields. This cuts down the individual's career possibilities and cuts in half the pool of potential U.S. engineers later available to industry. The waste of talent does not advance our country's competitive position. The typical American adolescent girl has acquired all the basic mathematical skills needed to pursue science and math, but, from adolescence on, she does not build the foundation of science and math courses that she would need later in life to work in engineering. Several questions are addressed: Why are some young women stopped cold in their mathematical tracks during adolescence? What is the influence of psychology, including discussion of the personality traits quantifiably shared by women in technical fields? and How should the school system adapt to keep their female charges learning math and science?

White, Susan

Is the spatial distribution of brain lesions associated with closed-head injury in children predictive of subsequent development of posttraumatic stress disorder?

PURPOSE: To determine whether there is an association between the spatial distributions of lesions detected at magnetic resonance (MR) imaging of the brain in children, adolescents, and young adults after closed-head injury (CHI) and development of the reexperiencing symptoms of posttraumatic stress disorder (PTSD). MATERIALS AND METHODS: Data obtained in 94 subjects without a history of PTSD as determined by parental interview were analyzed. MR images were obtained 3 months after CHI. Lesions were manually delineated and registered to the Talairach coordinate system. Mann-Whitney analysis of lesion distribution and PTSD status at 1 year (again, as determined by parental interview) was performed, consisting of an analysis of lesion distribution versus the major symptoms of PTSD: reexperiencing, hyperarousal, and avoidance. RESULTS: Of the 94 subjects, 41 met the PTSD reexperiencing criterion and nine met all three PTSD criteria. Subjects who met the reexperiencing criterion had fewer lesions in limbic system structures (eg, the cingulum) on the right than did subjects who did not meet this criterion (Mann-Whitney, P =.003). CONCLUSION: Lesions induced by CHI in the limbic system on the right may inhibit subsequent manifestation of PTSD reexperiencing symptoms in children, adolescents, and young adults. Copyright RSNA, 2002.

Non-NASA Center

Bone mineral content in normal US whites

Photon absorptiometry with I-125 was used to measure the bone mineral content and the bone width on 763 children between the ages of 5 and 19 years, on 538 adults between the ages of 20 and 49 years, and on 550 adults over the age of 50 years. Measurements were made on the midshaft and the distal end of the radius and the ulna, and on the humerus midshaft. This has permitted analysis of annual bone growth in children, and the rate of change in elderly adults per decade. Male and female children grew at about the same rate until adolescence. After adolescence females grew at a slow rate until the mid-twenties, while males reached adult mineralization by age 20. Males remained relatively constant until the fifties, and females began their decline in the forties.

Mazess, R. B.

Analysis of strontium metabolism in humans on the basis of the Techa river data

Age and sex features of strontium metabolism have been analyzed on studies of the population residing on the banks of the Techa river which was contaminated by fission products during the years 1949-1956. Measurements of 90Sr body burden have been performed since 1974 using a whole-body counter, and these have made it possible to estimate age-specific long-term retention and elimination rates for men and women. Regarding the retention that correlated with the respective maturation ages, distinct sex differences have been observed for adolescents, whereas only postmenopausal women showed a sharp increase of their elimination rates. There were no differences concerning the reproductive ages. Our experimental findings have a clear physiological interpretation and can be used to develop metabolic models for bone-seeking radionuclides.

NASA Discipline Radiation Health

Stochastic parametric skeletal dosimetry model for humans: Anatomical-morphological basis and parameter evaluation

Radiation exposure of the hematopoietic system that results in a radiation dose to bone marrow of more than 100 mGy leads to an increase in the risk of leukemia in humans. Excess relative risk of leukemia was observed in cohorts whose members lived in the territories of the Southern Urals that were radioactively contaminated in the 1950s. As part of the dosimetric support of epidemiological studies of these cohorts, an original methodology for stochastic bone dosimetric modeling was developed, termed the Stochastic Parametric Skeletal Dosimetry (SPSD) model. The purpose of this work was to present the anatomical and morphological bases of the SPSD model, which includes an assessment of the parameters of the microstructure of the trabecular bone in the hematopoietic areas of the human skeleton, as well as a description of the macrostructural division (segmentation) of hematopoietic areas into simple bone segments. As a result, an anatomical-morphological basis of the SPSD model was created based on published data. Data collection work included the analysis of original articles, atlases, manuals, monographs and the formation of primary data files. Data on the duration of hematopoiesis in various parts of the skeleton; and data on age-related changes in the microstructure and linear dimensions of human bones and their segments were analyzed. The paper describes the full set of parameters to be used for the dosimetric model for newborns, children aged 1, 5 and 10 years, as well as for adolescents aged 15 years and adults; for the latter, sex differences in bone size were considered. In total, the SPSD model includes 289 unique basic (bone) phantom segments, each of which is described by 7 or more parameters describing the microstructure, thickness of the cortical layer and linear dimensions. Population variability was estimated for each parameter. The approach to SPSD modeling, i.e., the use of simple geometric shapes, was successfully verified using independent datasets on bone masses and volumes.

Science & Technology - Other Topics

WiDS Livermore Datathon 2025

The WiDS Datathon 2025 requires participants to build a model to predict both an individual’s sex and their ADHD diagnosis using functional brain imaging data of children and adolescents and their socio-demographic, emotions, and parenting information. The task is to create a multi-outcome model to predict two target variables: 1) ADHD (1=yes or 0=no) and 2) female (1=yes or 0=no).

59 BASIC BIOLOGICAL SCIENCES

A multiwavelength investigation of the supernova remnant IC 443

Multiwavelength observations of the supernova remnant IC 443 at radio, infrared, optical, ultraviolet, and X-ray wavelengths are presented. This morphological study of IC 443 presents a detailed picture of an adolescent supernova remnant in a multiphase interstellar medium. Radio observations show that better than 80 percent of the continuum emission at 18 cm is in a large-scale (greater than 18 arcmin) component. Decomposition of the infrared data shows that radiatively heated dust, shocked blackbody dust emission, and infrared line emission are all important components of the observed IRAS fluxes. The morphology of the IC 443 region is consistent with a supernova blast in an interstellar medium with a nonuniform distribution of clouds. The bright northeast rim and the great extent of the remnant to the southwest are most easily explained by a cloud filling factor which is greatest in the northeast and falls off toward the southwest.

Mufson, S. L.