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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 19 records

Shape deformation of the organ of Corti associated with length changes of outer hair cell

Cochlear outer hair cells (OHC) are commonly assumed to function as mechanical effectors as well as sensory receptors in the organ of Corti (OC) of the inner ear. OHC in vitro and in organ explants exhibit mechanical responses to electrical, chemical or mechanical stimulation which may represent an aspect of their effector process that is expected in vivo. A detailed description, however, of an OHC effector operation in situ is still missing. Specifically, little is known as to how OHC movements influence the geometry of the OC in situ. Previous work has demonstrated that the motility of isolated OHCs in response to electrical stimulation and to K(+)-gluconate is probably under voltage control and causes depolarisation (shortening) and hyperpolarization (elongation). This work was undertaken to investigate if the movements that were observed in isolated OHC, and which are induced by ionic stimulation, could change the geometry of the OC. A synchronized depolarization of OHC was induced in guinea pig cochleae by exposing the entire OC to artificial endolymph (K+). Subsequent morphometry of mid-modiolar sections from these cochleae revealed that the distance between the basilar membrane (BM) and the reticular lamina (RL) had decreased considerably. Furthermore, in the three upper turns OHC had significantly shortened in all rows. The results suggest that OHC can change their length in the organ of Corti (OC) thus deforming the geometry of the OC. The experiments reveal a tonic force generation within the OC that may change the position of RL and/or BM, contribute to damping, modulate the BM-RL-distance and control the operating points of RL and sensory hair bundles. Thus, the results suggest active self-adjustments of cochlear mechanics by slow OHC length changes. Such mechanical adjustments have recently been postulated to correspond to timing elements of animal communication, speech or music.

Non-NASA Center↗

Real time data acquisition for expert systems in Unix workstations at Space Shuttle Mission Control

A distributed system of proprietary engineering-class workstations is incorporated into NASA's Space Shuttle Mission-Control Center to increase the automation of mission control. The Real-Time Data System (RTDS) allows the operator to utilize expert knowledge in the display program for system modeling and evaluation. RTDS applications are reviewed including: (1) telemetry-animated communications schematics; (2) workstation displays of systems such as the Space Shuttle remote manipulator; and (3) a workstation emulation of shuttle flight instrumentation. The hard and soft real-time constraints are described including computer data acquisition, and the support techniques for the real-time expert systems include major frame buffers for logging and distribution as well as noise filtering. The incorporation of the workstations allows smaller programming teams to implement real-time telemetry systems that can improve operations and flight testing.

Muratore, John F.↗

The 'Biologically-Inspired Computing' Column

The field of Biology changed dramatically in 1953, with the determination by Francis Crick and James Dewey Watson of the double helix structure of DNA. This discovery changed Biology for ever, allowing the sequencing of the human genome, and the emergence of a "new Biology" focused on DNA, genes, proteins, data, and search. Computational Biology and Bioinformatics heavily rely on computing to facilitate research into life and development. Simultaneously, an understanding of the biology of living organisms indicates a parallel with computing systems: molecules in living cells interact, grow, and transform according to the "program" dictated by DNA. Moreover, paradigms of Computing are emerging based on modelling and developing computer-based systems exploiting ideas that are observed in nature. This includes building into computer systems self-management and self-governance mechanisms that are inspired by the human body's autonomic nervous system, modelling evolutionary systems analogous to colonies of ants or other insects, and developing highly-efficient and highly-complex distributed systems from large numbers of (often quite simple) largely homogeneous components to reflect the behaviour of flocks of birds, swarms of bees, herds of animals, or schools of fish. This new field of "Biologically-Inspired Computing", often known in other incarnations by other names, such as: Autonomic Computing, Pervasive Computing, Organic Computing, Biomimetics, and Artificial Life, amongst others, is poised at the intersection of Computer Science, Engineering, Mathematics, and the Life Sciences. Successes have been reported in the fields of drug discovery, data communications, computer animation, control and command, exploration systems for space, undersea, and harsh environments, to name but a few, and augur much promise for future progress.

Hinchey, Mike↗

AAH Cage Out-Link and In-Link Antenna Characterization

This final report encapsulates the accomplishments of the third year of work on an Advanced Biotelemetry System (ABTS). Overall MU/ABTS project objectives are to provide a biotelemetry system that can collect data from and send commands to an implanted biotransceiver. This system will provide for studies of rodent development in space. The system must be capable of operating in a metal animal cage environment. An important goal is the development of a small, "smart", micropower, implantable biotransceiver with eight-channel data output and single channel command input capabilities with the flexibility for easy customization for a variety of physiologic investigations. The NASA Ames/Marquette University Joint Research work has been devoted to the system design of such a new state of the art biotelemetry system, having multiple physiologic inputs, and bi-directional data transfer capabilities. This work has provided a successful prototype system that connects, by two-way radio links, an addressable biotelemetry system that provides communication between an animal biotelemeter prototype and a personal computer. The operational features of the prototype system are: (1) two-way PCM communication with implanted biotelemeter; (2) microcontroller based biotelemeter; (3) out-link: wideband FSK (60 kBaud); (4) in-link: OOK (2.4 kbaud); (5) septum antenna arrays (In/Out-Links); and (6) personal computer data interface. The important requirement of this third year's work, to demonstrate two-way communication with transmit and receive antennas inside the metal animal cage, has been successfully accomplished. The advances discussed in this report demonstrate that the AAH cage antenna system can provide Out-link and In-link capability for the ABTS bi-directional telemetry system, and can serve as a benchmark for project status. Additions and enhancements to the most recent (April 1997) prototype cage and antenna have been implemented. The implementation, testing, and documentation was accomplished at the Biotelemetry Laboratory at Marquette University with Out-Link (slot) antenna design assistance was provided.

Jeutter, Dean C.↗

AAH Cage Out-Link and In-Link Antenna Characterization

This final report encapsulates the accomplishments of the third year of work on an Advanced Biotelemetry System (ABTS). Overall MU/ABTS project objectives are to provide a biotelemetry system that can collect data from and send commands to an implanted biotransceiver. This system will provide for studies of rodent development in space. The system must be capable of operating in a metal animal cage environment. An important goal is the development of a small, "smart", micropower, -channel data output and single channel command implantable biotransceiver with eight input capabilities with the flexibility for easy customization for a variety of physiologic investigations. The NASA Ames/Marquette University Joint Research work has been devoted to the system design of such a new state of the art biotelemetry system, having multiple physiologic inputs, and bi-directional data transfer capabilities. This work has provided a successful prototype system that connects, by two-way radio links, an addressable biotelemetry system that provides communication between an animal biotelemeter prototype and a personal computer. The operational features of the prototype system are listed below: Two-Way PCM Communication with Implanted Biotelemeter Microcontroller Based Biotelemeter Out-Link: Wideband FSK (60 kbaud) In-Link: OOK (2.4 kbaud) Septum Antenna Arrays (In/Out-Links) Personal Computer Data Interface The important requirement of this third year's work, to demonstrate two-way communication with transmit and receive antennas inside the metal animal cage, has been successfully accomplished. The advances discussed in this report demonstrate that the AAH cage antenna system can provide Out-link and In-link capability for the ABTS bi-directional telemetry system, and can serve as a benchmark for project status.

Jeutter, Dean C.↗

Nonconscious intelligence in the universe

Animals lacking humanoid intelligence have evolved systems indistinguishable in function, if not in structure, from systems built by humans. Although radio communication has never been verified in animals, it is completely feasible biologically. If such systems are present in non-intelligent organisms on other planets, then our chances of detecting life in the universe by current SETI methods are greatly enhanced.

NASA Discipline Exobiology↗

Cross-cutting concepts to transform agricultural research

Agriculture is an important link to many issues that challenge society today, including adaptation to and mitigation of climate change, food security, and communicable and non-communicable diseases in animals and humans. Transformation of agriculture and food systems has become a priority for a range of federal agencies and global organizations. It is imperative that food and agricultural researchers effectively harness the global convergence of priorities to overcome research “silos” through deep and sustained systemic change. Herein, we identify intersections in federal and global initiatives encompassing climate adaptation and mitigation; human health and nutrition; animal health and welfare; food safety and security; and equity and inclusion. Many agencies and organizations share these priorities, but efforts to address them remain uncoordinated and opportunities for collaboration untapped. Based on the interconnectedness of the identified priority areas, we present a research framework to catalyze agricultural transformation, beginning with the research enterprise. We propose that transformation in agricultural research should incorporate (1) innovation, (2) integration, (3) implementation, and (4) evaluation. This framework provides approaches for food and agricultural research to contribute to sustainable, flexible, and coordinated transformation in the agricultural sector.

60 APPLIED LIFE SCIENCES↗

Analytical Framework for Rodent/NHP Data Set Utilization to Inform Human CNS Risk Estimation

Objectives Review and inform on tactics to analyze & communicate data from animal research (e.g., rodents, mini-pigs, NHPs, et al) exposed to single and combinations of spaceflight hazards, using NASA’s Human System Risk Board (HSRB) process for the Behavioral Medicine Risk - To quantitatively inform Behavioral Medicine Risk posture - i.e., likelihood (L) and consequence (C) - To help inform estimation of crew health standards for operational task performance (i.e., Fitness For Duty, Space Permissible Exposure Levels, Permissible Operational Limits).

Brain↗

Interactive Visualization of Computational Fluid Dynamics using Mosaic

The Web provides new Methods for accessing Information world-wide, but the current text-and-pictures approach neither utilizes all the Web's possibilities not provides for its limitations. While the inclusion of pictures and animations in a paper communicates more effectively than text alone, It Is essentially an extension of the concept of "publication." Also, as use of the Web increases putting images and animations online will quickly load even the "Information Superhighway." We need to find forms of communication that take advantage of the special nature of the Web. This paper presents one approach: the use of the Internet and the Mosaic interface for data sharing and collaborative analysis. We will describe (and In the presentation, demonstrate) our approach: using FAST (Flow Analysis Software Toolkit), a scientific visualization package, as a data viewer and interactive tool called from MOSAIC. Our intent is to stimulate the development of other tools that utilize the unique nature of electronic communication.

Clucas, Jean↗

Emergence of Relations and the Essence of Learning: A Review of Sidman's Equivalence Relations and Behavior: A Research Story

Sidman addresses two very important questions in Equivalence Relations and Behavior: A Research Story: What are the bases of behavioral competence? And how do units of learning become related? The book recounts the story of how an understanding of emergent relations and competencies was achieved through studies in his teaching-research program with mentally retarded subjects. Although children normally accrue vast networks of relations between stimuli and events, those with mental retardation typically do not. Consequently, by learning how to establish those networks, Sidman and his students contribute richly both to the cultivation of competencies by their subjects and, more generally, to an understanding of real-world human behavior. The basic equivalence paradigm affords the subject feedback and reinforcement for very specific choices during training, but the test is not for those choices! Rather, tests for equivalence look for new choices, ones seemingly quite foreign to the training regimen. The tests for equivalence relations entail presentations of stimuli that were the options for conditional choice during reinforced training. In tests of equivalence, correct choices are novel; hence, they have never been reinforced during training. The study of equivalence relations can encourage the emergence of new perspectives that are more symbiotic than competitive. In full acknowledgment of the important role and contributions made by those who identify themselves as experimental analysts of behavior, it is timely that rapprochements be worked toward, as indeed they are, to meld that perspective with others of our time. Both our research methods and our expectations about the nature of the learning process and the abilities of our subjects can delimit what they might learn and what we, in turn, learn about their learning. The text will be of great value for instruction at the upper-division and graduate levels. Its impact will be substantial, for it defines an important advance in our efforts to understand the richness of behavior in both humans and nonhuman animals. Although not presented to that end, the book might also serve to bridge communications with other groups of animal researchers whose interests lie more in a comparative or ethological framework.

Rumbaugh, Duane M.↗

Mars Observer Press Conference JPL

The Mars Observer mission spacecraft was primarily designed for exploring Mars and the Martian environment. The Mars Observer was launched on September 25, 1992. The spacecraft was lost in the vicinity of Mars on August 21, 1993 when the spacecraft began its maneuvering sequence for Martian orbital insertion. This videotape shows a press briefing, held after the spacecraft had not responded to attempts to communicate with it, to explain to the press the problems and the steps that were being taken to re-establish communication with the spacecraft. The communications had been shutdown prior to the orbital insertion burn to protect the instruments. At the time of the press conference, the communications system was still not operational, and attempts were being made to re-establish communication. Bob McMillan of the Public Affairs Office at JPL gives the initial announcement of the continuing communication problem with the spacecraft. Mr. McMillan introduces William Piotrowski, acting director of solar system exploration, who reiterates that there is indeed no communication with the Observer spacecraft. He is followed by Glenn Cunningham, the Project Manager of the Mars Observer who speaks about the attempts to re-establish contact. Mr. Cunningham is followed by Satenios Dallas, the Mission Manager for the Mars Observer Project, who speaks about the sequence of events leading up to the communication failure, and shows an animated video presenting the orbital insertion maneuvers. The briefing was then opened up for questions from the assembled press, both at JPL and at the other NASA Centers. The questions are about the possible reasons for the communication failure, and the attempts to restore communications with the spacecraft. Dr. Arden L. Albee, chief scientist for the Mars Observer Mission, joins the other panel members to answer questions. At the end of the press briefing the animation of the Mars orbital insertion is shown again.

Source record↗

2020 State of the Science Report, Chapter 4: Risk to Marine Animals from Underwater Noise Generated by Marine Renewable Energy Devices

In all ocean environments, desirable locations for wave and tidal energy development have multiple natural sources of sound (e.g., waves, wind, and sediment transport), varying levels of anthropogenic and biological noise, and measurement quality challenges (e.g., flow-noise, self-noise). Many marine animals rely on sound for biological functions, including communication, social interaction, orientation, foraging, and evasion. The extent to which marine animals detect and produce sound varies by frequency (spanning roughly four decades from 10 Hz to 100 kHz) and is taxa-specific. Because of the relatively limited data available, hearing sensitivity is often generalized to taxonomic groups (e.g., cetaceans that have low-frequency hearing specialization). https://tethys.pnnl.gov/publications/state-of-the-science-2020-chapter-4-underwater-noise

54 ENVIRONMENTAL SCIENCES↗

Remote sensing and human health: new sensors and new opportunities

Since the launch of Landsat-1 28 years ago, remotely sensed data have been used to map features on the earth's surface. An increasing number of health studies have used remotely sensed data for monitoring, surveillance, or risk mapping, particularly of vector-borne diseases. Nearly all studies used data from Landsat, the French Systeme Pour l'Observation de la Terre, and the National Oceanic and Atmospheric Administration's Advanced Very High Resolution Radiometer. New sensor systems are in orbit, or soon to be launched, whose data may prove useful for characterizing and monitoring the spatial and temporal patterns of infectious diseases. Increased computing power and spatial modeling capabilities of geographic information systems could extend the use of remote sensing beyond the research community into operational disease surveillance and control. This article illustrates how remotely sensed data have been used in health applications and assesses earth-observing satellites that could detect and map environmental variables related to the distribution of vector-borne and other diseases.

Satellite Communications↗

Individual recognition between mother and infant bats (Myotis)

The recognition process and the basis for that recognition, in brown bats, between mother and infant are analyzed. Two parameters, ultrasonic communication and olfactory stimuli, are investigated. The test animals were not allowed any visual contact. It was concluded that individual recognition between mother and infant occurred. However, it could not be determined if the recognition was based on ultrasonic signals or olfactory stimuli.

Turner, D.↗

Life Sciences Division Spaceflight Hardware

The Ames Research Center (ARC) is responsible for the development, integration, and operation of non-human life sciences payloads in support of NASA's Gravitational Biology and Ecology (GB&E) program. To help stimulate discussion and interest in the development and application of novel technologies for incorporation within non-human life sciences experiment systems, three hardware system models will be displayed with associated graphics/text explanations. First, an Animal Enclosure Model (AEM) will be shown to communicate the nature and types of constraints physiological researchers must deal with during manned space flight experiments using rodent specimens. Second, a model of the Modular Cultivation System (MCS) under development by ESA will be presented to highlight technologies that may benefit cell-based research, including advanced imaging technologies. Finally, subsystems of the Cell Culture Unit (CCU) in development by ARC will also be shown. A discussion will be provided on candidate technology requirements in the areas of specimen environmental control, biotelemetry, telescience and telerobotics, and in situ analytical techniques and imaging. In addition, an overview of the Center for Gravitational Biology Research facilities will be provided.

Yost, B.↗