Search NASA⌕ Search

SEARCH · Search NASA

Results for “Animals”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 records
All sourcesNASA NTRSDOE OSTI
NASA NTRSDate not supplied

Developing A Space-Based Solution to Increase Accessibility, Quality, and Utility of Animal Tracking Data for Research and Management: the Internet of Animals Project

Animal tracking technology has advanced dramatically over the last several decades, but researchers and wildlife managers still encounter technological roadblocks in the study of animal movement and acquisition of animal movement data. For example, we still lack technology that provides automated high-resolution data for small animals that travel long distances, which limits our ability to answer both theoretical and applied questions about these species. In response to these needs, NASA has initiated a five-year study of potential space-based solutions that could provide global low-latency tracking of small migratory animals. This study, named Internet of Animals (IOA), aims to 1) systematically assess the needs of animal movement researchers and ecological managers, 2) design a next-generation space-based animal tracking system, i.e. an ‘Internet of Animals’ or IoA, to meet those needs, and 3) developing science and technology needed to link animal tracking data to the many other dimensions of biodiversity that can now be mapped from space using remote sensing. Here, we present results from the first IOA workshop, which highlighted the diverse needs of researchers and managers working across systems and realms. We also provide opportunities for the community to engage in the future.

remote sensing↗
NASA NTRS1994

EM-ANIMATE: A Computer Program for Displaying and Animating Electromagnetic Near-Field and Surface-Current Solutions: Video Supplement to NASA Technical Memorandum 4539

In this video, several examples of electromagnetic field and surface-current animation sequences are shown to demonstrate the visualization capabilities of the EM-ANIMATE computer program. These examples show the animation of total and scattered electric near fields from test bodies of a flat plate, a corner reflector, and a sphere. These test cases show the electric-field behavior caused by different scattering mechanisms through the animation of electromagnetic data from the EM-ANIMATE routine.

Hom, Kam W.↗
NASA NTRS1987

Growth hormone secretion during space flight and evaluation of the physiological responses of animals held in the research animal holding facility

The spaceflight of the Research Animal Holding Facility (RAHF) on the Space Laboratory 3 (SL 3) provided the opportunity to evaluate the suitability of the RAHF for housing and maintaining experimental animals during spaceflight, and to determine changes in the secretion of growth hormone during spaceflight. Using ground-based studies the following were investigated: the optimum conditions for creating gravitational force on space flight animals; neural pathways that may play a role in the space flight syndrome; and the time course of muscle atrophy due to hypodynamia and hypokenesia in hindlimb-suspended animals and the role of growth hormone in these processes.

Fast, Thomas N.↗
NASA NTRS1994

Development of an Advanced Animal Habitat for Spaceflight

It is necessary to fly a group-housed animals for many Life Science spaceflight studies. Currently, group-housed rodents are flown aboard the shuttle in the Animal Enclosure Module (AEM). Although the AEM has been used successfully for a number of flights, it has significant limitations in the number of animals it can accommodate, limited flight duration, passive temperature control and limited in flight data acquisition capability. An Advanced Animal Habitat (AAH) is being developed, which can be flown on the shuttle middeck, both spacelab and spacehab shuttle payload modules, and the space station. The AAH is designed to house 12 rats or 30 mice for up to 30 days. The AAH will have active temperature control, a window mechanism to facilitate video monitoring/recording of the animals, and biotelemetry capabilities. In addition, the design will permit access to the animals for experimental manipulations in space. The AAH can be refitted to experiment-specific requirements as needed. In initial 7-day hardware tests 12 male rats and 10 female mice show no adverse affects with respect to final body and organ weights as compared to vivarium. controls. The Advanced Animal Habitat will provide the science community opportunities to perform a greater variety of studies for longer duration in the microgravity environment than the current Animal Enclosure Module.

Baer, L.↗
NASA NTRS2020

Astro-animation - A case study of art and science education

Art and science are different ways of exploring the world, but together they have the potential to be thought-provoking, facilitate a science‐society dialogue, raise public awareness of science and develop an understanding of art. For several years, we have been teaching an astro-animation class at the Maryland Institute College of Art as a collaboration between students and NASA scientists. Working in small groups, the students create short animations based on the research of the scientists who are going to follow the projects as mentors. By creating these animations, students bring the power of their imagination to see the research of the scientists through a different lens. Astro-animation is an undergraduate-level course jointly taught by an astrophysicist and an animator. In this article, we present the motivation behind the class, describe the details of how it is carried out and discuss the interactions between artists and scientists. We describe how such a programme offers an effective way for art students, not only to learn about science but to have a glimpse of ‘science in action’. The students have the opportunity to become involved in the process of science as artists, as observers first and potentially through their own art research. Every year, one or more internships at NASA Goddard Space Flight Center have been available for our students in the summer. Two students describe their experiences undertaking these internships and how science affects their creation of animations for this programme and in general. We also explain the genesis of our astro-animation programme, how it is taught in our animation department and we present the highlights of an investigation of the effectiveness of this programme we carried out with the support of an NEA research grant. In conclusion, we discuss how the programme may grow in new directions, such as contributing to informal STE(A)M learning.

Laurence Arcadias↗
NASA NTRS2001

HZE particle radiation induces tissue-specific and p53-dependent mutagenesis in transgenic animals

Transgenic animals, with the integrated target gene, provide a unique approach for measuring and characterizing mutations in any tissue of the animal. We are using the plasmid-based lacZ transgenic mice with different p53 genetic background to examine radiation-induced genetic damage resulting from exposure to heavy particle radiation. We measured lacZ mutation frequencies (MF) in the brain and spleen tissues at various times after exposing animals to an acute dose of 1 Gy of 1GeV/amu iron particles. MF in the spleen of p53+/+ animals increased up to 2.6-fold above spontaneous levels at 8 weeks post irradiation. In contrast, brain MF from the same animals increased 1.7-fold above controls in the same period. In the p53-/- animals, brain MF increased to 2.2-fold above spontaneous levels at 1 week after treatment, but returned to control levels thereafter. Radiation also induced alterations in the spectrum of mutants in both tissues, accompanied by changes in the frequency of mutants with deletions extending past the transgene into mouse genomic DNA. Our results indicate that the accumulation of transgene MF after radiation exposure is dependant on the tissue examined as well as the p53 genetic background of the animals.

Non-NASA Center↗
NASA NTRSDate not supplied

The Internet of Animals: How to Use NASA's Assets and Computing for Biodiversity and Conservation Needs

There are many internal and external drivers of animal movement. For example, where might an animal go if it’s hungry, or how will it move if it’s really windy? The Internet of Animals project aims to combine animal telemetry data with earth observations to better support applied ecological management, architect a next-generation space-based animal tracking system and develop technology that can link to biodiversity and habitats via remote sensing. In this talk, Morgan Gilmour will provide an overview of movement ecology, remote sensing, and how earth observations with NASA’s assets can help inform biodiversity and conservation. Morgan is a Research Scientist at NASA Ames Research Center. Her research focuses on marine animal movement ecology. Some recent projects include investigating animal movement in relation to marine protected areas in the central Pacific and quantifying at-sea habitat use by albatrosses.

animal telemetry↗
NASA NTRS1978

Reproducibility of toxicity test data as a function of mouse strain, animal lot, and operator

The toxicity screening test method developed at the University of San Francisco was evaluated for reproducibility. The variables addressed were strain of mouse, lot of animals, and operator. There was a significant difference in response between Swiss Webster mice and ICR mice, with the latter exhibiting greater resistance. These two strains of mice are not interchangeable in this procedure. Variation between individual animals was significant and unavoidable. In view of this variation, between-lot and between-operator variations appear to have no practical significance. The significant variation between individual animals stresses the need for average values based on at least four animals, and preferably values based on at least two experiments and eight animals. Efforts to compare materials should be based on the evaluation of relatively simple responses using substantial numbers of animals, rather than on elaborate evaluation of single animals

Hilado, C. J.↗
NASA NTRS1996

Light-Emitting Diodes (LED) for Primary Animal Habitat Lighting in Highly Controlled Environments

Significant alterations in Biological Clock responses have been reported following sidereal time changes (e.g., Jet-lag), and exposure to microgravity (e.g., daytime sleepiness). Additionally, light reduces circulating melatonin (spectral specificity greatest between 450-500 nm). It was hypothesized that LEDs can replace the current light sources used in zero gravity and terrestrial research laboratories because of their small size, low mass, low energy consumption and long functional life. This report evaluates the capacity of LEDs to entrain the circadian system of rats as judged by measurement of overt behavioral circadian rhythms (activity, feeding, drinking). These data were collected in highly controlled environments similar to the shuttle Animal Enclosure Modules. Two groups were compared: control - animals exposed to standard cool-white fluorescent lights, and test - animals exposed to LEDs with a spectral power distribution matching the fluorescent lights. Gross locomotor activity, feeding and drinking frequencies were continuously monitored and stored at 10 minute intervals. Animals were exposed to the following photoperiods: 28 days of 12L:12D, 19 days of 24L:0D and 16 days of 12L:12D. Light intensities tested varied between 0.1 to 100 lux. Rats received food and water ad libitum, and temperature and humidity were controlled throughout the study. The general health status of all rats was acceptable for each day of this study. No incidents of aggressive behavior were observed. Growth, locomotor activity, food and water consumption were comparable for all groups of animals, i.e, the circadian characteristics of the animals under these conditions were comparable. These results indicate that LED arrays are as effective in maintaining circadian rhythm stability as the commonly used cool-white fluorescent light sources. LEDs with their flexible spectrum, low energy requirements and minimal heat production have advantages for some chronopharmacology studies and for microgravity animal habitats.

Winget, C. M.↗
NASA NTRS2010

The History of the Animal Care Program at NASA Johnson Space Center

This slide presentation reviews the work of the Animal Care Program (ACP). Animals have been used early in space exploration to ascertain if it were possible to launch a manned spacecraft. The program is currently involved in many studies that assist in enhancing the scientific knowledge of the effect of space travel. The responsibilities of the ACP are: (1) Organize and supervise animal care operations & activities (research, testing & demonstration). (2) Maintain full accreditation by the International Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) (3) Ensure protocol compliance with IACUC recommendations (4) Training astronauts for in-flight animal experiments (5) Maintain accurate & timely records for all animal research testing approved by JSC IACUC (6) Organize IACUC meetings and assist IACUC members (7) Coordinate IACUC review of the Institutional Program for Humane Care and Use of Animals (every 6 mos)

Khan-Mayberry, Noreen↗
NASA NTRS2015

Software Development: 3D Animations and Creating User Interfaces for Realistic Simulations

My fall 2015 semester was spent at the Lyndon B. Johnson Space Center working in the Integrated Graphics, Operations, and Analysis Laboratory (IGOAL). My first project was to create a video animation that could tell the story of OMICS. OMICS is a term being used in the field of biomedical science to describe the collective technologies that study biological systems, such as what makes up a cell and how it functions with other systems. In the IGOAL I used a large 23 inch Wacom monitor to draw storyboards, graphics, and line art animations. I used Blender as the 3D environment to sculpt, shape, cut or modify the several scenes and models for the video. A challenge creating this video was to take a term used in biomedical science and describe it in such a way that an 8th grade student can understand. I used a line art style because it would visually set the tone for what we thought was an educational style. In order to get a handle on the perspective and overall feel for the animation without overloading my workspace, I split up the 2 minute animation into several scenes. I used Blender's python scripting capabilities which allowed for the addition of plugins to add or modify tools. The scripts can also directly interact with the objects to create naturalistic patterns or movements. After collecting the rendered scenes, I used Blender's built-in video editing workspace to output the animation. My second project was to write software that emulates a physical system's interface. The interface was to simulate a boat, ROV, and winch system. Simulations are a time and cost effective way to test complicated data and provide training for operators without having to use expensive hardware. We created the virtual controls with 3-D Blender models and 2-D graphics, and then add functionality in C# using the Unity game engine. The Unity engine provides several essential behaviors of a simulator, such as the start and update functions. A framework for Unity, which was developed in the lab, provided a way to place the different widgets on the virtual console dock and have them resize correctly based on the window dimensions.. My task in this project was to create the controls and visualizations for the data coming in from the simulator for the boat portion of the project. I wrote a class for each control window to handle the functionality of that widget. I implemented 11 widgets that make up the ship portion of the simulator. The members of the lab were each masters of their craft and I'm glad I had the opportunity to learn from them. I learned to plan strategically so I could finish this project on time. I allotted time for storyboarding, development, and refinement. In regards to animating I learned to use modifiers like lattice, boolean and build deformers. I also learned how to animate with drivers, how to use the dope sheet, and how to use the graph editor. In coding I learned to limit the chances for bugs by privatizing functions that should be exclusive to their class. I learned how to use the GIT repository to commit, stash and pull the latest build. I learned a bit of everything because I had the chance to see the entire application development process from the artwork, to the implementation.

Gordillo, Orlando Enrique↗
NASA NTRS2005

Use of animal models for space flight physiology studies, with special focus on the immune system

Animal models have been used to study the effects of space flight on physiological systems. The animal models have been used because of the limited availability of human subjects for studies to be carried out in space as well as because of the need to carry out experiments requiring samples and experimental conditions that cannot be performed using humans. Experiments have been carried out in space using a variety of species, and included developmental biology studies. These species included rats, mice, non-human primates, fish, invertebrates, amphibians and insects. The species were chosen because they best fit the experimental conditions required for the experiments. Experiments with animals have also been carried out utilizing ground-based models that simulate some of the effects of exposure to space flight conditions. Most of the animal studies have generated results that parallel the effects of space flight on human physiological systems. Systems studied have included the neurovestibular system, the musculoskeletal system, the immune system, the neurological system, the hematological system, and the cardiovascular system. Hindlimb unloading, a ground-based model of some of the effects of space flight on the immune system, has been used to study the effects of space flight conditions on physiological parameters. For the immune system, exposure to hindlimb unloading has been shown to results in alterations of the immune system similar to those observed after space flight. This has permitted the development of experiments that demonstrated compromised resistance to infection in rodents maintained in the hindlimb unloading model as well as the beginning of studies to develop countermeasures to ameliorate or prevent such occurrences. Although there are limitations to the use of animal models for the effects of space flight on physiological systems, the animal models should prove very valuable in designing countermeasures for exploration class missions of the future.

Review↗
NASA NTRS2017

Advantage of Animal Models with Metabolic Flexibility for Space Research Beyond Low Earth Orbit

As the world's space agencies and commercial entities continue to expand beyond Low Earth Orbit (LEO), novel approaches to carry out biomedical experiments with animals are required to address the challenge of adaptation to space flight and new planetary environments. The extended time and distance of space travel along with reduced involvement of Earth-based mission support increases the cumulative impact of the risks encountered in space. To respond to these challenges, it becomes increasingly important to develop the capability to manage an organism's self-regulatory control system, which would enable survival in extraterrestrial environments. To significantly reduce the risk to animals on future long duration space missions, we propose the use of metabolically flexible animal models as "pathfinders," which are capable of tolerating the environmental extremes exhibited in spaceflight, including altered gravity, exposure to space radiation, chemically reactive planetary environments and temperature extremes. In this report we survey several of the pivotal metabolic flexibility studies and discuss the importance of utilizing animal models with metabolic flexibility with particular attention given to the ability to suppress the organism's metabolism in spaceflight experiments beyond LEO. The presented analysis demonstrates the adjuvant benefits of these factors to minimize damage caused by exposure to spaceflight and extreme planetary environments. Examples of microorganisms and animal models with dormancy capabilities suitable for space research are considered in the context of their survivability under hostile or deadly environments outside of Earth. Potential steps toward implementation of metabolic control technology in spaceflight architecture and its benefits for animal experiments and manned space exploration missions are discussed.

metabilic flexibility↗
NASA NTRS2017

Advantage of Animal Models with Metabolic Flexibility for Space Research Beyond Low Earth Orbit

As the worlds space agencies and commercial entities continue to expand beyond Low Earth Orbit (LEO), novel approaches to carry out biomedical experiments with animals are required to address the challenge of adaptation to space flight and new planetary environments. The extended time and distance of space travel along with reduced involvement of Earth-based mission support increases the cumulative impact of the risks encountered in space. To respond to these challenges, it becomes increasingly important to develop the capability to manage an organisms self-regulatory control system, which would enable survival in extraterrestrial environments. To significantly reduce the risk to animals on future long duration space missions, we propose the use of metabolically flexible animal models as pathfinders, which are capable of tolerating the environmental extremes exhibited in spaceflight, including altered gravity, exposure to space radiation, chemically reactive planetary environments and temperature extremes.In this report we survey several of the pivotal metabolic flexibility studies and discuss the importance of utilizing animal models with metabolic flexibility with particular attention given to the ability to suppress the organism's metabolism in spaceflight experiments beyond LEO. The presented analysis demonstrates the adjuvant benefits of these factors to minimize damage caused by exposure to spaceflight and extreme planetary environments. Examples of microorganisms and animal models with dormancy capabilities suitable for space research are considered in the context of their survivability under hostile or deadly environments outside of Earth. Potential steps toward implementation of metabolic control technology in spaceflight architecture and its benefits for animal experiments and manned space exploration missions are discussed.

metabolic flexibility↗
NASA NTRS1980

The development of a Space Shuttle Research Animal Holding Facility

The ability to maintain the well being of experiment animals is of primary importance to the successful attainment of life sciences flight experiment goals. To assist scientists in the conduct of life sciences flight experiments, a highly versatile Research Animal Holding Facility (RAHF) is being developed for use on Space Shuttle/Spacelab missions. This paper describes the design of the RAHF system, which in addition to providing general housing for various animal species, approximating the environment found in ground based facilities, is designed to minimize disturbances of the specimens by vehicle and mission operations. Life-sustaining capabilities such as metabolic support and environmental control are provided. RAHF is reusable and is a modular concept to accommodate animals of different sizes. The basic RAHF system will accommodate a combination of 24 500-g rats or 144 mice or a mixed number of rats and mice. An alternative design accommodates four squirrel monkeys. The entire RAHF system is housed in a single ESA rack. The animal cages are in drawers which are removable for easy access to the animals. Each cage contains a waste management system, a feeding system and a watering system all of which will operate in zero or one gravity.

Jagow, R. B.↗
NASA NTRS1993

Animation of multi-flexible body systems and its use in control system design

Animation can greatly assist the structural dynamicist and control system analyst with better understanding of how multi-flexible body systems behave. For multi-flexible body systems, the structural characteristics (mode frequencies, mode shapes, and damping) change, sometimes dramatically with large angles of rotation between bodies. With computer animation, the analyst can visualize these changes and how the system responds to active control forces and torques. A characterization of the type of system we wish to animate is presented. The lack of clear understanding of the above effects was a key element leading to the development of a multi-flexible body animation software package. The resulting animation software is described in some detail here, followed by its application to the control system analyst. Other applications of this software can be determined on an individual need basis. A number of software products are currently available that make the high-speed rendering of rigid body mechanical system simulation possible. However, such options are not available for use in rendering flexible body mechanical system simulations. The desire for a high-speed flexible body visualization tool led to the development of the Flexible Or Rigid Mechanical System (FORMS) software. This software was developed at the Center for Simulation and Design Optimization of Mechanical Systems at the University of Iowa. FORMS provides interactive high-speed rendering of flexible and/or rigid body mechanical system simulations, and combines geometry and motion information to produce animated output. FORMS is designed to be both portable and flexible, and supports a number of different user interfaces and graphical display devices. Additional features have been added to FORMS that allow special visualization results related to the nature of the flexible body geometric representations.

Juengst, Carl↗