SEARCH · Search NASA
Results for “BIFURCATION”
Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Efficient and reversible electron bifurcation with either normal or inverted potentials at the bifurcating cofactor
A longstanding mystery surrounding electron bifurcation is the significance of inverted (or “crossed”) reduction potentials of the two-electron bifurcating cofactor. Using a many-electron open-system kinetic model, we show that reversible and efficient electron bifurcation is possible without inverted reduction potentials at the bifurcating site if the absolute value of the difference between first and second reduction potentials of the bifurcating species is sufficiently large (on the scale of the redox-potential span of the high- and low-potential branches). Surprisingly, the case with strong, normally ordered potentials at the bifurcating cofactor can produce electron bifurcation that is just as effective as the case with strongly inverted potentials. Lastly, this finding amplifies the puzzle surrounding the recruitment of inverted potentials in the few well-characterized bifurcating systems of nature and suggests that electron bifurcating cofactors without strongly inverted potentials may yet be discovered.
Spatially quasi-periodic bifurcations from periodic traveling water waves and a method for detecting bifurcations using signed singular values
We present a method of detecting bifurcations by locating zeros of a signed version of the smallest singular value of the Jacobian. This enables the use of quadratically convergent root-bracketing techniques or Chebyshev interpolation to locate bifurcation points. Only positive singular values have to be computed, though the method relies on the existence of an analytic or smooth singular value decomposition (SVD). The sign of the determinant of the Jacobian, computed as part of the bidiagonal reduction in the SVD algorithm, eliminates slope discontinuities at the zeros of the smallest singular value. We use the method to search for spatially quasi-periodic traveling water waves that bifurcate from large-amplitude periodic waves. The water wave equations are formulated in a conformal mapping framework to facilitate the computation of the quasi-periodic Dirichlet-Neumann operator. We find examples of pure gravity waves with zero surface tension and overhanging gravity-capillary waves. In both cases, the waves have two spatial quasi-periods whose ratio is irrational. We follow the secondary branches via numerical continuation beyond the realm of linearization about solutions on the primary branch to obtain traveling water waves that extend over the real line with no two crests or troughs of exactly the same shape. The pure gravity wave problem is of relevance to ocean waves, where capillary effects can be neglected. Such waves can only exist through secondary bifurcation as they do not persist to zero amplitude. The gravity-capillary wave problem demonstrates the effectiveness of using the signed smallest singular value as a test function for multi-parameter bifurcation problems. This test function becomes mesh independent once the mesh is fine enough.
Mechanistic insights into energy conservation by flavin-based electron bifurcation
Explore the source record for details and available documents.
2D analysis of tokamak divertor-plasma detachment-bifurcation with operational parameters and geometries
UEDGE simulations with density scans for various input power, transport coefficients and outer poloidal leg length are performed to study the conditions for the existence of a bifurcation-like drop of T e at the outer strike point, commonly referred to as a detachment cliff, when transitioning to a detached plasma from an attached plasma in the outer divertor as the upstream density increases (McLean et al., 2015). The simulation results show that a detachment cliff tends to occur with a higher power input regardless of diffusivities and leg length. Further analysis of change of plasma profiles at a cliff indicate that, in addition to the sharp reduction of the E x B drift fluxes in the outer divertor studied in Jaervinen et al., (2018), the substantial change of the Mach number in the outer divertor and the decrease of the outer mid-plane T e due to the radiation front moving across the separatrix into the confinement region above the X-point consistently occur for all UEDGE density scans that have a detachment cliff. UEDGE time-dependent simulation of the evolution of a detachment cliff shows that the rapid increase of radiation above the X-point occurs in a time scale of ~0.3–0.5, which could possibly be the trigger for the formation of a detachment cliff, quicker than the Mach number change in a time scale of ~1 ms and the drop of T e in a time scale of ~2–3 ms in the outer divertor.
Enzymatic β-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA
Explore the source record for details and available documents.
Bifurcations of Coupled Electron-Phonon Modes in an Antiferromagnet Subjected to a Magnetic Field
Not Available
Bifurcations and degenerate periodic points in a three dimensional chaotic fluid flow
Analysis of the periodic points of a conservative periodic dynamical system uncovers the basic kinematic structure of the transport dynamics and identifies regions of local stability or chaos. While elliptic and hyperbolic points typically govern such behaviour in 3D systems, degenerate (parabolic) points also play an important role. These points represent a bifurcation in local stability and Lagrangian topology. In this study, we consider the ramifications of the two types of degenerate periodic points that occur in a model 3D fluid flow. (1) Period-tripling bifurcations occur when the local rotation angle associated with elliptic points is reversed, creating a reversal in the orientation of associated Lagrangian structures. Even though a single unstable point is created, the bifurcation in local stability has a large influence on local transport and the global arrangement of manifolds as the unstable degenerate point has three stable and three unstable directions, similar to hyperbolic points, and occurs at the intersection of three hyperbolic periodic lines. The presence of period-tripling bifurcation points indicates regions of both chaos and confinement, with the extent of each depending on the nature of the associated manifold intersections. (2) The second type of bifurcation occurs when periodic lines become tangent to local or global invariant surfaces. This bifurcation creates both saddle–centre bifurcations which can create both chaotic and stable regions, and period-doubling bifurcations which are a common route to chaos in 2D systems. We provide conditions for the occurrence of these tangent bifurcations in 3D conservative systems, as well as constraints on the possible types of tangent bifurcation that can occur based on topological considerations.
Electron Bifurcating Hydrogenases
The importance of electron-bifurcating enzymes is manifest by their ability to maximize energy efficiency. Specifically, they couple a downhill oxidation-reduction (redox) reaction with an uphill redox reaction. Since the rapid increase in the discovery of bifurcating enzymes starting in 2008, there has been interest in incorporating their mechanistic principles into artificial/semiartificial systems to drive chemically challenging reactions. This has yet to be achieved, partly because the details of electron bifurcation, i.e. mechanisms, are largely elusive. Nevertheless, much progress has been made in understanding reactivities, structures, and some mechanistic aspects of these enzymes. Notable examples are electron-bifurcating hydrogenases, which are the focus of this chapter. The chapter is organized as follows. Section 11.1 provides an overview of hydrogenases and electron bifurcation. In Section 11.2, some physiological roles of electron-bifurcating hydrogenases are highlighted. Additionally, electron-bifurcating subunit compositions and biochemical reactivities are comprehensively tabulated, and some key points/considerations about these are noted. In Section 11.3, we discuss the known structures of these enzymes, which provide insight into their complex arrangements of redox cofactors, such as iron-sulfur clusters. Also provided are tabulations and discussions of some biophysical properties of the cofactors. In Section 11.4, we discuss the mechanistic proposals of these enzymes, which are primarily based on structural information. Areas of research that are much needed are outlined in Section 11.5. We conclude on the note that what is learned from electron-bifurcating hydrogenases has applicability to other bifurcating enzymes, nonbifurcating analogs, and mechanistic enzymology at large.
An Abundant and Diverse New Family of Electron Bifurcating Enzymes With a Non-canonical Catalytic Mechanism
Microorganisms utilize electron bifurcating enzymes in metabolic pathways to carry out thermodynamically unfavorable reactions. Bifurcating FeFe-hydrogenases (HydABC) reversibly oxidize NADH (E′∼−280 mV, under physiological conditions) and reduce protons to H 2 gas (E°′−414 mV) by coupling this endergonic reaction to the exergonic reduction of protons by reduced ferredoxin (Fd) (E′∼−500 mV). We show here that HydABC homologs are surprisingly ubiquitous in the microbial world and are represented by 57 phylogenetically distinct clades but only about half are FeFe-hydrogenases. The others have replaced the hydrogenase domain with another oxidoreductase domain or they contain additional subunits, both of which enable various third reactions to be reversibly coupled to NAD + and Fd reduction. We hypothesize that all of these enzymes carry out electron bifurcation and that their third substrates can include hydrogen peroxide, pyruvate, carbon monoxide, aldehydes, aryl-CoA thioesters, NADP + , cofactor F 420 , formate, and quinones, as well as many yet to be discovered. Some of the enzymes are proposed to be integral membrane-bound proton-translocating complexes. These different functionalities are associated with phylogenetically distinct clades and in many cases with specific microbial phyla. We propose that this new and abundant class of electron bifurcating enzyme be referred to as the Bfu family whose defining feature is a conserved bifurcating BfuBC core. This core contains FMN and six iron sulfur clusters and it interacts directly with ferredoxin (Fd) and NAD(H). Electrons to or from the third substrate are fed into the BfuBC core via BfuA. The other three known families of electron bifurcating enzyme (abbreviated as Nfn, EtfAB, and HdrA) contain a special FAD that bifurcates electrons to high and low potential pathways. The Bfu family are proposed to use a different electron bifurcation mechanism that involves a combination of FMN and three adjacent iron sulfur clusters, including a novel [2Fe-2S] cluster with pentacoordinate and partial non-Cys coordination. The absolute conservation of the redox cofactors of BfuBC in all members of the Bfu enzyme family indicate they have the same non-canonical mechanism to bifurcate electrons. A hypothetical catalytic mechanism is proposed as a basis for future spectroscopic analyses of Bfu family members.
A Fundamental Study of Bifurcation Acoustic Treatment Effects on Aft-Fan Engine Noise
Increasing air traffic and more stringent aircraft noise regulations continue to expand requirements on aircraft noise levels for conventional and unconventional aircraft configurations. A major component of the overall aircraft noise is the sound associated with the propulsion system mounted in the engine nacelle. Acoustic liners mounted in the aircraft engine nacelles provide a significant portion of the current fan noise reduction. However, they must be further optimized if challenging noise reduction goals are to be achieved. One location within the aft bypass duct that may be an excellent candidate for increased attention is the acoustic treatment on the engine bifurcations (i.e., engine pylon and lower bifurcation). This paper presents the continuation of a fundamental study of the effects of bifurcation treatment on simulated aft fan noise and the validation of numerical tools to predict such effects. Five bifurcation configurations (four treated and one hardwall) were fabricated and tested in the NASA Langley Curved Duct Test Rig. Results show that mode scattering may occur due to both the presence of the bifurcation, as well as variable impedance distributions on the bifurcation surface. Future work will also include optimization of bifurcation treatments for testing in the Curved Duct Test Rig. These initial results are promising and this work provides valuable information for further study and improvement of the performance of bifurcation acoustic treatments.
A Fundamental Study of Bifurcation Acoustic Treatment Effects on Aft-Fan Engine Noise
Increasing air traffic and more stringent aircraft noise regulations continue to expand requirements on aircraft noise levels for conventional and unconventional aircraft configurations. A major component of the overall aircraft noise is the sound associated with the propulsion system mounted in the engine nacelle. Acoustic liners mounted in the aircraft engine nacelles provide a significant portion of the current fan noise reduction. However, they must be further optimized if challenging noise reduction goals are to be achieved. One location within the aft bypass duct that may be an excellent candidate for increased attention is the acoustic treatment on the engine bifurcations (i.e., engine pylon and lower bifurcation). This paper presents the continuation of a fundamental study of the effects of bifurcation treatment on simulated aft fan noise and the validation of numerical tools to predict such effects. Five bifurcation configurations (four treated and one hardwall) were fabricated and tested in the NASA Langley Curved Duct Test Rig. Results show that mode scattering may occur due to both the presence of the bifurcation, as well as variable impedance distributions on the bifurcation surface. Future work will also include optimization of bifurcation treatments for testing in the Curved Duct Test Rig. These initial results are promising and this work provides valuable information for further study and improvement of the performance of bifurcation acoustic treatments.
A Fundamental Study of Bifurcation Acoustic Treatment Effects on Aft-Fan Engine Noise
Increasing air traffic and more stringent aircraft noise regulations continue to expand requirements on aircraft noise levels for conventional and unconventional aircraft configurations. A major component of the overall aircraft noise is the sound associated with the propulsion system mounted in the engine nacelle. Acoustic liners mounted in the aircraft engine nacelles provide a significant portion of the current fan noise reduction. However, they must be further optimized if challenging noise reduction goals are to be achieved. One location within the aft bypass duct that may be an excellent candidate for increased attention is the acoustic treatment on the engine bifurcations (i.e., engine pylon and lower bifurcation). This paper presents the continuation of a fundamental study of the effects of bifurcation treatment on simulated aft fan noise and the validation of numerical tools to predict such effects. Five bifurcation configurations (four treated and one hardwall) were fabricated and tested in the NASA Langley Curved Duct Test Rig. Results show that mode scattering may occur due to both the presence of the bifurcation, as well as variable impedance distributions on the bifurcation surface. Future work will also include optimization of bifurcation treatments for testing in the Curved Duct Test Rig. These initial results are promising and this work provides valuable information for further study and improvement of the performance of bifurcation acoustic treatments.
Congruent Bifurcation Angles in River Delta and Tributary Channel Networks
We show that distributary channels on river deltas exhibit a mean bifurcation angle that can be understood using theory developed in tributary channel networks. In certain cases, tributary network bifurcation geometries have been demonstrated to be controlled by diffusive groundwater flow feeding incipient bifurcations, producing a characteristic angle of 72°. We measured 25 unique distributary bifurcations in an experimental delta and 197 bifurcations in 10 natural deltas, yielding a mean angle of 70.4°±2.6° (95% confidence interval) for field-scale deltas and a mean angle of 68.3°±8.7° for the experimental delta, consistent with this theoretical prediction. The bifurcation angle holds for small scales relative to channel width length scales. Furthermore, the experimental data show that the mean angle is 72° immediately after bifurcation initiation and remains relatively constant over significant time scales. Although distributary networks do not mirror tributary networks perfectly, the similar control and expression of bifurcation angles suggests that additional morphodynamic insight may be gained from further comparative study.
Multiple Bifurcated Covered Self-Expanding Metallic Stents for Complex Tracheobronchial Fistulas or Stenosis
Objective: We aimed to determine the safety and feasibility of bifurcated covered self-expanding stents for the treatment of complex tracheobronchial fistulas or stenosis. Methods: Twenty-eight patients were treated by multiple bifurcated covered airway stents (Micro-Tech Co. Ltd., Nanjing, China), including 18 cases of gastrobronchial or gastrotracheal fistula, 6 cases of bronchopleural fistula and 4 cases of severe tracheobronchial stenosis. The large bifurcated covered stent was placed at the main carina, and the small stents were inserted into primary right carina or secondary left carina. Clinical and imaging data were retrospectively analyzed. Results: Stents were successfully inserted in 27 patients at the first attempt. In total, 29 large bifurcated covered stents, 27 small bifurcated covered stents and 5 small bifurcated covered single-plugged stents were inserted. All patients with fistula could resume eating without coughing after the procedure. No perioperative death or severe complications occurred. Two patients underwent stent removal due to intolerance of stenting; the clinical success rate was 93% (26/28). Nineteen complications were found in 12 patients; 8 patients needed stent removal or replacement, for a major complication rate of 29% (8/28). Eight patients underwent successful stent removal due to complications. Fifteen patients died of tumors and one patient died of pulmonary infection. The median survival was 33 months. Fistula recurrence was found in one patient 5 months after stenting, and second small bifurcated covered stent was inserted. Conclusions: Multiple bifurcated covered metallic stenting is effective and safe for complex tracheobronchial fistulas or stenosis, with good symptom palliation.