SEARCH · Search NASA

Results for “Biological processes and phenomena”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

SourceResearch connectionFrom yearThrough year

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 records

All sources NASA NTRS DOE OSTI

NASA NTRS1976

Space processing payload experiment requirements

An overview is given of the definition of research requirements and derivation of engineering design requirements for a group of 77 representative applications of space processing. Representative requirements are documented for applied research in space on biological processes, chemical/fluid phenomena, solidification processes, and glass/ceramics processes. Design requirements for payload equipment to accommodate these research requirements are presented in engineering terms, such as power requirements, schematic diagrams, etc. In addition, a summary of the 77 applied research topics is included.

Taylor, K. R.↗

NASA NTRS2004

High Sensitivity, Low Power Nano Sensors and Devices for Chemical Sensing

The chemical sensor market has been projected to grow to better than $40 billion dollars worldwide within the next 10 years. Some of the primary motivations to develop nanostructured chemical sensors are monitoring and control of environmental pollution; improved diagnostics for consumption; improvement in measurement precision and accuracy; and improved detection limits for Homeland security, battlefield environments, and process and quality control of industrial applications. In each of these applications, there is demand for sensitivity, selectivity and stability of environmental and biohazard detection and capture beyond what is currently commercially available. Nanotechnology offers the ability to work at the molecular level, atom by atom, to create large structures with fundamentally new molecular organization. It is essentially concerned with materials, devices, and systems whose structures and components exhibit novel and significantly improved physical, chemical and biological properties, phenomena, and process control due to their nanoscale size. One such nanotechnology-enabled chemical sensor has been developed at NASA Ames leveraging nanostructures, such as single walled carbon nanotubes (SWNTs) and metal oxide nanobelts or nanowires, as a sensing medium bridging a pair of interdigitated electrodes (IDE) realized through a silicon-based microfabrication and micromachining technique. The DE fingers are fabricated on a silicon substrate using standard photolithography and thin film metallization techniques. It is noteworthy that the fabrication techniques employed are not confined to the silicon substrate. Through spin casting and careful substrate selection (i.e. clothing, glass, polymer, etc.), additional degrees of freedom can be exploited to enhance sensitivity or to conform to unique applications. Both in-situ growth of nanostructured materials and casting of nanostructured dispersions were used to produce analogous chemical sensing devices.

Li, Jing↗

NASA NTRS1984

Marketing the use of the space environment for the processing of biological and pharmaceutical materials

The perceptions of U.S. biotechnology and pharmaceutical companies concerning the potential use of the space environment for the processing of biological substances was examined. Physical phenomena that may be important in space-base processing of biological materials are identified and discussed in the context of past and current experiment programs. The capabilities of NASA to support future research and development, and to engage in cooperative risk sharing programs with industry are discussed. Meetings were held with several biotechnology and pharmaceutical companies to provide data for an analysis of the attitudes and perceptions of these industries toward the use of the space environment. Recommendations are made for actions that might be taken by NASA to facilitate the marketing of the use of the space environment, and in particular the Space Shuttle, to the biotechnology and pharmaceutical industries.

Source record↗

NASA NTRSDate not supplied

High Sensitive and Low Power Nanosensors for Space and Terrestrial Applications

Nanotechnology offers the ability to work at the molecular level, atom by atom, to create large structures with fundamentally new molecular organization. It is essentially concerned with materials, devices, and systems whose structures and components exhibit novel and significantly improved physical, chemical and biological properties, phenomena, and process control due to their nanoscale size. A nanosensor technology has been developed at NASA Ames using nanostructure, single walled carbon nanotubes (SWNTs). The nanosensors have achieved low detection limit of chemicals in the concentration range of ppm to ppb. Due to large surface area, low surface energy barrier and high thermal and mechanical stability, nanostructured chemical sensors offer higher sensitivity, lower power consumption and a more robust solution than most state-of-the-art systems making them attractive for space and terrestrial applications. An example of a sensor module, the first space flown nano device, will be introduced in this presentation. Such sensors have drawn attention from space community for global weather monitoring, space exploration, life search in the universe, and launch pad fuel leak detection and in-flight cabin air and life support system monitoring, and engine operation monitoring. Additionally, the wireless capability of such sensors can be leveraged to network mobile and fixed-base detection and warning systems for civilian population centers, military bases and battlefields, as well as other high-value or high-risk assets and areas in industry.

Jing Li↗

NASA NTRS1992

Toward a microgravity research strategy

Recommendations of the Committee on Microgravity Research (CMGR) of the Space Studies Board of the National Research Council are found in the Summary and Recommendations in the front of the report. The CMGR recommends a long-range research strategy. The main rationale for the microgravity research program should be to improve our fundamental scientific and technical knowledge base, particularly in the areas that are likely to lead to improvements in processing and manufacturing on earth. The CMGR recommends research be categorized as Biological science and technology, Combustion, Fluid science, Fundamental phenomena, Materials, and Processing science and technology. The committee also recommends that NASA apply a set of value criteria and measurement indicators to define the research and analysis program more clearly. The CMGR recommends that the funding level for research and analysis in microgravity science be established as a fixed percentage of the total program of NASA's Microgravity Science and Applications Division in order to build a strong scientific base for future experiments. The committee also recommends a cost-effective approach to experiments. Finally the CMGR recommends that a thorough technical review of the centers for commercial development of space be conducted to determine the quality of their activities and to ascertain to what degree their original mission has been accomplished.

Source record↗

NASA NTRS1992

The Role of Lidars in Global Change Research

Recent research has solidified a view of the Earth as a global scale interactive system with complex chemical, physical, biological, and dynamical processes that link the ocean, atmosphere, land, and marine terrestrial living organisms. An important aspect of Earth System Science studies in the future is the need to observe simultaneously the physical, chemical, biological, and dynamical processes involved in highly coupled phenomena such as those mentioned. Lidars operating from the surface, aircraft, and satellites provide a powerful observational technique to study the processes and observe trends important to global change. Lidar observations have already played important roles in helping understand processes controlling stratospheric ozone and aerosols, tropospheric clouds, water vapor, ozone, gaseous pollutants, and aerosols, and winds and temperatures throughout the atmosphere. In this paper the author reviews the science of global change and highlights the potential roles for lidar in studying the Earth system.

Prinn, Ronald G.↗

NASA NTRS1982

Fluid models and simulations of biological cell phenomena

The dynamics of coated droplets are examined within the context of biofluids. Of specific interest is the manner in which the shape of a droplet, the motion within it as well as that of aggregates of droplets can be controlled by the modulation of surface properties and the extent to which such fluid phenomena are an intrinsic part of cellular processes. From the standpoint of biology, an objective is to elucidate some of the general dynamical features that affect the disposition of an entire cell, cell colonies and tissues. Conventionally averaged field variables of continuum mechanics are used to describe the overall global effects which result from the myriad of small scale molecular interactions. An attempt is made to establish cause and effect relationships from correct dynamical laws of motion rather than by what may have been unnecessary invocation of metabolic or life processes. Several topics are discussed where there are strong analogies droplets and cells including: encapsulated droplets/cell membranes; droplet shape/cell shape; adhesion and spread of a droplet/cell motility and adhesion; and oams and multiphase flows/cell aggregates and tissues. Evidence is presented to show that certain concepts of continuum theory such as suface tension, surface free energy, contact angle, bending moments, etc. are relevant and applicable to the study of cell biology.

Greenspan, H. P.↗

NASA NTRS2009

Evolutionary Computing Methods for Spectral Retrieval

A methodology for processing spectral images to retrieve information on underlying physical, chemical, and/or biological phenomena is based on evolutionary and related computational methods implemented in software. In a typical case, the solution (the information that one seeks to retrieve) consists of parameters of a mathematical model that represents one or more of the phenomena of interest. The methodology was developed for the initial purpose of retrieving the desired information from spectral image data acquired by remote-sensing instruments aimed at planets (including the Earth). Examples of information desired in such applications include trace gas concentrations, temperature profiles, surface types, day/night fractions, cloud/aerosol fractions, seasons, and viewing angles. The methodology is also potentially useful for retrieving information on chemical and/or biological hazards in terrestrial settings. In this methodology, one utilizes an iterative process that minimizes a fitness function indicative of the degree of dissimilarity between observed and synthetic spectral and angular data. The evolutionary computing methods that lie at the heart of this process yield a population of solutions (sets of the desired parameters) within an accuracy represented by a fitness-function value specified by the user. The evolutionary computing methods (ECM) used in this methodology are Genetic Algorithms and Simulated Annealing, both of which are well-established optimization techniques and have also been described in previous NASA Tech Briefs articles. These are embedded in a conceptual framework, represented in the architecture of the implementing software, that enables automatic retrieval of spectral and angular data and analysis of the retrieved solutions for uniqueness.

Terrile, Richard↗

NASA NTRS1992

High level cognitive information processing in neural networks

Two related research efforts were addressed: (1) high-level connectionist cognitive modeling; and (2) local neural circuit modeling. The goals of the first effort were to develop connectionist models of high-level cognitive processes such as problem solving or natural language understanding, and to understand the computational requirements of such models. The goals of the second effort were to develop biologically-realistic model of local neural circuits, and to understand the computational behavior of such models. In keeping with the nature of NASA's Innovative Research Program, all the work conducted under the grant was highly innovative. For instance, the following ideas, all summarized, are contributions to the study of connectionist/neural networks: (1) the temporal-winner-take-all, relative-position encoding, and pattern-similarity association techniques; (2) the importation of logical combinators into connection; (3) the use of analogy-based reasoning as a bridge across the gap between the traditional symbolic paradigm and the connectionist paradigm; and (4) the application of connectionism to the domain of belief representation/reasoning. The work on local neural circuit modeling also departs significantly from the work of related researchers. In particular, its concentration on low-level neural phenomena that could support high-level cognitive processing is unusual within the area of biological local circuit modeling, and also serves to expand the horizons of the artificial neural net field.

Barnden, John A.↗

NASA NTRS2007

Automated Knowledge Discovery From Simulators

A computational method, SimLearn, has been devised to facilitate efficient knowledge discovery from simulators. Simulators are complex computer programs used in science and engineering to model diverse phenomena such as fluid flow, gravitational interactions, coupled mechanical systems, and nuclear, chemical, and biological processes. SimLearn uses active-learning techniques to efficiently address the "landscape characterization problem." In particular, SimLearn tries to determine which regions in "input space" lead to a given output from the simulator, where "input space" refers to an abstraction of all the variables going into the simulator, e.g., initial conditions, parameters, and interaction equations. Landscape characterization can be viewed as an attempt to invert the forward mapping of the simulator and recover the inputs that produce a particular output. Given that a single simulation run can take days or weeks to complete even on a large computing cluster, SimLearn attempts to reduce costs by reducing the number of simulations needed to effect discoveries. Unlike conventional data-mining methods that are applied to static predefined datasets, SimLearn involves an iterative process in which a most informative dataset is constructed dynamically by using the simulator as an oracle. On each iteration, the algorithm models the knowledge it has gained through previous simulation trials and then chooses which simulation trials to run next. Running these trials through the simulator produces new data in the form of input-output pairs. The overall process is embodied in an algorithm that combines support vector machines (SVMs) with active learning. SVMs use learning from examples (the examples are the input-output pairs generated by running the simulator) and a principle called maximum margin to derive predictors that generalize well to new inputs. In SimLearn, the SVM plays the role of modeling the knowledge that has been gained through previous simulation trials. Active learning is used to determine which new input points would be most informative if their output were known. The selected input points are run through the simulator to generate new information that can be used to refine the SVM. The process is then repeated. SimLearn carefully balances exploration (semi-randomly searching around the input space) versus exploitation (using the current state of knowledge to conduct a tightly focused search). During each iteration, SimLearn uses not one, but an ensemble of SVMs. Each SVM in the ensemble is characterized by different hyper-parameters that control various aspects of the learned predictor - for example, whether the predictor is constrained to be very smooth (nearby points in input space lead to similar output predictions) or whether the predictor is allowed to be "bumpy." The various SVMs will have different preferences about which input points they would like to run through the simulator next. SimLearn includes a formal mechanism for balancing the ensemble SVM preferences so that a single choice can be made for the next set of trials.

Burl, Michael↗

NASA NTRS1988

Remote sensing of ocean color in the Arctic

The main objectives of the research are: to increase the understanding of biological production (and carbon fluxes) along the ice edge, in frontal regions, and in open water areas of the Arctic and the physical factors controlling that production through the use of satellite and aircraft remote sensing techniques; and to develop relationships between measured radiances from the Multichannel Aircraft Radiometer System (MARS) and the bio-optical properties of the water in the Arctic and adjacent seas. Several recent Coastal Zone Color Scanner (CZCS) studies in the Arctic have shown that, despite constraints imposed by cloud cover, satellite ocean color is a useful means of studying mesoscale physical and biological oceanographic phenomena at high latitudes. The imagery has provided detailed information on ice edge and frontal processes such as spring breakup and retreat of the ice edge, influence of ice on ice effects of stratification on phytoplankton production, river sediment transport, effects of spring runoff, water mass boundaries, circulation patterns, and eddy formation in Icelandic waters and in the Greenland, Barents, Norwegian, and Bering Seas.

Maynard, N. G.↗

NASA NTRS1996

(abstract) Detection of Mesoscale Oceanic Phenomena in the Southern California Bight via ERS-1 SAR

ERS-1 SAR images are examined with the intent of identifying mesoscale oceanic phenomena in the Southern California Bight (SCB). The SCB is a region of dynamic physical and biological processes, and as such has long been studied. The ERS-1 SAR images are augmented with other remote sensing data, including SIR-C SAR, AVHRR, ERS-1 ATSR, and Space Shuttle hand-held photography. Analysis of these images has revealed a more dynamic mesoscale field than was previously suspected. Eddies with scales on the order of 20-30 km in diameter have been the most common mesoscale features evident, but the presence of oceanic fronts and internal waves, as well as atmospheric internal waves, have been documented as well. The multisensor data record will provide insight as to the underlying ocean and meterological conditions that lead to the prevalence especially of the eddies in this region.

Southern California Bight SCB remote sensing data ↗

NASA NTRS2022

Co-leveraging Scientific Advances in Space Biology and Astrobiology Towards Achieving NASA’s Life Science Objectives

Executive Summary: Distinct lines of scientific inquiry drives the separation of NASA’s fundamental life science research into Space Biology and Astrobiology. This division developed as a way to place life scientists alongside experts in the physical constraints that define the acclimation, adaptation and evolution of biology systems relevant to their respective subjects. For astrobiology, integration with disciplines such as geology, geochemistry, astronomy, planetary science, etc., enables a comprehensive assessment of the physical environment and its co-evolution with biological processes. Space Biology’s co-location with Physical Sciences places life science researchers adjacent to experts in the physical phenomena associated with microgravity and spaceflight, enabling an understanding of how the spaceflight environment affects biological systems. Despite this separation, aspects of both disciplines have converged on a similar, fundamental objective: to describe and understand the dynamics of complex living communities in the contexts of their physical environments. While the environmental systems and timescales are dramatically different, continuing to motivate the separation into distinct fields, similarities in the underlying objective present opportunities to find efficiencies, reduce overlap, and minimize duplication of effort. Space Biology and Astrobiology share a common need to understand microbial physiology in extreme environments – whether the ‘built’ spaceflight environment or the natural environments in which many astrobiology studies are conducted. In particular, open questions in each discipline require the development of quantitative frameworks, applicable at the ecosystem level, that support predictive capabilities for environments where observations are sparse. Additionally, both disciplines have a need to prepare, detect, and analyze the (potential) biological signal in complex samples-often in a completely autonomous fashion. The next decade will see NASA Space Biology moving to understand and describe the effects of the beyond low-earth orbit (BLEO) spaceflight environment on living systems. This new direction will dramatically reduce the opportunities for ground-based analysis of space-flown samples, driving space biology investigations towards fully autonomous experiments and missions. At the same time, astrobiology life detection missions aimed at detecting biosignatures on Mars and icy moons in the outer solar system could benefit from fully automated sample processing and analysis. There are opportunities to leverage instrument and method development between both disciplines within the context of these BLEO missions.

Astrobiology↗

NASA NTRS2015

Observation Platform for Dynamic Biomedical and Biotechnology Experiments Using the International Space Station (ISS) Light Microscopy Module (LMM)

Techshot, Inc., has developed an observation platform for the LMM on the ISS that will enable biomedical and biotechnology experiments. The LMM Dynamic Stage consists of an electronics module and the first two of a planned suite of experiment modules. Specimens and reagent solutions can be injected into a small, hollow microscope slide-the heart of the innovation-via a combination of small reservoirs, pumps, and valves. A life science experiment module allows investigators to load up to two different fluids for on-orbit, real-time image cytometry. Fluids can be changed to initiate a process, fix biological samples, or retrieve suspended cells. A colloid science experiment module conducts microparticle and nanoparticle tests for investigation of colloid self-assembly phenomena. This module includes a hollow glass slide and heating elements for the creation of a thermal gradient from one end of the slide to the other. The electronics module supports both experiment modules and contains a unique illuminator/condenser for bright and dark field and phase contrast illumination, power supplies for two piezoelectric pumps, and controller boards for pumps and valves. This observation platform safely contains internal fluids and will greatly accelerate the research and development (R&D) cycle of numerous experiments, products, and services aboard the ISS.

Kurk, Michael A. (Andy)↗

NASA NTRS2015

Observation Platform for Dynamic Biomedical and Biotechnology Experiments Using the International Space Station (ISS) Light Microscopy Module (LMM)

Kurk, Michael A. (Andy)↗

NASA NTRS1996

Gravity related features of plant growth behavior studied with rotating machines

Research in plant physiology consists mostly of studies on plant growth because almost everything a plant does is done by growing. Most aspects of plant growth are strongly influenced by the earth's gravity vector. Research on those phenomena address scientific questions specifically about how plants use gravity to guide their growth processes.

NASA Discipline Plant Biology↗

NASA NTRS2016

Levitation Technology in International Space Station Research

The International Space Station (ISS) is a unique multidisciplinary orbiting laboratory for science and technology research, enabling discoveries that benefit life on Earth and exploration of the universe. ISS facilities for containerless sample processing in Materials Science experiments include levitation devices with specimen positioning control while reducing containment vessel contamination. For example, ESA's EML (ElectroMagnetic Levitator), is used for melting and solidification of conductive metals, alloys, or semiconductors in ultra-high vacuum, or in high-purity gaseous atmospheres. Sample heating and positioning are accomplished through electromagnetic fields generated by a coil system. EML applications cover investigation of solidification and microstructural formation, evaluation of thermophysical properties of highly reactive metals (whose properties can be very sensitive to contamination), and examination of undercooled liquid metals to understand metastable phase convection and influence convection on structural changes. MSL utilization includes development of novel light-weight, high-performance materials. Another facility, JAXA's ELF (Electrostatic Levitation Furnace), is used to perform high temperature melting while avoiding chemical reactions with crucibles by levitating a sample through Coulomb force. ELF is capable of measuring density, surface tension, and viscosity of samples at high temperatures. One of the initial ELF investigations, Interfacial Energy-1, is aimed at clarification of interfacial phenomena between molten steels and oxide melts with industrial applications in control processes for liquid mixing. In addition to these Materials Science facilities, other ISS investigations that involve levitation employ it for biological research. For example, NASA's "Magnetic 3D Culturing and Bioprinting" investigation uses magnetic levitation for three-dimensional culturing and positioning of magnetized cells to generate spheroid assemblies for biomedical applications. Levitation is also used as a modeled microgravity ground analog in the NASA OsteoOmics ISS investigation, which tests whether magnetic levitation accurately simulates microgravity conditions by studying gravitational regulation of osteoblast and osteoclast genomics and metabolism. Elucidating the cellular mechanisms of bone loss in microgravity contributes to the understanding of bone loss in medical disorders on Earth, which may lead to development of preventive or therapeutic countermeasures. Thus, the ISS state-of-the-art laboratory offers various levitation capability platforms with applications for innovative research in Materials and Life Sciences disciplines, with benefits for humanity.

Guinart-Ramirez, Y.↗

NASA NTRSDate not supplied

TPSAS-NF1676L-11084-DND

The solar radiation must be considered as the primary factor when we study the climatic system because it provides almost all energy that drives the climatic system and most atmospheric phenomena. The solar radiation at the TOA is partially transferred, transformed into other forms of energy that are eventually dissipated by the general circulation of the atmosphere and oceans, and partially used in chemical and biological processes. The absorption of solar energy in the atmosphere (Acol) plays a key role in the climate system, not only because it affects the amount of solar energy absorbed by the Earth system, but also because it changes the vertical distribution of absorbed energy, which in turn impacts surface evaporation, atmospheric convection and precipitation. To investigate Acol, we have collected the collocated satellite-surface observations over the 35 selected BSRN surface sites during the period 2000-2004. The surface radiation budgets are averaged from the BSRN Shortwave (SW) observations over a 1-hour interval centered at the time of the NASA Terra and Aqua satellites overpass, and the TOA radiation budgets are averaged from the closest FOV satellite data to the BSRN stations. Then the atmospheric column SW absorption will be inferred from the satellite TOA albedo and BSRN surface absorption (through the estimated surface albedo). Monthly means of Acol, TOA albedo, and surface absorption have been calculated under both clear- and all-sky conditions over the 35 selected BSRN sites which represent different climate regimes. To evaluate the GCM simulations, we have collected the ECHAM5-HAM simulated surface, TOA and atmospheric radiation budgets by researchers at ETH Zurich and compared those simulations with observations. The preliminary comparisons have shown that the ECHAM5 simulated clear-sky surface absorption, TOA albedo, and ACOL agree very well (1-3%) with observations. Under all-sky conditions, they have strong correlations with CERES-derived cloud fraction. The simulated surface absorption is lower and TOA albedo is higher than those under clear skies, but ACOL does not increase too much. However, there are relatively large differences over some regions and months. A further study is needed.

X. Dong↗