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At least 19 records

Phase-Shifting Liquid Crystal Interferometers for Microgravity Fluid Physics

The initial focus of this project was to eliminate both of these problems in the Liquid Crystal Point-Diffraction Interferometer (LCPDI). Progress toward that goal will be described, along with the demonstration of a phase shifting Liquid Crystal Shearing Interferometer (LCSI) that was developed as part of this work. The latest LCPDI, other than a lens to focus the light from a test section onto a diffracting microsphere within the interferometer and a collimated laser for illumination, the pink region contained within the glass plates on the rod-mounted platform is the complete interferometer. The total width is approximately 1.5 inches with 0.25 inches on each side for bonding the electrical leads. It is 1 inch high and there are only four diffracting microspheres within the interferometer. As a result, it is very easy to align, achieving the first goal. The liquid crystal electro-optical response time is a function of layer thickness, with thinner devices switching faster due to a reduction in long-range viscoelastic forces between the LC molecules. The LCPDI has a liquid crystal layer thickness of 10 microns, which is controlled by plastic or glass microspheres embedded in epoxy 'pads' at the corners of the device. The diffracting spheres are composed of polystyrene/divinyl benzene polymer with an initial diameter of 15 microns. The spheres deform slightly when the interferometer is assembled to conform to the spacing produced by the microsphere-filled epoxy spacer pads. While the speed of this interferometer has not yet been tested, previous LCPDIs fabricated at the Laboratory for Laser Energetics switched at a rate of approximately 3.3 Hz, a factor of 10 slower than desired. We anticipate better performance when the speed of these interferometers is tested since they are approximately three times thinner. Phase shifting in these devices is a function of the AC voltage level applied to the liquid crystal. As the voltage increases, the dye in the liquid crystal tends to become more transparent, thus introducing a rather large amount of error into the phase-shifting measurement. While that error can be greatly reduced by normalization, we prefer eliminating the source of the error. To that end, we have pursued development of a 'blend' of custom dyes that will not exhibit these properties. That goal has not yet been fully achieved. Guardalben, et al, presented a similar set of interferograms in a paper partially funded by this grant. Shearing interferometers are a second class of common path interferometers. Typically they consist of a thick glass plate optimized for equal reflection from the front and back surface. While not part of the original thrust of the project, through the course of laboratory work, we demonstrated a prototype of a shearing interferometer capable of phase shifting using a commercial liquid crystal retardation plate. A schematic of this liquid crystal shearing interferometer (LCSI) and a sample set of interferograms are in the reference. This work was also supported by the U.S. Department of Energy Office of Inertial Confinement Fusion under Cooperative Agreement No. DE-FC03-92SF19460, the University of Rochester, and the New York State Energy Research and Development Authority. The support of DOE does not constitute an endorsement by DOE of the views expressed in this article. Additional information is included in the original extended abstract.

Griffin, DeVon W.

Coordinated Fuel Cell System Programs for Government and Commercial Applications: Are We in a New Era?

Though the fuel cell was invented in 1839, it was not until the early 1960's that the fuel cell power system was developed and used for a real application, for the NASA Space Mission Gemini. Unfortunately, fuel cell power systems did not, as a result, become in widespread use. Nevertheless, a great deal of progress has been made by both government and industry, culminating in many successful fuel cell power system demonstrations. Initially, each government agency and each private organization went its own way. Later, it became evident that coordination among programs was essential. An overview is presented of the current coordinated efforts by government and industry in fuel cells, with a sufficient historical background. The primary barriers to coordination of programs were institutional and differing application requirements. Initially, in the institutional area, it was the energy crisis and the formation of DOE which fostered close working relationships among government, manufacturers, and users. The authors discuss the fuel cell power system programs (of NASA, DOE, DOT, DOC, EPRI, GRI, industry, and universities), including missions and applications, technology advances, and demonstrations. The discussion covers the new Solar Regenerative Fuel Cell (RFC) program which has space, defense, and commercial terrestrial applications, and which is an excellent example of both program coordination and the Clinton Administration's dual-use application policy.

Warshay, Marvin

Wind Tunnel Testing Techniques for a Tandem Tilt-Wing, Distributed Electric Propulsion VTOL Aircraft

Urban Air Mobility (UAM) vertical takeoff and landing (VTOL) aircraftdesigns frequently include multiple distributed propulsors, complex wing-propulsor aerodynamics, significant airframe configuration changes during normal flight operations, and no historical database regarding the best ways to transition between vertical and horizontal flight. This paper describes the methodology used for wind tunnel testing of the Langley Aerodrome No. 8 (LA-8) in the NASA Langley 12-Foot Low-SpeedTunnel during multiple test entries in 2019 and2020. The LA-8 is a tandem tilt-wing aircraft with 4 motor-propellerunits and 4 control surfaces distributed across each wing, plus an inverted V-tail with 2 ruddervators on the fuselage. An initial tunnel entryused one-factor-at-a-time (OFAT) testing to (1) define candidate trimmed transition corridors between vertical and horizontal flight, (2) assess whether there was adequate control authority, and (3) define appropriatetest factor ranges for subsequent design of experiment (DOE) wind tunnel testing. The total number of independent variables for these wind tunnel tests (23) made DOE testing an efficient option for assessing the large number of potential interactions associated with the LA-8. The general advantages and disadvantages of OFAT and DOE wind tunnel testing techniques are also discussed –along with the benefits of a combined approach

wind tunnel research techniques

Advanced Gas Turbine (AGT) Technology Development Project annual report

This report is the tenth in a series of Technical Summary reports for the Advanced Gas Turbine (AGT) Technology Development Project, authorized under NASA Contract DEN3-167, and sponsored by the Department of Energy (DOE). This report was prepared by Garrett Turbine Engine Company, A Division of the Garrett Corporation, and includes information provided by Ford Motor Company, the Carborundum Company, and AiResearch Casting Company. The Project is administered by Mr. Thomas N. Strom, Project Manager, NASA-Lewis Research Center, Cleveland, Ohio. This report covers plans and progress for the period July 1, 1984 through June 30, 1985.

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Advanced Gas Turbine (AGT) Technology Development Project

This report is the eleventh in the series of Technical Summary reports for the Advanced Gas Turbine (AGT) Technology Development Project, authorized under NASA Contract DEN3-167, and sponsored by the Department of Energy (DOE). This report was prepared by Garrett Turbine Engine Company, A Division of the Garrett Corporation, and includes information provided by Ford Motor Company, the Standard Oil Company, and AiResearch Casting Company. This report covers plans and progress for the period July 1, 1985 through June 30, 1986. Technical progress during the reported period was highlighted by the 85-hour endurance run of an all-ceramic engine operating in the 2000 to 2250 F temperature regime. Component development continued in the areas of the combustion/fuel injection system, regenerator and seals system, and ceramic turbine rotor attachment design. Component rig testing saw further refinements. Ceramic materials showed continued improvements in required properties for gas turbine applications; however, continued development is needed before performance and reliability goals can be set.

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Implementing Production Grids

We have presented the essence of experience gained in building two production Grids, and provided some of the global context for this work. As the reader might imagine, there were a lot of false starts, refinements to the approaches and to the software, and several substantial integration projects (SRB and Condor integrated with Globus) to get where we are today. However, the point of this paper is to try and make it substantially easier for others to get to the point where Information Power Grids (IPG) and the DOE Science Grids are today. This is what is needed in order to move us toward the vision of a common cyber infrastructure for science. The author would also like to remind the readers that this paper primarily represents the actual experiences that resulted from specific architectural and software choices during the design and implementation of these two Grids. The choices made were dictated by the criteria laid out in section 1. There is a lot more Grid software available today that there was four years ago, and various of these packages are being integrated into IPG and the DOE Grids. However, the foundation choices of Globus, SRB, and Condor would not be significantly different today than they were four years ago. Nonetheless, if the GGF is successful in its work - and we have every reason to believe that it will be - then in a few years we will see that the 28 functions provided by these packages will be defined in terms of protocols and MIS, and there will be several robust implementations available for each of the basic components, especially the Grid Common Services. The impact of the emerging Web Grid Services work is not yet clear. It will likely have a substantial impact on building higher level services, however it is the opinion of the author that this will in no way obviate the need for the Grid Common Services. These are the foundation of Grids, and the focus of almost all of the operational and persistent infrastructure aspects of Grids.

Johnston, William E.

What should DOE do to help establish voluntary consensus standards for measuring and rating the performance of PV modules?

In response to concern expressed by the photovoltaics community over progress toward the establishment and issuance of concensus standards on photovoltaic performance measurements, a review of the status of and progress in developing these standards was conducted. It examined the roles of manufacturers, and consumers and the national laboratories funded by the U.S. Department of Energy (DOE) in supporting this effort. This was done by means of a series of discussions with knowledgeable members of the photovoltaic community. Results of these interviews are summarized and a new approach to managing support of standards activity is recommended that responds to specific problems found in the performance measurement standards area. The study concludes that there is a positive role to be played by the U.S. Department of Energy in establishing collector performance measurement standards. It recommends that DOE continue to provide direct financial support for selected committees and for research at national laboratories, and that management of the activity be restructured to increase the authority and responsibility of the consensus committees.

Runkle, L. D.

Directed Design of Experiments (DOE) for Determining Probability of Detection (POD) Capability of NDE Systems (DOEPOD)

This viewgraph presentation reviews some of the problems that are encountered by designers of Non-Destructive Examination (NDE) have in determining the probability of detection. According to the author "[the] NDE community should not blindly accept statistical results due to lack of knowledge." This is an attempt to bridge the gap between people doing NDE, and statisticians.

Generazio, Edward R.

Kilopower-nuclear electric propulsion for outer solar system exploration (NEP Benefits Study)

This report does not represent an endorsement by any of the contributing laboratories or a commitment to undertake any of the work described herein. The report identifies suggestions for further study but presents no recommendations regarding programmatic or project implementation. The authors and their supporting laboratories fully understand that such matters are the sole prerogative of the sponsoring agencies, i.e., National Aeronautics and Space Administration (NASA) and Department of Energy (DOE).

Casani, John R.

Bibliography of NASA-related publications on wind turbine technology 1973-1995

A major program of research and development projects on wind turbines for generating electricity was conducted at the NASA Lewis Research Center from 1973 to 1988. Most of these projects were sponsored by the U.S. Department of Energy (DOE), as a major element of its Federal Wind Energy Program. One other large-scale wind turbine project was sponsored by the Bureau of Reclamation of the Department of Interior (DOI). The peak years for wind energy work at Lewis were 1979-80, when almost 100 engineers, technicians, and administrative personnel were involved. From 1988 their conclusion in 1995, NASA wind energy activities have been directed toward the transfer of technology to commercial and academic organizations. Wind energy activities at NASA can be divided into two broad categories which are closely related and often overlapping: (1) Designing, building, and testing a series of 12 large-scale, experimental, horizontal-axis wind turbines (HAWT's); and (2) conducting supporting research and technology (SR&T) projects. The purpose of this bibliography is to assist those active in the field of wind energy in locating the technical information they need on wind power planning, wind loads, turbine design and analysis, fabrication and installation, laboratory and field testing, and operations and maintenance. This bibliography contains approximately 620 citations of publications by over 520 authors and co-authors. Sources are: (1) NASA reports authored by government grantee, and contractor personnel, (2) papers presented by attendees at NASA-sponsored workshops and conferences, (3) papers presented by NASA personnel at outside workshops and conferences, and (4) outside publications related to research performed at NASA/ DOE wind turbine sites.

Spera, David A.

Improvement of Automated POST Case Success Rate Using Support Vector Machines

During early conceptual design of complex systems, concept down selection can have a large impact upon program life-cycle cost. Therefore, any concepts selected during early design will inherently commit program costs and affect the overall probability of program success. For this reason it is important to consider as large a design space as possible in order to better inform the down selection process. For conceptual design of launch vehicles, trajectory analysis and optimization often presents the largest obstacle to evaluating large trade spaces. This is due to the sensitivity of the trajectory discipline to changes in all other aspects of the vehicle design. Small deltas in the performance of other subsystems can result in relatively large fluctuations in the ascent trajectory because the solution space is non-linear and multi-modal. In order to help capture large design spaces for new launch vehicles, the authors have performed previous work seeking to automate the execution of the industry standard tool, Program to Optimize Simulated Trajectories (POST). This work initially focused on implementation of analyst heuristics to enable closure of cases in an automated fashion, with the goal of applying the concepts of design of experiments (DOE) and surrogate modeling to enable near instantaneous throughput of vehicle cases.3 As noted in [4] work was then completed to improve the DOE process by utilizing a graph theory based approach to connect similar design points.

Zwack, Mathew R.

Improvement of Automated POST Case Success Rate Using Support Vector Machines

During early conceptual design of complex systems, concept down selection can have a large impact upon program life-cycle cost. Therefore, any concepts selected during early design will inherently commit program costs and affect the overall probability of program success. For this reason it is important to consider as large a design space as possible in order to better inform the down selection process. For conceptual design of launch vehicles, trajectory analysis and optimization often presents the largest obstacle to evaluating large trade spaces. This is due to the sensitivity of the trajectory discipline to changes in all other aspects of the vehicle design. Small deltas in the performance of other subsystems can result in relatively large fluctuations in the ascent trajectory because the solution space is non-linear and multi-modal [1]. In order to help capture large design spaces for new launch vehicles, the authors have performed previous work seeking to automate the execution of the industry standard tool, Program to Optimize Simulated Trajectories (POST). This work initially focused on implementation of analyst heuristics to enable closure of cases in an automated fashion, with the goal of applying the concepts of design of experiments (DOE) and surrogate modeling to enable near instantaneous throughput of vehicle cases [2]. Additional work was then completed to improve the DOE process by utilizing a graph theory based approach to connect similar design points [3]. The conclusion of the previous work illustrated the utility of the graph theory approach for completing a DOE through POST. However, this approach was still dependent upon the use of random repetitions to generate seed points for the graph. As noted in [3], only 8% of these random repetitions resulted in converged trajectories. This ultimately affects the ability of the random reps method to confidently approach the global optima for a given vehicle case in a reasonable amount of time. With only an 8% pass rate, tens or hundreds of thousands of reps may be needed to be confident that the best repetition is at least close to the global optima. However, typical design study time constraints require that fewer repetitions be attempted, sometimes resulting in seed points that have only a handful of successful completions. If a small number of successful repetitions are used to generate a seed point, the graph method may inherit some inaccuracies as it chains DOE cases from the non-global-optimal seed points. This creates inherent noise in the graph data, which can limit the accuracy of the resulting surrogate models. For this reason, the goal of this work is to improve the seed point generation method and ultimately the accuracy of the resulting POST surrogate model. The work focuses on increasing the case pass rate for seed point generation.

Zwack, Matthew R.

NASA’s Radioisotope Power Systems Program: Status Update

Radioisotope power systems (RPS) have safely been in use in the United States for over 60 years. RPS-enabled NASA missions have utilized space nuclear power to explore planets, moons, and interstellar space. This exploration resulted in changes to our understanding of our Solar System and our place within it. In 2010, NASA HQ established a NASA program to invest in RPS technologies and systems that could enable future missions. The RPS Program ensures the availability of RPS for the exploration of the solar system in environments where conventional solar or chemical power generation is impractical or impossible. The RPS Program, in partnership with the Department of Energy (DOE) Office of Nuclear Energy continues to operate as an interagency partnership to provide robust power system solutions to spacecrafts that conduct missions for exploration and science that otherwise would not be feasible. This paper provides a synopsis of current activities after well over a decade of formal interagency partnering.

Radioisotope

Analysis of Atmospheric Aerosol Data Sets and Application of Radiative Transfer Models to Compute Aerosol Effects

The Bay Area Environmental Research Institute (BAER) scientists have worked with the NASA Ames Research Center sunphotometer group led by Dr. Philip Russell for many years researching the climatic effects of aerosol particles in the stratosphere and troposphere. We have continued to work with the NASA Ames sunphotometer group in research activities representing funded, peer-reviewed proposals to NASA, NOAA and DOE. The activities are described in those proposals and also in the documents provided to the Grants Office earlier. This is the final report from January 1,2002 - June 30, 2005. The report consists of a compilation of 41 peer-reviewed publications (published, in press or submitted) produced under this Cooperative Agreement and 43 first-authored conference presentations. To save paper, reprints are not included but will, of course, be provided upon request.

Schmid, Beat

Augmenting Parametric Optimal Ascent Trajectory Modeling with Graph Theory

It has been well documented that decisions made in the early stages of Conceptual and Pre-Conceptual design commit up to 80% of total Life-Cycle Cost (LCC) while engineers know the least about the product they are designing [1]. Once within Preliminary and Detailed design however, making changes to the design becomes far more difficult to enact in both cost and schedule. Primarily this has been due to a lack of detailed data usually uncovered later during the Preliminary and Detailed design phases. In our current budget-constrained environment, making decisions within Conceptual and Pre-Conceptual design which minimize LCC while meeting requirements is paramount to a program's success. Within the arena of launch vehicle design, optimizing the ascent trajectory is critical for minimizing the costs present within such concerns as propellant, aerodynamic, aeroheating, and acceleration loads while meeting requirements such as payload delivered to a desired orbit. In order to optimize the vehicle design its constraints and requirements must be known, however as the design cycle proceeds it is all but inevitable that the conditions will change. Upon that change, the previously optimized trajectory may no longer be optimal, or meet design requirements. The current paradigm for adjusting to these updates is generating point solutions for every change in the design's requirements [2]. This can be a tedious, time-consuming task as changes in virtually any piece of a launch vehicle's design can have a disproportionately large effect on the ascent trajectory, as the solution space of the trajectory optimization problem is both non-linear and multimodal [3]. In addition, an industry standard tool, Program to Optimize Simulated Trajectories (POST), requires an expert analyst to produce simulated trajectories that are feasible and optimal [4]. In a previous publication the authors presented a method for combatting these challenges [5]. In order to bring more detailed information into Conceptual and Pre-Conceptual design, knowledge of the effects originating from changes to the vehicle must be calculated. In order to do this, a model capable of quantitatively describing any vehicle within the entire design space under consideration must be constructed. This model must be based upon analysis of acceptable fidelity, which in this work comes from POST. Design space interrogation can be achieved with surrogate modeling, a parametric, polynomial equation representing a tool. A surrogate model must be informed by data from the tool with enough points to represent the solution space for the chosen number of variables with an acceptable level of error. Therefore, Design Of Experiments (DOE) is used to select points within the design space to maximize information gained on the design space while minimizing number of data points required. To represent a design space with a non-trivial number of variable parameters the number of points required still represent an amount of work which would take an inordinate amount of time via the current paradigm of manual analysis, and so an automated method was developed. The best practices of expert trajectory analysts working within NASA Marshall's Advanced Concepts Office (ACO) were implemented within a tool called multiPOST. These practices include how to use the output data from a previous run of POST to inform the next, determining whether a trajectory solution is feasible from a real-world perspective, and how to handle program execution errors. The tool was then augmented with multiprocessing capability to enable analysis on multiple trajectories simultaneously, allowing throughput to scale with available computational resources. In this update to the previous work the authors discuss issues with the method and solutions.

Patrick D Dees

Enabling Open and Interoperable Science: Multi-Omics Data Processing Platform with NASA GeneLab Standardized Bioinformatics Workflows for Space and Earth Research

Multi-omics biological data continues to be generated at an astounding pace. Genomics, transcriptomics, metabolomics, and proteomics, or collectively known as multi-omics data, are used to assess biological functions, and provide invaluable insights into human, animal, plant, and environmental health both on Earth and in Space. Despite the abundance of these valuable data, the need for bioinformatics expertise, particularly as it relates to the niche filed of space biology, and a lack of accessible resources for processing these data limit their usefulness in deriving biological insights. The NASA Open Science Data Repository (OSDR) provides access to omics data from various spaceflight and analog studies. To enhance the accessibility and reusability of these data, GeneLab (part of OSDR) designs and implements standardized, community-driven, open-source bioinformatics workflows to transform raw omics data into standardized processed data. Currently, GeneLab-processed data from hundreds of space studies have been reused for meta-analyses. This has led to new insights and scientific publications that extend beyond the initial research, thereby enriching our understanding of molecular-scale biological responses to the space environment. To make these bioinformatics workflows open and accessible, GeneLab teamed up with DOE-funded initiatives, including the National Microbiome Data Collaborative (NMDC), to create the NASA EDGE [Empowering the Development of Genomics Expertise] Bioinformatics web-based platform. NASA EDGE utilizes shared compute resources to run the GeneLab standardized bioinformatics workflows, which eliminates the need for researchers to have their own high performance computing cluster. The web-based platform makes complicated biological analyses incredibly easy to perform, thus expanding the reach of these analyses to bioinformatics novices, students, and even citizen scientists enabling them to contribute to scientific discoveries and progress. The authors will demonstrate how the NASA EDGE platform can be used to process microbial omics data hosted on OSDR as well as user-generated omics datasets using GeneLab’s standard workflows.

Amanda M. Saravia-Butler

Preliminary risk benefit assessment for nuclear waste disposal in space

This paper describes the recent work of the authors on the evaluation of health risk benefits of space disposal of nuclear waste. The paper describes a risk model approach that has been developed to estimate the non-recoverable, cumulative, expected radionuclide release to the earth's biosphere for different options of nuclear waste disposal in space. Risk estimates for the disposal of nuclear waste in a mined geologic repository and the short- and long-term risk estimates for space disposal were developed. The results showed that the preliminary estimates of space disposal risks are low, even with the estimated uncertainty bounds. If calculated release risks for mined geologic repositories remain as low as given by the U.S. DOE, and U.S. EPA requirements continue to be met, then no additional space disposal study effort in the U.S. is warranted at this time. If risks perceived by the public are significant in the acceptance of mined geologic repositories, then consideration of space disposal as a complement to the mined geologic repository is warranted.

Rice, E. E.

2015 Space Radiation Standing Review Panel

The 2015 Space Radiation Standing Review Panel (from here on referred to as the SRP) met for a site visit in Houston, TX on December 8 - 9, 2015. The SRP met with representatives from the Space Radiation Element and members of the Human Research Program (HRP) to review the updated research plan for the Risk of Radiation Carcinogenesis Cancer Risk. The SRP also reviewed the newly revised Evidence Reports for the Risk of Acute Radiation Syndromes Due to Solar Particle Events (SPEs) (Acute Risk), the Risk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure (CNS Risk), and the Risk of Cardiovascular Disease and Other Degenerative Tissue Effects from Radiation (Degen Risk), as well as a status update on these Risks. The SRP would like to commend Dr. Simonsen, Dr. Huff, Dr. Nelson, and Dr. Patel for their detailed presentations. The Space Radiation Element did a great job presenting a very large volume of material. The SRP considers it to be a strong program that is well-organized, well-coordinated and generates valuable data. The SRP commended the tissue sharing protocols, working groups, systems biology analysis, and standardization of models. In several of the discussed areas the SRP suggested improvements of the research plans in the future. These include the following: It is important that the team has expanded efforts examining immunology and inflammation as important components of the space radiation biological response. This is an overarching and important focus that is likely to apply to all aspects of the program including acute, CVD, CNS, cancer and others. Given that the area of immunology/inflammation is highly complex (and especially so as it relates to radiation), it warrants the expansion of investigators expertise in immunology and inflammation to work with the individual research projects and also the NASA Specialized Center of Research (NSCORs). Historical data on radiation injury to be entered into the Watson “big data” study must be used with caution. The general scientific issues of reproducibility, details of experimental methods and data analysis from preclinical and basic research laboratories have been raised broadly over the last few years (not specific to this work) and indicate that caution must be applied in the ways these data are used. This pertains to preclinical data and also to phase 3 clinical trials in radiation oncology and medical oncology. Of course, appropriate use and analysis of these “big-data” sets also offer the potential of pinpointing limitations and extracting remaining useful information. Emphasis should be placed on the latter possibility. A key target is risk reduction from radiation exposure. Progress of the entire space program, now moving towards the Mars mission, requires timely answers to key components of human risk, which are known to be complex. Periodic review of progress should be conducted with additional resources directed into achieving critical milestones. Turning the long red bars to yellow and green (or for some risks such as CNS possibly to grey) must be high priority. That such progress will require new science and not engineering means that it should be viewed in a knowledge-based light. The technology-based aspects of engineering issues are certainly as important, however, science and knowledge-based problems are solved in a different way than engineering. Timelines for engineering are more predictable, while for science, progress can be methodical with occasional major incremental findings that can rapidly change the rate of progress. As opportunities for rapid incremental changes arise, periodic enhancement of investment is strongly recommended to enable such new knowledge to be quickly and efficiently exploited. Collaborations and linkages with National Institute of Allergy and Infectious Diseases (NIAID), the Biomedical Advanced Research and Development Authority (BARDA) and the Department of Defense (DoD) are in place and more are encouraged, where possible, with the radiation injury and medical countermeasure studies. This could include utilizing some of their animal model testing contracts to facilitate obtaining results using common platforms. Such approach will facilitate the comparison of results among laboratories, and will facilitate and accelerate the development of medical countermeasures. It is particularly noteworthy that the NASA Space Radiation Element is reaching out to the Multidisciplinary European Low Dose Initiative (MELODI) platform coordinating low dose radiation risk research, and to other international agencies that are studying low dose radiation effects in an effort to fill the void generated by the cancelation of the Department of Energy (DOE) low dose radiation program. While NASA is working actively with NIAID and BARDA to integrate their relevant findings of radiation mitigator investigations to NASA programs, the committee notes its disappointment that the United States currently lacks a dedicated low dose radiation program with clear mechanistic orientation and aimed at the quantification and mitigation of human radiation risk on Earth. This void gives to the NASA Space Radiation Program Element special societal value, but also makes its overall design more challenging.

Steinberg, Susan