Search NASASearch

SEARCH · Search NASA

Results for “Effectiveness”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 records

Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects

The goal of this review is to summarize the evidence for non-targeted and delayed effects of exposure to ionizing radiation in vivo. Currently, human health risks associated with radiation exposures are based primarily on the assumption that the detrimental effects of radiation occur in irradiated cells. Over the years a number of non-targeted effects of radiation exposure in vivo have been described that challenge this concept. These include radiation-induced genomic instability, bystander effects, clastogenic factors produced in plasma from irradiated individuals that can cause chromosomal damage when cultured with nonirradiated cells, and transgenerational effects of parental irradiation that can manifest in the progeny. These effects pose new challenges to evaluating the risk(s) associated with radiation exposure and understanding radiation-induced carcinogenesis.

Review, Tutorial

The calibration of photographic and spectroscopic films: 1: A microscopic analysis of IIaO films. 2: The effects of agitation and soaking on IIaO films. 3: The effects of electric field on IIaO films. 4: The effects of X-ray radiation on IIaO films

The grain structure of the emulsion using both reflected and transmission light was examined along with the effects of soaking. The effect of a static charge by a Tesla-coil, and the effects of airport equipment, and dental X-rays on the film were also analyzed.

Hammond, E. C., Jr.

Final Report for The Creation of a Physics-based Ground-effect Model, Phase 2 - Inclusion of the Effects of Wind, Stratification, and Shear into the New Ground Effect Model

The reduction of the separation of the leading and following aircrafts is desirable to enhance the airport capacity provided that there is a physics-based operational model applicable to all regions of the flight domain (out of ground effect, OGE; near ground effect, NGE; and in ground effect, IGE) and that the quality of the quantitative input from the measurements of the prevailing atmospheric conditions and the quality of the total airport operations regarding the safety and the sound interpretation of the prevailing conditions match the quality of the analysis and numerical simulations. In the absence of an analytical solution, the physics of the flow is best expressed by a mathematical model based on numerical simulations, field and laboratory experiments, and heuristic reasoning. This report deals with the creation of a sound physics-based real-time IGE model of the aircraft wake vortices subjected to crosswind, stratification and shear.

Sarpkaya, Turgut

Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation?

A number of nontargeted and delayed effects associated with radiation exposure have now been described. These include radiation-induced genomic instability, death-inducing and bystander effects, clastogenic factors and transgenerational effects. It is unlikely that these nontargeted effects are directly induced by cellular irradiation. Instead, it is proposed that some as yet to be identified secreted factor can be produced by irradiated cells that can stimulate effects in nonirradiated cells (death-inducing and bystander effects, clastogenic factors) and perpetuate genomic instability in the clonally expanded progeny of an irradiated cell. The proposed factor must be soluble and capable of being transported between cells by cell-to-cell gap junction communication channels. Furthermore, it must have the potential to stimulate cellular cytokines and/or reactive oxygen species. While it is difficult to imagine a role for such a secreted factor in contributing to transgenerational effects, the other nontargeted effects of radiation may all share a common mechanism.

Non-NASA Center

Tank tests to determine the effect of varying design parameters of planing-tail hulls II : effect of varying depth of step, angle of after- body keel, length of afterbody chine, and gross load

The second part of a series of tests made in Langley tank no. 2 to determine the effect of varying design parameters of planing-tail hulls is presented. Results are given to show the effects on resistance characteristics of varying angle of afterbody keel, depth of step, and length of afterbody chine. The effect of varying the gross load is shown for one configuration. The resistance characteristics of planing-tail hulls are compared with those of a conventional flying-boat hull. The forces on the forebody and afterbody of one configuration are compared with the forces on a conventional hull. Increasing the angle of afterbody keel had small effect on hump resistance and no effect on high-speed resistance but increased free-to-trim resistance at intermediate speeds. Increasing the depth of step increased hump resistance, had little effect on high-speed resistance, and increased free-to-trim resistance at intermediate speeds. Omitting the chines on the forward 25 percent of the afterbody had no appreciable effect on resistance. Omitting 70 percent of the chine length had almost no effect on maximum resistance but broadened the hump and increased spray around the afterbody. Load-resistance ratio at the hump decreased more rapidly with increasing load coefficient for the planing-tail hull than for the representative conventional hull, although the load-resistance ratio at the hump was greater for the planing-tail hull than for the conventional hull throughout the range of loads tested. At speeds higher than hump speed, load-resistance ratio for the planing-tail hull was a maximum at a particular gross load and was slightly less at heavier and lighter gross loads. The planing-tail hull was found to have lower resistance than the conventional hull at both the hump and at high speeds, but at intermediate speeds there was little difference. The lower hump resistance of the planing-tail hull was attributed to the ability of the afterbody to carry a greater percentage of the total load while maintaining a higher value of load-resistance ratio.

HULLS - RESISTANCE - TANK TESTS (NACA-#2)

Proton Effects and Test Issues for Satellite Designers: Ionization Effects - Section 4

This portion of the Short Course is divided into two segments to separately address the two major proton-related effects confronting satellite designers: ionization effects and displacement damage effects. While both of these topics are deeply rooted in "traditional" descriptions of space radiation effects, there are several factors at play to cause renewed concern for satellite systems being designed today. For example, emphasis on Commercial Off-The-Shelf (COTS) technologies in both commercial and government systems increases both Total Ionizing Dose (TID) and Single Event Effect (SEE) concerns. Scaling trends exacerbate the problems, especially with regard to SEEs where protons can dominate soft error rates and even cause destructive failure. In addition, proton-induced displacement damage at fluences encountered in natural space environments can cause degradation in modern bipolar circuitry as well as in many emerging electronic and opto-electronic technologies. A crude, but nevertheless telling, indication of the level of concern for proton effects follows from surveying the themes treated in papers presented at this conference. The table lists themes found in the IEEE Transaction on Nuclear Science (TNS) December issue from the past year and compares them with the December issue's content a decade earlier. Ten years ago there were nine papers, or about 10% of the total, dealing with the four indicated topics. At that time, single event effects from protons were the primary concern, and these were thought to be possible only when a nuclear reaction initiated energetic recoil atoms. This is shown in the table as the 'traditional" SEE subject. A decade later, submissions addressing this topic had doubled, while papers devoted to displacement damage studies had increased from one to nine! More importantly, displacement damage effects in the natural space environments have become a concern for degradation in modern devices (other than solar cells), and this was not so ten years earlier.

Marshall, Paul W.

Effects of Cloud Horizontal Inhomogeneity and Drizzle on Remote Sensing of Cloud Droplet Effective Radius: Case Studies Based on Large-eddy Simulations

This study investigates effects of drizzle and cloud horizontal inhomogeneity on cloud effective radius (re) retrievals from the Moderate Resolution Imaging Spectroradiometer (MODIS). In order to identify the relative importance of various factors, we developed a MODIS cloud property retrieval simulator based on the combination of large-eddy simulations (LES) and radiative transfer computations. The case studies based on synthetic LES cloud fields indicate that at high spatial resolution (100 m) 3-D radiative transfer effects, such as illumination and shadowing, can induce significant differences between retrievals ofre based on reflectance at 2.1 m (re,2.1) and 3.7 m (re,3.7). It is also found that 3-D effects tend to have stronger impact onre,2.1 than re,3.7, leading to positive difference between the two (re,3.72.1) from illumination and negative re,3.72.1from shadowing. The cancellation of opposing 3-D effects leads to overall reasonable agreement betweenre,2.1 and re,3.7 at high spatial resolution as far as domain averages are concerned. At resolutions similar to MODIS, however, re,2.1 is systematically larger than re,3.7when averaged over the LES domain, with the difference exhibiting a threshold-like dependence on bothre,2.1and an index of the sub-pixel variability in reflectance (H), consistent with MODIS observations. In the LES cases studied, drizzle does not strongly impact reretrievals at either wavelength. It is also found that opposing 3-D radiative transfer effects partly cancel each other when cloud reflectance is aggregated from high spatial resolution to MODIS resolution, resulting in a weaker net impact of 3-D radiative effects onre retrievals. The large difference at MODIS resolution between re,3.7 and re,2.1 for highly inhomogeneous pixels with H 0.4 can be largely attributed to what we refer to as the plane-parallelrebias, which is attributable to the impact of sub-pixel level horizontal variability of cloud optical thickness onre retrievals and is greater for re,2.1 than re,3.7. These results suggest that there are substantial uncertainties attributable to 3-D radiative effects and plane-parallelre bias in the MODIS re,2.1retrievals for pixels with strong sub-pixel scale variability, and theH index can be used to identify these uncertainties.

Zhang, Zhibo

Non-targeted and delayed effects of exposure to ionizing radiation: I. Radiation-induced genomic instability and bystander effects in vitro

A long-standing dogma in the radiation sciences is that energy from radiation must be deposited in the cell nucleus to elicit a biological effect. A number of non-targeted, delayed effects of ionizing radiation have been described that challenge this dogma and pose new challenges to evaluating potential hazards associated with radiation exposure. These effects include induced genomic instability and non-targeted bystander effects. The in vitro evidence for non-targeted effects in radiation biology will be reviewed, but the question as to how one extrapolates from these in vitro observations to the risk of radiation-induced adverse health effects such as cancer remains open.

Review, Tutorial

Thrust reversing effects on horizontal tail effectiveness of twin-engine fighter aircraft

The Langley Research Center has conducted an experimental program to determine the interference effects of thrust reversing on horizontal tail effectiveness of a twin engine, general research fighter model at approach (Mach number 0.15) and in-flight (Mach number 0.60 and 0.90) speeds. Twin vertical tails were tested at three longitudinal locations. Two nonaxisymmetric nozzle reverser concepts were studied. The effects of thrust reversing on horizontal tail effectiveness were found to be very dependent upon vertical tail locations. At approach speeds thrust reverser operation usually resulted in large variations in horizontal tail effectiveness as either nozzle pressure ratio or model angle of attack was varied. Either increases or decreases in tail effectiveness ocurred due to reverse operation depending upon tail location. At in-flight conditions there were always decreases in tail effectiveness due to reverser operation regardless of vertical tail location.

Capone, F. J.

Atmospheric effects on TM measurements - Characterization and comparison with the effects on MSS

The effects of the earth's atmosphere on the Thematic Mapper (TM) measurements are studied with two radiative transfer models. A doubling model is used to compute the effective reflectance of the earth-atmosphere system, as measured by the TM for the reflective bands. An emission-transmission model is used to compute the satellite-received radiance for the thermal band. The influences of the aerosol loading, the amount of water vapor, and the solar illumination angle on the effective reflectance are investigated. The effect of varying atmospheric water vapor on the measurements of the thermal band is studied. The scattering and absorption effects on TM bands are compared with those on Multispectral Scanner System (MSS) bands. While the changes in the aerosol loading introduce comparable variation of the effective reflectance for both sensors, the changes in the water vapor amount give less impact on TM4 than MSS7.

Kiang, R. K.

Characterization of a novel epigenetic effect of ionizing radiation: the death-inducing effect

The detrimental effects associated with exposure to ionizing radiation have long been thought to result from the direct targeting of the nucleus leading to DNA damage; however, the emergence of concepts such as radiation-induced genomic instability and bystander effects have challenged this dogma. After cellular exposure to ionizing radiation, we have isolated a number of clones of Chinese hamster-human hybrid GM10115 cells that demonstrate genomic instability as measured by chromosomal destabilization. These clones show dynamic and persistent generation of chromosomal rearrangements multiple generations after the original insult. We hypothesize that these unstable clones maintain this delayed instability phenotype by secreting factors into the culture medium. To test this hypothesis we transferred filtered medium from unstable cells to unirradiated GM10115 cells. No GM10115 cells were able to survive this medium. This phenomenon by which GM10115 cells die when cultured in medium from chromosomally unstable GM10115 clones is the death-inducing effect. Medium transfer experiments indicate that a factor or factors is/are secreted by unstable cells within 8 h of growth in fresh medium and result in cell killing within 24 h. These factors are stable at ambient temperature but do not survive heating or freezing, and are biologically active when diluted with fresh medium. We present the initial description and characterization of the death-inducing effect. This novel epigenetic effect of radiation has implications for radiation risk assessment and for health risks associated with radiation exposure.

Non-NASA Center

Effective medium approximation for effective propagation constant calculation in a dense random medium

The effective medium approximation (EMA) formalism developed for scalar wave calculations in solid state physics is generalized to electromagnetic wave scattering in a dense random medium. Results are applied to compute the effective propagation constant in a dense medium involving discrete spherical scatterers. When compared with a common quasicrystalline approximation (QCA), it is found that EMA accounts for backward scattering and the effect of correlation among three scatterers which are not available in QCA. It is also found that there is not much difference in the calculated normalized phase velocity between the use of these two approximations. However, there is a significant difference in the computed effective loss tangent in a nonabsorptive random medium. The computed effective loss tangent using EMA and measurements from a snow medium are compared, showing good agreement.

Zhu, P. Y.

Effective propagation constants in dense random media under effective medium approximation

The effective medium approximation is applied to study the effective propagation constants in a dense random medium. The dyadic Green's function is introduced to establish the effective medium approximation formalism for electromagnetic waves. The multiple scattering equations and the Lippmann-Schwinger equations for the transition operator are obtained in the configuration average form. The dispersion equations of multiple scattering is derived by using a standard method in quantum mechanics. To obtain an expression for the effective propagation constants the matrix elements of the configuration average dyadic transiton operator are calculated in momentum representation. Numerical illustations are carried out to demonstrate the difference in the effective propagation constants between the use of this approximation and the well-known quasi-crystalline approximation. A comparison is made with measured loss tangent in dry snow.

Zhu, P. Y.

Propulsion-induced effects caused by out-of-ground effects

Propulsion induced effects encountered by moderate- to high-disk loading STOVL or VSTOL aircraft out-of-ground effect during hover and transition between hover and wing-borne flight are discussed. Descriptions of the fluid flow phenomena are presented along with an indication of the trends obtained from experimental investigations. In particular, three problem areas are reviewed: (1) the performance losses sustained by a VSTOL aircraft hovering out-of-ground effect, (2) the induced aerodynamic effects encountered as a VSTOL aircraft flies on the combination of powered and aerodynamic lifts between hover and cruise out-of-ground effect, and (3) the aerodynamic characteristics caused by deflected thrust during maneuvering flight over a wide range of both angle of attack and Mach number.

Margason, Richard

Propulsion-induced effects caused by out-of-ground effects

Propulsion induced effects encountered by moderate- to high-disk loading STOVL or VSTOL aircraft out-of-ground effect during hover and transition between hover and wing-borne flight are discussed. Descriptions of the fluid flow phenomena are presented along with an indication of the trends obtained from experimental investigations. In particular, three problem areas are reviewed: (1) the performance losses sustained by a VSTOL aircraft hovering out-of-ground effect, (2) the induced aerodynamic effects encountered as a VSTOL aircraft flies on the combination of powered and aerodynamic lifts between hover and cruise out-of-ground effect, and (3) the aerodynamic characteristics caused by deflected thrust during maneuvering flight over a wide range of both angle of attack and Mach number.

Margason, Richard

Some effects of dust on photometry of high-z galaxies: Confounding the effects of evolution

Photometric observations of very distant galaxies--e.g., color vs. z or magnitude vs. z, have been used over the past decade or so in investigations into the evolution of the stellar component. Numerous studies have predicted significant color variations as a result of evolution, in addition to the shifting of different rest wavelengths into the band of observation. Although there is significant scatter, the data can be fit with relatively straightforward, plausible models for galaxian evolution. In very few cases are the effects of dust extinction included in the models. This is due in a large part to the uncertainty about the distribution and optical properties of the grains, and even whether or not they are present in significant numbers in some types of galaxies such as ellipticals. It is likely that the effects of dust on broadband observations are the greatest uncertainty in studies of very distant galaxies. We use a detailed Monte Carlo radiative transfer model within a spherical geometry for different star/dust distributions to examine the effects of dust on the broadband colors of galaxies as a function of redshift. The model fully accounts for absorption and angular redistribution in scattering. In this summary, we consider only the effects on color vs. redshift for three simple geometries each with the same total dust optical depth. Elsewhere at this conference, Capuano, Thronson, & Witt consider other effects of altering the relative dust/star distribution.

Thronson, H. A., Jr.