Responses to preoptic temperature manipulation in the awake and hibernating marmot
Responses of normothermic and hibernating marmots to manipulations of the preoptic-hypothalamic temperature (T-PO) were experimentally investigated. An exponential increase in open-loop gain (OLG) occurred with decreases in temperature; it is concluded that this response can be explained by recruitment of cold-sensitive neurons brought about by low-temperature inactivation of inhibitory neurons. Marmots not only seek out the hibernating state, but also utilize all the thermoregulatory means they possess to remain in it for a given period of time.